• Journal of Oriental Neuropsychiatry
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• v.15 no.2
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• pp.191-201
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• 2004

The purpose of this study was to evaluate the effects and limitations of cognitive & behavioral therapy that applied to the social phobia. In this case, a female patient, 25 old, who had been treated distantly by her friends, was trained to catch her dysfunctional belief and maladaptive automatic thoughts. In this training, we used homework and counselling for 2months. And we diagnosed her state as SimDamHeoGup(心膽虛怯), so we used acupuncture treatment and herbs, for example HaChulBoShimTang(夏朮補心湯) and GuiBiWonDamTang(歸脾溫膽湯). In result, she could recover social relationship slowly. Conclusionally, cognitive & behavioral therapy can be very effective methods to treat social phobia, because patients with social phobia have maladaptive automatic thoughts, based on dysfunctional beliefs like 'I'm infelicitous' or 'I'm ineffective'.

• Korean Journal of Psychosomatic Medicine
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• v.3 no.2
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• pp.139-146
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• 1995

Forty patients meeting DSM-III-H criteria for panic disorder and 51 normal controls were assessed with the Personality Diagnostic Questionnaire-Revised(PDQ-R), a self-rating scale designed to assess Axis II personality disorders and traits. Results replicated previous findings of a preponderance of dependent, avoidant, and histrionic features. But our result showed other features such as paranoid, schizotypal, borderline, and antisocial traits also. Patients were divided into two groups according to the severity of their personality traits(high or low). These groups were compared in various panic symptomatology and SCL-90-R. None of the specific symptom dimensions in panic disorder, i.e. panic, anxiety, agoraphobia, social impairment, or chronicity was different between groups. Rather, high personality trait groups were found to have significantly more symptomatology in SCR-90-R than low personality groups. Result indicated that patients exhibiting a greater number of personality traits were also significantly more symptomatic. The results suggested a possible link beteween panic disorder and personality disorder. And, general factors such as depression, social or interpersonal sensitivity might provide a much better explanation of personality disorders in panic patients.

• Journal of Dental Rehabilitation and Applied Science
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• v.27 no.4
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• pp.415-422
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• 2011

The study on correlation between the parents' character of orthodontic patients and patients cooperation. Although dentists have excellent skill and technique, patients' cooperation is always demanded. Patients' poor cooperation results in poor treatment result. Cooperation between psycho-social state of parents and patient's cooperation was studied. The parent's psychosocial state is evaluated with scl-90-r. The cooperation is measured by appointment time compliance, appliance taking rate, breakage of appliance, and fee paying. Parents' psychosocial contents are somatization, obsessive-compulsive, interpersonal sensitivity, depression, anxiety, hostility, phobic-anxiety, paranoid ideation, psychoticism, and additional item. Statistics was done by SPSS WINDOW version 12.0 program. The result showed no correlation between patients' cooperation and their parents' psychosocial state. There is no correlation between father's psychosocial state and patients' cooperation except psychoticism. There is no correlation between mother's psychosocial state and patients' cooperation. However, there was correlation among cooperation variables: appointment time compliance, appliance taking rate, breakage of appliance, cost paying. Appliance taking rate and cost paying showed positive correlation. Our findings suggest that patients' cooperation does not followed their parents' pychosocial state. Other combined factors should be considered like pychosocial state of patient and doctor-patient relationship.

• Journal of the korean academy of Pediatric Dentistry
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• v.33 no.4
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• pp.710-716
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• 2006

The purpose of this study is to evaluate the intravenous (IV) sedation technique with midazolam and ketamine for uncooperative dental child patients. Three child patients between the ages of 4.4 years and 5.6 years who required sedation for dental treatment were given midazolam and ketamine. Initial dosage was combined of $0.03{\sim}0.06mg/kg$ midazolam and 1.0mg/kg ketamine. Additional dosages of ketamine (0.33mg/kg) were given as needed to maintain deep sedation. Pulse rate, respiratory rate, blood pressure, oxygen saturation, adverse reactions, postoperative recovery and behavior were monitored with saturation pulse oximetry, ECG, NIBP and Cardiocap. In conclusion, the combination of midazolam and ketamine is efficacious in deep sedation for painful dental treatment. However, a significant drop in oxygen saturation was observed as a common adverse side effect. Therefore advanced airway management proficiency is required in order to achieve a successful IV sedation.

• Journal of Oral Medicine and Pain
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• v.38 no.2
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• pp.103-108
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• 2013

Pachyonychia congenita is a very rare group of an autosomal dominant genodermatosis caused by heterozygous mutations in the keratin genes. The clinical findings affect nail and toenails, soles, and oral mucosa, etc. The main symptoms include nail and toenail dystrophy, hyperkeratosis of hands and feet, follicular hyperkeratosis, oral leukokeratosis. Many therapeutic modalities have been used to treat skin lesion, including surgical and mechanical procedures, chemical agents, medications. Oral lesions but not usually require treatment, if the patient's discomfort occurs, symptomatic therapy is performed. In the patients accompanied by oral and skin lesions, clinician have to observe specific manifestations with dystrophy of the fingernails and toenails, plantar hyperkeratosis, oral leukokeratosis and tissue biopsy is required for diagnosis confirmed.

• Radiation Oncology Journal
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• v.17 no.3
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• pp.230-237
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• 1999

Purpose : To elucidate the effects of pentoxifylline and diltiazem on the late response of the salivary glands of the rat after irradiation. Materials and Methods : Sixteen Sprague-Dawley rats were divided into 4 groups : (a) irradiation alone (b) irradiation with pentixifylline (PTX) (c) irradiation with diltiazem (DTZ) (d) irradiation with both PTX and DTZ. Irradiation was given in a single fraction of 16 Gy using 4 MV photon energy through an anterior port encompassing the left side of the salivary gland leaving the right side of salivary gland as a control. PTX, 20 mg/kg and/or DTZ, 50 mg/kg were infused intraperitoneally before irradiation, Two rats from each group were sacrificed on the 10th week and the rest was sacrificed on the 16th week after irradiation. Histopathologic examinations were undertaken for each section and the proportion of vacuolated cells out of the total number of cells under light microscopic fields was calculated. The statistical significance in the difference of the proportion of the vacuolated cells among the experimental groups was evaluated by a $x^2$-test. Results : Irradiated salivary glands of the 10th week group revealed markedly increased number of vacuolated cells compared to those of unirradiated control. The proportion of vacuolated cells was significantly reduced in both the PTX group (p value=0.001) and the combined PTX and DTX group compared to those of irradiation alone group. The DTZ alone group did not reveal the significant reduction of vacuolated cells compared to those of irradiation alone group (p value, >0.05). The 16th week groups revealed similar findings to those of the 10th week group, but the degree of chronic inflammatory cell infiltrates and interstitial fibrosis was increased and the number of acinar cells was reduced compared to those of the 10th week group. Conclusions : PTX significantly reduced the late radiation response of salivary glands, but DTZ did not reduce the same degree as PTX did. Taking the positive results of this study into consideration, it seems reasonable to apply PTX into the clinical trial for the head and neck irradiation to reduce the late radiation sequelae of salivary glands in the near future. At the same time the further experiment to clarify the subcellar mechni는 involved in PTX should be preceded.

• Journal of Oriental Neuropsychiatry
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• v.25 no.2
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• pp.153-164
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• 2014

Objectives: In this case report, we will show the effectiveness of herbal medicine with neurofeedback treatment on social phobia. Methods: First, we diagnosed the patient by interview and questionnaire as having social phobia and suffering from anxiety, shaking and palpitation in public places and fear to meet new people. Beside, we examined the pattern of brainwaves by QEEG-8 system. Second, we treated the patient by herbal medicine with neurofeedback treatment for 4 months. Then we conducted new assessments by SCL-90-R, BDI, BAI and QEEG-8 system. Results: The patient's psychological and physiological symptoms were significantly improved. Conclusions: Herbal medicine with neurofeedback can be effective in the treatment of social phobia. Especially, it can be helpful to improve the patient's sensitivity to its physiological symptoms.

• Journal of the korean veterinary medical association
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• v.32 no.5
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• pp.317-327
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• 1996

소의 해면형 뇌증(Bovine Spongiform Encephalpathy; BSE)은 우리나라에서의 발생보고는 없으나, 우리에게 그리 생소한 질병만은 아니다. 저자중 한사람인 진 영 화 박사는 일찌기 소 해면형 뇌증의 발견 초창기인 1987년도에 UNDP 가축위생강화계획에 의하여 영국 중앙수의연구소(CVL)에 파견되어 소 해면형 뇌증의 진단병리 연구에 참여한 바 있으며, 강 영 배 박사는 전국 각 시도 가축위생시험소장을 인솔하여 영국 중앙수의연구소를 3차례 다녀온 바 있다. 본편에서는, 1991년 해외출장 기간 중 영국정부를 통하여 입수한, 새로운 질병 즉 소의 해면형 뇌증(Bovine Spongiform Encephalpathy)에 대한 Video tape 자료중, 'BSE 이야기 - 모든 합리적인 대책방안(MAFF V710)'과 'BSE 임상증예 5예 보고(MAFF V659)'를 기본으로하여 사진 또는 영문자료와 함께 소개하고자 한다. BSE의 잠복기는 2년 이상으로 매우 길며, 3-5세의 성우에서 다발한다. 주요 임상증상은, 정신상태, 정서 및 운동의 이상으로 특징지어 지는데, 광증과 침울 등 행동이상을 나타내며, 특히 후지파행, 비틀거림, 미끄러짐, 넘어짐 등의 보행이상을 나타낸다. 초기의 관찰사항으로는, 출입구 통과나 착유실 입실을 거부하는 등 불안 상태를 흔히 나타내는 것이다. 건드리거나 소리에 민감하게 반응하는 지각과민증, 경증의 보행실조, 발로차기, 동물이나 관리자에 대한 공격적 자세, 그리고 공포자세가 흔히 수반된다. 임상소견은 발병기간 중 일관되게 유지되며, 개체별로는 수주일부터 수개월간 지속된다. 젖소에서는 산유량이 떨어지며, 6개월내지 1년 정도 경과후 100$\%$ 폐사되는 것이 특징이다. 치료시도는 전혀 효과가 없다.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.7 no.1
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• pp.34-43
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• 1996

In adolescence, the symptoms of depression are more various and different from those of adult. Conduct behaviours are frequently represented in adolescent's depression. The patients who have the depression and conduct disorder are defined as depressive condor disorder in ICD-10. We hypothesized that there might be different parental rearing patterns between the patients with depression alone and the depressive conduct disorder. We applied children's depression inventory (CDI), parental rating form for conduct disorder based on DSM-III-R, and parental bonding instrument (PBI) to patients and normal control adolescent group. The results were as follows : 1) There were no significant differences in severity of depressive symptoms, maternal care, maternal overprotection, and paternal care. 2) Paternal overprotection showed significant higher scores in depressive conduct disorder group than depression group and normal control group. 3) There were positive correlations in the severity of depressive symptoms and behavior problems in all subjects. 4) There were no correlations in maternal care and overprotecion with conduct problems, but with depressive symptoms in all subject. 4) There were no correlations in paternal care with conduct problems and depressive symptoms in all subjects. 5) There were significant correlations in patienral overprotective, intrusive attitudes with conduct problems, not with depressive symptoms in all subjects.

• 한국HCI학회:학술대회논문집
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• 2006.02a
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• pp.1099-1106
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• 2006

정신질환자들은 자기감정을 표현하는 능력의 결손을 보인다. 이러한 자기 감정표현기술은 정신질환자들을 위한 사회기술훈련 (Social Skill Training) 과정 중 하나로서 정상적인 사회생활로의 복귀를 위해 반드시 필요하다. 지금까지의 자기감정표현 훈련 및 평가 방법은 치료자 능력의 차이에 따른 주관적 판단이 개입될 수 있다는 문제점을 가지고 있다. 가상현실 (Virtual Reality)은 컴퓨터를 이용한 최신의 방법으로, 최근 자폐증이나 공포증 등의 정신질환 분야에도 적용되고 있다. VR 을 사용하면 상호작용을 할 수 있고, 다양한 환경과 자극을 제시할 수 있으며, 3 차원 랜더링을 통해 몰입감을 제공할 수 있다. 또한 저장된 파라미터들을 바탕으로 객관적 판단을 할 수 있는 기준을 제시할 수 있으며, 안전하고 시간과 공간적 제약이 적은 환경 내에서 과제를 수행할 수 있다. 이에 본 연구에서는 자기감정표현기술의 객관적 평가를 위한 가상현실 시스템을 개발하고 정신분열증 환자와 정상인을 대상으로 실험을 진행하였다. 가상현실은 크게 긍정적 상황과 부정적 상황으로 이루어 지는데 집, 카페, 빵집, 길거리 등 다양한 환경에서 가족, 친구, 직장동료 등의 아바타가 실험 참가자에게 말을 건네고 참가자는 적절한 시기에 자신의 감정표현을 하도록 구성하였다. 실험을 하면서 정서 (긍정적 상황 Vs. 부정적 상황)에 따른 자기감정표현에 대한 파라미터로서 아바타가 말하는 동안 참가자가 아바타의 말에 주목을 하는 정도 (아바타가 말하는 동안 참가자가 아바타의 얼굴을 쳐다보는 시간)와 자기감정을 표현을 하는 시간 (아바타의 말이 끝난 후 감정표현을 시작하는 시간과 감정표현시간)과 상대방 아바타를 주목하는 정도 (참가자가 자기감정을 표현하는 중 아바타를 쳐다보는 시간) 등을 측정하였다. 측정결과 정상인이 정신분열병 환자에 비해 아바타를 주목하는 시간이나 자기감정표현을 하는 시간이 더 긴 경향이 있었다. 또한 부정적 상황에서 정신분열병 환자와 정상인 모두가 긍정적 상황에 비해 말하는 아바타에 더 잘 주목하였고, 자기감정을 표현하는 시간도 더 긴 것을 확인 하였다. 따라서 본 연구에서 도출된 파라미터는 실험 참가자의 자기감정표현의 정도를 객관적으로 나타낼 수 있을 것으로 생각된다. 또한 정신분열병 환자의 자기 감정표현능력을 측정하는 도구로 사용될 수 있을 것으로 생각된다.