• 제목/요약/키워드: 과학 교실

검색결과 1,590건 처리시간 0.025초

사람면역결핍바이러스감염증 치료 중 발생한 중대뇌동맥협착의 악화 및 재발성 뇌경색 (Recurrent Ischemic Strokes with Progression of Middle Cerebral Artery Stenosis during HIV Treatment)

  • 강종수;김민옥;이정진;박민원;김창헌;김영수;박기홍;강희영;최낙천;권오영;김수경
    • 대한신경과학회지
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    • 제36권4호
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    • pp.337-340
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    • 2018
  • Human immunodeficiency virus (HIV) infection can result in ischemic stroke via several mechanisms, including opportunistic infection, vasculopathy, cardioembolism, and coagulopathy. HIV-vasculopathy is related to endothelial dysfunction, stenosis and aneurysm formation, infectious vasculitis, dissection and accelerated atherosclerosis during highly active antiretroviral therapy (HAART). We represent a case of HIV infection manifested as an acute ischemic stroke attack. After 4 months during HAART, our patient experienced a recurrent ischemic stroke with progression of middle cerebral artery stenosis.

아토피피부염의 치료 (Treatment of Atopic Dermatitis)

  • 한태영;나찬호;이지현;김혜원;박창욱;서영준;손상욱;신민경;안지영;이양원;장용현;박영립;유박린
    • 대한피부과학회지
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    • 제56권10호
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    • pp.581-593
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    • 2018
  • Atopic dermatitis (AD) is a common, chronic, relapsing, inflammatory skin disease that affects both children and adults. AD is the cause of considerable morbidity including severe pruritus and impaired quality of life. Treatments for active disease include avoidance of triggering factors, barrier repair, topical medications including topical corticosteroids (TCs) and topical calcineurin inhibitors (TCIs), phototherapy, antibacterial agents, and systemic immunosuppressants including cyclosporine. Until recently, the only Food and Drug Administration (FDA)-approved systemic treatment options for patients with moderate-to-severe AD were steroids and cyclosporine. Systemic steroids are not recommended by current guidelines and are commonly associated with disease rebound. Instead, clinicians choose from several off-label immunosuppressants. In 2018, the Korean FDA approved dupilumab for adults with moderate-to-severe AD whose disease is not adequately controlled with topical therapies. The implementation of treatment guidelines for AD is challenging. Herein, we review the several treatment modalities for AD and recommend a treatment algorithm.