• Journal of Chest Surgery
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• v.32 no.6
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• pp.579-583
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• 1999

Background: Thoracic sympathicotomy has been used safely and successfully to manage palmar hyperhidrosis. The preoperative and postoperative recording of Sympathetic Skin Responses(SSR) was performed for objective evaluation and follow-up of thoracic sympathicotomy in hyperhidrosis patients, and also for ascertaining the clinical usefullness of SSR. Material and Method: The recording of SSR was performed on 15 patients suffering from palmar hyperhidrosis with Medelec Sapphire Plus electromyogragh before and after thoracic sympathicotomy. Eletrical stimuli on the right median nerve was made in patients in supine position and results were recorded on right and left palms with soles at the same time by 4 channels. Skin temperatures were also monitored simultaneously. T2,3 sympathicotomy was performed with VATS in every patients. SSR was done in 2 patients one month later. Result: Clinically, all patients had symptomatic improvement with satisfaction. Postoperative complication was small amount of residual pneumothorax in 5 patients but it was absorbed sponteneously. There was no recurrence during follow-up period and ten patients(66%) complained compensatory hyperhidrosis. After operation, SSR change was shown in every 15 patients. Abolition of SSR on both palms was achieved in 12 patients(80%) and on both soles in 6 patients. In the other 3 patients, the latencies were significantly delayed and the amplitudes were significantly reduced at both palms and soles. In two patients who were examined at one month later after operation, similar results with postoperative SSRs were shown. The skin temperature on preoperative both palm and sole were lower than normal temperature, and those on postoperative both palm and sole were increased. Those had statistical significance(p<0.05), and the temperature on the palm was increased higher that than on the sole. Conclusion: After thoracic sympathicotomy was performed on palmar hyperhidrosis patients, an increment of skin temperatures and SSR changes were achieved at both palms and soles of all patients. Palmar SSRs were completely abolished in 12 patients(80%), and similar results of postoperative SSRs were achieved. The recording of SSR may be useful to easily and objectively assess the completeness of sympathicotomy and the follow-up of recurrence in hyperhidrosis patients.

• Journal of Chest Surgery
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• v.42 no.6
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• pp.738-743
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• 2009

Background: There is no standardized tool and parameter that can accurately assess the sympathetic function before and after performing sympathectomy in patients with primary palmar hyperhidrosis. We examined the effective-ness of the sympathetic skin response (SSR) study for documenting the change of sympathetic denervation before and after performing selective thoracic sympathicotomy. Material and Method: We prospectively investigated the SSR from 12 healthy subjects who were diagnosed with primary hyperhidrosis. Each SSR was recorded on the right palm or sole with electrical stimuli applied to the skin at the left wrist and foot and vice versa for the controlateral side. This test was performed before, 2 weeks and 1 year after selective thoracic sympathicotomy. The data was corrected for the onset latency and the amplitude of the SSR (n=24). Result: The mean age of the 12 patients was $24.6{\pm}0.4$ years (range: 19~36) and the gender ratio was 1 : 0.7. The mean values of the preoperative, postoperative 2 weeks and postoperative 1 year onset latency and amplitude of the palmar side (n=24) were $1.46{\pm}0.24$ msec and $6,043{\pm}2,339{\mu}V$, $1.63{\pm}0.42$ msec and $823{\pm}638{\mu}V$, and $1.44{\pm}0.39$ msec and $2,412{\pm}1,546{\mu}V$, respectively. The mean values of the plantar side (n=38) were $1.83{\pm}0.42$ msec and $2,816{\pm}1,694{\mu}V$, $2.16{\pm}0.39$ msec and $1,445{\pm}1,281{\mu}V$ and $1.95{\pm}0.25$ msec and $1,622{\pm}865{\mu}V$, respectively. Among the documented parameters, only the palmar amplitude (p=0.002) showed statistical significance in recording the change of the sympathetic system within the same individual for the pre and postoperative period. Conclusion: The SSR amplitude ratio may be a useful parameter for documenting the efficacy of sympathetic denervation after selective sympathicotomy.

• Proceedings of the KTCVS Conference
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• 1998.10a
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• pp.119-119
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• 1998

• Proceedings of the Korean Society of Computer Information Conference
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• 2013.07a
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• pp.359-360
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• 2013

본 연구에서는 외부 자극과 내적인 교감신경의 변화에 따라 나타나는 땀 반응으로 얻어진 생체신호를 다루었다. 즉, 땀 반응을 지칭하는 피부전도도를 측정할 수 있는 시스템과, 더불어 차량 운전시 혹은 운동 등의 동적 자극에 의한 영향을 최소화하여 교감신경에 의한 피부전도도의 신뢰도를 높일 수 있는 방안을 강구하였다. 기존의 두 개의 전극 간 리지스턴스(Resistance)를 측정하는 방식을 내부에서 분리된 한 개의 전극을 사용하여 신체적 움직임의 제한점을 해소하고 피부전도도로 나타난 생체신호가 외적인 움직임에 따른 영향인지 내적인 신경의 변화에 따른 영향인지를 추정할 수 있는 모듈을 개발하였다. 20명의 건강한 청년을 대상으로 피실험하여 기존의 생체신호 측정 장비인 MP-150의 EDA모듈과 동시 측정한 결과, 두 데이터가 약 88% 일치하는 것으로 확인하였다.

• Proceedings of the KTCVS Conference
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• 1998.10a
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• pp.118-118
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• 1998

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 2001.05a
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• pp.313-319
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• 2001

본 연구는 시뮬레이터 실험에서 필수적으로 발생하는 Simulator Sickness(SS)를 평가하기 위하여 동적 시뮬레이터에서 일정한 속도(60km/h)로 1시간 주행했을 때 Simulator Sickness Questionnaire(SSQ)를 이용하여 주관적 Sickness를 평가하고 생리적 반응으로 심박 변동량(HRV)과 피부온도 및 피부저항을 측정하여 성별, Simulator 수준에 따라 비교 분석하였다. 분석 결과 동적 시뮬레이터에서 주행시 주관적인 Simulator Sickness는 안정에 비해 시간이 지남에 따라 45분까지 선형적으로 증가하여UT고, 여자와 sick군이 남자와 nonsick군에 비해 더 높았으며 sickness 수준간에서는 유의성이 나타났지만 남녀간의 유의한 차이는 없었다. 생리적 반응은 시간에 따른 변화는 없었으나 안정에 비해 R-R 간격의 감소, (LF+MF)/total 및 (LF+MF)/HF의 증가로부터 교감 신경이 활성화되었으며 피부온도의 감소와 피부저항의 증가로부터 긴장도가 커짐을 알 수 있었다. 주행 50분 이후는 HF/total가 감소하여 부교감 신경의 작용이 저하되는 것으로 나타났다.. 성별, sickness수준에 따라서는 남녀간에는 부분적으로 유의한 차이가 있었고 평균 R-R 간격에서만 sick군이 nonsick군보다 유의하게 낮았다.

• Science of Emotion and Sensibility
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• v.5 no.4
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• pp.51-57
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• 2002

The purpose of the study was to measure and compare driver's psychophysiological responses in different driving conditions through driving simulator. Twelve male adults(more than 1 year of driving experience) were assigned to four different driving conditions, such as normal speed(70㎞/h), sudden start(0㎞/h→70㎞/h), and sudden stop(70㎞/h→0㎞/h), and their simulator sickness, subjective pleasantness and arousal, EEG, ECG, skin temperature, and GSR were measured. Subjective and physiological evaluations were executed before and after driving in each condition. The results showed that subjective pleasantness and arousal increased in sudden stop and sudden start conditions, relative to stop and normal speed conditions. As the central nervous responses, beta wave increased and alpha wave decreased in sudden stop and sudden start conditions, relative to stop and normal speed conditions. With regard to the autonomic responses, heart rate and GSR increased, while skin temperature decreased in sudden stop and sudden start conditions, which means an activation of sympathetic nervous system. The results suggested that based upon observation of the distinctive psychophysiological changes by driving conditions, it is possible to evaluate the human sensibility in dynamic environment.

• Science of Emotion and Sensibility
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• v.3 no.2
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• pp.103-112
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• 2000

본 연구는 Graphic simulator에서 자동차 속도 변화에 따른 운전자의 감성변화를 주관적 평가와 자율신경계의 반응을 통해 알아보고자 한다. 속도 변화는 정차(0km/h), 40km/h, 100km/h, 160km/h로 제시하였고, 건강한 10명의 피험자를 대상으로 심박변화율, 피부저항, 피부온도, 맥파 등의 생리신호를 측정하였다. 본 연구 목적에 적절한 속도 관련 어휘를 추출하여 각 속도에서의 주관적 감성 변화를 평가하였다. 또한, 각 속도 실험 전 후에 Simulator Sickness를 측정하여 Simulator Sickness가 실험 결과에 미치는 영향을 분석하였다. 속도가 증가함에 따라 긴장도와 쾌도가 증가한다는 주관적 평가 결과를 얻었다. 실험 전에 비해 실험 후의 Simulator Sickness 값은 증가하였지만 실험 전, 후의 통계적 차이는 관찰할 수 없었다. 속도 증가에 따라, 평균 R-R간격, 피부온도의 진폭은 감소하였고, 피부저항은 증가하였고, 맥파의 평균 진폭은 감소하였다. 그러므로 본 연구를 통해 Simulator Sickness의 큰 영향 없이 Graphic Simulator에서 속도의 증가에 따라 교감신경계가 활성화됨을 관찰할 수 있었고, 이는 실제 동적 환경에서 속도 변화에 따른 자율신경계의 반응 및 주관적 평가 결과와 일치하는 것이다. 향후 복합 감각 자극이 가능한 시뮬레이터가 구축이 될 것이고, 이를 통해 보다 현실감 있는 동적 환경 제시와 감성 측정이 가능할 것이다.

• Science of Emotion and Sensibility
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• v.17 no.3
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• pp.29-38
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• 2014

The purpose of this study was to verify human physiological responses to emotional lighting system using LED (light emitting diode) flat lighting. Subjects were ten males in their twenties without medical history to eyes. Colors of LED lighting are red, orange, yellow, green, blue, purple and colorless (white). They were stimulated by LED lighting for 5 minutes. We measured body temperature, heart rate variability (HRV) and electroencephalogram (EEG) before and after color stimulus. In case of EEG analysis, relative power ${\alpha}$ wave ratio decreased in the groups of colorless, red and orange color light. Also, sympathetic nerve was more activated than parasympathetic nerve and the body temperature was increased in the groups of colorless, red, orange, yellow color light. On the other hand, relative power ${\alpha}$ wave ratio increased and parasympathetic nerve was more activated than sympathetic nerve and the body temperature was decreased in the groups of green, blue and purple color light. The results imply that the LED color lighting system in the realistic experiment environment. In the future, studies with compounded both colors and modes according to situation or auditory as nature sound or olfactory as aroma will be required.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 1999.11a
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• pp.433-437
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• 1999

본 연구는 도로표면의 기복 또는 굴곡의 변화가 자동차 탑승자에게 미치는 자율신경계의 반응을 관찰하고자 하였다. 아스팔트, 시멘트, 비포장도로를 각각 30 km/h의 속력으로 정속 주행하면서 ECG, GSR, Skin Temperature 의 생리변화를 3분간 측정하였고, 주행 후에는 각각의 도로 주행시 느꼈던 감성의 변화를 주관적 평가지로 검정하였다. 건강한 5명의 지원자가 이 실험에 참여하였고 도로표면의 기복의 변화로부터 유발되는 감성에만 집중하도록 요구하여 다른 간섭효과로부터 유발되는 감성의 변화를 최소화하도록 하였다. 정차에 비해 각 도로 주행시 피험자는 아스팔트, 시멘트, 비포장도로 순서로 불쾌도와 긴장도가 증가하였다고 주관적 평가를 하였다. 또한 아스팔트, 시멘트, 비포장도로 순서로 평균 R-R 간격이 점차 감소하였고, GSR의 진폭은 증가하였으며, 피부온도는 감소하였다. 본 연구로부터 도로표면의 기복의 정도가 증가할수록 교감신경계가 활성화된다는 사실을 관찰할 수 있었고 이러한 결과는 주관적 평가결과와도 일치하였다.