• Title/Summary/Keyword: 관원

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Metal Sequestering by a Poly(ethylenimine)-Sephadex G-25 Conjugate Containing 2,2'-Dihydroxyazobenzene

  • Gwan, Won Jong;Yu, Chang Eun;Jang, Won Seok;No, Yeong Seok;Seo, Jeong Hun
    • Bulletin of the Korean Chemical Society
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    • v.21 no.4
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    • pp.393-400
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    • 2000
  • 2,2¢-Dihydroxyazobenzene (DHAB) was attached to poly(ethylenimine) (PEI) to obtain DHAB-PEI. Spectral titration revealed that uranyl, Fe(III), Cu(II), and Zn(II) ion form 1 : 1-type complexes with DHAB attached to PEI. Formation constants for the metal complexes formed by the DHAB moieties of DHAB-PEI were mea-sured by using various competing ligands. The results indicated thatthe concentrations of uranyl, Fe(III), and Cu(II) ions can be reduced to 10 -16 -10 -23 M at p 8 with DHAB-PEI when the concentration of the DHAB moiety is 1 residue M. By using cyanuric chloride as the coupling reagent, DHAB-PEI was immobilized on Sephadex G-25 resin to obtain DHAB-PEI-Seph. Binding of uranyl,Fe(III), Cu(II), and Zn(II) ion by DHAB-PEI-Seph was characterized by using competing ligands. A new method has been developed for characteriza-tion of metal sequestering ability of a chelating resin. Formation constants and metal-binding capacity of two sets of binding sites on the resin were estimated for each metal ion. DHAB-PI-Seph was applied to recovery of metals such as uranium,Fe, Cu, Zn, Pb, V, Mn, and W from seawater. The uranium recovery from seawaterby DHAB-PEI-Seph does not meet the criterion for economical feasibility partlydue to interference by Fe and Zn ions. The seawater used in the experiment was contaminated by Fe and Zn and, therefore, the efficiency of uranium extractionfrom seawater with DHAB-PEI-Seph could be improved if the experiment is carried out in a cleaner sea.

Influence on the Anti-cancer and Immune response improvement of Herbal-acupuncture with Asparagus cochinchinensis infusion solution put into Chung-wan(CV12) and Kwanwon(CV4) (중완(中脘) 및 관원(關元)에 시술한 천문동약침이 항암 및 면역작용에 미치는 영향)

  • Jang, Suk-geun;Kang, Jae-hui;Yim, Yun-kyoung;Lee, Hyun;Lee, Byung-ryul
    • Journal of Acupuncture Research
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    • v.20 no.5
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    • pp.159-171
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    • 2003
  • Objective: To study on the anti-cancer, anti-metastasis and immune response improvement effects of Herbal-acupuncture with Asparagus cochinchinensis infusion solution. Methods: we put into Chung-wan(CV12) and Kwanwon(CV4) of C57bl/6 which are corresponding to human body with Asparagus coc hinchinensis infusion solution. We observed the effect on the expres sion of MMP-9. the expression of cytokine gene, number of pulmon ary colony, histological analysis on tissue metastasis of lung and liver. the expression of cytokine gene on PBMC. the number of $CD3e^+/CD4^+$. $CD3e^+/CD8^+$, $NK^+$ cell. Results: The results were obtained as follows I) The effect on expression of MMP-9. the expression of cytokine gen e was inhibited significantly in all the sample groups. compared with control group. 2) In pulmonary colony, sample groups were decreased significantly, compared with control group. especially, the group put into Chung-wan(CV12) was decreased significantly. 3) Histological analysis of sample groups inhibited significantly in all th e sample groups compared with that control groups in both of lung and liver. especially, the group put into Chung-wan(CV12) was inhibited significantly. 4) The effect on cytokine gene expression on PBMC of all the sample groups were increased significantly, compared with control group. 5) In flow cytometry, $CD3e^+/CD4^+$ $CD3e^+/CD8^+$, $NK^+$ cell in sample groups were increased compared with control group.

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The Backgrounds and Roles of the Science Educators during the Enlightenment Period of Korea (개화기 과학 교육자의 배경과 역할)

  • Park, Jon-Seok;Chung, Byung-Hoon
    • Journal of The Korean Association For Science Education
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    • v.20 no.3
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    • pp.443-454
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    • 2000
  • The compilers of science textbooks during the enlightenment period of Korea had been active in teaching and writing of science education. Thus a research on their social and educational backgrounds would help us to understand the historical process of the formation of Korean science education. In finding out their backgrounds, the official government resumes and the bulletins of an academic society were used. It was found that seven compilers of science textbooks, with their known resumes and bulletins, studied in Japan and another six studied in Korea. However, most students who studied in Japan with the support from Korean government returned to Korea and took an active part in education. In the first place, they had written the scientific articles in the bulletins. Then, they published school textbooks, including science textbooks. However, their roles in the science education replaced with the Japanese teachers with the lapse of time. Furthermore, since they were rather specialists in translation than in subject matters and studies applied sciences in technical colleges, they did little to foster science and could not form a firm basis for an independent internal structure of science education in Korea.

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양송시기(兩宋時期)의 의정사(醫政史)에 관한 연구

  • Park, Hyeon-Guk;Kim, Jae-Cheol;Kim, Gi-Uk
    • Journal of Korean Medical classics
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    • v.19 no.3
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    • pp.65-99
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    • 2006
  • 송대통치자희환의약병중견의학적발전. 축소궁정의료궤구(縮小宮廷醫療机構), 각확대평민의료여의약유관적자선궤구이개선백성의료조건적정책방향흔진보적. 장의적엄범지수집, 교정(校訂), 편찬(編纂), 반포이수존의학문헌(頒布以收存醫學文獻), 병차위의학적전파화보급작출봉헌. ${\ulcorner}$내경(內經)${\lrcorner}$, ${\ulcorner}$상한(傷寒)${\lrcorner}$ 등기초이론적연구방면상야운용(等基礎理論的硏究方面上也運用), 금원시기성위료학술쟁론적기출, 저시송대의정상최성공적정책(這是宋代醫政上最成功的政策). 유정부엄구약물, 수정본초병건립제약공창화약점(修訂本草幷建立製藥工廠和約店), 전매약물(專賣藥物), 개혁제형, 이발전'성약'(以發展'成葯'), 통일용약적규범등(統一用藥的范等), 저양적조시향약물적발전화의약적민중화흔대적영향. 의약교육방면상(醫藥敎育方面上), 재태의국화국자감리건립적'의학'교육제도유흔다건공, 궤구적예속, 전과(專科) 적분과(的分科), 고시제도(考試制度), 학교관리등도적료신경험(學校管理等都積了新驗), 의학상이'삼사법'(醫學上以'三舍法') '공액'위려의학교육적조시('貢額'爲勵醫學敎育的措施), 저치득긍정적(這値得肯定的). 송대의학교육상야유과착(宋代醫學敎育上也有過錯). 비여(譬如), 인제도적존폐이유실교육적연속성(因制度的存廢而有失敎育的連續性), 이방애의약교육경금적척축화계승(以妨碍醫藥敎育經驗的積蓄和繼承), 불단결핍잠력, 상실동력이차몰건립전문약학교육(喪失動力而且沒建立專門藥學敎育). 대부분수요의정궤구적건립(大部分需要醫政机構的建立). 단시유례속관사흔옹제적문제, 인위피상부소속궤관소견체소이불구통일적지도화협조, 최고의정궤구'한임의관원'야몰유통제의약궤구적권한(最高醫政机構'翰林醫官院'也沒有統制醫藥机構的權限), 직책중복(職責重複), 인원과잉(人員過剩), 의관원본신이야유흔다과잉리인원, 부구엄격적관리제도. 인비송대의관관리방면상강락료총효율(因比宋代醫官管理方面上降落了總效率).

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Proteolytic Properties of Cathepsin L, Chymotrypsin, and Trypsin from the Muscle and Viscera of Anchovy, Engraulis japonica (멸치 육과 내장으로부터 분리한 Cathepsin L, Chymotrypsin 및 Trypsin의 단백질분해 특성)

  • PYEUN Jae-Hyeung;HEU Min-Soo;CHO Deuk-Moon;KIM Hyeung-Rak
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.28 no.5
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    • pp.557-568
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    • 1995
  • Proteolytic properties of enzymes from the muscle and viscera of anchovy have been examined. Cathepsin L, chymotrypsin, and trypsin showed similar Km values for casein. However, they had higher Km values for myofibrillar proteins than those for casein. The $k_cat$ of cathepsin L and chymotrypsin for myofibrillar proteins were higher than that of trypsin, and also cathepsin L and chymotrypsin caused higher hydrolysis in myofibrillar proteins of anchovy and yellowtail. In the presence of sodium chloride$(0-25\%)$, proteolytic activity for myofibrillar proteins from yellowtail was higher than that for casein. Proteolytic activity was decreased with the increase of sodium chloride concentration. Cathepsin L had been less affected by NaCl concentration and temperature on the hydrolysis of myofibrillar proteins than chymotrypsin and trypsin. Cathepsin L and chymotrypsin were move responsible to the autolysis of muscle proteins from fish than trypsin.

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Effect of Moxibution at the Kwanwon, Chung-wan and Chok-samni on the blood picture in Rat with transportation stress (관원(關元).중완(中脘).족삼리(足三里) 애구(艾灸)가 수송(輸送) Stress를 준 Rat의 혈액상(血液狀)에 미치는 영향(影響))

  • Yang, Seung-Hee;Lee, Joon-Moo
    • The Journal of Internal Korean Medicine
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    • v.15 no.1
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    • pp.165-175
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    • 1994
  • Effects of moxibution at the Gwanweon, Jungwan and Joksamlee on the blood picture in rat with transportation stress were determined. Counts of RBC showed a tendency to increase from 6 hours to 12 hours after transportation stress, however in the moxibution group, showed no changes in counts of RBC after transportation stress and the tendency of fluctuation was similiar to those of none stress group. The changes in Hb after transportation stress showed no difference among moxibution group and none moxibution group, however the changes in PCV showed a tendency to increase from 3 hours to 6 hours after transportation stress in two stress group. In the mean values of erythrocytic blood during experimental times, counts of RBC showed a high values (P<.05) in the stress only group, however in the other groups, these values showed no difference (P>.05) among treatment and the values of Hb and PCV showed no difference among 4 treatment groups. In the two stress groups, counts of WBC and Neutrophils showed a tendency to decrease after transportation stress, however the moxibution group was recovered to normal Leukocytes condition on short time compared with those of none moxibution group. In the mean values of Leukocytes during experimental times, counts of WBC and Neutrophils showed a high values and Lymphocytes showed a low values in the stress only group compared with those of other groups, however the stress group with moxibution showed no difference in Leukocytes values compared with those of normal condition group. Monocytes, Basophils and Eosinophils showed no difference among 4 treatment groups(P>.05). Results from this study indicate that the moxibution can tolerate the effects of transportation stress in rat.

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A Study on the Modern Lighthouse of Busan Harbor in the late Joseon Dynasty after Opening Port (조선말 개항기 부산항의 근대식 등대에 관한 연구)

  • Ahn, Woong-Hee
    • Journal of Navigation and Port Research
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    • v.38 no.5
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    • pp.541-547
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    • 2014
  • Busan was known firstly to the western world in the end of 18th century. When the Joseon opened a port under the western powers in the late 19th century, Busan was an important port. The increasing number of international ship exchange had magnified the harbor facility and the importance of lighthouses of Busan port. Busan maritime customs officer were in charge of installation and management of lighthouses. The operations of maritime customs became historical origin of Joseon changing from feudal society to modern nation. The majority of the documents from maritime customs was disappeared. So it was hard to know the exact history. But investigating documents and papers of Joseon, even media records will enable us to establish the objective fact relations. Moreover, published and translated data from the past make it possible such investigations. As a result, modern lighthouse of Busan harbor in the late Joseon after opening port was could be found. It could be offered to establishing the Korean modern history as the objective data.

The network analysis of acupoints for primary dysmenorrhea (원발성 월경곤란 치료를 위한 경혈 및 경혈 조합의 네트워크 분석)

  • In-Seon Lee
    • Journal of Convergence Korean Medicine
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    • v.4 no.1
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    • pp.13-17
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    • 2022
  • Objectives: Primary dysmenorrhea is a representative disease that causes intestinal pain, and it has long been known that acupuncture treatment is effective. In this study, a network analysis was conducted using acupuncture points reported in the existing systematic literature review, and the combination of acupuncture points used to treat primary dysmenorrhea was analyzed. Methods: Among of a total of 60 papers, excluding those that used ear acupuncture, the analysis results indicated that combinations of BL23, BL40, BL25, BL60, BL30, Ashi-points, BL26, GB34, and GV3 were used in combination. Results: Through this, it can be seen that previous studies to reveal the effectiveness of acupuncture on back pain mainly used the acupoints of the bladder meridian (BL), local acupoints group, and distal acupoints group. Conclusion: In order to reveal the correlation between acupoints and therapeutic effects through future studies and to provide guidelines on the principles of selecting and combining acupoints, it is necessary to employ a quantitative analysis method for therapeutic effects and to provide detailed reports on acupoints.

A Research of the Needling Depth for Gaining Deqi and Quality of Those Sensation - In Chung-wan(CV12) and Kwan-wan(CV4) Loci, Often Used in Ob&Gy Treatment (부인과(婦人科)에서 상용하는 중완혈(中脘穴)과 관원혈(關元穴)의 득기감(得氣感)을 느끼는 자침(刺鍼) 깊이와 득기감(得氣感) 발현 양상에 대한 연구)

  • Maeng, Yu-Sook;Kwon, Su-Kyung;Jin, Yong-Jae;Kim, Dong-Il
    • The Journal of Korean Obstetrics and Gynecology
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    • v.22 no.1
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    • pp.191-202
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    • 2009
  • Purpose: This research is to investigate the needling Depth for Deqi based onone's age, weight, and the level of obesity and the different Deqi sensation in Chung-wan and Kwan-wan. Methods: We took a research on Deqi for the 123 patients who visited a local Korean Medicine clinic at random. The variants were the age, the weight, thetotal fat rate, the waist-hip rate, BMI, the weight size, and the Sasang constitution. Result: Older patients need more depth of Deqi in Chung-wan and Kwan-wan compared to the younger ones. The higher the level of obesity(weight, total body fat rate, the waist-hip rate, BMI) goes up, the more Deqi in Chung-wan and Kwan-wan goes deeply. As the level of obesity goes down in the order of Taeeum-in, Soyang-in, Soeum-in, the depth of Deqi also decreases in Chung-wan and Kwan-wan. Deqi in Chung-wan is the feeling of pressure around the acu-point, and Deqi in Kwan-wan is the feeling that it spreads out to the upper, lower, the right, and the left side of the acu-point. Conclusion: In case of Needling Depth for Deqi on Chung-wan and Kwan-wan, that increases or decreases as the age, the level of obesity(the physique), and the Sasang constitution changes.

Analysis of Sports Injuries in Kendo (검도 운동에서 발생된 스포츠 손상의 분석)

  • Song, Hyun-Seok;Park, Sung-Jin;Han, Suk-Ku;Nah, Ki-Ho;Cheung, Hyung-Kook;Choi, Woo-Hyuk;Choi, Nam-Yong
    • Journal of Korean Orthopaedic Sports Medicine
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    • v.4 no.2
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    • pp.122-127
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    • 2005
  • Purpose: To study the mechanism of injuries or discomfort during kendo and to analyze the causes of injury, injured parts of body, treatments modalities, and degree of return to the pre-injury activity level. Materials and Methods: We studied ninety-eight kendo players who had played at three gymnasium of Korean Kumdo Association, were older than high-school age, had been playing kendo for more than six months, and had any pain or discomfort after playing kendo. We analyzed the questionnaire and interviewed the patients concerning the injured parts of body, symptoms, treatments. Results; The mean age was 30.2 years old, and the onset of symptoms was between two weeks and six months after starting the kendo. Many of them were injured during attacking(32.2%). The injuries of feet were increased on players who exercised for less than 1 year. Only fifty-nine players(60.2%) were treated within one month. Among them, thirty-eight percent were treated by oriental medicine or other departments and only thirty-six percent were treated by orthopaedic surgeons. The prevalence of injuries of the foot and ankle was highest(38.8%), and there were the wrist(13.1%), shoulder(11.9%), knee(11.9%) in order of prevalence. Fifty percents of them could return to the pre-injury activity level. Conclusion: The prevalence of injuries of the foot and ankle was highest(38.8%), and were increased on players who exercised for less than 1 year. Sixty percents of players were treated with any proper modalities, and only thirty-six percent were treated by orthopaedic surgeons.

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