• Radiation Oncology Journal
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• v.27 no.2
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• pp.84-90
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• 2009

Purpose: The effect of concurrent chemoradiotherapy was analyzed in elderly patients when used in the treatment of locally advanced esophageal cancer. Materials and Methods: The retrospective analysis included 28 elderly patients aged 65 or older, with histopathologically confirmed squamous cell carcinoma of the esophagus, underwent concurrent chemoradiotherapy from January 2001 to July 2007. The squamous cell carcinoma disease stages included 8 patients (28.8%) in stage IIa, 10 patients (35.7%) in stage IIb, and 10 patients (35.7%) in stage III. Fractionated radiotherapy was performed with a 6 MV or 10 MV X-ray for 45~63 Gy (median: 59.4 Gy). Chemotherapy was applied concurrently with the initiation of radiotherapy. A 75 mg/$m^2$ dose of Cisplatin was intravenously administered on day 1. Further, 5-FU 1,000 mg/$m^2$ was continuously administered intravenously from days 1 to 4. This regimen was performed twice at 3-week intervals during radiotherapy. Two cycles of consolidation chemotherapy was performed after radiotherapy. Results: The follow-up period was 3~72 months (median: 19 months). The treatment responses after concurrent chemoradiotherapy included a complete response in 11 patients (39.3%), a partial response in 14 patients (50.0%), and no response in 3 patients (10.7%). The overall response rate was 89.3% (25 patients). The overall 1-, 2- and 3-year survival rates were 55.9%, 34.6% and 24.2%, respectively. The median survival time was 15 months. Two-year survival rates of patients with a complete response, partial response, and no response were 46.2%, 33.0%, and 0%, respectively. The stage and tumor response after concurrent chemoradiotherapy were statistically significant prognostic factors related with survival. No treatment-related deaths occurred in this study. Conclusion: Concurrent chemoradiotherapy is a relatively effective treatment without serious complications in elderly patients with locally-advanced esophageal cancer.

• Journal of Chest Surgery
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• v.29 no.9
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• pp.1010-1016
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• 1996

Thymectomy is an accepted therapeutic modality for patients with myasthenia gravis. The selection of patients for operation, the timing of operation and the surgical approach are still controversial. We reviewed 82 patientsraged 13 to 66 years; mean age, 37.7 years treated with transsternal thymectomy between January 1983 and December 1994. Patients were symptomatically staged according to the modified Osserman's classification. There was one hospital death and postoperative follow-up was obtained on 75 patients. During a mean follow up of 56.9 months, 64 patients (85.3%) benefited from the operation with complete remis ion achieved in 28(37.3%). The thyroid disease was present in 8 patients, of whom 7(87. 5%) achieved complete remission in contrast to 21 (31.3%) of the 67 patients without thyroid disease. The disease duration less than 2 years in 32 patients was associated with complete remission in 16 (50%) in contrast to remission in 12(27.4%) of the 43 patients whose disease duration was more than 2 years. In conclusion, the complete remission rate after transsternal thymectomy was affected by the presence of thyroid disease and disease duration. Myasthenia gravis with late onset(>40 years), thymoma pathology, old age and male gender appear to decrease the complete remission rate after transsternal thymectomy, although it was not statistically significant. There was no difference of complete'remission rate between normal and hyperplasia of thymus. Transsternal thymectomy was found to be beneficial in most patients with myasthenia gravis, but the majority of patients with ocular disease did not b nefit from the operation.

• Korean Journal of Environment and Ecology
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• v.36 no.2
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• pp.150-164
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• 2022

The objective of this study is to analyze the biodiversity changes and characteristics of the benthic macroinvertebrate community in the Nakdong River with eight weirs, which was constructed as one of the Four Major River Restoration Projects from May to October 2020. The study also includes the analysis of changes in the major groups of benthic macroinvertebrates for about ten years, from 2010 to 2020. The surveys collected 97 species of benthic macroinvertebrates belonging to 83 genera, 52 families, 18 orders, five classes, three phyla, and 128.1 individuals/m². Chironomidae sp. and Tubificidae spp., which are pollutant indicators, dominated throughout the sections. The community analysis result shows the average dominant index and the diversity index of 0.62±0.20 and 1.87±0.63, respectively, and indicated the most stability of the freshwater ecosystem in the upper stream of the Nakdong River. The survey showed dominance by Chironomidae sp. at the center of the Nakdong River weir and the most unstable community in Chilgok and Gangjeong Goryeong weirs. The results of the community stability analysis showed a high distribution of the characteristic group I with high resilience and resistance and small distribution of characteristic group III with low resistance and resilience, indicating a very unstable condition of communities in the Nakdong River weir section. Predators were relatively abundant among the functional feeding groups (FFGs), whereas shredders, gathering-collectors, and filtering-collectors were relatively lower. Among the habitat orientation groups (HOGs), burrowers and climbers were dominant, indicating a wide distribution of groups in ecosystems with low dissolved oxygen. An endangered species level II of Macromia daimoji was found in Sangju and Nakdan weirs. The analysis results for 10 years from 2010 showed that the number of species and populations increased immediately after the dam construction but plummeted in 2016 and are now stabilizing. Chironomidae spp. has been dominant in all sections over the past 10 years, and they are currently maintained at a rate of about 50%. The EPT groups have decreased significantly since 2011, and the Plecoptera and Trichoptera of the group have not yet been restored. The population of Tubificidae spp. showed an increase after construction was completed in 2012 and drastically increased in 2015 and 2020. The species of Cristaria plicata, designated as endangered species level I, has not been observed since 2011 in Hapcheon Changnyeong weir. Moreover, Macromia daimoji was rarely observed in seven weirs until 2015, and it has been confirmed that the current distribution habitat has decreased rapidly.

• Journal of the Korean Association of Geographic Information Studies
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• v.17 no.2
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• pp.44-58
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• 2014

In this study, a standard vector data model was developed for interoperability of river-geospatial information and for verification purpose the applicability of the standard vector model was evaluated using a model to RIMGIS vector data at Changnyeong-Hapcheon & Gangjung-Goryeong irrigation watershed. The standards from ISO and OGC were analyzed and the river geospatial data model standard was established by applying the standards. The ERD was designed based on the analysis information on data characteristics and relationship. The verification of RIMGIS vector data included points, lines and polygon to develope GDM was carried out by comparing with the data by layer. This conducting comparison of basic spatial data and attribute data to each record and spatial information vertex. The error in the process of conversion was 0 %, indicating no problem with model. Our Geospatial Data Model presented in this study provides a new and consistent format for the storage and retrieval of river geospatial data from connected database. It is designed to facilitators integrated analysis of large data sets collected by multiple institutes.

• Korean Journal of Ecology and Environment
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• v.52 no.4
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• pp.316-323
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• 2019

This study was carried out to investigate sedimentary environment changes in Nakdong River sediments. For this purpose, sediments at six sites upstream of Gangjeong-Goryung Weir in the middle of the Nakdong River were collected before and after the rainy season. Particles size, IL, TOC, TN, TP, and SRP were analyzed for the sediment environment. The changes in the watershed environment before and after the rainy season (precipitation, discharge, and SS concentration) were investigated. After the rainy season, the amount of precipitation and discharge increased more than three times, and the average concentration of SS in the stream increased more than two times. Fine grained sediment and the concentrations of IL, TOC, TN, TP, SRP were increased after the rainy season. As a result of sediment contamination assessment, IL was 19~68% of the reference value, TN and TP were 21~76% and 21~58% of the reference value. The result showed strong correlation between particle size (Silt+Clay) and organic contents of sediment (IL, TOC, TN, TP and SRP). It is considered that the change of the river watershed environment (precipitation, discharge) is an important factor of the change of sedimentation environment.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.33 no.3
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• pp.997-1005
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• 2013

Since the cross-sectional shape of the Nakdong river is compound type, the water stage rises up to the top of the flood plane, as the flow discharge increases during the extreme rain storm in summer. The recent increase of rainfall intensity and flood frequency results in the immersions of parks and hydrophilic facilities located in the flood plain. Therefore it is necessary to analyze the hydraulic characteristics evolved by the extreme rain storm in the flood plain. The study reach ranging from the Gangjeong Goryeong Weir and the Dalseong Weir, where several hydraulic facilities are located along the channel, was selected and numerical simulations were conducted for 42 hours including the peak flood of the typhoon Sanba. The 2-D transient model, FaSTMECH was employed and the accuracy of the model was assessed by comparing the water level between the simulation results and the measured ones at a gauging station. It showed a high correlation with $R^2$ of 0.990, AME of 0.195, and RMSE of 0.252. In addition, the inundation time, the inundation depth, the inundation velocity, and the shear stress variation in the flood plain facilities were analyzed.

• Proceedings of the Korea Water Resources Association Conference
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• 2015.05a
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• pp.103-103
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• 2015

유류유출사고와 같이 하천 수표면의 흐름에 따라 이동 확산하는 부유성 오염물질의 혼합해석을 위해 많은 연구자들은 입자추적모형을 사용한 혼합모의를 수행해왔다. 입자추적모형에서 오염물질의 혼합은 평균 유속 분포에 의한 결정론적인 이동과 난류유동에 의한 무작위적인 혼합으로 나타내며, 난류혼합에 의한 수평확산은 난류확산계수로 조절한다. 따라서 표면흐름에 의한 난류확산계수의 산정을 위해 많은 연구자들은 부유성 입자를 이용한 실내실험을 수행하여 수평확산계수를 산정했고(Engelund, 1969; Cederwall, 1971), 최근에는 GPS의 발전으로 인해 해양영역에서 GPS를 장착한 표면부자를 활용한 확산실험을 통해 수평확산계수를 산정한 바 있다(Kjellson and $D{\ddot{o}}{\ddot{o}}s$, 2012; Alpers 등, 2013). 하천수질오염사고의 약 43.5%가 유류유출에 의한 것이며(환경부, 2013), 이에 따라 표면흐름에 의한 오염물질 혼합해석이 필요하나, 하천에서 수평확산계수 산정을 위한 현장실험연구는 부족한 상황이다. 따라서 본 연구에서는 낙동강 본류에서 GPS부자를 이용한 입자추적실험을 수행하여 표면흐름에 의한 확산계수를 산정했다. GPS부자를 이용한 입자추적실험은 낙동강의 강정고령보 하류와 구미보 하류의 각각 세 지점에서 수행되었다. GPS부자는 바람에 의한 교란을 최소화하기 위해 지름 10 cm의 구형으로 제작하였으며 시범테스트를 통해 입자의 주 궤적 변화가 크지 않은 지점에 GPS부자를 투입했다. GPS부자는 오염물질의 사고유출을 가정하여 한 지점에 투입했고 GPS부자 사이의 간섭을 최소화하기 위해 25 ~ 35개의 GPS부자를 이용했다. 표면흐름에 의해 이동하는 부자의 위치는 GPS에 시계열로 저장됐고 ADCP를 이용하여 실험당시의 수리량을 측정했다. 입자위치의 시계열자료로부터 GPS부자의 확산범위의 시간변화를 계산했고 단순 모멘트법을 이용하여 종, 횡 방향 확산계수를 계산했다. 그 결과, 종 방향 확산계수는 $0.003{\sim}0.041m^2/s$로 계산되었고 횡 방향 확산 계수는 $0.001{\sim}0.012m^2/s$로 계산되어, 흐름방향의 유속성분에 의한 확산이 지배적인 것으로 나타났다. 지류 합류부에서는 이송이 지배적인 혼합이 발생되었고(Pe>1) Pe의 증가에 따라 수평확산계수가 감소되었다. 25~35개 GPS부자 궤적의 앙상블 평균으로부터 계산한 Integral time scale은 모멘트법으로부터 계산한 종, 횡 방향 확산계수와 비례하는 것으로 나타나, Taylor(1921)의 이론과 일치했다. 또한 실험수로에서 수행된 기존연구결과와 비교한 결과, 하폭 대 수심비, 마찰항의 증가에 따라 수평확산계수가 증가하는 경향을 나타내었다.

• Journal of Korea Water Resources Association
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• v.52 no.2
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• pp.163-172
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• 2019

The linear and cross-sectional shapes of the natural river channel are subjected to continuous changes in time and space due to the interaction with the flow of water and sediment transport. This study aims to investigate the morphological characteristics and change patterns of river channel quantitatively for the middle reach of Nakdong River, which has undergone large scale riverbed dredging and construction work, as Four Major River Restoration Project. A series of bathymetry and near-river survey has been conducted to obtain the detailed terrain information for the study area. The properties related to the linear and cross-sectional characteristics of river channel have been calculated based on the filed survey data and analyzed with comparing the survey data obtained in 2012 for the project completion. Since there has not been enough time for meaningful terrain change to take place, it was not possible to extract special tendency in the degree and aspect of terrain change. However, it is necessary to make regular examinations to the patterns and degree of river channel change using the proposed methodology.

• Korean Journal of Ecology and Environment
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• v.52 no.1
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• pp.50-64
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• 2019

Recently, quantitative analyses of food web structure based on carbon and nitrogen stable isotopes are widely applied to environmental assessments as well as ecological researches of various ecosystems, particularly rivers and streams. In the present study, we analyzed carbon and nitrogen stable isotope ratios of POM (both planktonic and attached forms), zooplankton, benthic macroinvertebrates and fish collected from 6 sites located at Nakdong River. Samples were collected from upstream areas of 5 weirs (Sangju, Gangjeong-Goryeong, Dalseong, Hapcheon-Changnyeong, and Changnyeong-Haman Weirs) and one downstream area of Hapcheon-Changnyeong Weir in dry season (June) and after rainy season (September). We suggested ranges of their carbon and nitrogen stable isotope ratios and calculated their trophic levels in the food web to compare their temporal and spatial variations. Trophic levels of organisms were relatively higher in Sangju Weir located at upper part of Nakdong River, and decreased thereafter. However, the trophic levels were recovered at the Changnyeong-Haman Weir, the lowest weir in the river. The trophic level calculated by nitrogen stable isotope ratios showed more reliable ranges when they were calculated based on zooplankton than POM used as baseline. The suggested quantitative ecological information of the majority of biological communities in Nakdong River would be helpful to understand the response of river food web to environmental disturbances and can be applied to various further researches regarding the quantitative approaches for the understanding food web structure and function of river ecosystems as well as restoration.