• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.5
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• pp.2946-2952
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• 2014

The purpose of this study is to provide some basic information for elderly driving safety, by analyzing the current state. This study analyzed 128 survey questionnaires given to senior welfare center user in P city and evaluated Montreal Cognitive Assessment Korean Version(MoCA-K) and Neurobehavioral Cognitive Status Examination(NCSE) for checked 41 owner drivers by questionnaires. 32% of total elderly persons was owner driver, and 56.1% of elderly drivers was driving everyday. 56.1% of elderly persons was driving for 1-2hours per day. 46.3% of elderly persons was using a car for leisure activity and 31.7% of elderly drivers was experienced a car accident. As cognitive function evaluation, some elderly drivers showed scores lower than average in subcategories of cognitive functions for driving a car. So, methodical evaluation system for accurate evaluation of deficit ability and driving re-education system will be required for safety driving of elderly person. In future, a legal approach of government as driver licence management and renewal system will be required for safety driving of elderly person.

• Journal of the Korean Society of Food Science and Nutrition
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• v.30 no.5
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• pp.882-887
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• 2001

The purpose of this study was to investigated quality properties of breads prepared from wheat flour with persimon leaf power. Results showed that the volume of bread was lessened, the weight of bread went up, and baking loss rate diminished as persimmon leaf powder content incremented. The experiment showed that bread was maintained in the low level of springiness and cohesiveness was relatively reduced as time lapsed, whereas 3.0 and 5.0% test group remained significantly high level. There was a rapid increment in chewiness and gumminess, which tended to show significantly low as compared to control group, Results of sensory evaluation showed that the preference scores decreased as the persimmon leaf powder contents increased (p<0.05), flavor made no significant differences up to 3.0% test group, however, 5.0% test group containing elutionsuch as catechin or tannin produced sour and bitter taste so strongly that made if feel uncomfortable with. The augment of content indicated a low prederence in terms of texture, in an overall preference had no significant differences as compared to the control group, and 0.5% test group. Through the results of these of these experiments, we can conclude that the highest quality of persimmon leaf powder content is no more than 0.5% in making bread added with persimmon leaf powder.

• Korean Journal of Clinical Laboratory Science
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• v.53 no.4
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• pp.353-362
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• 2021

Cancer is a global health problem. There are diverse types of cancers, but there are several common pathways which lead to the development of cancer. Changes in gene expression might be the most common similarity found in almost all cancers. An understanding of the underlying changes in gene expression during cancer progression could lay a valuable foundation for the development of cancer therapeutics and even cancer vaccines. In this study, a well-known carcinogen, N-methyl-N'-nitro-N-nitrosoguanidine (MNNG), was employed to induce changes in gene expression in normal stomach cells. MNNG is known to cause cancer by inducing damage to DNA in MNNG-treated mammalian cells and animals fed with this carcinogen. An analysis was performed by comparing the differentially expressed genes (DEGs) caused by MNNG treatment with DEGs in stomach cancer cell lines. To this end, methods of analysis for functional categorization and protein-protein interaction networks, such as gene ontology (GO), the database for annotation, visualization, and integrated discovery (DAVID), Kyoto encyclopedia of genes and genomics (KEGG) and search tool for the retrieval of interacting genes/proteins (STRING), were used. As a result of these analyses, MNNG-regulated specific genes and interaction networks of their protein products that contributed to stomach cancer were identified.

• Journal of Microbiology and Biotechnology
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• v.31 no.3
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• pp.358-367
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• 2021

The World Health Organization (WHO) has declared the coronavirus disease 2019 (COVID-19) as an international health emergency. Current diagnostic tests are based on the reverse transcription-quantitative polymerase chain reaction (RT-qPCR) method, which is the gold standard test that involves the amplification of viral RNA. However, the RT-qPCR assay has limitations in terms of sensitivity and quantification. In this study, we tested both qPCR and droplet digital PCR (ddPCR) to detect low amounts of viral RNA. The cycle threshold (CT) of the viral RNA by RT-PCR significantly varied according to the sequences of the primer and probe sets with in vitro transcript (IVT) RNA or viral RNA as templates, whereas the copy number of the viral RNA by ddPCR was effectively quantified with IVT RNA, cultured viral RNA, and RNA from clinical samples. Furthermore, the clinical samples were assayed via both methods, and the sensitivity of the ddPCR was determined to be equal to or more than that of the RT-qPCR. However, the ddPCR assay is more suitable for determining the copy number of reference materials. These findings suggest that the qPCR assay with the ddPCR defined reference materials could be used as a highly sensitive and compatible diagnostic method for viral RNA detection.

• Journal of vocational education research
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• v.35 no.6
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• pp.65-84
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• 2016

This study aims to explore the duty system of the lifelong learning counseling, and to analyze the needs of counseling practice which are conceived by lifelong education practitioners. Based on the related prior studies, the duty system of lifelong learning counseling was investigated and classified. Also, differences of how to recognize the importance of counseling job and how to practice counseling are assessed by Borich method. After data were collected by practitioners from lifelong education field, the dependent t-test and the Borich needs assessment formula were used for analysis of the collected data. The results are as follows: the 4 subdivided duties of lifelong learning counseling are formation of relationship, learner's analysis, learning promotion, and follow-up management. The 11 tasks are learner's interview, providing learning information, analysis of learner's characteristics and needs, learning level diagnosis, diagnosis of learning inhibiting factors, promotion of learning motivation, advice of learning course and learning method, support of study circle activity, career planning counseling, follow-up counseling, and counseling evaluation. According to the needs assessment, learner's analysis is conceived as the most important duty among the 4 sub-duties, and learner's analysis is regarded as second important duty by the counseling practitioners. Among the 11 tasks, providing learning information is the most important tasks among counseling practitioners, and analysis of learner's characteristics and needs is followed as second task. The duty system of the lifelong learning counseling and needs assessment data can be used as the basic data for lifelong education practitioners to conduct the duty of lifelong learning counseling efficiently and to support the lifelong learning plan according to learner's characteristics.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.8
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• pp.313-320
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• 2019

This study compared and analyzed the levels of expectations of specialized hospitals, and the recognition of professional competency in specialized hospitals for the general public aged 20 years or older and those professionals on the hospital staffs who had more than three years of experience. The research period ran from July 2018 to May 2019. T-test and regression analysis were used for the analysis of the data. Research result; There was no difference in the level of expectations for the specialized hospitals between the general public and the hospital staffs. It was shown that the professional factor affecting subjective expectations of the specialized hospitals was a difference in the way of thinking between the general public and the hospital staff. The professional factor affecting the expected level of hospital use for the general public and hospital staffs was confidence in the doctors. However, the professional factors affecting the credibility of doctors differed between the general public and the hospital staff. The factor for the general public was excellent technical skill in the field, and the factor for the hospital staff was the specialized ability of doctor and their years of medical service. It is thought that efforts are needed to reduce the difference between the perception of hospital staff and that of the general public in order for specialized hospitals to continue to develop.

• Korean Journal of Clinical Laboratory Science
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• v.51 no.2
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• pp.185-190
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• 2019

Compression stockings are widely used for prevention of varicose vein. Depending on manufacture, there are diverse types of compression stockings available. Most common type of compression stocking might be the one cover calf of a lower leg which has 20~30 mmHg pressure. Despite being widely used, possible side effects that may occur by wearing compression stockings have not been studied much. We analyzed for a long wearing effect of compression stocking. Participants wore the compression stocking over one leg for 7 days. During the period, all the participants did their ordinary works wearing the compression stocking. Electrocardiogram (ECG), ankle-brachial index (ABI), blood pressure (BP), and electromyogram (EMG) were measured at 0 day, 3rd day and 7th day. There was no effect of wearing compression stockings from ECG, ABI or BP. Only EMG that was measured on the covered muscle increased proportionally to the wearing time. Interestingly, EMG from the opposite leg that had never been covered by compression stocking decreased in proportion to the wearing date. These results suggest wearing a compression stocking for varicose vein may cause unintentional increase or decrease of EMG from the wearing or non-wearing legs, respectively.

• Journal of The Korean Society of Integrative Medicine
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• v.8 no.4
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• pp.253-263
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• 2020

Purpose : The purpose of this study was conducted to compare the fear of falling, self-efficacy and fall prevention behavior according to the fall experience of the elderly. Methods : The subjects of this study were 162 elderly in B metropolitan city. The data collection period was from September 10th to November 30th of 2018. The collected data was processed using SPSS 21.0 and was analyzed using descriptive statistics, t-test, ANOVA, Scheffe's test. Results : The mean scores for fear of falling according to the fall experience and no fall experience of the elderly were 2.28±0.63 and 1.84±0.64 respectively and the results showed that fear of falling (t=4.26, p<.001) and self-efficacy of falling (t=3.88, p<.001) were significantly different between the two groups, but the mean scores for fall prevention behavior according to the fall experience and no fall experience of the elderly were 1.63±0.20 and 1.67±0.17 respectively and there was no significantly different in fall prevention behavior (t=-1.16, p=.25). Fear of falling according to the fall experience was significantly different by age (F=3.25, p<.05) and physical activity related to daily life (F=13.22, p<.001). Self-efficacy according to the fall experience was significantly different by age (F=3.03, p<.05), income per month (F=3.74, p<.05) and physical activity related to daily life (F=11.99, p<.001). But fall prevention behavior was no significantly different of general characteristics. Fear of falling according to the no fall experience was significantly different by age (F=3.37, p<.05), marriage status (F=3.37, p<.05), education level (F=5.15, p<.01), income per month (F=3.58, p<.05) and physical activity related to daily life (F=15.71, p<.001). Self-efficacy according to the no fall experience was significantly different by sex (t=2.32, p<.05), age (F=5.20, p<.01), marriage status (F=5.04, p<.01), education level (F=6.55, p<.001), income per month (F=5.99, p<.001) and physical activity related to daily life (F=18.86, p<.001). Fall prevention behavior was significantly different by marriage status (F=3.51, p<.05). Conclusion : The results of this study suggest the following : it is necessary to develop a program that can lower the fear of falling in the elderly and to increase the self-efficacy of falling, and to develop an education program that can improve the elderly's practice of fall prevention behavior regardless of the fall experience and to verify its effectiveness.

• International Journal of Oral Biology
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• v.46 no.2
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• pp.67-73
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• 2021

This study summarizes the recent cutting-edge approaches for dentin regeneration that still do not offer adequate solutions. Tertiary dentin is formed when odontoblasts are directly affected by various stimuli. Recent preclinical studies have reported that stimulation of the Wnt/β-catenin signaling pathway could facilitate the formation of reparative dentin and thereby aid in the structural and functional development of the tertiary dentin. A range of signaling pathways, including the Wnt/β-catenin pathway, is activated when dental tissues are damaged and the pulp is exposed. The application of small molecules for dentin regeneration has been suggested as a drug repositioning approach. This study reviews the role of Wnt signaling in tooth formation, particularly dentin formation and dentin regeneration. In addition, the application of the drug repositioning strategy to facilitate the development of new drugs for dentin regeneration has been discussed in this study.

• Korean Journal of Remote Sensing
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• v.38 no.5_3
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• pp.901-912
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• 2022

The frequency of disasters is increasing due to global climate change, and unusual heavy rains and rainy seasons are occurring in Korea. Periodic monitoring and rapid detection are important because these weather conditions can lead to drought and flooding, causing secondary damage. Although research using optical images is continuously being conducted to determine the waterbody, there is a limitation in that it is difficult to detect due to the influence of clouds in order to detect floods that accompany heavy rain. Therefore, there is a need for research using synthetic aperture radar (SAR) that can be observed regardless of day or night in all weather. In this study, using Sentinel-1 SAR images that can be collected in near-real time as open data, the UNet model among deep learning algorithms that have recently been used in various fields was applied. In previous studies, waterbody detection studies using SAR images and deep learning algorithms are being conducted, but only a small number of studies have been conducted in Korea. In this study, to determine the applicability of deep learning of SAR images, UNet and the existing algorithm thresholding method were compared, and five indices and Sentinel-2 normalized difference water index (NDWI) were evaluated. As a result of evaluating the accuracy with intersect of union (IoU), it was confirmed that UNet has high accuracy with 0.894 for UNet and 0.699 for threshold method. Through this study, the applicability of deep learning-based SAR images was confirmed, and if high-resolution SAR images and deep learning algorithms are applied, it is expected that periodic and accurate waterbody change detection will be possible in Korea.