• Title/Summary/Keyword: 간 조직 검사

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무항생제 돈육 생산을 위한 생균제 급여 효과

  • Ha, Ji-Hui;Park, Gi-Hun;Gang, Seok-Mo;Ha, Gyeong-Hui;Lee, Chang-U;Kim, Il-Seok;Song, Yeong-Min;Jin, Sang-Geun
    • Proceedings of the Korean Society for Food Science of Animal Resources Conference
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    • 2005.05a
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    • pp.164-168
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    • 2005
  • 복합생균제를 급여하지 않은 대조구, 복합생균제 KBC1144 0.1% 급여구(T1), YC2000 0.1% + KBC1144 0.1% 급여구(T2)로 실험한 결과 일반성분에서 수분과 조회분은 유의적인 차이가 없었고, 조단백질은 T2 처리구가 가장 높았고, 조지방은 T2 처리구가 가장 낮게 나타났으며, pH는 대조구가 처리구들에 비하여 낮게 나타났다. 보수력은 대조구가 가장 높고, T1 처리구가 가장 낮게 나타났다. 콜레스테롤 함량은 처리 간에 유의적인 차이는 보이지 않았으나 두 가지 미생물제재를 활용한 T2 처리구가 가장 낮은 경향이었다. T2 처리구가 육색의 적색도는 높고, 지방색의 명도는 높고 황색도는 낮았다. 조직감은 T1 처리구가 높고, T2 처리구가 낮았으며 가열육의 관능검사에서 다즙성은 처리구들이 대조구보다 높았다. 필수지방산인 리놀산과 아라키돈산은 T1 처리구가 다른 두 구에 비하여 높게 나타났고, 불포화지방산, 필수지방산 및 필수지방산/불포화지방산 비율은 T1 처리구가 가장 높고 T2 처리구가 가장 낮게 나타났으며 아미노산 함량은 T2 처리구가 다른 두 구에 비하여 높았다. 종합적으로 두 복합미생물제재를 혼합 사용한 T2 처리구가 무항생제 돈육 생산을 가능하게 하였으며, 육질 특성면에서도 가장 좋은 결과였다.

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New Measurement of Whitening Effects by Using Confocal Scanning Laser Microscope (CSLM) (Confocal Scanning Laser Microscope (CSLM)을 이용한 신규 미백 효과 측정 연구)

  • Kim, Myong Ki;Cho, Seok-Cheol;Nam, Gaewon
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.41 no.3
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    • pp.279-285
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    • 2015
  • Hyperpigmentation on face is a highly anxiety-producing symptom, especially for women from the aspect of beauty. Pigmentation of the skin is related to the amount of melanin that provides protection against UV radiation. In vivo reflectance confocal microscopy is a non-invasive imaging tool allowing visualization of the skin without tissue alteration, by placing a microscopy directly on the living skin. The aim of this study was to develop the new evaluation method of whitening effects using in vivo reflectance confocal microscopy and to validate other instruments for measuring skin colors, and UV-induced hyperpigmentation was elicited on the inside skin of the forearm. It suggested that the new method for whitening effects using the confocal microscopy was useful to evaluate the de-pigmentation products and to easy for understanding to customers.

Patent Ductus Arteriosus in the Dog (견(犬)에서의 개방성(開放性) 동맥관(動脈管) 증례(症例))

  • Kim, Myung Cheol;Kim, Kyo Joon;Lee, Young
    • Korean Journal of Agricultural Science
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    • v.14 no.1
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    • pp.191-195
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    • 1987
  • The ductus arteriosus (Botallo's duct) is a vascular communication between the pulmonary artery near its bifurcation and the aorta distal to the origin of the left subclavian artery. A surgical operation was tried in the shepherd dog which was affected by patent ductus arteriosus. The patient was six months old and weighed about 11kg. Pentobarbital sodium, 26 mg/kg was used intravascularly for the anesthesia. And then a respirator was used for the patient. The thoracotomy incision was made over the fourth intercostal space on the left and the ductus arteriosus was ligated twice. But the patient revealed ventricular fibrillation at three minutes after ligations of ductus arteriosus. So the cardiac massage was done after incision of pericardium and then the defibrillator was used for the defibrillation. But the patient was not recovered without effect. It was considered that if there is complication or cyanosis, the adaptability of surgical operation should be specially considered. Histologically, chronic passive congestion of liver was observed.

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Effects of Alcohol Administration and Dietary Folate on Plasma Homocysteine and Liver Histopathology (알코올과 식이엽산수준이 혈장 Homocysteine, 간기능, 간 조직검사에 미치는 영향)

  • 장남수;김기남;김연수;서종복;권오옥
    • Journal of Nutrition and Health
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    • v.31 no.7
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    • pp.1121-1129
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    • 1998
  • The critical role of folate vitamin in the remethylation pathway for methionine synthesis from homocysteine has been well documented. Hyperhomocysteinemia resulting from inadequate folate nutrition has been implicated in increased incidence of macrovascular diseases, colorectal cancer, neural tube defects, etc. Chronic exposure to ethanol impairs folate nutrition and one-carbon metabolism in the liver, which often results in fatty liver due to a defective remethylation process. This study was carried out to investigate the chronic effects of moderate levels of alcohol and dietary 131ate on plasma homocysteine levels, and on histopathology and biochemical functions of the liver Rats were raised on experimental diets with three levels of folate(0, 2, 8mg/kg diet), and 50% ethanol(1.8m1/kg body weight) was administered intragastrically by intubation tubes three times a week for 10 weeks. Plasma homocysteine concentrations were found to be significantly influenced by dietary folate intake and alcohol administration. Among all treatment groups, Plasma homocysteine levels were highest in the animals receiving a combined treatment of folate deficient diet and alcohol administration. Plasma homocysteine concentration was negatively correlated with folate concentration in the plasma(p<0.01) and liver(p<0.05). Among alcohol treated rats, increase in plasma homocysteine values due to ethanol was prevented by 131ate supplementation. When liver histological tests were performed, macrovascular and microvascular fatty changes and spotted necrosis were observed more frequently in folate-deficient animals diet than those on folate-adequate and folate-supplemented diets in alcohol-treated rats. These results indicate that folate supplementation above the recommended level might be beneficial in the prevention of alcohol-related hyperhomocystei-nemia and abnormal histologic changes in the liver due. (Korean J Nutrition 31(7) : l121-l129, 1998)

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Effect of dietary quality on periodontal diseases in Korean adults: the Korea National Health and Nutrition Examination Survey (2016-2018) (한국 성인의 식생활의 질이 치주질환에 미치는 영향: 국민건강영양조사 제7기(2016-2018) 자료 활용)

  • Park, Jung-Eun
    • Journal of Korean society of Dental Hygiene
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    • v.21 no.5
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    • pp.535-543
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    • 2021
  • Objectives: This study investigated the relationship between the Korean healthy eating index (KHEI) and periodontal disease in the Korean adult population. Methods: The data used in the analyses were obtained from the seventh Korean National Health and Nutrition Examination Survey (2016-2018). Data were analyzed by chi-square tests and t-test. Multiple regression analysis was also performed to assess the association between KHEI and periodontal disease. Statistical significance was set at p<0.05. Results: Multiple logistic regression analysis adjusted for socioeconomic variables showed that medical and health behavior variables were significantly related to the KHEI 1 (<63.7, odds ratio [OR]: 1.23, 95% confidence interval [CI]: 1.03-1.46), KHEI 2 (63.7-79.9, OR: 1.14, 95% CI: 0.97-1.34), and risk for periodontal disease. Conclusions: The results showed a significant association between the KHEI and periodontal disease in the Korean adult population.

EMG effects of abdominal muscle on multiple forms of exercise (여러 형태의 복부 운동에 대한 복근의 EMG 효과)

  • Yoon, Wan-Young;Cho, Seok-Cheol
    • Journal of the Korea Convergence Society
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    • v.10 no.2
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    • pp.309-313
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    • 2019
  • This study examined the response of the EMG of URA, LRA, IO, EO and RFM of various types of abdominal motion (crunch, spine V-up on ball, prone V-up on slide board, prone V-up on TRX, and prone V-up power wheel). The subjects performed anisometric contact of abs during these exercises. Tests have shown that there were no statistically significant differences between EO, URA and LRA between any movements. However, during the inspection of IO, the positive-wawed V-up motion showed significantly greater muscle activity than during the slide movement. Also, EMG activity during crunch was significantly lower than any other five exercises. These results indicate that in the implementation of equilateral absolutism, the equipment-free based exercise gives an impetus similar to equipment-based exercise. Abdominal muscle tissue is considered one of the five components that make up an individual's core. The abdominal muscles also ensure proper functioning of the lumbar spine. Although all abdominal muscles contribute to lumbar stabilization, TA & IO has been shown to perform major stabilizers.

Clinical Practice Guidelines for Hepatocellular Carcinoma: Current and Future Perspectives (간암 진료가이드라인의 현재와 전망)

  • Bo Hyun Kim;Joong-Won Park
    • Journal of Digestive Cancer Research
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    • v.4 no.1
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    • pp.21-28
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    • 2016
  • Hepatocellular carcinoma (HCC) is rather unique. Most of HCC patients have underlying chronic liver diseases with or without cirrhosis and the prognosis of HCC depends on the liver function, as well as the tumor extent. Non-invasive diagnosis of HCC can be made with certain risk factors and specific imaging findings (e.g. hypervascularity). Patients with HCC can receive surgical resection, radiotherapy, and systemic chemotherapy as other solid malignancies. HCC has more treatment options such as liver transplantation, transarterial chemoembolization (TACE) and radiofrequency ablation (RFA). A variety of practice guidelines for HCC has been published by many academic societies. Different healthcare systems and availability of resources also affect the practice guidelines; therefore, practice guidelines have similarities and dissimilarities. Herein, we review the current status of practice guidelines for HCC and future perspectives for the improvement of guidelines are also discussed.

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Upregulation of Connexin43 Expression in Mitral Valves in a Rabbit Model of Hypercholesterolemia (고콜레스테롤혈증을 유발한 토끼의 승모판막에서 Connexin43 발현의 증가)

  • Kwon, Jong-Bum;Park, Chan-Beom;Sa, Young-Jo;Kim, Young-Du;Moon, Seok-Whan;Kim, Chi-Kyung
    • Journal of Chest Surgery
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    • v.43 no.4
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    • pp.356-363
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    • 2010
  • Background: Connexin 43-mediated gap junctional communication plays an important role in atherosclerosis. Numerous studies have demonstrated a correlation between mitral valve annular calcification and atherosclerotic disease. However, the relevance of connexin 43 to mitral valve disease remains unclear. We hypothesized that the mechanism contributing to mitral valve disease is associated with alterations in cell-to-cell communication mediated by changes in Connexin 43 expression. Material and Method: Twenty male New Zealand rabbits were divided into two groups: animals in group 1 (n=10) were fed a normal chow diet, whilst those in group 2 (n=10) received a diet containing 1% cholesterol for 12 weeks. After sacrificing the animals, the mitral valves were excised and analyzed with immunohistochemical staining and Real-time Reverse Transcriptase polymerase chain reaction (real time RT-PCR). Result: Myofibroblasts and macrophages were found concentrated within the endothelial layer on the ventricular side of the leaflet in the cholesterol diet group. Immunohistochemial staining showed elevated expression of connexin43 in the cholesterol diet group. Real-time RT-PCR revealed increased connexin43 mRNA levels in mitral valves from hypercholesterolemic animals. Conclusion: Our finding that connexin43 expression is increased in mitral valves of hypercholesterolemic rabbits suggests that alterations in cell-to-cell communication via connexin43 containing gap junctions play a role in the development of mitral valve disease in hypercholesterolemia.

The Toxicological Pathologic Study of Amanita muscaria in Sprague-Dawley Rat (Amanita muscaria 경구투여 시 Sprague-Dawley Rat에서의 독성병리 연구)

  • Kim, Jin;Kim, Hyeong-Jin;Kim, So-Jung;Kim, Byeong-Soo;Kim, Sang-Ki;Park, Byung-Kwon;Park, Young-Seok;Cho, Sung-Dae;Jung, Ji-Won;Nam, Jeong-Seok;Choi, Chang-Sun;Lee, Seung-Ho;Jung, Ji-Youn
    • Journal of Life Science
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    • v.19 no.8
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    • pp.1152-1158
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    • 2009
  • For the toxicological pathologic study of amanita muscaria, we have investigated single and repeated dose toxicity in Sprague-Dawley (SD) rats. Single dose toxicity study was identified as catalepsy, incline and tail pinch methods (control 0 mg/kg, low 3.3 mg/kg, middle 16.5 mg/kg, high 33.0 mg/kg). Repeated dose toxicity study was carried out in blood tests, serum tests and histopathological methods. Neurotoxicity - muscle paralysis, and convulsion and loss of movement - was observed at 33.0 mg/kg group in the single dose toxicity study. Dysfunction of liver and kidney were shown in the repeated oral administration of the amanita muscaria at 3${\sim}$4 weeks. Serum chemistry results revealed a marked increase of LDH [Lactate Dehydrogenase (3181.5 IU/L; normal 230-460 IU/l)], ALT [Alanine transaminase (124.0 IU/l; normal <40 IU/l)] but the kidney was normal. Histopathological results show interstitial edema and tubular epithelial necrosis in the kidney. These results suggest that amanita muscaria has a neurotoxic effect and causes dysfunction of liver and kidney in the SD rat.

Properties of Dietary Fiber Extract from Rice Bran and Application in Bread-making (미강에서 추출한 식이섬유추출물의 특성 및 제빵에의 응용)

  • Kim, Young-Soo;Ha, Tae-Youl;Lee, Sang-Hyo;Lee, Hyun-Yu
    • Korean Journal of Food Science and Technology
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    • v.29 no.3
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    • pp.502-508
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    • 1997
  • Rice bran dietary fiber extract, which was obtained after termamyl treatment of defatted rice bran contained $27.3{\sim}30.5%$ protein, $49.7{\sim}54.1%$ insoluble dietary fiber, and $1.9{\sim}2.7%$ soluble dietary fiber. Extrusion decreased the insoluble dietary fiber content but increased the soluble dietary fiber content, while roasting did not. Influence those content. Each mineral element content was depended upon heat processing method. Extrusion increased the water binding capacity and L value, while roasting reduced the water binding capacity and L value. Scanning electron microscopy showed damaged cell walls for extruded sample compared to roasted one which had fully collapsed cell walls. The increase of water absorption, developing time, and stability and the of MTI of wheat flour-dietary fiber extract composites with addition of dietary fiber extract were observed by Farinograph. Rice bran dietary fiber extract had an effect on the bread making resulting in increase of bread weight and color of crumb and crust, and decrease of bread volume and texture. As a result of sensory evaluation, appearance, texture, overall acceptability were significantly different from control but flavor and taste were not different significantly up to 6% level. Heat treated samples had differences in mean values, but not significant differences statistically.

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