• Title/Summary/Keyword: (1$\rightarrow$3)-$\beta$-D-glucan synthase

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Isolation and Characterization of Saccharomyces cevevisiae Mutants Deficient in (1$\rightarrow$3)-$\beta$-D-Glucan Synthase (베타-1,3-글루칸 생합성능이 손상된 Saccharomyces cerevisiae 돌연변이체의 선별 및 특성)

  • 송미령;이동원;배경숙;박희문;박상원
    • Microbiology and Biotechnology Letters
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    • v.20 no.6
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    • pp.642-646
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    • 1992

  • We have isolated conditional lethal mutants of Saccharomyces cerevisiae which are low in (1 ~3)-~-D-glucan synthase activity. These mutants were osmotic sensitive at nonpermissive temperature (37$^{\circ}$C) and showed a decreased level of alkali-insoluble cell wall glucan. The decrease in (1 ~3)-~-D-glucan synthase activity of the mutants appeared to be mainly due to the defect in catalytic component rather than in GTP-binding component.

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