• Journal of Nutrition and Health
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• v.40 no.3
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• pp.242-248
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• 2007

It is known that onion increases antioxidative and antibiotic capacity, and decreases blood pressure and cholesterol levels. The study was carried out to investigate whether ethanol extract of onion can enhance blood lipid profiles in hypercholesterolemic patients. Foully three hypercholesterolemic patients were randomly divided into 2 groups; 25 in controls and 18 in experimental group. The control group was offered to take placebo for 4 weeks (200 ml/day), and experimental group was offered to consume ethanol extract of onion for 8 weeks (200 ml/day that corresponds to 500 g of onion). There were no differences in sex, age, body mass index (BMI) and educational levels between groups before treatment. After 8 weeks of onion extract consumption, plasma triglycerides level was significantly decreased in experimental group compared to control (p<0.05). Total cholesterol level was tended to decrease in experimental group, but there was no significant difference of change between control and experimental group. The levels of plasma glucose and LDL-cholesterol were not changed significantly after onion extract consumption. In summary, alcohol extract of onion may have a positive effect on the lipid profiles of hypercholesterolemia patients through decreasing plasma triglyceride concentration.

• Journal of Oral Medicine and Pain
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• v.26 no.4
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• pp.319-329
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• 2001

Endothelin-1 (ET-1) is a recently discovered potent vasoconstrictive peptide. It was first identified in vascular endothelial cells. ET-1 is a 21-amino acid peptide and elicits systemic effects such as stimulation of the production of atrial natriuretic peptide and release of aldosterone and corticosterone. In this study, to examine the role of ET-1 in the bone metabolism, effect of ET-1 on the proliferation and activity of osteoblastic cells was studied using HOS cells as osteoblast model. ET-1 dose-dependently increased the cell proliferation as determined by cell counting and MTT reduction assay after 48hr treatment. Alkaline phosphatase activity was inhibited by ET-1 and showed significant inhibition by 50 and 100 nM ET-1. ET-1 increased NBT reduction by HOS cells dose-dependently showing that ET-1 may increase the superoxide production by osteoblasts. Nitrite concentration in the media of HOS cell culture without cytokine stimulation was negligible and unaffected by ET-1 after 48hr treatment. Finally, after collection and concentration of conditioned media, gelatinase activity produced by HOS cells was determined by zymography. HOS cells can produce and secrete the gelatinase (gelatinase A type as determined by molecular weight of about 65,000) into culture media, however, ET-1 had no effect on the gelatinase activity. These findings suggest that ET-1 may have diverse effects on the proliferation and differentiation of osteoblasts, therefore, it may play an important role in bone metabolism.

• Journal of Navigation and Port Research
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• v.32 no.3
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• pp.229-235
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• 2008

This paper was provided to apply the ITC-Hulls Clauses & ISM Code for the accident of sunken ship which was occurred by seamen's barratry. For the causes of the sunken accident, the underwriter insisted toot shipowner submerged the vessel intentionally for the purpose of the insured amounts, while shipowner protests toot the ship was submerged because of crews faults. In this connection, the judge sentenced toot this accident was caused by humans errors as the Provisions of 6.2.4 of ITC-Hulls, however shipowner is responsible for hiring onboard qualified seafarers and carrying out the due diligence for performing ISM Code for ensuring ship's safety and seaworthiness.

• Korean Journal of Biological Psychiatry
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• v.7 no.1
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• pp.99-106
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• 2000

Background : In spite of relative high risk of extrapyramidal side effect and tardive dyskinesia, it is common clinical practice to use antipyschotics in treatment of bipolar I disorder. But in Korea, there has been few study about clinical factors related with antipsychotics treatment in bipolar disorder patients. So the author studied about the clinical factors related with antipsychotics treatment in bipolar inpatients focusing on the comparison of risperidone and classical antipsychotics. Method : By reviewing medical record retrospectively, datas about patient-related, illness-related, and treatment-related clinical factors on antipsychotics use were collected. Association between antipsychotics dose and duration and clinical factors were analysed by statistical method. Results : Aggressive behavior was only statistically significant factor associated with antipsychotics use. And in the case of aggression, maintenance dose of risperidone was not changed(p=0.84), but dose of classical antipsychotics was increased significantly(p=0.005). Total hospital days and antipsychotics treatment duration showed no difference between risperidone and classical antipsychotics treatment groups. Conclusion : Clinical factors associated with antipsychotics use was aggressive behavior. In the case of aggression, risperidone required lesser dose increment compared with classical antipsychotics.

• Journal of computational fluids engineering
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• v.18 no.1
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• pp.58-62
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• 2013

Personal Rapid Transit (PRT) is the emerging personal transport vehicle operating on the loop automatically. The PRT system utilize the electrical power from super capacity or battery, it is important to manage the power or energy. In this regards, the management of high temperature occurred by the operation of system is significantly important to prevent from serious damage of component. In this study, we studied the adequate shape of underbody which can reduce the heat accumulation by pickup coil and condenser using natural air cooling. We suggested the additional air pathway, air inlet and flow separator to decrease the temperature of the heat source components. It was found that suggested system can decrease the temperature of PRT under body by 16% during the static mode and by 10% during the running mode at 30km/h. It is expected that the findings of this study will feed into final design of newly built Korean PRT vehicle.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.24 no.12
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• pp.1580-1587
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• 2000

Rayleigh scattering and laser induced predissociative fluorescence are employed for capturing two-dimensional images of temperature and species concentration in a laminar nonpremixed flame of a diluted hydrogen jet. Rayleigh scattering cross-sections are experimentally obtained ar 248nm. Dispersed LIPF spectra of OH and O$_2$ are also measured in a flame in order to confirm the excitation of single vibronic state of OH and O$_2$ .OH and O$_2$ are excited on the P$_1$(8) line of the A $^2\Sigma ^+(v^`=3) - X^2\pi (V^"=0)$ band and R(17) line of the Schumann-Runge band B $^3\Sigma _u^-(v^`=0) - X ^3\Sigma _g^-(v^"=6)$, respectively. Fluorescence spectra of OH and Hot O$_2$ are captured and two-dimensional images of the hydrogen flame field are successfully visualized.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.36 no.8
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• pp.797-802
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• 2012

In this study, the potential performance enhancement in a dual heat pump system through series operation was investigated by a comparison between the performance for parallel and series operation for a heating supply temperature of $60^{\circ}C$. To compare the performance of each configuration fairly, the heat transfer surface area of the heat exchangers was fixed. The inlet temperatures and the flow rates of the heat source and the load were also fixed. In addition, the heat transfer and pressure drop characteristics of the working fluids were considered to achieve a more realistic comparison. The results show that the heating coefficient of performance (COP) of the series configuration is approximately 5% higher than that of the parallel configuration under the simulation conditions considered in the present study.

• Proceedings of the Korean Vacuum Society Conference
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• 2014.02a
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• pp.468-468
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• 2014

우리나라는 미국, EU, 러시아, 중국, 인도 등 다국간 협력 사업인 국제핵융합실험로(ITER) 사업에 참여하고 있으며, 블랑켓 일차벽 및 시험용 블랑켓 모듈(Test Blanket Module, TBM) 제작기술 개발에 필요한 고열부하 검증시험을 국내에서 자체적으로 실시하기 위한 고열부하시험 시설을 구축하였다. 한국원자력연구원에 설치된 고열부하시험 시설의 주요 사양은 다음과 같다. 열원으로는 전자빔을 사용하며, 빔출력은 최대 300 kW이고, 최대 출력밀도는 $10GW/m^2$이다. 전자빔의 최대 가속전압은 60 kV이고, 최대 조사 면적은 설계상 $70cm{\times}50cm$이다. 고열부하 장비는 핵융합환경과 유사한 고열부하를 시험대상물에 인가하여 접합 및 냉각 성능을 평가하는 장비이며, ITER 블랑켓 및 TBM 일차벽의 경우 약 $0.5MW/m^2$, 가속실험 혹은 사고 시 순간 시나리오 해석을 위해서 $5MW/m^2$까지 고려되기도 한다. ITER 블랑켓 일차벽 제작기술 개발 및 검증(2004~2011)에서는 외국장비(러시아 TSEFEY, 일본 JEBIS, 독일 JUDITH)를 활용하였으나, 고비용 문제와 장비 이용 시간의 제한에 따라 사용이 어려워, 국내에서는 KoHLT-1, 2 장비를 자체 구축하여 활용하여 왔다. 현재는 높은 열부하 인가조건, 약 $5MW/m^2$을 달성하기 위해서 전자빔을 이용한 고열부하시험 장치를 마련하였으며, ITER 블랑켓 일차벽 Semi-Prototype 검증시험, TBM, KSTAR 디버터 실험 등 핵융합로 일차벽 개발에 활용하고 있다. 전자빔, 전원 및 진공 chamber 등 전체 고열부하 시험장치를 구축하여 ITER 장치를 포함해서 토카막 디버터 등 핵융합 플라즈마 대면부품 (Plasma Facing Components, PFC) 재료 개발과 국방, 항공우주 분야의 열유속 게이지 측정법 향상 연구, 로켓 추진 엔진 연소실의 열유속 모니터링 연구, 항공기 프로펠러 연구 등에 활용할 수 있을 것으로 기대된다.

• Proceedings of the Korean Vacuum Society Conference
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• 2014.02a
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• pp.289.1-289.1
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• 2014

In this study, we made a organic thin film device in MIS(Metal-Insulator-Semiconductor) structure by using PVP (Poly vinyl phenol) as a insulating layer, and CdSe/ZnS nano particles which have a core/shell structure inside. We dissolved PVP and PMF in PGMEA, organic solvent, then formed a thin film through a spin coating. After that, it was cross-linked by annealing for 1 hour in a vacuum oven at $185^{\circ}C$. We operated FTIR measurement to check this, and discovered the amount of absorption reduced in the wave-length region near 3400 cm-1, so could observe decrease of -OH. Boonton7200 was used to measure a C-V relationship to confirm a properties of the nano particles, and as a result, the width of the memory window increased when device including nano particles. Additionally, we used HP4145B in order to make sure the electrical characteristics of the organic thin film device and analyzed a conduction mechanism of the device by measuring I-V relationship. When the voltage was low, FNT occurred chiefly, but as the voltage increased, Schottky Emission occurred mainly. We synthesized CdSe/ZnS and to confirm this, took a picture of Si substrate including nano particles with SEM. Spherical quantum dots were properly made. Due to this study, we realized there is high possibility of application of next generation memory device using organic thin film device and nano particles, and we expect more researches about this issue would be done.

• Korean Journal of Materials Research
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• v.9 no.2
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• pp.149-154
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• 1999

Alumina substrate was sealed by PbO-ZnO-$B_2O_3$glass using microwave heating. The crystallization behaviour of sealing glass and the state of sealing joint were investigated and were compared with those of conventionally sealed one. Compared to the conventional one, the microwave heat-treated sample had well-grown $\textrm{PbTiO}_3$ crystals and high degree of crystallinity even though it had shorter heat-treatment time and lower heat-treatment temperature. Also, the microwave sealed sample exhibited relatively a good sealing state and almost same bending strength.