• Journal of Food Hygiene and Safety
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• v.31 no.4
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• pp.294-298
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• 2016

Natural products are attractive as the source of new drug development. Especially, numerous unknown marine bioresources are an object of attention because the ocean occupies three fourth of the earth. Survival of marine bioresources in extreme environment may induce the production of biological active compounds. As previous study, we examined over 40 specimens of marine sponges collected from Micronesia and screened their anti-proliferative activities in various cancer cell lines. Among them, we investigated Coscinoderma sp.'s activity and mechanism in human colon carcinoma HCT116 and RKO cells. Furthermore, we also used the p53-knockout of HCT116 cells and the p53 loss of RKO cells for elucidating the role of p53. Coscinoderma sp. inhibited cellular viability independently of the p53 status. Therefore, we compared the expression level of cell death-related proteins by Coscinoderma sp. in HCT16 and in HCT116 p53KO cells. Coscinoderma sp. increased p53 level and NOXA levels and induced apoptosis under the condition of p53 existence. On the other hand, Coscinoderma sp. increased p21 and mTOR levels in HCT116 p53KO cells. These results suggest that Coscinoderma sp. induced anti-proliferation effect through different pathway depending on p53 status.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.20 no.4
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• pp.389-398
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• 2002

As the necessity of land information has increased according to development of computer and Information-communication, people have been interested in the satellite measurement system that can update Cadastral and Geographical information rapidly and exactly. Most Cadastral base points which had limitation of measurement technology in the 1910s were less accurate and were destroyed through the Korean War. They also many problems in the process of reinstallation. So, they require the quick and correct method of measurement in re-equipment of a base point and a parcel based survey and so on. This study intends to present the GPS survey direction by understanding and analysing all sorts of problems rising in case of applying the GPS to cadastral area in order to increase the efficiency of the GPS measurement, and also develop the GPS kinematic survey program to apply to the efficiency of a kinematic survey. As a result of research, I could confirm the accuracy of Cadastral base points in Kwangju area by using Korea GPS array and a base point, and could get the result similar to existent cadastral survey result with the coordinate conversion program of Cadastral technology research institute. We however have to pay our attention to the transformation of the plane coordinates because the difference between tens of cm and the existing result can outbreak according to the Gauss conformal double projection method. And, I could figure out the practicality of the developed GPS kinematic survey program, compared with common use program. I expect that it can be applied to the digital cadastral survey and the cadastral map renewal as well.

• Geotechnical Engineering
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• v.10 no.2
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• pp.121-140
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• 1994

This paper presents the probabilistic model to evaluate the three-dimensional stability of layered deposits and c-0 soil slopes. Rotational slides are assumed with a cylindroid control part terminated with plane ends. And the potential failure surfaces in this study are assumed with the logarithmic spiral curve refracted at boundary of layers. This model takes into consideration the spatial variabilities of soil properties and the uncertainties stemming from insufficient number of samples and the discrepancies between laboratory measured and in -situ values of shear strength parameters. From the probabilistic approxi mate method (FOSM and SOSM method), the mean and variance of safety factor are calculated, respectively. And the programs based on above models is developed and a case study is analysed in detail to study the sensitivity of results to variations in different parameters by using the programs developed in this study. On the basis of thin study the following conclusions could be stated : (1) The sensitivity analysis shown that the probability of failure is more sensitive to the uncertainty of the angle of internal friction than that of the cohesion, (2) The total 3-D proability of failure and the critical width of failure are significantly affected by total width of slope. It is found that the total 3-D probability of failure and the critical width of failure increase with increasing the slope width when seismic forces do not exist and the total 3-D probability of failure increases with increasing the slope width and the critical width of failure decreases when seismic intensity is relatively large, (3) A decrease in the safety factor (due to effect such as a rise in the mean ground water level, lower shear strength parameters, lower values for the correction factors, etc.) would result in reduction in the critical width of failure.

• Journal of Digital Convergence
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• v.14 no.3
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• pp.453-464
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• 2016

This study started from the basis of necessity on the researches which asserts that parental rearing behavior in the modern society should change reflecting the social change of sociocultural environment. For this, parental rearing behavior of social constructivism and existing parental rearing behavior were contemplated while construct of parental rearing behavior was explored on the basis of main causes from Vygotsky's theory in order to prepare paradigm of new parental rearing behavior. As far as the method of study goes, various literature from relevant scholars were analyzed, centering various previously conducted studies pertaining to parental rearing behaviors as well as Vygotsky's theory. Also, the validity of the contents was confirmed through consult and revision from three experts. As the result, five factors were extracted. First, factor of cooperative interaction on social interaction. Secondly, emphasis on Internalization factor on social constructive behavior. Thirdly, potential development factor in zone of proximal development. Fourthly, instructional conversation factor as semiotic medium. Lastly, assistance factor as scaffolding. As a result, new paradigm of parental rearing behavior was presented and opened a prospect in developing the touchstone of parental rearing behavior pursuant to social constructivism.

• Journal of Korean Society for Geospatial Information Science
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• v.9 no.2 s.18
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• pp.29-36
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• 2001

The purpose of this paper is to describe the Disaster Management System Development of Enterprise GIS at the Kangwon Province in Korea. This project is included into 'the Kangwon Enterprise GIS 21 plan'. The Division of Disaster Management is in the middle of the 2-year project of the Disaster Management System development, appropriate for business performed at the Departments of Forestry, Culture, Environment, Tourism, etc. At the 1st phase of CIS implementation, for more than half a year we focused on the necessity of management of disasters. In the planning process, we needed long-term information on the whole area of Kangwon. In the assessment and response processes, we needed real-time data from Korean Meteorological Administration and other agencies. All the above information was carefully studied and referred to. ESRI's new GIS technologies solve the natural hazard/disaster problems. For example, hazardous materials routing often needs to be found the least expensive path through a roadway network. In the circumstances given, we can choose the departure point and destination of the vehicle, which carries the materials. It's also possible to minimize overall risk and costs of disaster problems by making a plan of people and possessions evacuation from the disaster area in short time limits. We can meet all the above goals using the latest ESRI's technologies.

• Journal of the Korean Society of Food Science and Nutrition
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• v.43 no.8
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• pp.1148-1157
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• 2014

Rice bran (RB), a by-product obtained during polishing of un-milled rice, contains a large quantity of essential nutrients such as minerals, vitamins, fiber, amino acids, and antioxidants. In this study, the anti-obesity effects of stabilized RB addition as a food material in a diet-induced obese animal model were investigated. For the analysis, a total of 32 mice were randomly divided into four groups: normal diet group (ND, n=8), high-fat diet group (HFD, n=8), 20% RB added high fat diet group (HFRB20, n=8), and 40% RB added high fat diet group (HFRB40, n=8). The animals were sacrificed after 7 weeks. Body weight gain, various adipose tissue weights, blood glucose concentration, and serum leptin level of the HFRB40 group were found to be significantly lower than those of the HFD group. Moreover, antioxidant enzyme activity of the HFRB40 group was significantly higher than that of the HFD group. However, the HFRB20 group did not show significantly different values. The results of this study show that RB (40%) addition reduces body weight gain and improves obesity-related parameters. These results suggest RB could be considered as a functional additive material for the manufacture of anti-obesity products, and 40% RB addition would be the physiologically effective level.

• Korean Journal of Social Welfare
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• v.56 no.4
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• pp.5-34
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• 2004

This study aims to find out the determinants of burnout in order to better understand the burnout process among social workers. For this purpose, a hypothetical model which explains the relationships among 8 job-related stressors (role ambiguity, role overload, difficulties in solving problems of clients, conflict with the clients, lack of support from the supervisor, closed communication pattern, bureaucracy, and lack of accountability), 4 mediators (job-stress, professional role performance, abiding by the agency policy and partiality in service delivery), and 4 dimensions of burnout (physical exhaustion, psychological exhaustion, depersonalization and personal accomplishment) was developed. Using the data collected from 207 social workers, the hypothetical model was tested. For data analysis, a path analysis was used, and the best-fitting model was found(df=66, $x^2$=63.250, GFI=0.962, CFI=1.00). As a result of this study, the following results were found. Burnout among social workers was increased by the 6 job-related stressors(role ambiguity, role overload, difficulties in solving problems of clients, conflict with the clients, lack of support from the supervisor, closed communication pattern). Job-stress, the mediating variable of the emotional path to burnout, increased professional role performance and the abiding by agency policy, and finally increased burnout. On the other hand, professional self-efficacy (which consists of professional role performance, abiding by agency policy and partiality in service delivery), the mediationg variable of the cognitive path to burnout, reduced burnout when the professional role performance was high, and abiding by agency policy and partiality in service delivery were low.

• Journal of the Korean Geographical Society
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• v.36 no.5
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• pp.578-592
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• 2001

Based on a survey sample of farm households in three provinces of Korea, this article reports the perspectives of fuel-time farmers regarding trade liberalization, its effects on their lives, and the future of small-scale farming. While the agricultural sector is being transformed under neoliberal policies, farmers, with life or no preparation for a global market order, are forced to modernize their farming operations. The findings from the survey indicate that farmers accede to terms of global integration in principle while disapproving state rural policies in practice. The survey data also confirm that intra-regional differences in farmers'perceived satisfaction with living conditions, government farm policies, and socio-economic/labor issues. Disparities in the degree of discontent with government policies and socio-economic well-being are explicit between the relatively diversified region of Kyonggi Province and the farming-dependent regions of Chunbuk and Kyongbuk Provinces. The overall findings uphold that most farmers who have not been fully exposed to free market mechanisms are confronted by increased uncertainties and economic hardships. The findings propound that agricultural/rural policies need to reflect long-term, macroeconomic changes, and regionally/locally-based agricultural structure.

• Journal of Korean Tunnelling and Underground Space Association
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• v.20 no.4
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• pp.657-669
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• 2018

In recent years, the development of complex urban areas has become saturated and much attention has been focused on the development of underground space, and deep excavation is frequently performed in order to increase the utilization of underground space due to the enlargement of buildings and the high rise of buildings. Therefore, in this study, we tried to understand the behavior of the braced wall and the behavior of the tunnel adjacent to the wall according to the stiffness of the wall and the distance between the tunnel and wall. As a result of the study, the deformation of the braced wall tended to decrease with increasing the stiffness of the wall, and the axial force acting on the struts was also different according to the stiffness of braced wall. When the stiffness of the braced wall is small (2 mm), the point at which the axial force of the braces maximizes is near 0.3H of the wall. When the stiffness of the braced wall is large (5 mm), the axial force is maximum at around 0.7H of the wall. Also, the tunnel convergence occurred more clearly when the separation distance from the braced wall was closer, the stiffness of the wall was smaller, and the tunnel convergence was concentrated to the lower right part. The ground settlement due to the excavation of the ground tended to decrease as the distance between tunnel and braced wall was closer to that of the tunnel, which is considered to be influenced by the stiffness of the tunnel.

• Korean journal of communication and information
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• v.36
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• pp.7-41
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• 2006

This study criticizes the wave of liberalization, privatization, thoughtless and uncontrolled over-competition in the electronic communication networks area. This criticism is based on the 'transport economics' on one side, the 'network neutrality debate' on the other side. Through these standpoints, this study insists that it needs to deal with a social agenda related to the problems such as unplanned and unbalanced development of electronic communication networks, double/tripple-investment in the communication industry, conflicts among network companies and the decline of public values. Also does this study stress on the new ideas in the electronic communication network policy and planning to manage these problems. Electronic communication networks are converging and their borders are blurred. As a result of these flows, the field of information technology, media and contents is faced with radical changes. These changes could be so critical and complicated that nobody can diagnose their multi-level implications. However, the one thing sure is that we should start from the communication networks to think and control a communication system. Therefore, we should discuss and plan the now-and-future of communication infrastructure and its management. we need not only a market mentality but also a socio-cultural mentality. In this respect, this study does insist that it requires the vision of digital democracy and democratic communication ecology to put the steps toward social communication system.