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Development of LC-MS/MS analytical methods for metalaxyl in Atractylodes macrocephala Koidzumi and Achyranthes japonica Nakai (LC-MS/MS를 이용한 생약 백출 및 우슬 중 Metalaxyl 잔류분석법 개발)

  • Yun, Myung-Sub;Yang, Seung-Hyun;Choi, Hoon
    • Journal of Applied Biological Chemistry
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    • v.65 no.1
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    • pp.17-21
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    • 2022
  • A new rapid and simple method for metalaxyl in Atractylodes macrocephala Koidzumi and Achyranthes japonica Nakai has been developed and validated. This study was conducted to develop a method for analyzing metalaxyl by a method based on QuEChERS using liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS). Samples were extracted with acetonitrile and purified using amino-propyl (NH2) Solid Phase Extraction cartridge. The method limit of quantitation (MLOQ) was 0.01 mg/kg. The linearity of matrix-matched calibration curve (r2) was ≥0.99 at the calibration range of 0.001-0.05 mg/kg. For recovery test, Atractylodes macrocephala Koidzumi or Achyranthes japonica Nakai was treated with standard solutions at MLOQ and 10MLOQ levels. Recovery rates were in the range of 88.1-109.1% with <5.5% coefficient of variation. This established analytical method was fully validated. Based on these results, it can contribute to improving the safety of residual pesticides in Atractylodes macrocephala Koidzumi and Achyranthes japonica Nakai.

Tunnel Reverse Engineering Using Terrestrial LiDAR (지상LiDAR를 이용한 터널의 Reverse Engineering)

  • Cho, Hyung Sig;Sohn, Hong Gyoo;Kim, Jong Suk;Lee, Suk Kun
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.28 no.6D
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    • pp.931-936
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    • 2008
  • Surveying by using terrestrial LiDAR(Light Detection And Ranging) is more rapid than by using total station which enables tunnel section profile surveying to be done in suitable time and minimize centerline error, occurrence of overcut and undercut. Therefore, utilization of terrestrial LiDAR has increased more and more in section profile survey and measurement field Moreover, studies of terrestrial LiDAR for accurate and efficient utilization is now ongoing vigorously. Average end area formula, which was generally used to calculate overcut and undercut, was compared with existing methods such as total station survey and photogrammetry. However, there are no criteria of spacing distance for calculating overcut and undercut through terrestrial LiDAR surveying which can acquire 3D information of whole tunnel. This research performed reverse engineering to decide optimal spacing distance when surveying tunnel section profile by comparing whole tunnel volume and tunnel volume in difference spacing distance. This result was utilized to produce CAD drawing for the test tunnel site where there is no design drawings. In addition to this, efficiency of LiDAR and accuracy of CAD drawing was compared with targetless total station surveying of tunnel section profile. Finally, error analysis of target coordinate's accuracy and incidence angle was done in order to verify the accuracy of terrestrial LiDAR technology.

Development of a Grid-based Daily Watershed Runoff Model and the Evaluation of Its Applicability (분포형 유역 일유출 모형의 개발 및 적용성 검토)

  • Hong, Woo-Yong;Park, Geun-Ae;Jeong, In-Kyun;Kim, Seong-Joon
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.30 no.5B
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    • pp.459-469
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    • 2010
  • This study is to develop a grid-based daily runoff model considering seasonal vegetation canopy condition. The model simulates the temporal and spatial variation of runoff components (surface, interflow, and baseflow), evapotranspiration (ET) and soil moisture contents of each grid element. The model is composed of three main modules of runoff, ET, and soil moisture. The total runoff was simulated by using soil water storage capacity of the day, and was allocated by introducing recession curves of each runoff component. The ET was calculated by Penman-Monteith method considering MODIS leaf area index (LAI). The daily soil moisture was routed by soil water balance equation. The model was evaluated for 930 $km^2$ Yongdam watershed. The model uses 1 km spatial data on landuse, soil, boundary, MODIS LAI. The daily weather data was built using IDW method (2000-2008). Model calibration was carried out to compare with the observed streamflow at the watershed outlet. The Nash-Sutcliffe model efficiency was 0.78~0.93. The watershed soil moisture was sensitive to precipitation and soil texture, consequently affected the streamflow, and the evapotranspiration responded to landuse type.

An Improved Reliability-Based Design Optimization using Moving Least Squares Approximation (이동최소자승근사법을 이용한 개선된 신뢰도 기반 최적설계)

  • Kang, Soo-Chang;Koh, Hyun-Moo
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.29 no.1A
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    • pp.45-52
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    • 2009
  • In conventional structural design, deterministic optimization which satisfies codified constraints is performed to ensure safety and maximize economical efficiency. However, uncertainties are inevitable due to the stochastic nature of structural materials and applied loads. Thus, deterministic optimization without considering these uncertainties could lead to unreliable design. Recently, there has been much research in reliability-based design optimization (RBDO) taking into consideration both the reliability and optimization. RBDO involves the evaluation of probabilistic constraint that can be estimated using the RIA (Reliability Index Approach) and the PMA(Performance Measure Approach). It is generally known that PMA is more stable and efficient than RIA. Despite the significant advancement in PMA, RBDO still requires large computation time for large-scale applications. In this paper, A new reliability-based design optimization (RBDO) method is presented to achieve the more stable and efficient algorithm. The idea of the new method is to integrate a response surface method (RSM) with PMA. For the approximation of a limit state equation, the moving least squares (MLS) method is used. Through a mathematical example and ten-bar truss problem, the proposed method shows better convergence and efficiency than other approaches.

Modeling for Egg Price Prediction by Using Machine Learning (기계학습을 활용한 계란가격 예측 모델링)

  • Cho, Hohyun;Lee, Daekyeom;Chae, Yeonghun;Chang, Dongil
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2022.05a
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    • pp.15-17
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    • 2022
  • In the aftermath of the avian influenza that occurred from the second half of 2020 to the beginning of 2021, 17.8 million laying hens were slaughtered. Although the government invested more than 100 billion won for egg imports as a measure to stabilize prices, the effort was not that easy. The sharp volatility of egg prices negatively affected both consumers and poultry farmers, so measures were needed to stabilize egg prices. To this end, the egg prices were successfully predicted in this study by using the analysis algorithm of a machine learning regression. For price prediction, a total of 8 independent variables, including monthly broiler chicken production statistics for 2012-2021 of the Korean Poultry Association and the slaughter performance of the national statistics portal (kosis), have been selected to be used. The Root Mean Square Error (RMSE), which indicates the difference between the predicted price and the actual price, is at the level of 103 (won), which can be interpreted as explaining the egg prices relatively well predicted. Accurate prediction of egg prices lead to flexible adjustment of egg production weeks for laying hens, which can help decision-making about stocking of laying hens. This result is expected to help secure egg price stability.

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A Study on the Application of the Price Prediction of Construction Materials through the Improvement of Data Refactor Techniques (Data Refactor 기법의 개선을 통한 건설원자재 가격 예측 적용성 연구)

  • Lee, Woo-Yang;Lee, Dong-Eun;Kim, Byung-Soo
    • Korean Journal of Construction Engineering and Management
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    • v.24 no.6
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    • pp.66-73
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    • 2023
  • The construction industry suffers losses due to failures in demand forecasting due to price fluctuations in construction raw materials, increased user costs due to project cost changes, and lack of forecasting system. Accordingly, it is necessary to improve the accuracy of construction raw material price forecasting. This study aims to predict the price of construction raw materials and verify applicability through the improvement of the Data Refactor technique. In order to improve the accuracy of price prediction of construction raw materials, the existing data refactor classification of low and high frequency and ARIMAX utilization method was improved to frequency-oriented and ARIMA method utilization, so that short-term (3 months in the future) six items such as construction raw materials lumber and cement were improved. ), mid-term (6 months in the future), and long-term (12 months in the future) price forecasts. As a result of the analysis, the predicted value based on the improved Data Refactor technique reduced the error and expanded the variability. Therefore, it is expected that the budget can be managed effectively by predicting the price of construction raw materials more accurately through the Data Refactor technique proposed in this study.

Improvement of Basis-Screening-Based Dynamic Kriging Model Using Penalized Maximum Likelihood Estimation (페널티 적용 최대 우도 평가를 통한 기저 스크리닝 기반 크리깅 모델 개선)

  • Min-Geun Kim;Jaeseung Kim;Jeongwoo Han;Geun-Ho Lee
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.36 no.6
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    • pp.391-398
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    • 2023
  • In this paper, a penalized maximum likelihood estimation (PMLE) method that applies a penalty to increase the accuracy of a basis-screening-based Kriging model (BSKM) is introduced. The maximum order and set of basis functions used in the BSKM are determined according to their importance. In this regard, the cross-validation error (CVE) for the basis functions is employed as an indicator of importance. When constructing the Kriging model (KM), the maximum order of basis functions is determined, the importance of each basis function is evaluated according to the corresponding maximum order, and finally the optimal set of basis functions is determined. This optimal set is created by adding basis functions one by one in order of importance until the CVE of the KM is minimized. In this process, the KM must be generated repeatedly. Simultaneously, hyper-parameters representing correlations between datasets must be calculated through the maximum likelihood evaluation method. Given that the optimal set of basis functions depends on such hyper-parameters, it has a significant impact on the accuracy of the KM. The PMLE method is applied to accurately calculate hyper-parameters. It was confirmed that the accuracy of a BSKM can be improved by applying it to Branin-Hoo problem.

Restoration of Missing Data in Satellite-Observed Sea Surface Temperature using Deep Learning Techniques (딥러닝 기법을 활용한 위성 관측 해수면 온도 자료의 결측부 복원에 관한 연구)

  • Won-Been Park;Heung-Bae Choi;Myeong-Soo Han;Ho-Sik Um;Yong-Sik Song
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.29 no.6
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    • pp.536-542
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    • 2023
  • Satellites represent cutting-edge technology, of ering significant advantages in spatial and temporal observations. National agencies worldwide harness satellite data to respond to marine accidents and analyze ocean fluctuations effectively. However, challenges arise with high-resolution satellite-based sea surface temperature data (Operational Sea Surface Temperature and Sea Ice Analysis, OSTIA), where gaps or empty areas may occur due to satellite instrumentation, geographical errors, and cloud cover. These issues can take several hours to rectify. This study addressed the issue of missing OSTIA data by employing LaMa, the latest deep learning-based algorithm. We evaluated its performance by comparing it to three existing image processing techniques. The results of this evaluation, using the coefficient of determination (R2) and mean absolute error (MAE) values, demonstrated the superior performance of the LaMa algorithm. It consistently achieved R2 values of 0.9 or higher and kept MAE values under 0.5 ℃ or less. This outperformed the traditional methods, including bilinear interpolation, bicubic interpolation, and DeepFill v1 techniques. We plan to evaluate the feasibility of integrating the LaMa technique into an operational satellite data provision system.

Analysis of the long-term equilibrium relationship of factors affecting the volatility of the drybulk shipping market (건화물선 해운시장의 변동성에 영향을 미치는 요인들의 장기적 균형관계 분석)

  • Lee, Choong-Ho;Park, Keun-Sik
    • Journal of Korea Port Economic Association
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    • v.39 no.2
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    • pp.41-57
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    • 2023
  • The drybulk shipping market has high freight rate volatility in the chartering market and various and complex factors affecting the market. In the unstable economic situation caused by the COVID-19 pandemic in 2020, the BDI plunged due to a decrease in trade volume, but turned from the end of 2020 and maintained a booming period until the end of 2022. The main reason for the market change is the decrease in the available fleet that can actually be operated for cargo transport due to port congestion by the COVID-19 pandemic, regardless of the fleet and trade volume volatility that have affected the drybulk shipping market in the past. A decrease in the actual usable fleet due to vessel waiting at port by congestion led to freight increase, and the freight increase in charting market led to an increase in second-hand ship and new-building ship price in long-term equilibrium relationship. In the past, the drybulk shipping market was determined by the volatility of fleet and trade volume. but, in the future, available fleet volume volatility by pandemics, environmental regulations and climate will be the important factors affecting BDI. To response to the IMO carbon emission reduction in 2023, it is expected that ship speed will be slowed down and more ships are expected to be needed to transport the same trade volume. This slowdown is expected to have an impact on drybulk shipping market, such as a increase in freight and second-hand ship and new-building ship price due to a decrease in available fleet volume.

HRTF Interpolation Using a Spherical Head Model (원형 머리 모델을 이용한 머리 전달 함수의 보간)

  • Lee, Ki-Seung;Lee, Seok-Pil
    • The Journal of the Acoustical Society of Korea
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    • v.27 no.7
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    • pp.333-341
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    • 2008
  • In this paper, a new interpolation model for the head related transfer function (HRTF) was proposed. In the method herein, we assume that the impulse response of the HRTF for each azimuth angle is given by linear interpolation of the time-delayed neighboring impulse responses of HRTFs. The time delay of the HRTF for each azimuth angle is given by sum of the sound wave propagation time from the ears to the sound source, which can be estimated by using azimuth angle, the physical shape of the underlying head and the distance between the head and sound source, and the refinement time yielding the minimum mean square error. Moreover, in the proposed model, the interpolation intervals were not fixed but varied, which were determined by minimizing the total number of HRTFs while the synthesized signals have no perceptual difference from the original signals in terms of sound location. To validate the usefulness of the proposed interpolation model, the proposed model was applied to the several HRTFs that were obtained from one dummy-head and three human heads. We used the HRTFs that have 5 degree azimuth angle resolution at 0 degree elevation (horizontal plane). The experimental results showed that using only $30\sim40%$ of the original HRTFs were sufficient for producing the signals that have no audible differences from the original ones in terms of sound location.