• Korean Journal of Food Science and Technology
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• v.51 no.3
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• pp.263-271
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• 2019

In this study, we examined the immunostimulating characteristics of a hot water extract (RCW) and crude polysaccharides (RCP) of red cabbage. RCW and RCP did not show any cytotoxicity in B16BL6 cells and macrophages. Although the sugar compositions of RCW and RCP were similar, the uronic acid content of RCP was higher than that of RCW RCP significantly increased the production of various cytokines and NO, whereas RCW did not affect the production of cytokines and NO. In an ex vivo assay of natural killer (NK) cell activity, intravenous (i.v.) administration of RCP significantly augmented NK cytotoxicity against Yac-1 tumor cells at 3 days after RCP treatment. In an experimental lung metastasis model using B16BL6 melanoma cells, i.v. administration of RCP at a dose of $1,000{\mu}g$ per mouse significantly inhibited 47.3% of lung metastasis. These results suggest that crude polysaccharide isolated from red cabbage is a promising food ingredient for the prevention of tumor metastasis.

• Korean Journal of Plant Resources
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• v.32 no.5
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• pp.457-462
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• 2019

This study was conducted to investigate seed dormancy type and germination characteristics of Lonicera chrysantha. In imbibition test, the seeds imbibed water readily. Therefore, the seeds did not have physical dormancy (PY). The seeds have undeveloped embryo at seed dispersal and, then the E:S ratio (embryo/seed ratio) increased more than about 46% just before germination. In temperature experiments (5, 15, 20 and $25^{\circ}C$), the seeds did not germinate during incubation at $5^{\circ}C$. At $20^{\circ}C$, the seeds started to germinate from a week after sowing and the final germination was 86.7% at 2 weeks after sowing. At $15^{\circ}C$, the seeds started to germinate at 2 weeks and the final germination rate was 75.0% at 4 weeks after sowing. At $25^{\circ}C$, the seeds started to germinate at a week and the final germination rate was 48.3% at 19 weeks after sowing. Consequently, Optimum temperature of germination is $20^{\circ}C$ that shown highest final germination rate and shortest mean germination time. The seeds germinated all temperature treatments within 4 weeks except to $5^{\circ}C$. Therefore, it is concluded that seeds of L. chrysantha have only morphological dormancy (MD).

• Korean Journal of Plant Resources
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• v.32 no.5
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• pp.471-477
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• 2019

Rehmannia glutinosa is a perennial herb belonging to family Scrophulariaceae. This study was conducted to evaluate the appropriateness cultivation of R. glutinosa in Southern Gangwon Province. The seed rhizomes of R. glutinosa 'Jihwang 1' were planted in the early May and harvested in the early November. Agronomic characteristics and catalpol content was evaluated in comparison with Eumseong area. As a results, aerial parts of Pyeongchang area in leaf length and leaf width were better than other cultivation area but the leaf number per plant was statistically the same. And underground parts of Eumseong area in rhizome yield and number of rhizome were better than other cultivation area. Conversely, rhizome diameter of Pyeongchang and Jeongseon area were thicker than rhizome diameter of Eumseong area. The fresh rhizome yield of Eumseong, Jeongseon and Pyeongchang area were 1,848, 1,571, and 1485 kg/10a, respectively, higher than the domestic average production of 805 kg/10a. And, catalpol content of Pyeongchang, Jeongseon and Eumseong area were 1.93, 1.62 and 1.99%, respectively. Taken together, R. glutinosa cultivation in the region of southern Gangwon province is considered to be possible, but further evaluation of the economic aspect is needed.

• Journal of Forest and Environmental Science
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• v.37 no.1
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• pp.52-61
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• 2021

Decay fungi can decompose plant debris to recycle carbon in the ecosystem. Still, they can also be fungal pathogens, which can damage living trees and/or wood material and cause a large amount of timber loss. We isolated and identified basidiomycetous fungi from the decayed bark of Mongolian oak wrapped with sticky roll traps. The degrading enzyme activities were then tested for all fungal isolates. The decay ability of selected isolates was assessed based on the weight loss of wood discs after inoculating with culture suspension of decay fungi under the different humidity levels. A total of 46 basidiomycetous fungal isolates belonged to 12 species, and 10 genera were obtained from Jong Myo (16 isolates), Chang Kyung palace (7 isolates), Cheong Gye (10 isolates), and Gun Po (13 isolates). Gymnopus luxurians was the most dominant fungus in the present study, and this species distributed in all survey sites with 9 isolates in Jong Myo, followed by 3 isolates in Chang Kyung palace, while Cheong Gye and Gun Po had only 1 isolate each. Among 46 isolates, 44 isolates secreted at least one enzyme, while 25 isolates produced both cellulase and phenol oxidase enzymes, and 2 isolates produced neither. The assessment of decay ability by artificial inoculation indicated that the weight loss of wood discs was significantly influenced by humidity conditions when inoculated with bark decay fungi. The percent weight losses by G. luxurians inoculation in RH of 90-100% and RH of 65-75% were 4.61% and 2.45%, respectively. The weight loss caused by Abortiporus biennis were 6.67% and 0.46% in RH of 90-100% and RH of 45-55%, respectively. The humidity reduction approach should be applied for further studies to control the growth and spread of bark decay fungi on the trunks wrapped with sticky roll traps.

• Korean Journal of Optics and Photonics
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• v.33 no.6
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• pp.331-337
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• 2022

Raman spectroscopy is an optical technique that can identify molecules in a label-free manner, and is therefore heavily investigated in various areas ranging from biomedical engineering to materials science. Probe-based Raman spectroscopy can perform minimally invasive chemical analysis, and thus has potential as a real-time diagnostic tool during surgery. In this study, Raman experimentation was calibrated by examining the Raman shifts with respect to the concentrations of chemical substances. Raman signal characteristics, targeted for normal mice and cerebral tissues of the 5xFAD dementia mutant model with accumulated amyloid beta plaques, were measured and analyzed to explore the possibility of diagnosis of Alzheimer's disease. The application to the diagnosis of dementia was cross-validated by measuring Raman signals of amyloid beta. The results suggest the potential of Raman spectroscopy as a diagnostic tool that may be useful in various areas of application.

• Korean Journal of Legislative Studies
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• v.24 no.2
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• pp.39-66
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• 2018

This paper analyzes the structures and issues of 2018 Korean local elections based on the author's observations on the electoral processes. Even if this paper does not follow a traditional statistical method, it provides the interpretative meanings of 2018 local elections by utilizing an expert's observations of campaign processes. This result of 2018 election can be summarized into two analytical frames. In terms of electoral competition structure, three key factors, such as presidential approval rating, party competition structure, ideological spectrum, tend to affect the winning of governing party. In the light of election issue, the inter-Korean summit, the Washington-Pyeongyang summit, Incheon deprecating remark were positive to the vote gains of governing party, but the negative campaign, the drucking scandal and the swing voters were found not to be significant. The local election in Korea tends to show dual meanings, a proxy war of national-level politics and a composition process of local government. This paper found that the 2018 election has dual meanings at the same time, in a sense that it is the punishment of the ex-governing party's wrongdoing and the power change of local government.

• (The)Study of the Eastern Classic
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• no.69
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• pp.531-561
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• 2017

This article's aim is to contrast Dasan's commentary with Chu-tzu' and old commentary on The Meaning of learning(學) and ming(命) in Confucius Analects analects. Confucius Analects analects began with Confucius said, " Is it not pleasant to learn with a constant perseverance and application?"(1:1), and closed with Confucius said, "Without recognizing the ordinances of Heaven, it is impossible to be a superior man. We can consider Confucian analects as theory of science. I've tried to define the meaning of learning(學) in Confucius Analects, at first. The Meaning of learning in Confucian analects have 1) Technology, 2) the way of human relation, 3) liberal ar, and 4) 'learning to become a sage. Chu-tzu defines learning(學) in Confucius Analects as 'learning to become a sage'. Dasan's considered learning(學) as science in general. Chu-tzu' and old commentary defined zhiming(知命) in Confucius Analects is 'to know the fact that there is destiny in man's life(ex, life and death). Dasan reinterpreted ming(命) in Confucius Analects as human mind-nature.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.12
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• pp.440-448
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• 2020

This study was conducted to identify the factors affecting breastfeeding in adult women based on socio-demographic and health-related characteristics using the results of KNHANES VII-3. The data was analyzed by applying weights, using the complex sample analysis method of the SPSS Win 22.0 program. Breastfeeding was influenced significantly by age, education level, and the current smoking status. Women in the age group of 30-39 years had a breastfeeding rate that was 3.06 times higher than 19-29 year old women. Also, the breastfeeding rates for women with an education level under elementary school were 4.70 times higher than those with a college degree or higher education level and non-smokers and ex-smokers had levels 2.51 times higher than smokers. Therefore, for mothers under the age of 30, education on breastfeeding should be further strengthened. For mothers over 40 years old, lactation support to increase the milk supply should be provided as well as assistance toward care for other children in the family. Also, better-educated mothers will need to learn effective breastfeeding methods in limited environments such as work-life, and a social atmosphere needs to be established that is considerate to lactating women. Furthermore, education related to pregnancy and lactation should be provided for use in smoking cessation programs for female smokers.

• The Korea Journal of Herbology
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• v.36 no.2
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• pp.1-9
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• 2021

Objectives : Gossypium arboreum (cotton) is traditionally used to treat various health disorders. However, anti-amnesic effect of G. arboreum has not been reported. The objective of this study was to investigate in-vivo the anti-amnesic effects along with in vitro antioxidant and acetylcholinesterase (AChE) inhibition potential in G. arboreum seed essential oil. Methods : The essential oil of G. arboreum obtained by solid phase microextraction (SPME) techniques were identified by gas chromatography-mass spectroscopy (GC-MS). 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assay were performed to determine the antioxidant activity at various concentrations (312.5, 625, 1250, 2500, 5000, 10000 ㎍/㎖. Y-maze, passive avoidance and Morris water maze tests were carried out to evaluate improved effect on scopolamine (1 mg/kg)-induced memory dysfunction at the dose level of 50, 100 and 200 mg/kg. Donepezil (5 mg/kg) was used as a positive drug control. We performed acetylcholinesterase (AChE) activity assay in ex vivo. Results : Five volatile compounds were identified in G. arboreum. The assays of DPPH and ABTS revealed that G. arboreum increased antioxidant activity in a dose-dependent manner. G. arboreum ameliorated the percent of spontaneous alternation in the Y-maze test, shortened step-through latency in the passive avoidance test, and increased swimming time in the target zone in the Morris water maze test. In addition, G. arboreum inhibited the AChE activity. Conclusions : Based on these findings, G. arboreum may aid in the prevention and treatment of learning and memory-deficit disorders through antioxidant and AChE inhibitory activities.

• Journal of Applied Biological Chemistry
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• v.64 no.1
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• pp.75-81
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• 2021

Recent gut microbiota studies have revealed the important roles of gut microbiota for our health. Increasing numbers of health functional foods have been developed every year. Development of functional food often includes ex- and in-vivo experiment to verify the beneficial effects of the functional food. To investigate effects of functional food on gut microbiota, animal models were often conducted. Beneficial effects of food can be evaluated based on how gut microbiota was shifted by food, which results in either increase in beneficial bacteria, decrease in potentially pathogenic bacteria or both. As animal experiments are generally time-consuming and laborious, we investigate how well in-vitro investigation of fecal microbiota may reflect dietary health benefits. Here, we tested 15 kinds of diets using two human subjects' fecal materials. Our results showed varying gut microbiota shifts according to diets, which suggested generally known beneficial diets (i.e. Kimchi, Chunggukjang) increased Lactobacillus and Bifidobacterium. Therefore, we suggest that in vitro fecal microbiota analysis could be used to evaluate beneficial effects of diets. Moreover, this method may be ideal to establish personalized diet.