• 나누는사람들
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• s.1
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• pp.1-4
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• 1996

• Journal of the Korean Arthroscopy Society
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• v.10 no.2
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• pp.199-202
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• 2006

The effects of acute hematogenous osteomyelitis vary with a patient's age because of the differences in the blood supply and structure of the bone. In children older than 2 years of age, this process results in extensive abscess formation when both the endosteal and periosteal blood supply are destroyed. Thorough drainage of abscess cavity and removal of all dead or necrotic material are not always possible although large skin incision is made along the abscess. Authors successfully managed acute osteomyelitis of the tibia with extensive large abscess in a 11 year-old female, using minimal incisions and 4-mm endoscope.

• Pediatric Infection and Vaccine
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• v.9 no.2
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• pp.236-240
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• 2002

Vertebral osteomyelitis represents only 1% to 2% of osteomyelitis and may pose a diagnostic conundrum, with disastrous consequences if diagnosis and therapy are delayed. We report a neonate with the unique association of vertebral osteomyelitis and MRSA infection. A 1-month-old boy was admitted to the hospital for evaluation of high fever and decreased oral intake. He was born at 34 wks, and his birth weight was 1.6 kg. We founded MRSA on his blood culture. Magnetic resonance imaging study showed findings of T7-T8 vertebral osteomyelitis. With 8 weeks of intravenous vancomycin treatment, the patient improved clinically and radiologically.

• Applied Microscopy
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• v.32 no.4
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• pp.385-398
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• 2002

The purpose of the present study is to investigate whether stromal cells supporting specific microenvironment for hematopoiesis of bone marrow are affected by toxicants and therapeutic drugs such as antibiotics and anticancer drugs and whether laminin-1 is associated with such effects. SD rats were intraperitoneally injected with 75 mg/kg of cyclophosphamide which is widely used to treat infant's solid tumor, leukemia and myeloma and sacrificed after 3 days, 1 week, 3 weeks or 5 weeks of injection. The bone marrow extracted and paraffin-sectioned was analyzed using immunohistochemical staining. A part of tissues was subjected to electron microscopy following reaction with rabbit anti-laminin antibody, biotinylated goat anti-rabbit IgG conjugated with 12 nm gold particles, and staining with uranyl acetate. 1. The bone marrow tissue at day 3 post injection with cyclophosphamide displayed dilated venous sinus, partial necrotic death, and decreased number of hematopoietic cells. Laminin-1 was intensively stained in the reticular and adipose tissues. 2. Up to 5 weeks post injection, laminin-1 was stained at a low level in the stromal tissue of bone marrow and the number of hematopoietic cell was increased. 3. Deposition of the gold particle which represents laminin-1 expression was observed at the highest level in the stromal cells of bone marrow obtained 3 days after injection, and decreased after 1 to 5 weeks. These results suggest that stromal cells which play a role in supporting microenvironment for bone marrow hematopoiesis augment induction of laminin-1 expression and activation upon administration of cyclophosphamide.

• Proceedings of the Korean Information Science Society Conference
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• 2000.04b
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• pp.505-507
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• 2000

현재 백혈병 진단에서 사용중인 방법은 골수영상을 획득하고 이를 관찰하여 비정상의 백혈구의 형태, 백혈구 핵의 크기와 추출된 골수에서의 백혈구가 차지하는 비율을 이용하여 진단하고 있다. 비정상적인 모양을 띠고 있는 백혈구의 검출은 백혈병 진단에 있어 중요한 정보로 사용된다. 백혈구의 이상 형태중 다수의 구멍이 있는 백혈구는 검출하기 위해 골수영상에서 백혈구 영역을 추출하고 이에 대해 UNL transform을 이용하여 모양 특징을추출하였다. UNL Fourier transform은 원영상의 이동(translation), 회전(rotation), 확대/축소(scale)에 대해 불변인 성질을 지니므로 이를 이용해 백혈구의 모양 특징을 추출하고 유사도 검색을 통해 비정상의 백혈구를 검출하였다.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1994.04a
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• pp.207-207
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• 1994

I) 지금까지 만성골수성백혈병의 치료법으로서 골수이식이나 인터페론의 투여등이 시행되어왔으며 백혈병세포에서 Interleukin-1$\beta$(이하 IL-1$\beta$)이 자율적으로 생성됨이 보고 되어 이러한 질병의 진행에 IL-1$\beta$의 활성증가가 관련될것이라는 견해가 대두되어 왔다. 최근 단핵구성백혈병 환자의 소변에서 분리된 IL-1수용체 길항제(1L-1 receptor antagonist: IL-lRA)가 clonig되었고 인터페론치료에 저항하는 환자들의 치료에 IL-1RA 가 이용될수 있을것이라는 견해가 있다. 따라서 본 연구는 유전공학연구소가 분리 정제한 IL-1RA가 만성골수백혈병 환자로부터 유래한 K562세포주의 증식에 미치는 영향을 평가하고 알파인터페론과의 병용투여시의 상호작용에 관해 검토하였다.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.1 no.2
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• pp.97-104
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• 1968

Some considerations were made concerning the variation in the number of vertebrae (except urostyle) of anchovies sampled from the south coast of Korea, mainly off the city of Chungmu. The some seasonal difference was evinced in the mean value of vertebrae of small sized fish only, and no other significant differences were observed such as for locality or fishing gears. It was concluded that the anchovies from the south coast of Korea might be devided into spring and summer hatching populations and that the seasonal variation in the number of vertebrae might be caused by the difference of water temperature during the spawning season.

• Journal of the Korean Arthroscopy Society
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• v.13 no.1
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• pp.68-71
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• 2009

Subacute osteomyelitis of the patella is a very rare condition and its diagnosis is delayed because of its rarity and variable presentation. This is a report of a case of osteomyelitis of the patella in an adult.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1981.05a
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• pp.13.1-13
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• 1981

Acute osteomyelitis of the maxilla with orbital cellulitis is occasionally seen secondary to a buccal infection, dental infection or necrotic process of the maxillary antrum. A case of acute osteomyelitis of the maxilla with orbital cellulitis in 5 years old boy has recently been experienced and cured by immediate incision and drainage combined with adequate antibiotics therapy. This paper was attempted to report the case with a brief review of reference.

• The Journal of the Korean bone and joint tumor society
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• v.15 no.1
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• pp.75-80
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• 2009

Extramedullary plasmacytoma is extremely rare, constitute 3 to 5 % of plasma cell malignancies and commonly occur in the upper aerodigestive tract. Several case studies of extramedullary plasmacytoma occurring in unusual location are reported; stomach, bladder, central nervous system, breast, thyroid, testis, salivary gland and skin. Here, we present a case of an extramedullary plasmacytoma of the right gluteus maximus muscle in a 49-year-old man.