• Title/Summary/Keyword: 간접노출

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Use of Nitrogen Dioxide as Exposure Marker of Passive Smiking for Non-smoking Service-workers at Restaurants (음식점 비흡연 종업원의 간접흡연 노출량 지표로써 이산화질소 이용)

  • Won-Ho Yang;Young-Lim Kho;In-Kyu(Paul) Han;Chong-Min Lee;Moon-Shik Zong;Moon-Ho Chung
    • Journal of environmental and Sanitary engineering
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    • v.15 no.3
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    • pp.1-7
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    • 2000
  • There is increasing evidence suggestion that passive smoking increases the risk of lung cancer and other disease, though the potential health effects of exposure to environmental tobacco smoke (ETS) is a controversial subject. Since smoking in restaurant is prevalent in Korea, the concern on passive smoking exposure of non-smoking service-workers has been requested. ETS exposure of non-smoking service-workers at restaurant was assessed because they hare spent their times in restaurant indoors. The purpose of this study was feasibility of nitrogen dioxide($NO_2$) as exposure marker of ETS. The results of the study were as follows; 1. Average $NO_2$ concentrations in indoor and outdoor t restaurants were 57.1ppb(${\pm}12.4$) and 54.29ppb(${\pm}9.54$), respectively. Comparing office-workers, service-workers at restaurants were exposured highly. 2. The personal $NO_2$ measurement as exposure marker of ETS could cause the exposure error because $NO_2$ can be generated by combustion appliances in indoor. 3. Service-workers spent their most time(86.6%) in indoor. Mean time spent at restaurant indoors and at home was 9.4 hours and 10.9 hours, respectively. 4. Personal $NO_2$ levels correlated with indoor $NO_2$ concentrations of restaurant (r=0.70) and of their home (r=0.52) rather than of outdoor $NO_2$ concentration of restaurant (r=0.35). The cause of personal $NO_2$ exposure of non-smoking service-workers were considered as smoking of guests and combustion appliance indoors. 5. personal $NO_2$ exposures were estimated using Monte-Carlo simulation and time-weighted model. Estimated personal $NO_2$ level was 47.25ppb(${\pm}8.3$).

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A prediction of the rock mass rating of tunnelling area using artificial neural networks (인공신경망을 이용한 터널구간의 암반분류 예측)

  • Han, Myung-Sik;Yang, In-Jae;Kim, Kwang-Myung
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.4 no.4
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    • pp.277-286
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    • 2002
  • Most of the problems in dealing with the tunnel construction are the uncertainties and complexities of the stress conditions and rock strengths in ahead of the tunnel excavation. The limitations on the investigation technology, inaccessibility of borehole test in mountain area and public hatred also restrict our knowledge on the geologic conditions on the mountainous tunneling area. Nevertheless an extensive and superior geophysical exploration data is possibly acquired deep within the mountain area, with up to the tunnel locations in the case of alternative design or turn-key base projects. An appealing claim in the use of artificial neural networks (ANN) is that they give a more trustworthy results on our data based on identifying relevant input variables such as a little geotechnical information and biological learning principles. In this study, error back-propagation algorithm that is one of the teaching techniques of ANN is applied to presupposition on Rock Mass Ratings (RMR) for unknown tunnel area. In order to verify the applicability of this model, a 4km railway tunnel's field data are verified and used as input parameters for the prediction of RMR, with the learned pattern by error back propagation logics. ANN is one of basic methods in solving the geotechnical uncertainties and helpful in solving the problems with data consistency, but needs some modification on the technical problems and we hope our study to be developed in the future design work.

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Analysis of Condition Changing on Dose Variation using Intraoral Radiation Devices (구내 촬영용 방사선 장치의 촬영조건에 따른 선량변화 분석)

  • Kim, Young-Jae;Lee, Yong-Tak;Song, Hyeon-Cheol
    • Journal of the Korean Society of Radiology
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    • v.6 no.2
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    • pp.137-142
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    • 2012
  • This study is investigated dose change on intra-oral radiography when same conditions under the others unit and same unit under the different exposed conditions. Three different radiation devices were studied. Exposure to the upper anterior, premolar and molar on the variant time and dose measure was using semiconductor radiation dose meter. Obtained film density value was analyzed to the belong in the range of diagnosis. Results for dose of each region were less dissimilar between the maximum and minimum. Its value was different 10 times as many as 3 times. In addition, the range of film density was 2.10 ~ 2.95. These values were exceeded on the allow density of diagnostic value '0.25 ~ 2.0'. Even if the same device and the same condition, measured dose was considerable differance and film density was showed show the inappropriate density range. Those can be caused the patient's re-take and patient's diagnostic errors so patients has affected direct and indirect radiological harm. Therefore, dental radiography devices will be required periodical maintenance and also provided standard on the exposure and processing conditions.

A Study on the Research Trend of Counter-Terrorism: Focusing on Counter-Terrorism studies of the National Police Headquarters (대(對)테러리즘 분야 연구경향분석:치안본부 대테러연구를 중심으로)

  • Lee, Dae sung;Ryu, Sang Il
    • Convergence Security Journal
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    • v.14 no.3_2
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    • pp.83-91
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    • 2014
  • International society got a severe shock from terrorism of hostage, abduction and murder that was committed on a target of Israel athlete delegation in Munich Olympics, West Germany by Black September, a Palestine terrorism organization. Korea with 1986 Asian Games and 1988 Olympics ahead was directly and indirectly exposed to threats of North Korea's nation-support terrorism, a military provocation and a local war limited warfare. This study explores the roles of the police at the time of the National Police Headquarters with regard to counter-terrorism, and analyzed academic research trends of Studies of Counter-terrorism published by the same office between 1983 and 1990. Looking into them shows a fact firstly, that the most frequently appearing key words in common were "terrorism," "hostages," "measures," and "international," etc. Secondly, before and after 1988 Olympics, the key word "Olympics" was frequently addressed. Thirdly, looking at the difference by the year, the key word, "policies of defense and borderlands" was frequently addressed between 1983 and 1984, "terrorism against South Korea," and "civil aircraft" frequently addressed in 1985, and "corporate" in 1986. In 1987, the key word "terrorism trends" was addressed, and in 1990, "international terrorism," and "separatism" were used.

Cytoprotective Effect of Zinc-Mediated Antioxidant Gene Expression on Cortisol-Induced Cytotoxicity (Cortisol 유발 세포독성에 대한 아연 관련 항산화 유전자 발현 증가에 의한 세포보호 효과)

  • Chung, Mi Ja;Kim, Sung Hyun;Hwang, In Min
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.44 no.5
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    • pp.649-656
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    • 2015
  • The protective effect of zinc against cortisol-induced cell injury was examined in rainbow trout gill epithelial cells. Cells exposed to cortisol for 24 h showed increased leakage of lactate dehydrogenase (LDH) as well as decreased cell viability in a dose-dependent manner. Treatment with zinc ($100{\mu}M$ $ZnSO_4$) reduced the severity of both LDH release and cell death as well as protected cells against cortisol-induced caspase-3 activation, indicating reduction of apoptosis. Cortisol-induced cell death, leakage of LDH, and caspase-3 activation were blocked by the glucocorticoid receptor antagonist Mifepristone (RU-486), suggesting that cell injury was cortisol-dependent. In addition, we studied the effect of zinc on the expression of antioxidant genes such as metallothionein A (MTA), metallothionein B (MTB), glutathione-S-transferase (GST), and glucose-6-phosphate dehydrogenase (G6PD) during cortisol-induced cell injury. MTA, MTB, GST, and G6PD mRNA levels increased after treatment with zinc or cortisol, separately or in combination. Higher mRNA levels of MTA, MTB, GST, and G6PD were detected when cells were treated with $100{\mu}M$ $ZnSO_4$ and $1{\mu}M$ cortisol in combination at the same time compared to treatment with zinc or cortisol separately. Cells treated with zinc showed increased intracellular free zinc concentrations, and this response was significantly enhanced in cells treated with cortisol and zinc. In conclusion, zinc treatment inhibited cortisol-induced cytotoxicity and apoptosis through indirect antioxidant action.

Physician's Duty to Inform Treatment Risk: Function, Requirements and Sanctions (의사의 위험설명의무 - 법적 기능, 요건 및 위반에 대한 제재 -)

  • Lee, Dongjin
    • The Korean Society of Law and Medicine
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    • v.21 no.1
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    • pp.3-32
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    • 2020
  • Under the Korean case law, physicians are obliged to disclose or inform the risk associated with a specific treatment to their patients before they perform the treatment. If they fail to do this, they are liable to compensate pain and sufferings. If the patient can establish that he or she would not have consented at all to the treatment had he or she been informed, the physicians are liable to compensate all the loss incurred by the treatment. In this article, the author examines the legitimacy of this case law from the perspective of legal doctrine as well as its practical affect on the medical practice and the furtherance of self-determination of the patient. The fundamental findings are as follows: The case law that has physicians who failed to inform treatment risk compensate pain and sufferings for the infringement of the right of self-determination seems to be a disguised and reduced compensation of all the loss based on the possible malpractice, which cannot be justified in view of the general principles of tort liability. It is necessary to adhere to the requirements of causation and imputation between the failure to inform treatment risk and the specific patient's consent to the treatment. If this causation and imputation is established, all the loss should be compensated. Otherwise, there shall be no liability. The so-called hypothetical consent defence shall be regarded as a part of causation between the failure to inform and the consent. The suggested approach can preserve the essence of physician-patient relationship and fit for the very logic of informed consent better.

Calibration Examination of Dose Area Product Meters using X-ray (X선을 이용한 면적선량계의 교정 연구)

  • Jung, Jae Eun;Won, Do-Yeon;Jung, Hong-Moon;Kweon, Dae Cheol
    • Journal of the Korean Society of Radiology
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    • v.11 no.1
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    • pp.37-42
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    • 2017
  • We measured the absorbed dose and the area dose using an ionization chamber type of area dose product (DAP) meter and measured the calibration factor in the X-ray examination. In the indirect dose measurement method, the detector was installed in the radiation part of the X-ray equipment, and the measured value was calculated as the dose at the exposure part. The instrument used to calculate the calibration factor was an X-ray equipment (DK-550R / F, DongKang Medical Co., Ltd., Seoul, Korea). The calibration method for the calibration factor was to connect the DAP meter (PD-8100, Toreck Co. Ltd., Japan) to the calibration dosimeter tube voltage of 70 kV, tube current of 500 mA, 0.158 sec. The reference dosimeter used a semiconductor (DOSIMAX plus A, Scanditronix, $Wellh{\ddot{o}}fer$, Germany). After installing the DAP meter on the front of the multi-collimator of the ionization chamber, the calibration factor of the dosimeter was obtained using the reference dosimeter for accurate dose measurement. Experimental exposure values and values from the calibration dosimeter were calculated by multiplying each calibration factor. The calibration factor was calculated as 1.045. In order to calculate the calibration coefficient according to the tube voltage in the ionization type DAP dosimeter, the absorbed dose and the area dose were calculated and the calibration factor was calculated. The corrective area dose was calculated by calculating the calibration factor of the DAP meter.

Analysis of Sedimentation Around Jetties in the West Coast: based on field measurement and hydrodynamic modeling (서해연안 돌제구조물 주위의 침퇴적 해석: 실측 및 수동역학 모델에 의한 초기추정)

  • Suh, Seung-Won;Yoo, Gyeong-Sun;Lee, Hwa-Young
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.19 no.4
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    • pp.345-354
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    • 2007
  • A sedimentation analysis has been attempted to figure out sedimentation environment due to construction of coastal jetties, such as fish harbor dike, flow guided dike and jetty in shallow Kusipo area, in which tidal range marks up to 6.6 meters in spring tide. As an initial approach of understanding field measurement were done on several stations along reference lines with total station and photo analysis taken by remote controlled small air craft far one and half years. Also numerical tests were done by 2-D ADCIRC model considering dry-wet treatment to evaluate flow and bottom shear stress variations. According to direct measurement, deposition seems to be dominant on Kusipo beach. Model results show bottom shear stress lessens to $0.10{\sim}0.15\;N/m^2$ on most shadow zone of jetties and the inner zone is suffering sedimentation as a result of dike construction. However this is the first approach with limited analysis, thus it should be dealt further considering physical characteristics of bottom sediments in a complete sediment model on upcoming study.

Method development for quantitative analysis of naturally occurring radioactive nuclides in building materials (실내 건축자재 중 천연방사성핵종의 정량분석법 연구)

  • Lim, Jong-Myoung;Lee, Hoon;Kim, Chang-Jong;Jang, Mee;Park, Ji-Young;Chung, Kun Ho
    • Analytical Science and Technology
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    • v.30 no.5
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    • pp.252-261
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    • 2017
  • Naturally occurring radioactive materials (NORMs) increase radiation exposure to the public as these materials are concentrated through artificial manufacturing processes by human activities. This study focuses on the development of a method for the quantitative analysis of $^{232}Th$, $^{235}U$, and $^{238}U$ in building materials. The accuracy and precision of inductively coupled plasma mass spectrometry (ICP-MS) for determination of digestion processes was evaluated for certified reference materials (CRMs) digested using various mixed acid (e.g., aqua regia, hydrofluoric acid, and perchloric acid) digestions and a $LiBO_2$ fusion method. The method validation results reveal that a $LiBO_2$ fusion and $Fe(OH)_3$ co-precipitation should be applied as the optimal sample digestion process for the quantitative analysis of radionuclides in building materials. The radioactivity of $^{232}Th$, $^{235}U$, and $^{238}U$ in a total of 51 building material (e.g., board, brick, cement, paint, tile, and wall paper) samples was quantitatively analyzed using an established process. Finally, the values of $^{238}U$ and $^{232}Th$ radioactivity were comprehensively compared with those from the indirect method using ${\gamma}$-spectrometry.

The Effects of Diesel Exhaust Particulates and Particulate Matters on the Airway Remodeling in the Asthma-induced Mice (디젤분진 및 미세분진이 천식마우스에서 기도 재구성에 미치는 효과)

  • Li, Tianzhu;Lee, Soo-Jin;Jang, Yang-Ho;Park, Jun-Hong;Park, Se-Jong;Lee, Jeong-Hak;Choe, Nong-Hoon
    • Journal of Life Science
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    • v.17 no.2 s.82
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    • pp.248-253
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    • 2007
  • This research investigated whether exposure of diesel exhaust particulate (DEP) and particulate matter (PM) effects on airway remodeling in asthma induced Balb/c and IL-10 knock out (KO) mouse. Mice were sensitized with intraperitoneal injection with ovalbumin, followed by challenges with intranasal ovalbumin. After that mice placed in inhalation chamber and exposed to DEP and $PM(10\;mg/m^3)$. The evidence of airway remodeling was assessed by masson's trichrome staining and PAS staining. The stainability of masson's trichrome and PAS reaction were increased in asthma-induced Baltic mice groups compared with control mice groups. More intensive stainability for masson's trichrome and PAS were appeared in the asthma-induced DEP and PM-exposed groups than asthama-induced groups. But, not significantly increased subepithelial fibrosis and the nember of goblet cell hyperplasia in asthma-induced IL-10 KO mice groups and asthma-induced+DEP and PM-exposed IL-10 KO mice than IL-10 KO mice groups. These results indirectly suggesting that exposure to DEP and PM in asthmatic patients might be aggravate clinical symptoms and IL-10 which seems to play a central role in allergic asthma. In conclusion, DEP and PM exposure might have additive effects on the ovalbumin- induced asthma in a murine model.