• Korean Journal of Poultry Science
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• v.16 no.4
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• pp.219-232
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• 1989

The present study was done to investigate the mechanism of Pancreatic digestive enzyme secretion in response to dietary components in chicks. A simplefied pancreatic juice collection method, useful for a short-term experiment, was developed. By wing vein injection, it was shown that the increased trypsinogen and chymotrypsinogen, while neither other single amino acids nor glucose affected the secretion of enzymes, amylase, trypsinogen and chymotrypsinogen. Cholecystokinin (CCK) had an immediate effect on pancreatic enzyme secretion and this response was in a dose dependent fashion. The injection of CCK seemed to have selective stimulation favoring the secretion of chymotrypsinosen followed by amylase and trypsinogen. Simultaneous injection of single amino acid with CCK increased digestive enzyme secretion to various extents depending on the kind of amino acids whereas the injection of glucose with CCK did not affect when compared with that of CCK'alone. By varying doses, synergetic action of CCK plus amino acid on the secretion of pancreatic digestive enzymes was observed at 0.5mM for Val and 5mM for Arg. A further attempt was made to examine the effect of combined administration of amino acids with CCK on pancreatic enzyme secretion. The injected substances were an AAs mixture and combination of selected amino acids, i.e. Thr＋Phe＋Ile, Thr＋Phe. Thr＋Ile or Phe＋Ile. When increases in enzyme outputs for the first 30 min were compared , it was shown that the responses of three enzymes, amylase, trypsinogen and chymotrypsinogen, brought about by the administration of the AAs mixture was almost entirely accounted for by the combined injection of Thr＋Phe. Thus, it was well demonstrated that CCK and amino acids had a synergetic action on the secretion of a specific pancreatic digestive enzyme depending on a kind of amino acid injected.

• Journal of the Korean Geotechnical Society
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• v.15 no.5
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• pp.229-240
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• 1999

The groundwater flow and grout flow in individual rock joint and jointed rock mass are studied using various methods of analysis such as (i) the finite difference method, (ii) channel network analysis and (iii) joint network analysis. The flow behaviour is investigated in two distinguishable scales of observation: one for a rough joint of a laboratory scale having variable aperture, and the other for field- scale rock masses having three sets of intermittent joints. In the former case, the aperture-dependent channel flow is identified for both water and grout flows. The comparison of the flow rate in a rough joint is made between the finite difference analysis and existing analytical solution. In the latter case, the effects of increasing number of joints on the groundwater inflow into a circular opening of various diameters are analyzed using both the joint network method and Goodman's analytic solution. Comparisons are made between the two methods. The boundary effects in the joint network method are discussed. The inhomogeneity of joint network and its impacts on the groundwater inflow are also discussed.

• Korean Journal of Construction Engineering and Management
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• v.23 no.5
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• pp.23-33
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• 2022

Cracks, which account for the largest proportion of defect lawsuits in apartment buildings, are not clear on the criteria for defect determination, so judgments about defects are mixed. Interlayer cracks, which account for most of the crack defect judgment amount, tend to be judged as defects regardless of the crack width or condition, and repair methods are mostly set uniformly. This starts from the problem that the standards of the Ministry of Land, Infrastructure and Transport and the Construction Appraisal Practice, which the courts use as standards, do not match. It is necessary to establish a defect determination standard that can be applied to all stakeholders through the amendment of laws and the revision of the Court Appraisal Practice. In addition, it is necessary to apply the crack repair method according to the width and condition of the interlayer crack. If the defect determination and the application of the repair method for cracks are rationalized, it could serve as an opportunity to change the current trend of defect disputes that rely only on litigation.

• Journal of the Korean Chemical Society
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• v.67 no.1
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• pp.19-27
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• 2023

During the past few decades, toxicity science is shifting from observative to predictive science. New approach methodologies (NAMs), including in chemico, in silico, in vitro approach, gain attention to reduce, refine, replace the whole animal toxicity testing. However, actual acceptances of NAMs in regulatory decision-making have been limited due to low confidence. To address the current constraints, Accelerating the Pace of Chemical Risk Assessment (APCRA) initiative conducted several case studies and presented the perspectives of next generation risk assessment (NGRA). In this review, we suggested a concept and perspectives of NGRA through analysis on APCRA case studies.

• Journal of Technology Innovation
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• v.25 no.3
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• pp.83-113
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• 2017

This paper constructs panel data of inventors listed on patents applied for the KIPO during 1991-2005 and analyzes the effects of network characteristics on inventor productivity. The findings are as follows: ⅰ) Strong ties within a network have positive effects on inventor productivity. ⅱ) An inventor with high centrality shows high producitivity. ⅲ) Technological diversity of a network enhances inventor productivity. ⅳ) An inventor belonging to a network of good quality shows higher productivity. ⅴ) Network size is positively related with inventor producitvity. ⅵ) A lone inventor shows the highest productivity among types of inventors, and a co-inventor with the experience of standalone invention is more productive compared to an inventor with only the experience of co-invention. ⅶ) The productivity effects of network variables differ across regions. ⅷ) Differences among regions do not decrease though geographical boundaries become less important.

• Journal of The Korean Association For Science Education
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• v.23 no.1
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• pp.100-116
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• 2003

The purpose of this paper is to investigate the objectivity of scientific knowledge, focusing on Michael Polanyi's epistemology. The objectivity of scientific knowledge could be examined in epistemological and ontological view. The former relates to the rationality, but the latter to the reality. Since the middle of 20th century science philosophers have debated about the objectivity of scientific knowledge. Their opinions are divided three parts by the criteria of objectivity in relation to the rationality. Exactly Objectivism approves the rationality of scientific knowledge, and Falsificationism accepts the panial rationality, but Relativism denies any rationality. In this paper, we will study the objectivity of knowledge in relation to the subjectivity, especially throughout the theory of Kant, Kierkegaard and Wang Yang-ming. Experienced good scientist Polanyi(1946; 1958) have ever suggested the new epistemology as the name of 'personal knowledge'. He argues that scientific knowledge is personal by faith, trust, passions, tacit understanding, method rules embodied in practice. Some implications were discussed for science education from the view of Polanyi. The first holds that science class needs human voice throughout the personal commitment. The second holds that intellectual passions should he recovered. The third holds that the teacher should act like real scientist. Finally, the theory of science education should be established for ourselves.

• 한국방재학회:학술대회논문집
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• 2011.02a
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• pp.191-191
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• 2011

최근 빗물이 우리가 앞으로 이용할 수 있는 수자원이라는 사회적인 인식의 변화와 함께 빗물이용이 더욱 요구되어졌다. 특히 빗물의 이용 저류 침투를 목적으로 하는 우수 관리에 대한 관심이 증가하면서 빗물이용시설의 설치, 운용의 필요성이 대두되고 있다. 이에 반해 화재발생은 해마다 증가하고 있으며, 화재 증가는 소방력 활동의 증가로 귀결되는데 현장활동 인력과 장비 그리고 화재를 진압하는데 사용되는 소방용수 증가를 의미한다. 따라서 본 연구는 빗물을 소방용수로 즉, 화재진압시 활용 가능성과 수자원 절약, 화재 사각지역 해소 측면을 살펴보기 위해서 통계분석, 현장조사, 기존 빗물이용시설 및 향후 완공 예정인 우수유출저감시설 활용과 소방용수 미설치 지역과 소방관서 옥상에 빗물이용시설 설치 방안을 제시하였으며, 그에 따른 공공서비스 확대와 경제성 분석을 통하여 다음과 같은 연구결과를 도출하였다. 첫째, 기존 빗물이용시설을 소방용수로 적극적으로 활용해야 한다. 빗물이용시설의 주 용도로 조경용수, 청소용수, 소방용수로 나눌 수 있는데 이수 측면에서 화재가 발생하지 않으면 소방용수로서 이용이 거의 없는 실정이다. 이는 해당 건물관계자나 소방대원들이 빗물이용시설을 인식을 못하고, 사용과 접근성 불편으로 상수도와 연결된 소화전에 의존하는 경우가 많다고 본다. 둘째, 상수도시설이 없는 지역은 빗물이용으로 소방용수를 확보해야 한다. 섬, 산간, 고지대, 농촌지역 등 상수도 서비스를 공급받지 못하는 지역은 화재발생시 수원확보곤란으로 인명과 재산피해의 증가요인으로 작용할 수 있다. 공공서비스 확대차원에서 화재 사각지역을 해소하기 위해 지붕면을 이용한 각 가정마다 또는 공동 빗물저장소와 지형의 비탈면을 이용한 빗물이용시설 설치로 소방용수 확보의 필요성을 확인했다. 셋째, 소방관서 신설시 빗물이용시설을 도입하여 설치한다. 화재통계와 현장조사를 통하여 소방차 출동대기부터 화재진압까지 많은 양의 물이 사용되는 것으로 파악되었다. 대부분 먹는 물 즉, 상수도를 이용한다는 점에서 수자원 절약과 화재진압에 사용된 물은 재생 불가능이라는 환경보전 측면에서 빗물이용으로 해답을 찾아본다. 따라서 빗물을 많이 저장할 수 있도록 옥상, 부지 등 집수면적을 확대하고 이에 적합한 저류시설을 갖춘 빗물이용시설을 설치한다. 끝으로 신속하고 효율적인 화재진압이 중요한 만큼 빗물을 소방용수로 활용하고자 할 때는 언제 어디에서나 현장 접근성, 사용 편리성, 충분한 수량을 고려해야한다.

• Annual Conference on Human and Language Technology
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• 1997.10a
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• pp.283-287
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• 1997

본 논문에서는 당 연구소 주관으로 연구개발정보센터(KORDIC), 서울대와 공동으로 개발중인 한영 기계번역 시스템, '에서로/KE'의 prototype system을 설명한다. 에서로/KE는 KORDIC에서 한국어 형태소 분석기와 Tagger를 개발하고, 서울대에서 한국어 구문해석기와 한영 변환기를 개발하고, SERI에서 영어 구문 생성기와 영어 형태소 생성기를 개발한다. 한국어 Tagger는 HMM에 기반하여 제작되었으며 sample 200문장에 대해 98.9%의 정확률을 보인다. 한국어 구문 해석기는 의존 문법에 기반하여 CYK 알고리즘을 사용하여 제작되었으며 중의성 해결을 위해 29개의 최적 parse 선택 규칙이 구현되어 있다. 한영 변환기는 collocation과 idiom에 기반하여 한영 변환을 수행한다. 영어 구문 생성기는 Tree 변환 언어인 GWL(Grammar Writing Language)를 사용하여 작성되었으며, 영어 형태소 생성기는 최종적으로 자연스러운 영어 표층문을 생성한다. 에서로/KE는 현재 1차년도 Prototype system이 Unix 환경에서 구현되어 있으며, 현재 각 모듈별 성능 개선과 대량 사전 구축을 통해 상용화될 예정이다.

• Journal of the Korean Society for Library and Information Science
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• v.46 no.3
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• pp.233-250
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• 2012

The purpose of this study is to assess the development, current states, and problems of MEDLIS document delivery service. With the analysis of MEDLIS transaction data from 2001 to 2011, we identified continuous usage decrease, unbalanced contribution by type of institution, high dependence on back issues, use differences among subfields of medicine, relatively low success rate, and various reasons for failure. Based on the results, recommendations for the maintenance of union catalog database, technical support for search capability enhancements, establishment of back issue archiving policy, user training and publicity, and membership expansion are suggested to promote the service.

• Proceedings of the Korean Institute Of Construction Engineering and Management
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• autumn
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• pp.244-247
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• 2002

The pile foundations have been chosen more frequently as the comprehensive development of the country progressed, especially where the ground conditions are not suitable for the construction and the dimension and the length of the piles utilized becomes larger and longer. The purpose of this study suggests the improvement method of construction management for PHC pile in an apartment house. To do This, We analyzed about current process and provided improved Process with IDEF method. And, The objectives of this research is to propose the means to solve the current problems and management factors from the results of the investigation.