• Title/Summary/Keyword: ($(Gd\

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Effect of Gd-DTPA on Diffusion in Canine Brain with Hyperacute Stroke (초급성 뇌경색을 일으킨 개에서 Gd-조영제의 주입이 뇌의 확산에 미치는 영향)

  • 김범수;정소령;신경섭
    • Investigative Magnetic Resonance Imaging
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    • v.6 no.2
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    • pp.158-165
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    • 2002
  • Purpose : To evaluate the effect of Gd-DTPA on signal intensity of diffusion-weighted magnetic resonance(MR) image and apparent diffuse coefficient (ADC) in dog brain with hype racute stroke. Materials and methods : Experimental canine model of hyperacute cerebral infarction was made by selective intraarterial embolization with particulate embolic material. Diffusion-weighted MR imaging was performed in five dogs at 1 hour after the embolization of internal carotid artery. After intravenous bolus injection of Gd- DTPA, additional 11 diffusion-weighted MR images were serially obtained from 2 minutes to 90 minutes after injection in each dog. The author evaluated findings of hyperacute cerebral infarction on diffusion-weighted MR imaging, and calculated mean signal intensity and mean ADC in infarcted region and contralateral normal region. Statistical analysis of mean signal intensity, mean ADC and contrast-noise ratio before and after Gd-DTPA injection was performed. Results : Hyperacute cerebral infarction developed in all five dogs on diffusion-weighted MR images obtained 1 hour after embolization. The area of hyperacute infarction had steady increase in signal intensity on diffusion-weighted MR image and decrease in ADC. In normal perfusion area, decrease in signal intensity was observed at 2 minutes the Gd-DTPA injection, whereas ADC did not changed. Conclusion : Intravenous injection of Gd-DTPA had no influence on ADC in both hyperacute infarction and normally perfused are a, but caused initial transient signal reduction in normally perfused area on diffusion-weighted MR image due to susceptibility effect of Gd-DTPA. It is important to calculate ADC in evaluating the effect of diffusion after injection of Gd-DTPA.

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Mossbauer Studies of Perovskite $Gd_{1-x}Sr_xFeO_{3-y}$ (X = 0.0, 0.5) (Perovskite $Gd_{1-x}Sr_xFeO_{3-y}$ (X = 0.0, 0.5)의 Mossbauer연구)

  • 엄영랑;김철성;서정철;오영제
    • Journal of the Korean Magnetics Society
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    • v.8 no.2
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    • pp.67-73
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    • 1998
  • Crystallographic and magnetic properties of perovskite $Gd_{1-x}Sr_xFeO_{3-y}$ (x=0.0, 0.5) substituted $Sr^{2+}$ having larger inoic radius than $Gd^{3+}$ at GdFeO$_3$have been studied by x-ary diffraction, M$\ "{o}$ssbauer spectroscopy, and VSM. The cystal structures are found to be orthorhombic with the lattice parameters : $a_o=5.53\;{\AA},\;b_o=5.608\;{AA},\;C_o=7.724\;{\AA}$ for $Gd_{0.5}Sr_{0.5}FeO_{3-y}$ (x=0.0, 0.5) have been investigated over temperature range from 4.2 to 690 K using the M$\ "{o}$ssbauer technique. The Neel temperatuer of $Gd_{1-x}Sr_xFeO_{3-y}$ system is 690 K with x value of 0.0 and 515 K with x value of 0.5. Analysis of M$\ "{o}$ssbauer spectra Mohr's salt analysis for $Gd_{1-x}Sr_xFeO_{3-y}$ demonstrated the existence of the mixed valence states of iron and the coordination state of $Fe^{3+}$ and $Fe^{4+}$ ions. The Corresponding hyperfine parameters for GdFeO$_3$ are compatible with S=5/2 $Fe^{3+}$ in octahedral cooedination.l cooedination.

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Development of High Strength Mg-Zn-Gd Alloys by Rapid Solidification Processing

  • Kim, Min-Chul;Yamasaki, Michiaki;Kawamura, Yoshihito
    • Proceedings of the Korean Powder Metallurgy Institute Conference
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    • 2006.09b
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    • pp.1048-1049
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    • 2006
  • Rapidly solidified ribbon-consolidation processing was applied for preparation of high strength bulk Mg-Zn-Gd alloys. Mg alloys have been used in automotive and aerospace industries. Rapid solidification (RS) process is suitable for the development of high strength Mg alloys, because the process realizes grain-refinement, increase in homogeneity, and so on. Recently, several nanocrystalline Mg-Zn-Y alloys with high specific tensile strength and large elongation have been developed by rapidly solidified powder metallurgy (RS P/M) process. Mg-Zn-Y RS P/M alloys are characterized by long period ordered (LPO) structure and sub-micron fine grains. The both additions of rare earth elements and zinc remarkably improved the mechanical properties of RS Mg alloys. Mg-Zn-Gd alloy also forms LPO structure in -Mg matrix coherently, therefore, it is expected that the RS Mg-Zn-Gd alloys have excellent mechanical properties. In this study, we have developed high strength RS Mg-Zn-Gd alloys with LPO structure and nanometer-scale precipitates by RS ribbon-consolidation processing. $Mg_{97}Zn_1Gd_2$ and $Mg_{95.5}Zn_{1.5}Gd_3$ and $Mg_{94}Zn_2Gd_4$ bulk alloys exhibited high tensile yield strength (470 MPa and 525 MPa and 566 MPa) and large elongation (5.5% and 2.8% and 2.4%).

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Effects of Salt, Glucono-$\delta$-Lactone and High Pressure Treatment on Physico-Chemical Properties of Restructured Pork (소금과 Glucono-$\delta$-Lactone의 첨가 및 초고압 처리가 재구성 돈육의 이화학적 특성에 미치는 영향)

  • Hong, Geun-Pyo;Park, Seong-Hui;Kim, Ji-Yeon;Go, Se-Hui;Min, Sang-Gi
    • the MEAT Journal
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    • s.34 winter
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    • pp.26-39
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    • 2007
  • This study investigated the effect of salt and glucono-$\delta$-lactone (GdL) on the cold-set binding of restructured pork washed and pressurized at 200 MPa. Binding strength, pH, water holding capacity (WHC) and color were determined. NaCl improved pH, WHC and binding strength. GdL also increased binding strength while decreased WHC and pH significantly (p<0.05). However, low GdL level combined with NaCl showed high pH and WHC, compared to control. In color, NaCl decreased L*-value with increasing a*-value significantly (p<0.05). In contrast to NaCl, GdL increased L*-value and decreased a*-value. GdL tended to decrease b*-value and significant differences were found when GdL was added above 1%. Pearson’s correlation coefficients presented that NaCl had a significant effect on binding strength (0.6632) and lightness (?0.7330) while GdL had a significant correlation with all parameters barring binding strength. The results indicated that under washing and pressure treatments, GdL had a potential effect on cold-set binding with reducing NaCl concentration, especially when low GdL concentration combined with NaCl was added.

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Acute Adverse Reactions to Gadolinium-based Intravenous Contrast Agents for MRI : Retrospective Analysis Using Computed Reporting System (자기공명영상검사용 가돌리늄 경정맥 조영제의 급성 부작용: 부작용 전산 체계를 이용한 후향적 분석)

  • Choi, Moon-Hyung;Choi, Joon-Il;Jung, Seung-Eun;Ahn, Kook-Jin;Lee, Hae-Giu
    • Investigative Magnetic Resonance Imaging
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    • v.15 no.2
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    • pp.139-145
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    • 2011
  • Purpose : To assess the frequency and severity of acute adverse reactions to intravenous administration of gadolinium-based contrast agents using computerized reporting system at a single large academic institution. Materials and Methods : We assessed data from electronic hospital information system from October 2008 to December 2010. Reactions were classified as mild, moderate, or severe. We compared the frequency of adverse reactions among three contrast agents (Gd-BT-DO3A, Gd-DTPA and Gd-EOB-DTPA). Results : The total number of administrated contrast agents was 33,600, and the number of administration of Gd-BT-DO3A, Gd-DTPA and Gd-EOB-DTPA were 20,824 (62%), 10,417 (31%) and 2,359 (7%), respectively. Total 39 adverse reactions were reported accounting for 0.1161% of all administrations. The incidences of adverse reactions were 0.1248% (26/39, 67%) for Gd-BT-DO3A, 0.0768% (8/39, 21%) for Gd-DTPA, and 0.2120% (5/39, 13%) for Gd-EOB-DTPA. The difference of frequencies of adverse reaction among three contrast agents was not significant. Most cases of the adverse effect were mild (35/39, 89.7%). Moderate and severe adverse reactions were encountered in two patients, respectively. Conclusion : Among Koreans, adverse effects were rare, and especially, moderate to severe adverse reactions were much rarer. There was no difference among the frequencies of adverse reactions caused by three different contrast agents.

Effects of Salt, Glucono-${\delta}$-Lactone and High Pressure Treatment on Physico-Chemical Properties of Restructured Pork (소금과 Glucono-${\delta}$-Lactone의 첨가 및 초고압 처리가 재구성 돈육의 이화학적 특성에 미치는 효과)

  • Bong Geun-Pyo;Park Sung-Hee;Kim Jee-Yeon;Ko Se-Hee;Min Sang-Gi
    • Food Science of Animal Resources
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    • v.26 no.2
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    • pp.204-211
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    • 2006
  • This study investigated the effect of salt and glucono-${\delta}$-lactone (GdL) on the cold-set binding of restructured pork washed and pressurized at 200 MPa. Binding strength, PH, water holding capacity (WHC) and color were determined. NaCl improved pH, WHC and binding strength. GdL also increased binding strength while decreased WHC and pH significantly (p<0.05). However, low GdL level combined with NaCl showed high pH and WHC, compared to control. In color, NaCl decreased $L^*$-value with increasing $a^*$-value significantly (p<0.05). In contrast to NaCl, GdL increased $L^*$-value and decreased $a^*$-value. GdL tended to decrease $b^*$-value and significant differences were found when GdL was added above 1%. Pearson's correlation coefficients presented that NaCl had a significant effect on binding strength (0.6632) and lightness (-0.7330) while GdL had a significant correlation with all parameters barring binding strength. The results indicated that under washing and pressure treatments, GdL had a potential effect on cold-set binding with reducing NaCl concentration, especially when low GdL concentration combined with NaCl was added.

Superconducting Properties of Large Single Grain Gd1.5Ba2Cu3O7-y Bulk Superconductors (대면적 단결정 Gd1.5Ba2Cu3O7-y 벌크 초전도체의 초전도 특성)

  • Kim, Chan-Joong;Park, Seung Yeon;Kim, Kwang-Mo;Park, Soon-Dong;Jun, Byung-Hyuk
    • Korean Journal of Materials Research
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    • v.22 no.11
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    • pp.569-574
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    • 2012
  • Large single grain $Gd_{1.5}Ba_2Cu_3O_{7-y}$ (Gd1.5) bulk superconductors were fabricated by a top-seeded melt growth (TSMG) process using an $NdBa_2Cu_3O_{7-y}$ seed. The seeded Gd1.5 powder compacts with a diameter of 50 mm were subjected to the heating cycles of a TSMG process. After the TSMG process, the diameter of the single grain Gd1.5 compact was reduced to 43 mm owing to the volume contraction during the heat treatment. The superconducting transition temperature ($T_c$) of the top surface of the single grain Gd1.5 sample was as high as 93.5 K. The critical current densities ($J_cs$) at 77 K and 1T and 1.5 T were in ranges of 25,200-43,900 $A/cm^2$ and 10,000-23,000 $A/cm^2$, respectively. The maximum attractive force at 77 K of the sample field-cooled using an Nd-B-Fe permanent magnet (surface magnetic field of 0. 527 T) was 108.3 N; the maximum repulsive force of the zero field-cooled sample was 262 N. The magnetic flux density of the sample field-cooled at 77 K was 0.311T, which is approximately 85% of the applied magnetic field of 0.375 T. Microstructure investigation showed that many $Gd_2BaCuO_5$ (Gd211) particles of a few ${\mu}m$ in size, which are flux pinning sites of Gd123, were trapped within the $GdBa_2Cu_3O_{7-y}$ (Gd123) grain; unreacted $Ba_3Cu_5O_8$ liquid and Gd211 particles were present near the edge regions of the single grain Gd1.5 bulk compact.

Effect of Gd-EOB-DTPA on Hepatic Fat Quantification using Two-point Dixon Technique (Two-point Dixon기법을 이용한 간의 지방정량화에 Gd-EOB-DTPA가 미치는 영향)

  • Koo, No-Hyun;Choi, Kwan-Woo;Yoo, Beong-Gyu
    • The Journal of the Korea Contents Association
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    • v.17 no.7
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    • pp.215-221
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    • 2017
  • The purpose of present study was to assess whether Gd-EOB-DTPA with gadolinium-based contrast agent administration affects fat quantification using the two-point Dixon technique. Between April 2016 and September, 60 patients who underwent hepatic fat quantification using the two-point Dixon technique were divided into two group (normal liver donors=30, abnormal hepatic steatosis=30) and we compared the variability of mean fat fraction before and after administration Gd-EOB-DTPA. As a results, in both group, fat fraction after injection Gd-EOB-DTPA was significantly decreased (normal liver donors -33.8%, hepatic steatosis -47.2%) compared to before injection Gd-EOB-DTPA, suggesting that Gd-EOB-DTPA affects fat quatification using two-point Dixon technique. In conclusion, hepatic fat quantification using the two-point Dixon technique could maintain diagnostic value by acquiring images before administration Gd-EOB-DTPA.

Effect of GdL Addition on Physico-chemical Properties of Fermented Sausages during Ripening

  • Yim, Dong-Gyun;Jang, Kyoung-Hwan;Chung, Ku-Young
    • Food Science of Animal Resources
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    • v.35 no.3
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    • pp.322-329
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    • 2015
  • This study investigated the effects of glucono-δ-lactone (GdL) addition on physicochemical and microbiological characteristics of fermented sausages during ripening and drying. Five batches of sausages were produced under ripening conditions: without GdL and with 0, 0.1, 0.25, 0.5 and 0.75% of GdL addition. Samples from each treatment were taken for physicochemical and microbiological analyses on the 0, 1, 3, 5, 7, 10, 15, 20 and 25th day of ripening. Chemical analysis showed a significant decrease in moisture content of sausages with increasing amounts of GdL added (p<0.05). The moisture contents decreased, whereas the fat, protein and ash contents increased throughout ripening (p<0.05). Increasing levels of GdL caused a decrease in the pH values (p<0.05), which can have an inhibitory effect against microflora. Water holding capacity content of samples decreased with increasing GdL concentration (p<0.05). The shear force values of fermented sausages showed the highest in T4 (p<0.05). During ripening, the shear force values of sausages were increased on the 25th day compared to day 0 (p<0.05). The higher GdL level produced lighter and more yellow sausages. The addition of 0.75% GdL was effective in controlling bacteria counts. Addition of GdL in sausages resulted in the physicochemical and microbiological attributes equal to or better than no addition of GdL without any harmful effect.

Dispersion and Shape Control on Nanoparticles of Gd2O3:Eu3+ Red Phosphor Prepared by Template Method (주형법으로 제조된 Gd2O3:Eu3+ 적색 형광체의 나노입자 분산 및 형상제어)

  • Park, Jeong Min;Ban, Se Min;Jung, Kyeong-Youl;Choi, Byung-Ki;Kang, Kwang-Jung;Kim, Dae-Sung
    • Korean Journal of Materials Research
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    • v.27 no.10
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    • pp.534-543
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    • 2017
  • $Gd_2O_3:Eu^{3+}$ red phosphors were prepared by template method from crystalline cellulose impregnated by metal salt. The crystallite size and photoluminescence(PL) property of $Gd_2O_3:Eu^{3+}$ red phosphors were controlled by varying the calcination temperature and $Eu^{3+}$ mol ratio. The nano dispersion of $Gd_2O_3:Eu^{3+}$ was also conducted with a bead mill wet process. Dependent on the time of bead milling, $Gd_2O_3:Eu^{3+}$ nanosol of around 100 nm (median particle size : $D_{50}$) was produced. As the bead milling process proceeded, the luminescent efficiency decreased due to the low crystallinity of the $Gd_2O_3:Eu^{3+}$ nanoparticles. In spite of the low PL property of $Gd_2O_3:Eu^{3+}$ nanosol, it was observed that the photoluminescent property was recovered after re-calcination. In addition, in the dispersed nanosol treated at $85^{\circ}C$, a self assembly phenomenon between particles appeared, and the particles changed from spherical to rod-shaped. These results indicate that particle growth occurs due to mutual assembly of $Gd(OH)_3$ particles, which is the hydration of $Gd_2O_3$ particles, in aqueous solvent at $85^{\circ}C$.