• 한국식품과학회지
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• 제30권5호
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• pp.1197-1202
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• 1998

폐기되는 난각으로부터 칼슘성분을 회수하여 재활용하는 방안으로서 유기산 난각칼슘염을 제조하고 생면에 첨가하여 첨가량에 따른 반죽특성, 조리성질에 미치는 영향과 숙면의 물성을 조사하였다. 칼슘염을 밀가루에 $0.2{\sim}1.0%$ 첨가하여 흡수율, 반죽형성기간, 안정도 등의 반죽 성질에 미치는 영향을 Farinograph로 조사한 결과 전반적으로 calcium malate (CM)의 경우가 calcium citrate (CC)의 경우보다 크게 영향을 미치고 있음을 알 수 있었다. 반죽의 특성에 크게 영향을 주지 않는 범위의 첨가량은 CM의 경우 0.1% 이하이고 CC의 경우는 약 0.4%이었다. 칼슘염을 첨가하여 생면을 제조하였을 때 제조된 숙면의 조리시 부피 증가 속도는 첨가량이 증가함에 따라서 감소하였으며 이 경향은 CM 첨가시가 CC 첨가시 보다 더욱 뚜렷하게 나타났다. 숙면의 관능검사 결과 칼슘염을 0.6% 첨가시 CC의 경우 5% 수준에서 무첨가 생면간에 유의적인 차이가 인정되었으나, CM의 경우는 유의적인 차이가 없었다. 이는 CC의 경우 0.6% 이상 첨가시 springiness가 급격히 증가하였으며 그 증가폭도 CM 첨가의 경우보다 컸던 점과 잘 일치하였다. 한편 반죽 특성과 숙면의 texture, 관능검사로부터 얻어진 최적 첨가량인 CC 0.4%를 첨가한 경우의 칼슘이온농도는 48 ppm으로 무첨가시의 16 ppm의 약 3배에 해당하였다. 이를 200 g의 숙면으로부터 얻어진 칼슘으로 환산한 값은 86 mg이었으며 이온화율은 97.4%이었다.

• 한국농공학회논문집
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• 제58권2호
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• pp.1-9
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• 2016

This study aims to assess the effectiveness of activated carbon (AC) and crushed concrete (CC) as capping material to block the release of nitrogen, phosphorus, and organic substance from reservoir sediments. The efficiency of AC and CC as capping material was evaluated in a reactor in which a 1 or 3 cm thick layer of capping materials was placed on the sediments collected from Mansu reservoir in Anseong-city. Dissolved oxygen (DO) concentration, total nitrogen (T-N), total phosphorus (T-P), and chemical oxygen demand (COD) concentration in reservoir water above the uncapped sediments and capping material were monitored for 45 days. The release rate of T-N was in the following increasing order: AC 3 cm ($1.18mg/m^2{\cdot}d$) < CC 1 cm ($2.66mg/m^2{\cdot}d$) < AC 1 cm ($2.94mg/m^2{\cdot}d$) < CC 3 cm ($3.42mg/m^2{\cdot}d$) < uncapped ($4.59mg/m^2{\cdot}d$). The release rate of T-P was in the following increasing order: AC 3 cm ($0mg/m^2{\cdot}d$) $${\approx_-}$$ CC 3 cm ($0mg/m^2{\cdot}d$) < CC 1 cm ($0.03mg/m^2{\cdot}d$) < AC 1 cm capped ($0.07mg/m^2{\cdot}d$) < uncapped ($0.24mg/m^2{\cdot}d$). The release of nitrogen and phosphorus were effectively blocked by AC capping of 3 cm thickness, and CC capping of 3 cm thickness effectively controlled the release of phosphorus. The order of increasing COD release rate was as follows: AC 3 cm ($0mg/m^2{\cdot}d$) $${\approx_-}$$ CC 3 cm ($0mg/m^2{\cdot}d$) < CC 1 cm ($5.03mg/m^2{\cdot}d$) < AC 1 cm ($7.28mg/m^2{\cdot}d$) < uncapped ($10.05mg/m^2{\cdot}d$), indicating that AC and CC capping effectively interrupted the release of organic contaminants from the sediments. It was concluded that AC and CC could effectively block the release of T-N, T-P and COD release from contaminated reservoir sediments.

• 한국동물위생학회지
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• 제37권1호
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• pp.51-58
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• 2014

The aim of the study was to investigate the anti-obesity effect of Coprinus comatus (CC) in high-fat diet-fed Zucker rat (fa/fa). Obesity was induced by feeding on high-fat diet (HFD) containing 60% kcal fat for 10 weeks, in which CC extracts were administrated through the gastrointestinal tract at a concentration of 200 mg/kg BW/day for 10 weeks. The total polyphenol and flavonoid contents of CC extracts were found to be $18.5{\pm}1.1mg$ of catechin equivalent/g, and $5.24{\pm}0.54mg$ of quercetin equivalent/g extract, respectively. The DPPH, ABTS, and hydroxyl radical scavenging activities of CC extracts were 15.34 %, 17.25%, and 16.18%, respectively. In animal study, CC administration significantly reduced the body weight, while there were no significant differences in the daily food intake between the HFD-fed Zucker rats and HFD plus CC-fed rats. CC treatment decreased epididymal and perirenal fat weights in HFD-fed Zucker rats. Significant decreases in the levels of triglyceride and total cholesterol in the serum and liver were observed in the CC-treated group compared with HFD-fed Zucker rats. Serum HDL-cholesterol levels in the CC-treated group were increased compared with the HFD-fed groups. Serum AST and ALT activities in the CC group were significantly lower than those of the HFD-fed group. Taken together, these data demonstrated that CC has potential in preventing high-fat diet induced obesity and is a good candidate for an anti-obesity agent.

• 농업과학연구
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• 제38권1호
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• pp.17-23
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• 2011

This research was conducted to investigate the influence of application rate of liming fertilizers on changes in soil chemical properties and growth of 'Red Madness' petunia in plug production. To achieve this, dolomite (DO) with 0, 1.0, 3.5, 8.0 or 13.0 $g{\cdot}L^{-1}$ and calcium carbonate (CC) with 0, 2.0, 2.5, 3.0, 3.5, or 4.0 $g{\cdot}L^{-1}$ were incorporated into peatmoss + vermiculite (1:1, v/v) during the root substrates formulation. The treatments of 3.5 $g{\cdot}L^{-1}$ of DO and 2.5 or 3.0 $gL^{-1}$ of CC had acceptable ranges of pH and EC in soil solution such as 5.6~6.2 and 0.7~1.0 $dS{\cdot}m^{-1}$, respectively. The faster rising of pH was observed in root media containing CC rather than those of DO. This indicates that the solubility of CC is higher than DO. The soil Ca concentrations in all treatments of CC were 1.8 times as high as those of DO. The treatments of 3.5 or 8.0 $g{\cdot}L^{-1}$ of DO had the highest soil Mg concentrations, but all treatments of CC had lower soil Mg concentrations than control treatment indicating that additional application of Mg fertilizers are required. The elevated application rate of DO or CC resulted in the increase of fresh and dry weight. But plant heights were not influenced by application of liming fertilizers. The results of tissue analysis showed that application of DO or CC influenced the $PO_4{^-}P$, Ca and Mg contents, but not influenced the contents of other nutrients such as N, P, Fe, Mn, Zn and Cu.

• Journal of Korean Neurosurgical Society
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• 제38권5호
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• pp.359-365
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• 2005

Objective : The study investigates the extent of brain shift and its effect on the accuracy of the stereotaxic procedure. Methods : Thirty-five patients underwent 40stereotactic procedures between June 2002 and March 2004. There were 26 males, mean age 59years old. There were 34procedures for Parkinson's disease, 2 for essential tremor, 3 for cerebral palsy, 1 for dystonia. Patients were divided in four groups based on postoperative pneumocephalus : under 5cc [9 procedures], between $5{\sim}10cc$ [13procedures], between $10{\sim}15cc$ [11 procedures] and more than 15cc [7procedures]. The coordinates of the anterior commissure[AC], posterior commissure[PC], and target were defined in pre-and intraoperative magnetic resonance image scans and the amount of air volume was measured with @Target (BrainLab, Heimstetten, Germany]. Results : The mean AC-PC was 26.5mm for patients with less than 5cc, 26.9mm for $5{\sim}10cc$, 25.8mm for $10{\sim}15cc$ and 26.2mm for more than 15cc. The length of AC-PC line and coordinates of AC, PC was also not statistically different, Euclidean distance as well as ${\Delta}x$, ${\Delta}y$, ${\Delta}z$ of AC, PC, and target were also not statistically different among the groups [p>,1]. There was a variance in target of $0.7{\sim}7.6mm$, Euclidean distance of 2.5mm, related to electrophysiology but not to brain-shift. Conclusion : The amount of air accumulated in the intracranial space and compressing the cortical surface has no effect on the localization of subcortical stereotactic target and landmarks.

• The Korean Journal of Physiology and Pharmacology
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• 제20권3호
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• pp.297-304
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• 2016

Klotho functions as a tumor suppressor predominantly expressed in renal tubular cells, the origin of clear cell renal cell carcinoma (ccRCC). Altered expression and/or activity of growth factor receptor have been implicated in ccRCC development. Although Klotho suppresses a tumor progression through growth factor receptor signaling including insulin-like growth factor-1 receptor (IGF-1R), the role of Klotho acting on IGF-1R in ccRCC and its clinical relevance remains obscure. Here, we show that Klotho is favorable prognostic factor for ccRCC and exerts tumor suppressive role for ccRCC through inhibiting IGF-1R signaling. Our data shows the following key findings. First, in tumor tissues, the level of Klotho and IGF-1R expression are low or high, respectively, compared to that of adjacent non-neoplastic parenchyma. Second, the Klotho expression is clearly low in higher grade of ccRCC and is closely associated with clinical outcomes in tumor progression. Third, Klotho suppresses IGF-1-stimulated cell proliferation and migration by inhibiting PI3K/Akt pathway. These results provide compelling evidence supporting that Klotho acting on IGF-1R signaling functions as tumor suppressor in ccRCC and suggest that Klotho is a potential carcinostatis substance for ccRCC.

• Asian Pacific Journal of Cancer Prevention
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• 제14권1호
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• pp.315-320
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• 2013

Background: TGF-${\beta}$-activated kinase-1 (TAK1) has been found to be over-expressed in a variety of solid malignancies and related to tumor growth. The aim of this study was to evaluate the expression level of TAK1 in clear cell renal cell carcinoma (ccRCC) and assess its value as a novel prognostic marker. Methods: TAK1 mRNA was assessed in 51 paired ccRCC tissues and adjacent normal tissues (ADTs) by real-time PCR. Tissue TAK1 protein was also assessed in 91 ADTs and 177 samples of ccRCC immunohistochemically for evaluation of relationships with clinical characteristics. Results: RT-PCR showed that TAK1 RNA level was significantly higher in ccRCC tissues than in the paired ADTs and immunohistochemistry confirmed higher expression of TAK1 protein in ccRCC samples compared with ADTs. TAK1 protein expression in 177 ccRCC samples was significantly correlated with T stage, N classification, metastasis, recurrence and Fuhrman grade, but not age and gender. Patients with low TAK1 levels had a better survival outcome. TAK1 expression and N stage were independent prognosis factors for the overall survival of ccRCC patients. Conclusions: Overexpression of TAK1 predicts a poor prognosis in patients with ccRCC, so that TAK1 may serve as a novel prognostic marker.

• 대한전기학회논문지:시스템및제어부문D
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• 제51권11호
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• pp.521-527
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• 2002

The Hemodialysis system is the device for the patients who have suffered from end stage renal failure as the kidney which removes the waste products in a human body. The existing hemodialysis is based on a 8-bit micro-controller and it is not a touch-screen type but a manual type. This paper is focused on hemodialysis system based on high control and expension embedded system. The whole system consists of main control unit and sub control unit(dialysis control unit, blood control unit, monitoring control unit, networking unit). The dialysis control unit, blood control unit, monitoring control unit are processed by 3 microcontrollers and network unit is for monitoring a renal failure patient's condition. For the evaluation of the system performance, the saline was pured into blood unit and then water removal rate, conductivity and temperature of hemodialysis liquid were measured 10 times in an each state suing the UF pump in the fluid unit varing the quantity of saline to 1000cc, 2000cc, 3000cc and 4000cc. As a result, the rates of water removal are 98.6% in condition of 000cc saline, 96.9% in 2000cc, 98.9% in 3000cc and 98.3% in 4000cc. The conductivities of hemodialysis liquid are 99.6% in the first to third condition and 99.7% in the forth condition. The temperatures of hemodialysis liquid are 99.8% in the first to third condition and 99.6% in th forth condition.

• 한국정보과학회논문지:시스템및이론
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• 제29권9호
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• pp.503-513
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• 2002

CC-NUMA구조에서는 원격 메모리에 대한 접근이 불가피한 구조적인 특성 때문에 상호 연결망이 성능을 좌우하는 큰 변수로 작용한다. 기존에 사용되는 버스는 대역폭의 한계와 물리적 확장성 때문에 대규모의 시스템에는 적합하지 않다. 이를 대체하는 고속의 지점간 링크를 도입한 이중 링 구조는 이러한 버스의 한계를 극복하고는 있지만 많은 노드를 거쳐야 하는 문제로 인해 응답 지연 시간이 증가하는 단점을 안고 있다. 본 논문에서는 요청과 응답 패킷의 지연 시간을 줄이는 방안으로 리피터 노드를 이용한 다중 링을 제안한다. 제안된 시스템은 링과 링 사이의 구조가 대칭형을 이루고 있어 요청을 내보내는 링을 제외한 다른 링의 hop수는 똑같은 수치를 갖고 있으며, 이중 링에 비해 최대의 hop수와 최소의 hop수의 차가 적고 평균 hop수 또한 적어 좋은 성능을 보인다. 본 논문에서는 또한 이러한 구조를 유지하기 위한 리피터 노드의 구조를 제안하며 리피터 노드의 구조와 노드의 확장에 따른 다양한 성능을 확률 구동 시뮬레이터를 사용하여 평가를 수행한다.

• 한국식품조리과학회지
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• 제23권2호통권98호
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• pp.261-269
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• 2007

This study was performed to provide basic data for the sous vide cook-chill(SVCC) System by comparing and evaluating food quality, according to preparation method and days of storage, of foods that were prepared by SVCC to those prepared using the cook-chill(CC) System. Boiled quail eggs and fish paste in soy sauce were prepared using CC and SVCC and their quality was evaluated at the time of preparation and by days of storage. Viable cell counts were increased to 5.65(CC) and 3.40(SVCC) LogCFU/g by 15 days(p<.0001) and increased more over time in foods prepared with CC than with SVCC. For the CC method, Coliform counts increased to 4.58 LogCFU/g by 15 days(p<.0001). With SVCC, colirorms were not detected at 0 days, but counts reached 3.70 LogCFU/g by 15 days(p<.0001). After reheating, no coliforms were detected for CC or SVCC at 0 days, however, by 15 days, coliform counts reached 3.61 and 2.52 LogCFU/g(p<.0001) for CC and SVCC, respectively. Finally, the sensory scores of SVCC were higher than those of CC.