• Journal of Life Science
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• v.25 no.8
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• pp.953-959
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• 2015

Optogenetics is the combination of optical and molecular strategies to control designated molecular and cellular activities in living tissues and cells using genetically encoded light-sensitive proteins. It involves the use of light to rapidly gate the membrane channels that allows for ion movement. Optogenetics began with the placing of light-sensitive proteins from green algae inside specific types of brain cells. The cells can then be turned on or off with pulses of blue and yellow light. Using the naturally occurring algal protein Channelrhodopsin-2 (ChR2), a rapidly gated light-sensitive cation channel, the number and frequency of action potentials can be controlled. The ChR2 provides a way to manipulate a single type of neuron while affecting no others, an unprecedented specificity. This technology allows the use of light to alter neural processing at the level of single spikes and synaptic events, yielding a widely applicable tool for neuroscientists and biomedical engineers. An improbable combination of green algae, lasers, gene therapy and fiber optics made it possible to map neural circuits deep inside the brain with a precision that has never been possible before. This will help identify the causes of disorders like depression, anxiety, schizophrenia, addiction, sleep disorder, and autism. Optogenetics could improve upon existing implanted devices that are used to treat Parkinson’s disease, obsessive-compulsive disorder and other ailments with pulses of electricity. An optogenetics device could hit more specific subsets of brain cells than those devices can. Applications of optogenetic tools in nonneuronal cells are on the rise.

• Journal of the Korean Vacuum Society
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• v.10 no.3
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• pp.380-386
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• 2001

A nuclear microprobe system with adjustable precision object slits and a magnetic quadrupole doublet was designed by the beam optics simulation using a first order matrix formalism, and installed in a $30^{\circ}$ beam line connected with KIGAM 1.7 MV Tandem VDG Accelerator. Demagnification factors for x and y axis are calculated to be 25 and 4.9, respectively, and a minimum beam spot side is expected to be about 5 $\mu\textrm{m}$ for 3 MeV proton beams with a current of about 1 nA. A multi-purpose octagonal target chamber has been built to facilitate MeV ion-beam analytical techniques of PIXE, RBS, ERDA, and ion beam micro-machining. It contains X-ray and particle detectors, a zoom microscope, a Faraday cup, a 4-axis sample manipulator and a high vacuum pumping system. The system performance of the nuclear microprobe is now being tested, and automatic manipulator control and data acquisition system will be installed for routine applications of micro ion-beam analytical techniques.

• Journal of the Korean earth science society
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• v.38 no.7
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• pp.535-545
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• 2017

Maritime accidents around the Korean Peninsula are increasing, and the ship detection research using remote sensing data is consequently becoming increasingly important. This study presented a new ship detection algorithm using hyperspectral images that provide the spectral information of several hundred channels in the ship detection field, which depends on high resolution optical imagery. We applied a spectral matching algorithm between the reflection spectrum of the ship deck obtained from two field observations and the ship and seawater spectrum of the hyperspectral sensor of an airborne visible/infrared imaging spectrometer. A total of five detection algorithms were used, namely spectral distance similarity (SDS), spectral correlation similarity (SCS), spectral similarity value (SSV), spectral angle mapper (SAM), and spectral information divergence (SID). SDS showed an error in the detection of seawater inside the ship, and SAM showed a clear classification result with a difference between ship and seawater of approximately 1.8 times. Additionally, the present study classified the vessels included in hyperspectral images by presenting the adaptive thresholds of each technique. As a result, SAM and SID showed superior ship detection abilities compared to those of other detection algorithms.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.48 no.5
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• pp.391-399
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• 2020

KASI (Korea Astronomy and Space Science Institute) has been developing the multipurpose laser tracking system with three functions of satellite laser tracking, adaptive optics and space debris laser tracking for scientific research and national space missions. The space debris laser tracking system provides the distance to space debris without a laser retro-reflector array by using a high power pulse laser, which employs a spinning disk to change the optical path between the transmit and receive beams. The spinning disk causes the collision band which is unable to reflect the returned signal to a detector and then has an effect on the tracking coverage of space debris. This study proposed the mathematical model for tracking coverage by taking into account the various specifications of spinning disk such as disk size, spinning velocity and collision rate between the disk and hole. In addition, the spinning disk specifications were analyzed in terms of tracking coverage and collision band based on the mathematical model to investigate tracking requirements of the Geochang laser tracking system.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.42 no.1
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• pp.45-55
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• 2016

Light shows various optical behaviors such as reflection, absorption, and scattering on skin for individuals. In particular, reflection of light from the skin has been widely used as the brightness index of the skin of individuals through the measurement of the physical quantity of spectral reflectance. Therefore, the study of light behavior on skin would be useful for the preparation of new evaluation method in the development stage of make-up products. In this study, multi-dimensional analysis for spectral reflectance behavior of light on individual skin was performed using Kubelka-Munk model. Also, we analyzed the contribution of skin parameters such as skin thickness and hemoglobin, which could affect the spectral reflectance, using above model and literature information. Base on this, we calculated the theoretical reflectance of normal women for visual light, which showed good agreement with the measured reflectance. Our study of light propagation in skin based on Kubelka-Munk model provides useful insight for the development of personalized cosmetic in the near future.

• Current Optics and Photonics
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• v.4 no.1
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• pp.69-80
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• 2020

A Rayleigh Lidar used for wind detection works by transmitting laser pulses to the atmosphere and receiving backscattering signals from molecules. Because of the weak backscattering signals, a lidar usually uses a high sensitivity photomultiplier as detector and photon counting technology for signal collection. The capturing of returned extremely weak backscattering signals requires the lidar to work on dark background with a long time accumulation to get high signal-to-noise ratio (SNR). Because of the strong solar background during the day, the SNR of lidar during daytime is much lower than that during nighttime, the altitude and accuracy of detection are also restricted greatly. Therefore this article describes an ultra-narrow bandwidth filter (UNBF) that has been developed on 354.7 nm wavelength of laser. The UNBF is used for suppressing the strong solar background that degrades the performance of Rayleigh wind lidar during daytime. The optical structure of UNBF consists of an interference filter (IF), a low resolution Fabry-Perot interferometer (FPI) and a high resolution FPI. The parameters of each optical component of the UNBF are presented in this article. The transmission curve of the aligned UNBF is measured with a tunable laser. Contrasting the result of with-UNBF and with-IF shows that the solar background received by a Licel transient recorder decreases by 50~100 times and that the SNR with-UNBF was improved by 3 times in the altitude range (35 km to 40 km) compared to with-IF at 10:26 to 10:38 on August 29, 2018. By the SNR comparison at four different times of one day, the ratio-values are larger than 1 over the altitude range (25~50 km) in general, the results illustrate that the SNR with-UNBF is better than that with-IF for Rayleigh Lidar during daytime and they demonstrate the effective improvements of solar background restriction of UNBF.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.37 no.1
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• pp.27-36
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• 2000

As a potential approach for non-destructive testing of concrete structures, we evaluate the time-of-flight (TOF) ultrasound tomography technique In conventional X ray tomography, the reconstructed Image corresponds to the internal attenuation coefficient However, in TOF ultrasound tomography, the reconstructed Image is proportional to the retractive index of the medium Because refractive effects are minimal for X-rays, conventional reconstruction techniques are applied to reconstruct the Image in X-ray tomography However, since ultrasound travels in curved path, due to the spatial variations in the refractive index of the medium, the path must be known to correctly reconstruct the Image. Algorithm for determining the ultrasound path is developed from a Geometrical Optics point view and the image reconstruction algorithm, since the paths are curved It requires the algebraic approach, namely the ART or the SIRT Here, the difference between the computed and the measured TOP data is used as a basis, for the iteration process First the initial image is reconstructed assuming straight paths. It then updates the path based on the recently reconstructed image This process of reconstruction and path determination repeats until convergence The proposed algorithm is evaluated by computer simulations, and in addition is applied to a real concrete structure.

• Journal of The Korean Association For Science Education
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• v.37 no.6
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• pp.993-1003
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• 2017

Teachers expect team-based project learning to help students develop collaborative and real-world problem solving skills. In practice, however, students tend to solve problems with simple division of labor, and there is a tendency that learning transfer does not occur in solving problems. The purpose of this study is to develop a collaborative learning model based on the transactive memory system (TMS) and to verify its effectiveness. The collaborative learning model based on the TMS is composed of three stages. The first stage is developing TMS. In this stage, the students learn physics concepts and make knowledge about the expertise of group members through peer instruction. The second stage, activating TMS, is building trust through solving well-defined problems for developing near-transfer. And in the third stage, applying TMS, the students solve an ill-defined problem based on real-world context for practicing far-transfer. Based on this model, a 15-week program including two projects on geometric optics and sound waves was developed and applied to 60 college students. The data for five weeks of one project were collected and analyzed. As a result, the TMS of the experimental group with the TMS-based collaborative learning model improved stepwise. Whereas, the difference between the first week and the last week was statistically significant, while the TMS change of the comparison group using the general project learning model was not significant. Also, the experimental group showed that the learning transfer occurred better in the project than the comparison group. A collaborative learning model based on TMS can be used to learn how students gain synergy through collaboration and how students collaboratively transfer the learned concepts in problem solving.

• Journal of The Korean Association For Science Education
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• v.34 no.8
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• pp.755-765
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• 2014

The convergence and consilience in education (hereafter, interdisciplinary education) is receiving great attention from societies. This study aims to investigate the works of scientists and artists who have intended to combine science with the arts in the modern era, to take into account the socio-philosophical setbacks during the period, and to suggest pedagogical implications of science education as interdisciplinary education. The concept of interdisciplinary education stems from Plato's thought, idea, as a comprehensive and invariant truth. The renaissance, full of enrichment about scientific achievement, was based on Neo-Platonism pursuing holistic-synthetic approach. During the time, scientists presented in this study tried to find comprehensive principles and borrow useful method from the arts. In such a context, scientists not only made use of the arts for expression of scientific knowledge, but also drew conclusion by analogical reasoning between science and the arts. Artists, as well, relied upon anatomy and optics especially, to elaborate linear perspective and even developed their own scientific knowledge through personal experience. Hence, contemporary science education should encourage students to hold a holistic viewpoint about science and the arts, articulate explicit goals and outcomes as interdisciplinary education, implement meta-disciplinary instruction about science and the arts, and develop assessment framework for collaborative learning. There may be good examples for inter-disciplinary education as listed: illustrating scientific ideas through the arts and vice versa, organizing collaborative works and evaluations criteria for them, and stressing problem solving on a daily basis.

• Journal of the korean academy of Pediatric Dentistry
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• v.28 no.3
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• pp.363-368
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• 2001

It is well known that numerous factors influence the light output of curing units, but many dentists are un aware that the output of their curing lights are inadequate. This study was conducted to evaluate the light in tensity of visible-light curing units in some private dental clinics and hospital dental clinics. In order to determine the maximum light intensity of the curing units, lamps, filters and fiber optic bundles, they were replaced with new ones and light intensity was remeasured. Light intensity was measured by employing a digital radiometer (EFOS model #8000, USA). Light intensity ranged in $29\sim866mW/cm^2$ (below $150mW/cm^2$ ; 17.8%, $150\sim300mW/cm^2$ : 46.6%, above $300mW/cm^2$ ; 35.6%). The replacement of the components increased the light intensity, with maximum increases of 94.8% for lamps, 82.3% for filters, 200.8% for fiber optics and 361.5% for all three parts. According to the manufacturer of radiometer, curing light is considered as unsuitable for use with a reading of above $300mW/cm^2$ by the radiometer. Applying these criteria to the present study, 64.4% of the curing units required repair or replacement. The results of this study indicated that the light intensities of the curing units used in dental practice were lower than optimum level.