• Journal of Korean Ophthalmic Optics Society
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• v.9 no.2
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• pp.281-290
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• 2004

The purpose of this study is to investigate the correlation between the central corneal thickness and peripheral one, and the changing aspect of corneal thickness by the refractive error through the measure of central corneal thickness and peripheral one in myopic eyes. For this study, the central thickness and the peripheral one of the 198 eyes of 99 normal subjects was measured by Orbscan Topography System(Orbtex, Inc. USA). The latter was measured in each 2mm point distance of superior, inferior, nasal and temporal from the center of left & right eye. And the revealed results was analyzed according to sex, age, left & right eyes, and refractive error of the subjects. The mean central corneal thickness of the whole subjects was shown as $530.12{\pm}43.18{\mu}m$, and the mean peripheral ones were as follows : superior(SCT) $591.91{\pm}36.88{\mu}m$, inferior(ICT) $561.04{\pm}41.82{\mu}m$, nasal(NCT) $584.23{\pm}41.97{\mu}m$ and temporal(TCT) $567.35{\pm}43.25{\mu}m$. From this, we can see that the mean central corneal thickness and the peripheral ones show significantly difference, but there is no statistically Significant difference in the corneal thickness according to refractive error, age, sex, and left & right.

• Journal of Korean Ophthalmic Optics Society
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• v.14 no.3
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• pp.7-15
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• 2009

Purpose: To investigate the corneal recovery after discontinuing orthokeratology (OK) lenses wear in children for long-term period. Methods: Among the OK lens wearers who wear over 8 months and showed successful refractive correction, 25 subjects were selected who want to discontinue the OK lenses. Uncorrected visual acuity, refractive correction, corneal curvature (Sim K), central corneal thickness and corneal eccentricity were measured during the OK lens wearing period and after discontinuation for 1 month. Results: Uncorrected visual acuity and corneal shape had remodeled significantly during the OK lens wear and recovered significantly during the first week of discontinuation. Uncorrected visual acuity and refractive correction had achieved full recovery 2 weeks after discontinuation of lens wear and were highly correlated with the changes in corneal thickness. But corneal shape recovered slowly, eccentricity had recovered fully after 1 month and corneal curvature and central thickness had not been achieved full recovery until 1 month after discontinuation. Conclusions: Recovery of after longterm use of OK lens is rapid for refractive change, but slow for corneal curvature and central thickness that to refit the contact lenses, practitioners need patience.

• Journal of Korean Ophthalmic Optics Society
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• v.12 no.4
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• pp.29-35
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• 2007

This study was conducted to measure the central corneal thickness(CTT) changes associated with kinds of wearing contact lens. The CCT was measured using ultrasonic pachymeter in three hundred four subjects in their 20s and 30s. Although the CCT of Group 1 who had never worn any kinds of contact lens had no differences between left and right eye as well as between genders, the CCT tended to become thinner depending on the increment in refractive error. In Group 2 wearing only soft contact lens, the CCT was thinner depending on wearing period, and subjects wearing for more than 10 years had significantly thin CCT comparing with subjects wearing for less than 4 years. There was no significant difference in the CCT between Group 3 wearing only RGP lens and Group 2 for less than 4 years. Furthermore, when comparing the CCT between the Group 2 and Group 4 changing to RGP lens after wearing soft contact lens, there was no statistically significant change in the CCT. However, the CCT was significantly thinner in Group 5 changing to soft contact lens after wearing PMMA(polymethyl methacrylate) hard lens compared with Group 2.

• Journal of Korean Ophthalmic Optics Society
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• v.13 no.1
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• pp.89-94
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• 2008

Purpose: To make a comparative study of correlation between biometry data of size in eyeball and refractive error. Methods: The subjects were 68 normal university students (male 36, female 32) and the average age was 22.85${\pm}$3.12. We measured the students' eyesight by A-scan ultrasound and refractor. The results were examined it's statistical significance by SPSS 12.0 version. Results: The mean of axial length was 24.31${\pm}$1.24 mm, chamber depth was 3.48${\pm}$0.28 mm, lens thickness was 3.56${\pm}$0.26 mm and corneal thickness was 0.55${\pm}$0.03 mm. Male's Axial length and chamber depth were larger than female's. As reflective error decreases the thickness of lens become thicker. The measurement data between right eye and left eye didn't had difference and there was no correlation with result of T-test. There were statistically significant correlation with length and chamber depth, axial length and corneal thickness, chamber depth and corneal thickness, and refractive error and lens thickness (p<0.01). Refractive error and axial length were minus linear regression (r=-0.56). Conclusions: Eye's refractive error was changed by axial length, chamber depth and lens thickness but it wasn't related with sex and whether it is a right eye or a left eye.

• Journal of Korean Ophthalmic Optics Society
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• v.13 no.3
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• pp.35-43
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• 2008

Purpose: This review article was written to investigate how the various factors, such as lacrimal thickness, CL's thickness and Dk, affects the influx of $O_2$ diffusion into the cornea. Methods: A mathematical model was proposed to analyze the oxygen diffusion reaching the cornea through the tear layers and contact lens based on Fick's law and the principle of continuity of the diffusion flux through the each layers. Results: The model predicts how the parameters such as the thickness of tear layer on the cornea, both the Dk and thickness of contact lenses etc., affect the oxygen tension at cornea and oxygen flux entering the cornea. Conclusions: It is found that either too flat or too tightly fitted contact lenses can cause the oxygen deficiency at/inside the periphery of the cornea because of the reduction of oxygen flux resulted from too thickened tear layer.

• Journal of Korean Ophthalmic Optics Society
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• v.19 no.1
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• pp.111-120
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• 2014

Purpose: This study was to investigate changes in the thickness of cornea, curvature of cornea, and aberration depending on the water contents, materials, and refractive power of contact lens. Methods: The differences in the corneal thickness between pre- and post-wearing the lenses were compared using 5 kinds of lenses. The changes in the corneal thickness, the curvatures of the anterior and posterior cornea, and high order aberration (HOA) before and after wearing the lenses were investigated at the center of the cornea, and the different distance and the direction away from the center of the cornea. For the equipments of measurement, ORB ScanII (Bausch & Lomb Inc, ver 3.14) was used to measure the corneal topography and thickness, and Zywave (Bausch & Lomb Inc, ver 5.20) was used to analyze the high order aberration. Results: Five (S1, S2, S3, T1, T2) of the lens was used for this study, excluding the lens T2 lens has four lenses and the thickness of the corneal shape, but the impact is minimal. In the case of the hydrogel soft contact lenses (T2 lens) with low oxygen permeability, the corneal thickness showed distinct increasing patterns. The high order aberration and coma aberration were most changed in the silicon hydrogel toric lens, while the depth of anterior was most changed in the hydrogel toric lens. Conclusion: Among the 5 kinds of contact lenses with different water contents, materials, and refractive power used for this study, the corneal shape change was small for the lenses with an oxygen permeability (Dk) of more than 28, and the largest for the lenses with a very low oxygen permeability.

• Journal of Korean Ophthalmic Optics Society
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• v.16 no.1
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• pp.97-106
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• 2011

Purpose: This review article was written to theoretically compare the depressing force (pressure, adhesion) to the cornea between when the spherical lenses were being tightly and flat fitted. Methods: Mathematical equations and their numerical solution programs (model) were formulated to calculate the depressing (adhesion) force to the cornea by both the tightly and flat fitted contact lenses. Based on this proposed model the effects of parameters characterizing a contact lens such as BCs, diameters, edge shape and corneal shape (ratio of long and short corneal axis, p) on the depressing force to the cornea were predicted/analyzed in both tightly and flat fitting regimes. Results: Corneal adhesion increased as the corneal p-value increased. Adhesion increase caused by the increased p-value was much larger in flat fitted case than in tight fitted one. Corneal adhesion reduced abruptly as the BC increased in flat fitting regimes while the adhesion rise was insignificant in tight fitting ones. Reduction in corneal adhesion due to lens-size increase was predicted to be insignificant in both tight and flat fitting regimes. Both the lens edge shape (edge angle) and thickness were relevant only in tight fitting regime. Corneal adhesion increased as the increased with tight-fitted lenses. As the thickness of tight fitted lenses increased, corneal adhesion inversely decreased. Conclusions: The two most significantly affecting the depressing force to cornea were found to be the degree of corneal bending toward the periphery and the BCs of lenses.

• Journal of Korean Ophthalmic Optics Society
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• v.17 no.2
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• pp.223-232
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• 2012

Purpose: Validating a new research method to determine posterior corneal curvature and asphericity(Q) in vivo, based on measurements of anterior corneal topography and corneal thickness. Methods: Anterior corneal topographic data, derived from the Medmont E300 corneal topographer, and total corneal thickness data measured along the horizontal corneal meridian using the Holden-Payor optical pachometer, were used to calculate the anterior and posterior corneal apical radii of curvature and Q. To calculate accurate total corneal thickness the local radius of anterior corneal curvature, and an exact solution for the relationship between real and apparent thickness were taken into consideration. This method differs from previous approach. An elliptical curve for anterior and posterior cornea were calculated by using best fit algorism of the anterior corneal topographic data and derived coordinates of the posterior cornea respectively. For validation of the calculations of the posterior corneal topography, ten polymethyl methacrylate (PMMA) lenses and right eyes of five adult subjects were examined. Results: The mean absolute accuracy (${\pm}$standard deviation(SD)) of calculated posterior apical radius and Q of ten PMMA lenses was $0.053{\pm}0.044mm$ (95% confidence interval (CI) -0.033 to 0.139), and $0.10{\pm}0.10$ (95% CI -0.10 to 0.31) respectively. The mean absolute repeatability coefficient (${\pm}SD$) of the calculated posterior apical radius and Q of five human eyes was $0.07{\pm}0.06mm$ (95% CI -0.05 to 0.19) and $0.09{\pm}0.07$ (95% CI -0.05 to 0.23), respectively. Conclusions: The result shows that acceptable accuracy in calculations of posterior apical radius and Q was achieved. This new method shows promise for application to the living human cornea.

• Journal of Korean Ophthalmic Optics Society
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• v.8 no.2
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• pp.1-11
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• 2003

A mathematical model was proposed to analyze the oxygen diffusion reaching the cornea through the tear layers and contact lens based on Fick's law and the principle of continuity of the diffusion flux through the each layers. The model predicts how the parameters such as the thickness of tear layer on the cornea, both the Dk and thickness of contact lenses etc., affect the oxygen tension at cornea and oxygen flux entering the cornea. It is found that either too flat or too tightly fitted contact lenses can cause the oxygen deficiency inside the periphery of the cornea because of the reduction of oxygen flux resulted from too thickened tear layer.

• Journal of Korean Ophthalmic Optics Society
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• v.13 no.4
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• pp.65-73
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• 2008

Purpose: The purpose of this study is to investigate the effect of age in the response to long-term overnight orthokeratology (OK) lens wearing. Methods: Among volunteers, ninety-five healthy subjects who had no eye diseases and could wear OK contact lens at least for 8 hours every day were divided into three groups children, youngsters and young adults. Unaided logMAR visual acuity, refractive error, apical corneal radius, corneal asphericity and central corneal thickness were measured with different period; before and after one day, one week, two weeks, one month, three months and six months of OK lens wear. Paired student t-test, ANOVA analysis and Pearson correlation were used with a critical p value of 0.05 for statistical analysis. Results: All groups showed statistically significant (p<0.001) improvement in unaided visual acuity, a trend for flattening in the apical corneal radius, decrease in central corneal thickness and less prolate after OK lens wear. The child group showed significantly rapid change (p<0.001) in visual acuity, and apical corneal radius showed that they reached the targeted refractive change earlier compared with youngster and adult groups. The visual effect of OK lens was significantly related with the change in central corneal thickness after long-term OK lens wear, especially in child and youngster group, and central corneal thickness were highly correlated with the targeted refractive change. Conclusions: Visual acuity change is statistically correlated with the central corneal thickness change, which is highly correlated with targeted refractive change in the long-term orthokeratology and younger lens wearers showed a rapid response to OK lens wear, suggesting a reduced epithelial response with increasing age. The results found this study extends our understanding and development in the long-term orthokeratology.