• 동의생리병리학회지
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• 제20권4호
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• pp.1057-1062
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• 2006

In order to research the interrelationship of symptoms of 5 visceral diseases through Pearson's correlative coefficient and to understand the diagnostic importances of each symptom and sexual differences in the main symptoms of each visceral diseases using Cronbach alpha. For this 500 female and 120 male cases of questionnaire were collected and analyzed. In the main symptoms of 5 visceral diseases, there were a little differences between this results and existing symptom-complex system. And in the comparison of most frequently manifesting symptoms to male and female subject, Heart and Pancreas and Kidney disease were almost same, but Liver disease was different and Lung disease was slightly different. Conclusively, the diagnostic reliability of the abstracted symptom-complex of 5 viscera was graded from Kidney(Cronbach alpha 0.8771555), Pancreas(0.865978), Liver(0.815013), Heart(0.78653) to Lung disease(0.6294695) sequentially. And the each Cronbach alpha was valuable to be permitted as diagnostic criteria of 5 visceral diseases.

• 대한한의학원전학회지
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• 제20권3호
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• pp.49-56
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• 2007

The "Somun Jogyongron(素問 調經論)" describes excess and deficiency syndromes. The study suggests that excess syndrome(實證) is caused by vigorous pathogenic fire(火邪)(the spirit(神)), pathogenic dryness(燥邪)(Gi(氣)), pathogenic wind(風邪)(blood(血)), pathogenic dampness(濕邪)(physique(形)) or pathogenic coldness(寒邪)(will(志)). When pathogenic fire is dominant within the body, Gi and blood becomes excessive and come out of the body, but the body cannot take them back, leading to the symptom in which the patient cannot stop laughing. When pathogenic dryness prevails, the lung(肺) cannot function properly. This means that the convergence(收斂) function of the clearing the lung and descending Gi(肅降) is deteriorated, and the patient shows symptoms of dyspnea and cough. Strong pathogenic wind increases the ascencling Gi in the liver(肝氣) and fuel angry emotion when the patient becomes upset. When pathogenic dampness is dominant, spleen(脾) function drops due to lumping effects, and the patient will experience abdominal distention(腹脹), which will disturb urination and defecation. When pathogenic coldness prevails, abdominal distention occurs due to condensating effects, and Yang Gj(陽氣) in the kidney(腎) is disturbed, leading to digestion disorders and eventually water-grain dysentery. Deficiency syndrome is caused by the lack of essential Gi(精氣) in the five viscera(五藏). Deficiency of sprit means the lack of Gi in the heart(心氣), so the patient becomes vulnerable to sadness. Deficiency of Gi means the lack of Gi in the lung(肺氣), so the patient may have breathing disorders. Deficiency of blood means the lack of Gi in the Liver(肝氣), so the patient can be easily scared. Deficiency of physique means the lack of Gi in the spleen(脾氣), making it difficult to use arms and legs. Deficiency of will means the lack of Gi in the kidney(腎氣), so Gowl syndrome(厥證) can ensue.

• 대한수의학회지
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• 제12권1호
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• pp.25-35
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• 1972

견(犬)의 전좌폐(全左肺) 또는 좌폐하엽(左肺下葉)을 고무 낭(囊)으로 반복호흡(反覆呼吸)(rebreathing)을 연속(連續)시키며 폐동맥(肺動脈)(혼합정맥혈액(混合靜脈血液)) 및 폐정맥(肺靜脈)의 혈중탄산(血中炭酸)gas와 산소(酸素)를 반복호흡(反覆呼吸)한 폐포(肺胞)의 탄산(炭酸)gas 및 산소(酸素)와 비교(比較)하였다. 이들 두 기체(氣體)에 있어서 폐포(肺胞) gas의 장력(張力)이 혈액(血液) gas의 장력(張力)보다 항상 컸으며, 또 폐포(肺胞)와 폐동맥간(肺動脈間)의 경사도(傾斜度)가 폐포(肺胞)와 폐정맥간(肺靜脈間)의 경사도(傾斜度)보다 컸으나 탄산(炭酸) gas에 있어서만 유의성(有意性)이 있었다. 이 결과는 폐조직(肺組織)의 대사과정(代謝過程)에 의(依)하여 탄산(炭酸) gas가 생성(生成)되어 혈류(血流)로 운반(運搬)되어지기 때문이라 생각된다. 폐포(肺胞)와 폐정맥간(肺靜脈間)의 경사도(傾斜度)가 감소(減少)될때 폐동맥(肺動脈)과 폐정맥(肺靜脈)의 탄산(炭酸)gas장력(張力)의 차이(差異)는 증가(增加)하였고 마취심도(麻醉深度)와는 무간(無間)하였다. 본실험(本實驗)에서 반복호흡(反覆呼吸)을 하는 폐내(肺內)의 혐기성대사(嫌氣性代謝)(anaerobic metabolism)로 대사성산(代謝性酸)의 생성(生成)에 의(依)하여 폐(肺)를 통과(通過)한 혈액중(血液中) base exces 감소(減少)를 예측(豫測)할수 있었으나 그러한 증거(證據)는 없었다.

• 대한한의학원전학회지
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• 제12권2호
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• pp.176-183
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• 1999

Each life has its own properties that distinguish one another. With this property, Oriental medicine suggests original diagnosis and treament. Our process of aging shows typical outline of cycle, i. e. from one's birth to death. Understanding the life cycle of men gives us very good hint to predict one's state of health, possible diseases, characteristics of disease in each term of his/her life cycle. It's because body and mode of diseases change according to age. Aging starts when $\breve{U}$m Essence(陰精)-the essence one receive from parents-dries up or when Deficient Fire(虛火) soars. Parts that compose our body-bones, muscles, flesh, etc.-gradually weaken and worn out as they no longer get support from Yang-Ki(陽氣), In "Yellow Emperor's Classic", aging starts around one's forties when $\breve{U}$m Essence(陰精) is reduced to less than half. However, what is usually accepted is that women start aging from 49 and men 64, regarding significant geriatric disease. As it is mentioned, aging starts with exhaustion of $\breve{U}$m Essence(陰精) which results in soaring Deficient Fire. Main symptoms are weak mental state due to Sin(神) disorder, and weak physical state due to Spleen and Stomacn(脾胃) disorder. Main principle in treating and preventing diseases related to aging is preserving $\breve{U}$m Essence(陰精), as well as fortifying Ki and Blood(氣血). To do this, Lung(肺)-which collects $\breve{U}$m Essence(陰精), and Kidney(腎) stores-which stores $\breve{U}$m Essence(陰精).

• 혜화의학회지
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• 제8권1호
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• pp.643-657
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• 1999

Through observing effect of BOPEASAN(BPT) on an aging white rat's metabolic enzyme system, the following conclusions were addressed 1. The quantity of the lipid peroxide in lung of was decreased meaningfully in all of experimental subject groups, relatively to counterpart groups. 2. Cytochrome P-450, Cytochrome b5, NADPH-Cytochrome P45, was decreased meaningfully in the experimental subject groups B,C and D. 3. superoxide dismutase, catarase, grutathione peroxidase, was increased meaningfully in the experimental subject groups B.C and D. 4. glutathione, glutathione S-transferase, glutathione redutase, ${\gamma}$-Glutamylcytein synthetase, had no meaningful change in the experimental subject groups. Regarding the above conclusions, the Bopeasan was affecting positively on both lipid peroxide a nd the enzyme system, as well as it has efficacy of suppressing the phenomena of aging, Therefore, the Bopeasan is, hereafter, expected to be applied clinically.

• 한방안이비인후피부과학회지
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• 제23권1호
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• pp.282-288
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• 2010

In our review, the conclusions on the concept and principle of perspiration are as follows. 1. It is the physiological perspiration that Qingyang(淸陽) from Jing(精), Qi(氣), Xie(血) synthesized by digestion of food and drink(水穀), is increased and secreted from pores on the skin(腠理). 2. The main center to control perspiration is heart(心), but lver(肝), stomach(胃), spleen(脾), lung(肺), bladder(膀胱), kidney(腎) and triple energizer(三焦) can be also related to perspiration indirectly. 3. As Weiqi(衛氣) make the body warm and keep the body temperature constant by controlling perspiration, it is very important to make a diagnosis of Weiqi(衛氣) Xushi(虛實) by skin temperature. 4. We guess that perspiration can be secreted by the control of BiaoLi-YinYang(表裏陰陽) such as centrifugal(氣) and centrifetal force(形) of Qi(氣). 5. Sweating therapy can make the level of Biaoyang(表陽) correct and control the balance between centrifugal(氣) and centrifetal force(形) of Qi(氣).

• 대한한방내과학회지
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• 제18권1호
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• pp.255-269
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• 1997

This study has been carried out to investigate the cause, pathological mechanism and treatment of CVA in Youmunsachin(儒門事親), written by Changjongjung(張從政) The results were follows : 1. The cause of CVA in Youmunsachin(儒門事親) was quotated from the theory of Naekyung(內經), Guel-eum-pung-mok(厥陰風木) and exogenous wind evil(外感風邪) on weakness of human body. 2. The pathological mechenism of CVA was that flows of Ki(氣) were obstructive, or executive heart(心) suppress lung(肺) and weakened lung(金) did not control liver(肝), executive liver brought to Gan-pung-nae-dong(肝風內動), and he thought that onset of CVA was frequent in 3nd, 4th, 9th. 10th, 12th lunar month. 3. In treatment of CVA, Han-to-ha-bub(汗吐不法, sweating vomiting passing stool method to remove evil) was used. His treatment was divided into ten sweating vomiting passing stool method by medication for internal use, one vomiting method by medication for external use and one sweating method by using acupuncture. 4. In treatment of CVA, when emergency time, vomiting and passing stool method were used, and then, method of Yangheulgeopung(養血祛風), Chungeulgeodam(淸熱去痰), Pyorissanghae(表裏雙解), Whalheultonglak(活血通絡) was used. 5. In the form of prescription, he used the form of Hwan, San(丸, 散), and he used toxic agent frequently.

• 대한수의학회지
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• 제6권1호
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• pp.57-75
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• 1966

This study was conducted to observe the condition of the ramifications of the bronchus and pulmonary blood vascular system by injecting the vinylite into the bronchial tree and pulmonary blood vessels in 100 normal adult dogs. The results obtained were summarized as follows: 1. Lungs of dog were composed of the same pulmonary territories as in lungs of human. 2. Cardiac lobe corresponding to R.medio-bassalis of human lungs was well developed and situated as a independent cardiac lobe, in ventral side of right lung. 3. Bronchial tree were in the patterns of axial divergency and blood vascular systems were (in general) branched along the bronchial tree, arteries lying near the bronchial tree but veins apart from it. 4. Among the branching patterns of bronchus pulmonary artery and pulmonary vein in each lobe, the type presented most frequently were noted, which were designated basic type by the author. 5. Pulmonary blood vessels were not always branched in accordance with bronchial tree, diverged inmore complex patterns, especially in venous vascular system. 6. Ramus anterior (lobe apicalis) was always observed in all casting specimen. 7. There was a case of peculiar variation patterns of the ramification in the bronchi directing into the left apical and cardiac lobe, arose respectivelly, at independent origin of bifurcation in the left bronchial stem, and a case of peculiar variation pattern of the artery entering left apical lobe and cardiac lobe, had a same origin of the bifurcation at rami pulmonary artery, and then divided respectivelly into the rami medi artery and rami left apical lobe artery. 8. In the classification based on the patterns of bronchial and blood vasculor divergencys, there were a lot of significant combination cases in their patterns.

• 한방안이비인후피부과학회지
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• 제18권3호
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• pp.1-17
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• 2005

In many recent studies, molecular biological methods have been used to investigate the role of cytokines in pathogenesis of lung disease. This Experiment was conducted to investigate the effects of Sochungyong-tang on gene expressions in Mouse Alveolar Macrophage. Fer this purpose, we observed the cytokines ($IL-1{\beta}$, IL-6, IL-10, iNOS, $MIP-1{\alpha},\;MIP-1{\beta},\;MIP-1{\gamma},\;TGF-{\beta},\;TNF-{\alpha}$). We picked the alveolar macrophage out of mice and cultured it. We analyzed the cytokine gene expression by reverse transcription-PCR. The results obtained were as follows : 1 . Sochungyong-tang showed inhibitory effects on $IL-1{\beta}$ in time and concentration. 2. Sochungyong-tang showed inhibitory effects on IL-6 in time and concentration. 3. Sochungyong-tang showed inhibitory effects on IL-10 in concentration. 4. Sochungyong-tang showed inhibitory effects on iNOS. 5. Sochungyong-tang showed inhibitory effects on $TGF-{\beta}$ in time and concentration. 6. Sochungyong-tang showed on inhibitory effects on $MIP-1{\alpha},\;MIP-1{\beta},\;MIP-1{\gamma}$, $TCF-{\beta}$, $TNF-{\alpha}$. According to above results, it is supposed that Sochungyong-tang has the inhibitory effects on cytokine gene expression in mouse alveolar macrophage and can be usefully applied for curing inflammatory process of lung disease. Advanced studies are required to investigate the cure mechanism of Sochungyong-tang in the future.

• 동의생리병리학회지
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• 제23권1호
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• pp.245-250
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• 2009

The purpose of this study is to evaluate the difference about pathogenesis of normal person and traffic accident, author used DSOM to investigate pathogenesis. Patient group is consisted of people who one month does not pass from traffic accident, and normal group is consisted of people who do not have special symptoms and past history. DSOM was used for pathogenesis investigation of two group. There was significant difference between T.A. group and Normal group in deficiency of blood (血虛), stagnation of qi(氣滯), blood stasis(瘀血), dampness(濕), dryness(燥), liver (肝), heart(心), kidney(賢), phlegm(痰)(p<0.05). When it comes to comparison of sex, there was significant difference between male and female in dryness(燥), spleen(脾), and lung(肺)(p<0.05) in T.A. group. But in normal group, there was not significant difference between male and female, and in the case of male there was significant difference between T.A. group and normal group in deficiency of blood(血虛), stagnation of qi(氣滯), kidney(賢), phlegm(痰)(p<0.05). Also in the case of female there was significant difference between T.A. group and normal group in blood(血虛), stagnation of qi(氣滯), blood stasis(瘀血), dampness(濕), dryness(燥), kidney(賢), phlegm(痰)(p<0.05). This result showed that the pathogenesis are differs. This result showed that the pathogenesis of traffic accident patient and normal people are difference.