• The Korean Journal of Nuclear Medicine
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• v.36 no.6
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• pp.368-380
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• 2002

Purpose: Liver transplantation (LT), one of the therapeutic options of primary liver cancer has been suffering from recurrence caused by metastasis in 8-54% of patients. This study was performed to investigate whether FDG-PET is useful for detecting hidden metastasis in LT candidates. Materials and Methods: Twenty-six patients (male:female=23:3, mean age 55.7 years) underwent FDG-PET. Their previous conventional diagnostic studies (CDS) like abdomen US and CT, chest x-ray and CT, and bone scan were negative (n=22) or equivocal (n=4) for metastasis. Positive FDG-PET findings were confirmed by biopsy or clinical follow-up. Results: Among 4 patients with equivocal metastatic lesions on CDS, 3 had 6 hypermetabolic lesions on FDG-PET, which were confirmed as metastasis and subsequently LTs were cancelled. Of these, 5 lesions were initially negative on CDS. Remained 1 patient underwent LT with a negative FDG-PET result. Among 22 patients without metastasis on CDS, 5 had 7 hypermetabolic lesions on FDG-PET. One of these patients proved to have 2 metastatic lesions, and LT was cancelled. The other 4 patients had S hypermetabolic lesions on FDG-PET, which were confirmed as benign lesions, and 3 patients of them underwent LT. In summary, FDG-PET was useful in avoiding 4 unwarranted LT by detecting unsuspected metastatic lesions on CDS. A total of 17 patients underwent LT. In comparison with pathology, the sensitivity and specificity of FDG-PET for detecting viable primary liver cancer were 55.6% (5/9) and 87.5% (7/8), respectively. Conclusion: FDG-PET can detect additional hidden metastasis and contribute to reducing unwarranted LT in the patients with primary liver cancer.

• Journal of Oral Medicine and Pain
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• v.26 no.3
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• pp.225-241
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• 2001

구취에 대한 환자의 주관적 감각은 다양한 심리학적 요소들에 의하여 영향을 받을 가능성이 있다. 본 연구에서는 구취 환자의 심리학적 특징을 살펴보기 위하여, 구취를 주소로 내원한 환자 446명과 일반적인 치과 치료를 위하여 내원한 환자 63명을 대상으로 간이정신진단검사 (SCL-90-R), 구취 설문검사, 구취 측정 검사를 시행하여 분석한 결과 아래와 같은 결론을 얻었다. 1. 남성 구취 환자와 여성 구취 환자의 연령분포는 통계학적으로 유의한 차이를 보였다 (p<0.001). 남성에서는 20대, 30대, 40대에 고르게 분포한 반면, 여성에서는 20대와 30대에 집중되어 분포하였다. 2. 구취의 인식 유형은 남녀간에 통계학적으로 유의한 차이를 보였다 (p<0.01). 구취 인식 유형 중 타인에 의한 지적이나 타인의 행동으로 인한 추측 없이 스스로 구취를 인지하는 유형은 여성 구취 환자에서만 관찰되었다. 3. 구취 환자는 대조군에 비하여 강박증, 불안, 적대감, 전체심도지수에서 높은 수치를 보였다 (p<0.05). 4. 여성 구취 환자는 남성 구취 환자에 비하여 강박증(p<0.05), 불안 (p<0.05), 편집증 (p<0.001)에서 높은 수치를 보였다. 5. 남성 구취 환자에서는 표출증상합계를 (p<0.05) 제외한 모든 간이정신진단검사 항목에서 고농도 VSC군과 저농도 VSC군간에 유의한 차이를 보이지 않았다. 여성 구취 환자에서는 저농도 VSC군이 신체화를 제외한 모든 간이정신진단검사 항목에서 고농도 VSC군에 비하여 높은 수치를 보였다 (p<0.05). 6. 여성 구취 환자에서 주관적 구취심도는 강박증, 대인예민성, 불안, 적대감, 공포불안, 전체심도지수, 표출증상심도지수 들과 유의한 상관관계를 보였고 (p<0.05), 주관적 구취불편감은 모든 간이정신진단검사 항목들과 유의한 상관관계를 보였다 (p<0.05).

• Communications for Statistical Applications and Methods
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• v.15 no.3
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• pp.387-402
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• 2008

In this thesis we propose a two-stage periodic inspection model for maintaining the reliability of a system in long-term storage. There are two types of tests available; a fallible test and an error-free test. The system is overhauled at detection of failure or when the storage reliability after inspection becomes less than or equal to the prespecified value. The expected cost per unit time until overhaul is derived and a procedure for minimizing the expected cost is suggested. The two-stage periodic inspection model is compared with the one-stage periodic inspection model for various parameters of the cost function when the failure time follows exponential and Weibull distributions. The proposed model is then applied to an existing missile system for comparison with the current inspection policy.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.3
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• pp.1228-1233
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• 2013

The purposes of this study were to assess the reliability of the Korean version of Montreal Cognitive Assessment (MoCA-K) and Korean version of Mini-Mental State Examination (MMSE-K) and correlation between MoCA-K and MMSE-K to detect cognitive impairment following stroke determined by a neuropsychological battery. Fifty-two chronic stroke patients participated in this study. They divided two group, normal cognitive group (20 patients) with stroke and cognitive impairment group with stroke (32 patients), and research period was from October 2th. to November 30th., 2013. The subjects were measured K-MoCA and K-MMSE. Normal cognitive group showed the moderate reliability in K-MoCA and K-MMSE. Cognitive group showed the more moderate relaibility in K-MoCA and K-MMSE. There was positive correlation as the more score of K-MoCA gain, the more score of K-MMSE showed in both group. The results suggest that both clinical measures are moderately sensitive and proper feasibility to chronic post-stroke cognitive impairment. The both clinical tools suggest to use in research and clinical settings by a neuropshchological battery.

• Journal of Oral Medicine and Pain
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• v.24 no.4
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• pp.387-396
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• 1999

구취를 주소로 내원한 환자 중 구취의 치료 후 객관적인 구취의 감소가 인정되는 데도 불구하고, 계속해서 구취를 호소하며 만족해 하지 못하는 환자들의 심리적 특성을 알아보고자 하였다. 구취를 주소로 서울대학교 치과병원 구강진단과 구취클리닉에 내원하여 검사 및 치료를 시행한 환자 중, 치료 전 객관적 구취의 소견을 보였으나, 치료 후 할리미터 수치의 객관적인 감소를 보이는 40명의 구취 환자를 대상으로 하였다. 치료 전, 모든 환자들은 자신의 주관적 구취 심도 및 그로 인한 불편감 정도를 표시하였고, 간이정신진단검사 (SCL-90-R)를 시행하였으며 할리미터를 이용하여 구강내 휘발성황화합물의 농도를 측정하였다. 치료 후, 구강내 휘발성황화합물의 농도, 주관적 구취 심도 및 불편감 정도를 재측정하였다. 주관적 구취 심도의 감소 정도에 따라 환자들을 두 군으로 분류하여 할리미터 수치와 불편감 정도 및 간이정신진단검사항목을 비교, 분석하였다; A군-주관적 구취 심도가 평균값 이상으로 감소한 환자군; B군-주관적 구취 심도가 평균값 이하로 감소한 환자군. 1. 치료 전후 모두에서 주관적 구취 심도와 휘발성황화합물 농도 사이에는 유의한 상관관계가 없었으며 주관적 구취 심도의 감소 정도 또한 휘발성황화합물의 감소 정도와 상관관계가 없었다. 2. 치료 전 휘발성황화합물의 농도는 치료 후 휘발성황화합물의 감소치와 유의한 상관관계를 보였다 (p < 0.01). 3.구취로 인한 불편감 정도는 주관적 구취 심도와 유의한 상관관계를 보였으며 (p < 0.01), 치료 후 A군에서는 유의하게 감소 (p < 0.01) 하였으나, B군에서는 유의한 감소를 보이지 않았다. 4. B군은 A군에 비하여 간이정신진단검사 항목 중 대인예민성과 우울증의 항목에서 유의하게 높은 수치를 보였다 (p < 0.05).

• Biomedical Science Letters
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• v.2 no.1
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• pp.49-55
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• 1996

The objective of this study was to develop a paper strip which could determine E. coli qualitatively and quantitatively in water, wastewater, drinks, or food. This paper strip method was a simple and rapid test method that determine E. coli by visual identification. In this study, nutrient culture media were formulated and characterized for optimum conditions. Paper strips were then prepared by impregnating into the media and dried at $60^\circ$C. The test procedure is quite simple to use. The paper strip was dipped into a sample, and excess sample was removed. The strip was then incubated at $37^\circ$C for 16 to 20 hours and the number of colonies on the strip was counted. The color of the colony spots produced by microorganisms varied depending on the media formulation. Violet-red spots were produced by E. coli. The test method was simple, rapid and no special laboratory equipment was necessary for visual identification. Therefore, this test method is applicable to on-site tests such as field tests or home tests. The paper strip method was compared with the standard agar plate method and Japanese commercial product. The method of the economical preparation of test strips was studied for production on industrial scale.

• Korean Journal of Clinical Laboratory Science
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• v.49 no.2
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• pp.108-113
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• 2017

A sudden cardiac death (SCD) is defined as an unnatural sudden death caused by heart disease. To determine the cause of death, observation of the microscopic change in cardiac muscle tissue is suggested, rather than visual postmortem examination. However, this suggestion is time consuming to be applied in the field, is cost-ineffective, and is inconvenient. Therefore, the purpose of this study is to understand whether temporary inspection used to examine the cardiac marker (Myoglobin, CK-MB, cTn I) in postmortem blood via rapid cardiac triple test kit (which is used by clinics to diagnose patients with acute myocardial infarction) can effectively be utilized for the paragnosis of sudden, unnatural cardiac death. The results of postmortem examination and temporary investigation found that 23 groups (76.7%), among the 30 experimental groups, were assumed to be non-traumatic sudden cardiac deaths, which indicated a positive response (according to comparison with forensic autopsy); 4 groups, among the 10 control groups, were assumed to be cerebrovascular disease, which indicated a negative response; 1 group was assumed to be alcoholic and drug poisoning, indicating a positive response; and 1 group was assumed to be oxygen deficiency due to suffocation, indicating a positive response. Hence, it was found that the level of sensitivity and specificity of cardiac marker's temporary inspection showed significant result, 76.7% and 80% respectively. Given this, temporary inspection can be effectively used for the paragnosis of sudden cardiac death when the medical history, situation of the site, and postmortem interval are considered together. With the result of precedent research on time of first revelation and extinction in blood, and difference in concentration over time progress according to the characteristic of cardiac marker's (myoglobin, CK-MB, cTn I) individual material, further research on concentration of cardiac marker per each post time needs to be conducted in order to estimate time science death (which is required to identify the cause of death and investigation).

• Korea journal of population studies
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• v.27 no.2
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• pp.231-255
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• 2004

본 연구의 목적은 경상북도 경산지역에 거주하는 65세 이상 노인들의 치매실태를 알아보고 치매노인들의 인구학적 특성 및 생활 습관적 특성을 알아보는데 있다. 본 연구에서는 모집단의 약 6%에 해당하는 1,120 명을 표본으로 추출하여 한국형 간이정신상태 검사를 포함한 면담표를 이용하여 2003년 8월 1일부터 2003년 9월 2l일까지 수행되었다. 면담에 응하지 않거나 분석 자료로 활용할 수 없는 160 사례를 제외한 960 사례가 최종분석에 이용되었다. 본 연구에서 밝혀진 내용은 다음과 같다. 한국형 간이정신상태 검사에 따르면 응답자들의 10.6%가 치매에 이환된 것으로 나타났으며 그들 가운데 54.9%는 경증, 31.4%는 중등증, 13.7%는 중증이었다. 치매노인들의 인구학적 및 생활 습관적 특성을 알아보기 위하여 교차분석을 도입하였으며 치매에 영향을 미치는 인구학적 및 생활 습관적 특성들을 경험적으로 규명하기 위하여 로지스틱회귀분석을 사용하였다. 로지스틱회귀분석 결과 정신노동에 관련된 직업에 종사했던, 규칙적인 운동을 하는 응답자, 규칙적 식사를 하는 사람과 적당량의 음식을 섭취하는 응답자들이 치매이환의 대수승산을 감소시키는 것으로 밝혀졌으며 통계적으로 유의미한 것으로 나타났다. 반면 나이가 높을수록 노인들의 치매이환의 대수승산을 증가시키는 것으로 밝혀졌다. 끝으로 노인들의 치매이환을 감소시키기 위한 여러 가지 정책적 대안들을 논의하였다.

• The Journal of the Korea Contents Association
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• v.9 no.9
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• pp.287-294
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• 2009

The purpose of this research is to test the relationship between ACLT(Allen Cognitive Level Test) and FIM(Functional Independence Measure), MMSE-K(Mini-Mental State Examination), and MFT(Manual Function Test). 38 elderly persons with stroke were recruited. Pearson Correlation Coefficients is used for correlation test. There is statistically significant correlation between ACLT and FIM, MMSE-K, and MFT(p<.05). This results identified the relationship between cognitive function and activities of daily living, indicated the usability of ACLT as a cognition assessment tool and the need of research for it's application in stroke patients.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.32 no.3
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• pp.256-260
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• 1999

Minimun-detectable levels to 28 antibacterial agents used for the prevention and the treatment of fish diseases were determined to establish optimal detective method of bioassay in fish by the EEC 4-plate method, the modified method of EEC 4-plate and the standard method of analysis in food safety regulation. The test organisms used in the methods of bioassay were as follows: Bacillus subtilis BGA (B. subtilis) and Micrococcus luteus ATCC 9341 (M. luteus) in the EEC 4-plate method, B. subtilis, M. luteus and Bacillus cereus var. mycoides ATCC 11778 (B. cereus) in the modified of EEC 4-plate, and B. subtilis, M. luteus, B. cereus and Bacillus stearothermophilis var. calidolactis C-953 (B. stearothermophilis) in the standard method. The standard method showed predominant sensitivity in the detection of penicillins (PCs), and was also highly sensitive to aminoglycosides (AGs). The sensitivity of standard method in the detection of tetracyclines (TCs), marrolides (MLs), nitrofuran derivatives(NFs) and quinolones (QNs) was very low, and against sulfonamides (SAs), however, was extremely low. The modified method of EEC 4-plate showed very high sensitivity to TCs. Both the EEC 4-plate and the modified method of EEC 4-plate showed competitively high sensitivity in the detection of PCs, MLs, NFs, QNs and SAs. All the methods studied in the experiment showed very low sensitivity against chloramphenicol (CMs). Consequently, the modified method of EEC 4-Plate was the best bioassay method with a wide range of sensitivity for the optimal detection of the residual antibacterial agents in fish.