• Title/Summary/Keyword: 가공모델

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Electrospraying of Micro/Nano Particles for Protein Drug Delivery (단백질 약물 전달을 위한 마이크로/나노 입자의 전기분무 제조법)

  • Yoo, Ji-Youn;Kim, Min-Young;Lee, Jong-Hwi
    • Polymer(Korea)
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    • v.31 no.3
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    • pp.215-220
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    • 2007
  • The control of the surface energy by electrohydrodynamic force provides electrospraying with various potential advantages such as simple particle size control, mono-dispersity, high recovery, and mild processing conditions. The advantages are quite helpful to improve the stability of protein drug and control its release. Herein, the nano-encapsulation of protein drugs using electrospraying was investigated. Albumin as a model protein was processed using uniaxial and co-axial electrospraying, and chitosan, polycaporlactone (PCL), and poly (ethylene glycol) (PEG) were used as encapsulation materials. The major processing parameters such as the conductivity of spraying liquids, flow rate, the distance of electrical potential gradient, etc were measured to obtain the maximum efficiency. In the chitosan systems, mean particles size decreases as flow rate and the distance between nozzle and the collecting part decreases. In the uniaxial technique of the PCL systems, mean particles size decreases as flow rate decreases. In the coaxial technique of the PCL systems, it was found that the particles size gets larger under the application of the higher ratio of inner-to-outer liquid flow rates. The primary particles formed out of an electrospraying nozzle showed narrow particle size distribution, but once they arrived to the collecting part, aggregation behavior was observed obviously. Efficient nano-encapsulation of albumin with PCL, PEG, and chitosan was conveniently achieved using electrospraying at above 12 kV.

가스치환포장 및 감마선을 병용처리한 최소가공 절임배추의 품질특성

  • 안현주;김재현;김재경;조철훈;김장호;육홍선;변명우
    • Proceedings of the Korean Society of Postharvest Science and Technology of Agricultural Products Conference
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    • 2003.10a
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    • pp.185.2-186
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    • 2003
  • 세계적으로 최소가공식품(minimally processed foods)의 시장이 확대되면서, 최소가공된 과채류의 미생물학적 안전성 확보가 중요한 사안으로 대두되고 있다. 이에 본 연구는 김치제조용 원료배추를 모델로 하여 감마선 및 가스치환 포장법을 병용한 절임배추의 미생물학적, 이화학적 특성을 평가하였다. Fresh-cut상태의 절임배추(염농도 3%)를 각각 air, 100% $CO_2$, 25% $CO_2$/75% $N_2$가스를 주입하여 포장한 후 0, 0.5, 1, 2 kGy의 선량으로 감마선 조사하여 3주 동안 저장하면서 분석에 사용하였다. Total aerobic bacteria, coliforms, Salmonella, lactic acid bacteria의 분포를 살펴본 결과, $CO_2$혹은 $CO_2$/$N_2$포장과 감마선을 병용처리한 경우 저장기간 동안 total aerobic bacteria, coliforms 및 Salmonella 모두 1kGy의 선량에서 90% 이상 감소시킬 수 있는 것으로 나타나, 일반 함기포장보다 효과적인 것으로 나타났다. 색도 및 물성은 포장방법에 따른 차이를 보이지 않았으며, pH의 경우도 감마선 조사 및 가스치환 포장시 더욱 효과적으로 유지할 수 있었다. FRAP(ferric reducing antioxidant power) value 및 DPPH radical 소거능과 같은 생리활성 능력을 측정한 결과 포장방법 및 감마선 조사에 의한 차이를 보이지 않았다. 따라서 가스치환 포장 및 감마선 조사를 병용시 함기포장구 보다 낮은 감마선 조사선 량에서 병원성 미생물을 제어할 수 있었으며, 이화학적 품질이 우수하고 저장성이 향상된 절임배추를 제조할 수 있었다.7로 4$0^{\circ}C$ 진공건조와 -7$0^{\circ}C$ 동결건조의 L값 변화보다 큰 변화를 보였고, 또한‘a’값과 ‘b’값의 경우도 마찬가지로 5$0^{\circ}C$ 열풍건조의 경우가 양파의 내부와 외부면의 적색도 및 황색도 변화가 크게 일어나는 경향을 나타내었다. 건조과정 중 vitamin C의 함량변화는 건조에 의한 수분함량의 감소로 vitamin C의 함량은 상대적으로 증가하였고, -7$0^{\circ}C$ 동결건조의 경우가 가장 높은 vitamin C의 증가량을 나타내었고, 그와 반대로 5$0^{\circ}C$ 열풍건조의 경우는 열에 의한 vitamin C의 변화로 인한 상대적 증가량은 감소하는 경향을 나타내었다.아현미가 더욱 조밀하였다. 10시간 탈삽처리에서 상품성이 우수하였다. 그러나 25'E 28시간 탈삽처리는 탈삽의 균일도가 다른 처리에 비해 떨어지는 경향이었다. 경우, 사과표피의 색도 변화를 현저히 지연시킴을 확인하였다. 또한 control과 비교하여 성공적으로 사과에 코팅하였으며, 상온에서 보관하여을 때 사과의 품질을 30일 이상 연장하는 효과를 관찰하였다. 이들 결과로부터 대두단백질 필름이 과일 등의 포장제로서 이용할 가능성을 확인하였다.로 [-wh] 겹의문사는 복수 의미를 지닐 수 없 다. 그러면 단수 의미는 어떻게 생성되는가\ulcorner 본 논문에서는 표면적 형태에도 불구하고 [-wh]의미의 겹의문사는 병렬적 관계의 합성어가 아니라 내부구조를 지니지 않은 단순한 단어(minimal $X^{0}$ elements)로 가정한다. 즉, [+wh] 의미의 겹의문사는 동일한 구성요 소를 지닌 병렬적 합성어([$[W1]_{XO-}$ $[W

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A Mechanical Information Model of Line Heating Process using Artificial Neural Network (인공신경망을 이용한 선상가열 공정의 역학정보모델)

  • Park, Sung-Gun;Kim, Won-Don;Shin, Jong-Gye
    • Journal of the Society of Naval Architects of Korea
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    • v.34 no.1
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    • pp.122-129
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    • 1997
  • Thermo-elastic-plastic analyses used in solving plate forming process are often computationally expensive. To obtain an optimal process of line heating typically requires numerous iterations between the simulation and a finite element analysis. This process often becomes prohibitive due to the amount of computer time required for numerical simulation of line heating process. Therefore, a new techniques that could significantly reduce the computer time required to solve a complex analysis problem would be beneficial. In this paper, we considered factors that influence the bending effect by line heating and developed inference engine by using the concept of artificial neural network. To verify the validity of the neural network, we used results obtained from numerical analysis. We trained the neural network with the data made from numerical analysis and experiments varying the structure of neural network, in other words varying the number of hidden layers and the number of neurons in each hidden layers. From that we concluded that if the number of neurons in each hidden layers is large enough neural network having two hidden layers can be trained easily and errors between exact value and results obtained from trained network are not so large. Consequently, if there are enough number of training pairs, artificial neural network can infer similar results. Based on the numerical results, we applied the artificial neural network technique to deal with mechanical behavior of line heating at simulation stage effectively.

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Roll Force Prediction of High-Strength Steel Using Foil Rolling Theory in Cold Skin Pass Rolling (고강도강의 냉간 조질 압연 시 호일 압연이론을 이용한 압연하중의 예측)

  • Song, Gil Ho;Jung, Jae Chook
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.37 no.2
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    • pp.271-277
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    • 2013
  • Skin pass rolling is a very important process for applying a certain elongation to a strip in the cold rolling and annealing processes, which play an important role in preventing the stretching of the yield point when the material is processed. The exact prediction of the rolling force is essential for obtaining a given elongation with the steel grade and strip size. Unlike hot rolling and cold rolling, skin pass rolling is used to apply an elongation of within 2% to the strip. Under a small reduction, it is difficult to predict the rolling force because the elastic deformation behavior of the rolls is complicated and a model for predicting the rolling force has not yet been established. Nevertheless, the exact prediction of the rolling force in skin pass rolling has gained increasing importance in recent times with the rapid development of high-strength steels for use in automobiles. In this study, the possibility of predicting the rolling force in skin pass rolling for producing various steel grades was examined using foil rolling theory, which is known to have similar elastic deformation behavior of rolls in the roll bite. It was found that a noncircular arc model is more accurate than a circular model in predicting the roll force of high-strength steel below TS 980 MPa in skin pass rolling.

A Model-Fitting Approach of External Force on Electric Pole Using Generalized Additive Model (일반화 가법 모형을 이용한 전주 외력 모델링)

  • Park, Chul Young;Shin, Chang Sun;Park, Myung Hye;Lee, Seung Bae;Park, Jang Woo
    • KIPS Transactions on Computer and Communication Systems
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    • v.6 no.11
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    • pp.445-452
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    • 2017
  • Electric pole is a supporting beam used for power transmission/distribution which accelerometer are used for measuring a external force. The meteorological condition has various effects on the external forces of electric pole. One of them is the elasticity change of the aerial wire. It is very important to perform modelling. The acceleration sensor is converted into a pitch and a roll angle. The meteorological condition has a high correlation between variables, and selecting significant explanatory variables for modeling may result in the problem of over-fitting. We constructed high deviance explained model considering multicollinearity using the Generalized Additive Model which is one of the machine learning methods. As a result of the Variation Inflation Factor Test, we selected and fitted the significant variable as temperature, precipitation, wind speed, wind direction, air pressure, dewpoint, hours of daylight and cloud cover. It was noted that the Hours of daylight, cloud cover and air pressure has high explained value in explonatory variable. The average coefficient of determination (R-Squared) of the Generalized Additive Model was 0.69. The constructed model can help to predict the influence on the external forces of electric pole, and contribute to the purpose of securing safety on utility pole.

Web and Building Information Model-based Visualization of Indoor Environment -Focusing on the Data of Temperature, Humidity and Dust Density- (웹 및 건물정보모델기반 실내 환경 디지털 시각화 -온습도와 미세먼지 농도 데이터를 중심으로-)

  • Huang, Jin-hua;Lee, Jin-Kook;Jeon, Gyu-yeob
    • The Journal of the Korea Contents Association
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    • v.17 no.2
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    • pp.327-336
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    • 2017
  • People spend most of their time in the indoor environment. Among the various indoor environmental factors, air and thermal environment directly affect human's health and efficiency of work. Therefore, efficient monitoring of indoor environment is highly important. For assisting the residents to understand the state of the indoor environment much easier and more intuitive, this paper analyze the visualization cases of the conventional indoor environment. Then explore the direction of improvement for the visualization method to propose a more effective visualization method. The approach of web and BIM(Building Information Model)-based visualization of indoor environment proposed in this study is composed of four major parts: 1) the generation of the model data of the building; 2) the generation of indoor environmental data; 3) the creation of visualization elements; 4) data mapping. Then it realized through the generating process of visualization results.

A Determination Model of the Data Transmission-Interval for Collecting Vehicular Information at WAVE-technology driven Highway by Simulation Method (모의실험을 이용한 WAVE기반 고속도로 차량정보 전송간격 결정 모델 연구)

  • Jang, Jeong-Ah;Cho, Han-Byeog;Kim, Hyon-Suk
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.9 no.4
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    • pp.1-12
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    • 2010
  • This paper deals with the transmission interval of vehicle data in smart highway where WAVE (Wireless Access for Vehicular Environments) systems have been installed for advanced road infrastructure. The vehicle data could be collected at every second, which is containing location information of the vehicle as well the vehicle speed, RPM, fuel consuming and safety data. The safety data such as DTC code, can be collected through OBD-II. These vehicle data can be used for valuable contents for processing and providing traffic information. In this paper, we propose a model to decide the collection interval of vehicle information in real time environment. This model can change the transmission interval along with special and time-variant traffic condition based on the 32 scenarios using microscopic traffic simulator, VISSIM. We have reviewed the transmission interval, communication transmission quantity and communication interval, tried to confirm about communication possibility and BPS, etc for each scenario. As results, in 2-lane from 1km highway segment, most appropriate transmission interval is 2 times over spatial basic segment considering to communication specification. In the future, if a variety of wireless technologies on the road is introduced, this paper considering not only traffic condition but also wireless network specification will be utilized the high value.

Development of an Activity-Based Conceptual Cost Estimating Model for P.S.CBox Girder Bridge (대표공종 기반의 P.S.C 박스 거더교 개략공사비 산정모델 개발 -상부공사 중심으로-)

  • Cho, Ji-Hoon;Kim, Sang-Bum
    • Proceedings of the Korean Institute Of Construction Engineering and Management
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    • 2008.11a
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    • pp.197-201
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    • 2008
  • Conceptual cost estimates for domestic highway projects have generally been conducted using governmental unit-price references. Inaccuracies in governmental unit-price data has repeatedly addressed in the Korean construction industry which often lead to poor decision making and cost management practices. Thus, needs for developing a better way of conceptual cost estimating has been widely recognized. This research is considered as the first step in developing such model using real-world cost data based on actual construction activities. The data analyzed in this paper includes 41 P.S.C (Prestressed Concrete) Box bridges which broke into 4 categories based on construction methods such as I.L.M(Incremental Launching Method), M.S.S(Movable Scaffolding System), F.S.M(Full Staging Method), and F.C.M(Free Cantilever Method). Actual design documents; including actual cost estimating documents, drawings and specifications were carefully reviewed to effectively break down cost structures for PSC girder bridges. Among more than 40 cost categories for each P.S.C girder bridge type, 7 of them were identified which accounted for more than 95% of total construction cost (ILM: 99.47%, MSS: 99.22%, FSM: 98.18%, and FCM: 98.12%). In order to validate the clustering of cost categories, the variation of each cost category has been investigated which resulted in between -1.16 % and 0.59%.

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Prediction of Distillation Column Temperature Using Machine Learning and Data Preprocessing (머신 러닝과 데이터 전처리를 활용한 증류탑 온도 예측)

  • Lee, Yechan;Choi, Yeongryeol;Cho, Hyungtae;Kim, Junghwan
    • Korean Chemical Engineering Research
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    • v.59 no.2
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    • pp.191-199
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    • 2021
  • A distillation column, which is a main facility of the chemical process, separates the desired product from a mixture by using the difference of boiling points. The distillation process requires the optimization and the prediction of operation because it consumes much energy. The target process of this study is difficult to operate efficiently because the composition of feed flow is not steady according to the supplier. To deal with this problem, we could develop a data-driven model to predict operating conditions. However, data preprocessing is essential to improve the predictive performance of the model because the raw data contains outlier and noise. In this study, after optimizing the predictive model based long-short term memory (LSTM) and Random forest (RF), we used a low-pass filter and one-class support vector machine for data preprocessing and compared predictive performance according to the method and range of the preprocessing. The performance of the predictive model and the effect of the preprocessing is compared by using R2 and RMSE. In the case of LSTM, R2 increased from 0.791 to 0.977 by 23.5%, and RMSE decreased from 0.132 to 0.029 by 78.0%. In the case of RF, R2 increased from 0.767 to 0.938 by 22.3%, and RMSE decreased from 0.140 to 0.050 by 64.3%.

A Study on the Compensation Methods of Object Recognition Errors for Using Intelligent Recognition Model in Sports Games (스포츠 경기에서 지능인식모델을 이용하기 위한 대상체 인식오류 보상방법에 관한 연구)

  • Han, Junsu;Kim, Jongwon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.5
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    • pp.537-542
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    • 2021
  • This paper improves the possibility of recognizing fast-moving objects through the YOLO (You Only Look Once) deep learning recognition model in an application environment for object recognition in images. The purpose was to study the method of collecting semantic data through processing. In the recognition model, the moving object recognition error was identified as unrecognized because of the difference between the frame rate of the camera and the moving speed of the object and a misrecognition due to the existence of a similar object in an environment adjacent to the object. To minimize the recognition errors by compensating for errors, such as unrecognized and misrecognized objects through the proposed data collection method, and applying vision processing technology for the causes of errors that may occur in images acquired for sports (tennis games) that can represent real similar environments. The effectiveness of effective secondary data collection was improved by research on methods and processing structures. Therefore, by applying the data collection method proposed in this study, ordinary people can collect and manage data to improve their health and athletic performance in the sports and health industry through the simple shooting of a smart-phone camera.