• Journal of Oriental Neuropsychiatry
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• v.19 no.3
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• pp.85-100
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• 2008

Objective: This experiment was designed to investigate the effect of the KSKH hot water extract & ultra-fine powder on microglia and memory deficit model. Method: The effects of the KSKH hot water extract on expression of IL-1$\beta$, IL-6, TNF-$\alpha$ mRNA and production of IL-1$\beta$, IL-6, TNF-$\alpha$ in BV2 microglial cell line treated by lipopolysacchaide(LPS) were investigated. The effects of the KSKH hot water extract & ultra-fine-fine powder on the behavior of the memory deficit mice induced by scopolamine and AChE in serum of the memory deficit mice induced by scopolamine were investigated. Results: 1. The KSKH hot water extract suppressed the expression of IL-1$\beta$, IL-6, TNF-$\alpha$ mRNA in BV2 microglial cell line treated by LPS. 2. The KSKH hot water extract suppressed the production of IL-1$\beta$, IL-6, TNF-$\alpha$ in 100$\mu g/m\ell$ concentration of BV2 microglial cell line culture supernatant. 3. The KSKH hot water extract & ultra-fine powder decreased AChE activation significantly in the serum of the memory deficit mice induced by scopolamine. 4. The KSKH hot water extract & ultra-fine powder showed significant effect on memory impairment in the stop-through latency type of Morris water maze test. Conclusions: This experiment shows that the KSKH hot water extract & ultra-fine powder might be effective for the prevention and treatment of amnesia and Alzheimer's disease. Investigation into the clinical use of the KSKH hot water extract & ultra-fine powder for amnesia and Alzheimer's disease is suggested for future research.

• Journal of Oriental Neuropsychiatry
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• v.20 no.1
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• pp.43-57
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• 2009

Objectives : This experiment was designed to investigate the effect of the Hwanso-dan hot water extract & ultra-fine powder on microglia and memory deficit model Methods : The effects of the Hwanso-dan hot water extract on expression of IL-l${\beta}$, IL-6, TNF-${\alpha}$ mRNA and production of IL-l${\beta}$, IL-6, TNF-${\alpha}$ in BV2 microglial cell line treated by lipopolysacchaide were investigated. The effects of the Hwanso-dan hot water extract & ultra-fine powder on the behavior of the memory deficit mice induced by scopolamine and uric acid & AChE in serum of the memory deficit mice induced by scopolamine were investigated. Results : 1. The Hwanso-dan hot water extract suppressed the expression of IL-l${\beta}$, IL-6, TNF-${\alpha}$ mRNA in BV2 microglial cell line treated by lipopolysacchaide. 2. The Hwanso-dan hot water extract suppressed the production of IL-l${\beta}$, IL-6, TNF-${\alpha}$ in BV2 microglial cell line. 3. The Hwanso-dan hot water extract & ultra-fine powder decreased uric acid and AChE significantly in the serum of the memory deficit mice induced by scopolamine. 4. The Hwanso-dan hot water extract & ultra-fine powder groups showed significantly inhibitory effect on the scopolamine${\sim}$induced impairment of memory in the experiment of Morris water maze. Conclusions : This experiment shows that the Hwanso-dan hot water extract & ultra-fine powder might be effective for the prevention and treatment of Memory deficit disease. Investigation into the clinical use of the Hwanso-dan hot water extract & ultra-fine powder for Alzheimer's disease is suggested for future research.

• Proceedings of the KIEE Conference
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• 2004.11b
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• pp.46-50
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• 2004

This paper analysed the induced current density inside human body of hot-line worker for 765kV double circuit transmission line according to locations of human body Human was modelled by several organs, which included brain, heart, lungs, liver and intestines. We applied the 3 dimensional boundary element method to calculate induced electric fields.

• Proceedings of the KIEE Conference
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• 2006.05a
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• pp.5-7
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• 2006

In this paper, developed a uninterruptible hotline tools and method for replacement of strain pole crossarm on overhead distribution line. For practical use of developed tools, following direct hot-line methods were proposed: 'Direct hot-lire method for replacement of pin pole crossarm', 'Direct hot-line method for alteration of crossarm' and 'Crossarm replacement method in uninterruptible cable displacement area'. These methods were proposed more simple and safe working on hotline job.

• Proceedings of the Korean Society of Machine Tool Engineers Conference
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• 2003.04a
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• pp.124-129
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• 2003

In the face of global competitor the requirements flor the continuously increasing productivity, flexibility and quality(dimensional accuracy, mechanical properties and surface properties) have imposed a major change on steel manufacturing industries. Indeed, one of the keys to achieve this goal is the automation of the steel-making process using AI(Artificial Intelligence) techniques. The automation of hot rolling process requires the developments of several mathematical models fir simulation and quantitative description of the industrial operations involved. In this paper, a on-line training neural network for both long-term teaming and short-term teaming was developed in order to improve the prediction of rolling force in hot rolling mill. This analysis shows that the predicted rolling force is very closed to the actual rolling force, and the thickness error of the strip is considerably reduced.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 1999.08a
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• pp.111-118
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• 1999

This article describes the basic engineering concepts to be considered in the application of an induction heating furnace in the hot-dip galvanizing line. Experience in the Dongkuk project in Pohang, has shown that this arrangement has many advantages over the conventional method of using a combustion-gas heated furnace. Investment and operating costs are lower, the line length is much shorter, line operation is more convenient, air pollution is reduced, and the coated strip at of top-quality. As these benefits become well known, it is anticipated that the concept of induction heating will be more widely used in both new and revamped process lines. Induction heating is suitable for the production of Commercial Quality hot galvanized coils. More research is required to extend the present concept to the production of higher forming grades such as Drawing, Deep Drawing and Extra Deep Drawing Quality steels. A combination of induction heating and combustion-gas heating may lead to the way to the processing of these qualities of strip.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2005.05a
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• pp.428-431
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• 2005

This paper describes the process design for hot forging of bearing hub. Forging processes of bearing hub are simulated using the rigid-plastic finite element method. In the process called closed die forging without flash, the design of blocker geometry is of critical importance. Forging processes designs are take advantage of computer aided Process planning and experts. But that is difficult to predict metal flow line. So the preform is designed by the expert, and modified through predict metal flow line by CAE. This paper is to approach preform design considered defect such as metal flow and unfitting etc. at the finisher process.

• 제어로봇시스템학회:학술대회논문집
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• 2000.10a
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• pp.167-167
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• 2000

This study aims at the development of REC sensor causing the gauge error in the hot strip rolling process, and the improvement of the hydraulic AGC (Automatic Gauge Control) system. The gauge error outbreaks from the various reasons, however, mainly the roll eccentricity is considered to cause a such kind of error. In the study, the REC (Roll Eccentricity Control System) sensor is designed using sensor An On - line test of the system shows the comprehensive effects of controlling the gauge error of the hot strip. On - Line test shows the possibility of enhancing the accuracy for gauge.

• Transactions of Materials Processing
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• v.11 no.1
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• pp.24-35
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• 2002

Recent trend and future prospect of flat rolling of steel has been summarized based on the earlier reports. Key technology in the plate rolling is to have ultra fine microstructure having high resistance against crack propagation during application. Heavy accelerated cooling facility and high power rolling mill will be helpful to develope the high toughness steel. Precise modeling of properly prediction based on deformation and transformation imposed on microstructure of steel during processing is highly anticipated. For the hot strip rolling process, new trend is lies on the production of ultra-thin gauged hot strip to substitute cold rolled strip. For the substitution of cold rolled strip into hot rolled strip widely, high formable property of hot strip is highly required. For the formabilit, the ferritic rolling of extra low carbon steel under high lubricated condition is essential. Recently introduced semi-continuous thin slab and rolling mill line is very plausible to develope those kinds of products easily In the view groin facility combination. New idea to modify the existing continuous hot strip mill line to produce the ultra thin-gauged hot strip in an economic way is suggested in this report.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2005.07a
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• pp.655-656
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• 2005

In the future, plastic based system will play a crucial role in modem life, for examples, transparent display or disposable electronics and so on. In this paper, we introduced a new method to fabricate the metal line on the plastic substrate. Metal lines were fabricated by hot embossing and CMP process on PMMA (polymethylmethacrylate) substrates. A Si mold was made by wet etching process and a PMMA wafer was cut off from I mm thick PMMA sheet. A 100 nm thick Al was deposited on PMMA wafers. The Al deposited PMMA wafer and the Si mold carefully sandwiched which was directly imprinted by hot embossing. After imprinting process, a residual Al layer was removed by CMP process. Finally, we found the entire process may be very useful to fabricate the metal line on plastic substrates.