• 한국환경복원기술학회지
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• 제12권6호
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• pp.1-17
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• 2009

This study was carried out to classify vegetation structure of the Anseong district in the Deogyusan National Park from May 2007 to September 2008 using the gradient analyses and phytosociological method. The vegetation communities were classified into Quercus mongolica, Carpinus laxiflara, Q. serrata, Fraxinus mandshurica, Betula davurica, B. costata, Pinus densiflora and Abies koreana. Characteristics of the vegetation such as species composition, layer structure, vegetation ratio, and the distribution of individual trees by DBH were significantly different among communities. The order of important value of the forest community with DBH 2cm above plants was Q. mongolica (40.02), C. laxiflora (25.65), Q. serrata (24.68), F. mandshurica (21.66), P. densiflora (19.12), Acer pseudosieboldianum (16.96), C. cordata (11.87), B. davurica (11.66), B. costata (10.90), Styrax obassia (10.90) and A. koreana (10.41). Distribution of DBH P. densiflora had a formality distribution, suggesting a continuous domination of these species over the other species for the time being. In contrast, F. mandshurica appeared limited to the valley of the sheet and a higher frequency of young individuals, suggesting a continuous domination of these species the development of a climax forest terrain. This study showed the correlation between each community and the environment according to DCCA ordination. The A. koreana community predominated on the northern slope of the park in the high elevation habitats which had many O-M. F. mandshurica community predominated in the highest elevation habitats which had many Moisture, EX-Cation and T-N. The P. densiflora community mainly occurred on the southern slope of the park in the low elevation habitats which had few Moisture, O-M and T-N. The Q. serrata community and C. laxifiora community appeared on the park in the middle habitats.

• BMB Reports
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• 제52권4호
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• pp.259-264
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• 2019

Social requirements are needed for living in an aging society and individual longevity. Among them, improved health and medical cares, appropriate for an aging society are strongly demanded. Human cord blood-derived plasma (hUCP) has recently emerged for its unique anti-aging effects. In this study, we investigated brain rejuvenation, particularly olfactory function, that could be achieved by a systemic administration of young blood and its underlying mechanisms. Older than 24-month-old mice were used as an aged group and administered with intravenous injection of hUCP repetitively, eight times. Anti-aging effect of hUCP on olfactory function was evaluated by buried food finding test. To investigate the mode of action of hUCP, brain, serum and spleen of mice were collected for further ex vivo analyses. Systemic injection of hUCP improved aging-associated olfactory deficits, reducing time for finding food. In the brain, although an infiltration of activated microglia and its expression of cathepsin S remarkably decreased, significant changes of proinflammatory factors were not detected. Conversely, peripheral immune balance distinctly switched from predominance of Type 1 helper T (Th1) cells to alternative regulatory T cells (Tregs). These findings indicate that systemic administration of hUCP attenuates age-related neuroinflammation and subsequent olfactory dysfunction by modulating peripheral immune balance toward Treg cells, suggesting another therapeutic function and mechanism of hUCP administration.

• Asian-Australasian Journal of Animal Sciences
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• 제31권2호
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• pp.230-236
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• 2018

Objective: Two ex vivo experiments were conducted to verify the effect of barley grain (Nusrat cultivar) treated with alkaline compounds (AC) including alum, ammonium, and sodium hydroxide or cation-exchanged organic extracts (OE) prepared from alfalfa hay, sugar beet pulp and Ulva Fasciata, on extent and digestion of starch. Methods: In the first study, the in vitro first order disappearance kinetic parameters of dry matter (DM), crude protein (CP) and starch were estimated using a non-linear model ($D_{(t)}=D_{(i)}{\cdot}e^{(-k_d{\cdot}time)}+I$, where: $D_{(t)}$ = potentially digestible residues at any time, $D_{(i)}$ = potentially digestible fraction at any time, $k_d$ = fractional rate constant of digestion (/h), I = indigestible fraction at any time). In the second experiment, the ruminal and post-ruminal disappearance of DM, CP, and starch were determined using in situ mobile nylon bag. Results: Barley grains treated with alum and alfalfa extract had a higher constant rate of starch digestion (0.11 and 0.09/h) than others. Barley grain treated with OE had a higher constant rate of CP digestion and that of treated with AC had a higher constant rate of starch digestion (0.08 and 0.11/h) compared with those of the other treatments. The indigestible fraction of starch treated with alum and sugar beet pulp extract was higher than that of the control group (0.24 and 0.25 vs 0.21). Barley grain treated with AC and OE had significant CP disappearance in the rumen, post-rumen and total tract, and also starch disappearance for post-rumen and total tract compared with the untreated (p<0.001). Conclusion: This study demonstrated that AC and OE might have positive effects on the starch degradation of the barley grain. In addition, treating barley grain with alum and sugar beet pulp extract could change the site and extend digestion of protein and starch.

• 아시안잔디학회지
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• 제24권1호
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• pp.9-15
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• 2010

2008~2009 겨울 동안 강원도와 전라북도 소재 골프장에서 분리한 황색마름병원균(Rhizoctonia cerealis Van der Hoeven)과 설부갈색소립균핵병원균(이하 설부병원균)(Typhlua incarnata Lasch ex Fr.)에 대한 화본과 식물과 잔디 종(품종)의 저항성이 실내에서 평가되었다. 분리균주의 병원성 검정결과 대부분의 잔디와 화본과 식물에 병을 일으켰지만 균주간의 병원력 차이도 발견되었다. 황색마름 병균은 잔디의 지제부위를 통해 감염하여 연한 갈색의 원형 반점 증상을 보이다가 진전되면 적색을 띄다가 결국 진한 갈색의 증상으로 나타났다. 설부병 증상은 수침형 반점으로 시작해서 전체 식물체를 갈색으로 고사시켰는데, 대부분 감염부위에서 흰색의 균사체가 식물체와 토양을 뒤덮었고 진전되면 다양한 크기의 갈색과 검은색의 독특한 균핵을 형성하였다. 병 발생은 습실기간이 길어질수록 증가하는 경향이었다. 화본과 작물과 잔디의 종(품종)간에는 병원균의 병원력에 차이도 나타났으며 두 병원균에 대해 양적인 차이를 보였다.

• 한국가금학회지
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• 제24권2호
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• pp.73-83
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• 1997

This study was conducted to investigate the influence of dietary $\omega$-fatty acids on fatty acids composition and storage characteristics in meat samples of spent hens. Spent hens were randomly assigned to one of the four dietary treatments : 1) Control (commercial feed), 2) T1 (commercial feed supplemented with 10% olive oil, 3) T2 (commercial feed with 10% canola oil), and 4) T3 (commercial feed with 10% sardine oil). They were fed one of the experimental diets for three weeks and slaughtered. The meat samples were stored at 4 ${\pm}$ 1 ˚C The storage characteristics and fatty acid contents were analyzed for meat samples stored over a period of 1, 3, 5, 7 and 9 days. The pH of all treatments significantly increased during the storage periods(P<0.05). The per-oxide values (POV) of all treatments were significantly increased up to 5 days ; after that the POV decreased significantly (P<0.05). The POV of treated groups were significantly higher than those of the Control in the thigh meat(P<0.05). The TBARS showed the highest POV among all treatments. Although the breast meat tended to he lower in POV than the thigh meat, no significant difference was detected between the two meats. The TBARS(thiobarbituric acid reactive substances) of all treatments were significantly increased as the storage period extended(P<0.05). After 3 days, the TB ARS of oil-treated groups were aignificantly higher than that of the Control (P<0.05). The T3 showed the highest TBARS among all treatments (P<0.05). The TBARS of the breast meat was lower than that of the thigh, but no statistical difference was found be- tween them. The unsaturated fatty acid content of the breast and thigh meats in all treatments were slightly decreased as the storage period extended. The oleic acid was higher in Ti, and the linoleic acid and linolenic acid were higher in T2 than the other treatments. The eicosapentaenoic acid and docosahexaenoic acid were higher in T3 than the other treatments. The unsaturated fatty acid contents of the breast meat were slightly lower than those of the thigh meat. The n-6 fatty acid contents of the breast and thigh meats were slightly increased as the storage periods ex-tended. The n-3 fatty acid content of T3 was the highest among all treatments. The n-6 fatty acid content of breast meat was lower than that of thigh meat. The n-6 fatty acid content of the breast meat was slightly lower than that of the thigh meat.

• Journal of Chest Surgery
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• 제20권1호
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• pp.81-91
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• 1987

During the period of 10 years from July, 1976 to July, 1986, 154 cases of primary carcinoma of the lung - by the cell type, stage, operability, and survival rate in the resectable cases - are analyzed at the Dept. of Thoracic Surgery, Paik Hospital in Seoul. The results are as follows: 1] Histopathological types are squamous cell carcinoma 49% [76 cases], adenocarcinoma 25% [39 cases], undifferentiated large cell carcinoma 9% [14 cases], undifferentiated small cell carcinoma 6% [9 cases], bronchioloalveolar carcinoma 4% [6 cases] and adenosquamous carcinoma 3% [4 cases]. 2] Peak incidence is observed in the 4th decade of life [33%], then 5th [29%] and 3rd [21%] respectively. Male to female ratio is 4 to 1. 3] Evidence of inoperability is observed in 64% [99 cases] by clinical staging workup. Thirty six percent [55 cases] were operated. Of these, post-surgical stage I was 5% [3 cases], stage II, 64% [35 cases] and stage III, 31% [17 cases]. Among total 17 cases of stage III, 14 cases were unresectable with evidence of T2N2M0, while 3 cases were resectable. Resectability is 27%, [41 cases] from the total number of 154 cases. And the resectability for the ex 55 cases is 75% [41 cases]. 4] By cell type, highest resectabitity is the squamous cell carcinoma, 49% [20 cases]. Adenocarcinoma is 32% [13 cases] and bronchioloalveolar, 12% [5 cases]. 5] Survival rate is evaluated for 38 cases of 41 resectable stage I, II and III. Overall 5 year survival rate is 24%, 3 year 32% and 10 year 8%. Survival rate in stage II for 5 year is 25%. In squamous cell type for, 5 year is 42%. Authors believe when surgeons continuous effort of early detection is met with patients early visit, 5 year survival rate for the stage I K II resectable patients will improve more effectively. As well, When the efforts are added to combined modality with radiotherapy and chemotherapy for the stage III selected cases of non-small cell carcinoma patients, the enhancement in survival rate is expected.

• 동의신경정신과학회지
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• 제17권3호
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• pp.67-75
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• 2006

This Study is attempted to analyze Minnesota Multiphasic Personality Inventory responses to Vertigo patients and remedial value of Oriental medicine treatment. Methods: 24 Vertigo patients and 28 control group were tested by MMPI and QSCCII. It is analyzed by cluster analysis, one-way ANOVA, chi-square test, t-test, Duncan method is used as ex-post test. Results and Conclusions: 1. The MMPI scores of Vertigo patients were elevated in Hs, Hy clinical scales, 1-3 profile type, it is profile of conversional neurosis. In this case body condition where the psychological problem will get conversion is a notable feature. 2. All of the profiles can be classified three types of profile. Group 1(33.3%) showed 1-3-2 profile type and elevated Pt. scale, suggesting mainly depressive neurosis in the department of neuropsychiatry. Group 2 (37.5%) showed a normal profile. Group 3(29.2%) showed 1-3 profile type it is profile of conversional neurosis. With this result it is indicated that 62.5% Vertigo patients are related to emotional difficulties. 3. There was to a remedial value for the Vertigo patients, before treating from VAS score 10.00 after treating at VAS score 4.13. From this study, we know the possibility the Oriental medicine register remedial value for the Vertigo patients.

• Biomolecules & Therapeutics
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• 제10권1호
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• pp.19-24
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• 2002

The effects of a newly synthesized $H^+/K^+$ ATPase inhibitor,1-(2-methyl-4-methoxypheny)-4-[(3-hy-droxypropyl)amino] -6-methyl-2,3-dihydropyrrolo (3,2-c) quinoline (DBM-819) , on the central nervous system, isolated smooth muscle, cardiovascular and digestive systems and renal function were investigated in various experimental animals. Oral administration of DBM-819 had no effect on the central nervous system except body temperature of mice slightly decreased at doses of 15 and 50 mg／kg. DBM-819 produced a moderate analgesic effect in acetic acid-induced writhing test in mice at 50 mg／kg (p.o.). In conscious rats, DBM-819 (15 and 50 mg／kg, p.o.) showed a slight increase in blood pressure and a small decrease in heart rate. DBM-819 had an significant effect on agonist-induced contraction of guinea pig ileum at $1.5{\times}10^{-5}g/ml.$ No significant effect of DBM-819 (5 and 15 mg／kg, i.p) on urinary volume or urinary excretion of $Na^+,\;K^+$ and Cl- was observed in rats. DBM-819 had no significant effect on intestinal transport of a semisolid meal in mice at 15 and 50 mg／kg (p.o.). These findings suggest that DBM-819 exerts no significant pharmacological effects on the central nervous system and renal function at 15 mg／kg (p.o.), but produces some effects on the smooth muscle and circulatory system.

• 지역사회간호학회지
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• 제15권2호
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• pp.277-288
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• 2004

Purpose: This study was to provide basic information for preventing high school students from smoking by examining their actual smoking condition and their knowledge and attitude about smoking. Method: The subjects were 515 students selected from six(6), high schools in Jecheon. Data were collected using a questionnaire from the 1st to the 17th of December 2002. The author prepared the tool by modifying the scale of knowledge and attitude about smoking developed by Moon(2001). Data were analyzed with SPSS/WIN program using frequencies, percentages, $x^2$-test, t-test, ANOVA. Duncan test and Pearson's correlation coefficient. Result: 1. The percentage of ex-smoking students was 29.9% of male students and 18.6% of female ones. The percentage of currently smoking students was 23.9% of male students and 3.0% of female ones. The percentage of non-smoking students was 46.2% of male students and 78.4% of female ones, 2. There were not significant differences in smoking knowledge according to smoking status in male and female students. 3. There were significant differences in smoking attitude according to smoking status in male(F=32.70, p=.000) and female(F=11.15, p=.000) students. 4. In smoking status according to general characteristics, there were significant differences according to the type of school($x^2$=32.93, p=.000), grade($x^2$=11.91, p=.018), educational level of the father($x^2$=30.52, p=.000) and the mother($x^2$=14.23, p=.027), monthly allowance($x^2$=17.19, p=.028), harmony of family members($x^2$=15.23, p=.019), school life($x^2$=26.96, p=.00l) and school record($x^2$=30.24, p=.000). 5. In smoking status according to smoking-related characteristics, there were significant differences according to experience in cigarette purchase($x^2$=150.04. p=.000), experience in errands for cigarette($x^2$=20.00, p=.000), knowledge of cigarette price($x^2$=72.52, p=.000), close friends' smoking($x^2$=107.41. p=.000) and smoking of brothers and sisters($x^2$=16.97, p=.002). 6. There were significant correlation between knowledge and attitude about smoking in the whole students(r=.337. p=.000), ex-smokers(r=.324. p=.000), non-smokers(r=.369. p=.000) but there was not a significant correlation between knowledge and attitude about smoking in current smokers(r=.128. p=.30l). Conclusion: Smoking prevention education should considered students' smoking status. Current smokers need smoking prevention education aiming to change their attitude toward smoking in order for them to reduce smoking and to practice smoking cessation.

• Tuberculosis and Respiratory Diseases
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• 제59권4호
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• pp.406-412
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• 2005

연구배경 : 최근 말초혈액을 결핵균 특이 항원으로 자극후 분비되는 $IFN-{\gamma}$ 를 측정하는 $QuantiFERON^{(R)}-TB$ Gold (QFT) 와 T $SPOT-TB^{(R)}$(SPOT) 검사가 임상에서 잠복결핵의 진단에 상품화되어 사용되고 있다. 그러나 이전에 시행한 투베르쿨린 검사가 상기 체외 $IFN-{\gamma}$ 검사의 위양성을 유발할 수 있는 가능성에 대해서는 아직 발표된 자료가 없다. 방 법 : 과거 결핵치료력 또는 환자 접촉력이 없는 46명의 15세 남자 고등학생을 대상으로 하였다. 혈액을 채취하여 $IFN-{\gamma}$ 검사를 시행하고, 이단계 TST를 시행하였다. 첫 번째 검사에서 $IFN-{\gamma}$ 검사와 TST가 모두 음성인 학생을 대상으로 하여 2개월 째에 TST, 2개월, 4개월 째에 QFT, 그리고 2개월 째에 SPOT 검사가 반복 시행되었다. 결 과 : TST 경결 크기의 평균값은 $3.1{\pm}5.4mm$ (범위: 0-20)였고, 이단계 TST에서 최종 13/46명(28.3%)이 양성 결과를 나타내었다. SPOT검사는 9명(19.6%)에서 양성이었으며 QFT는 1명(2.2%)에서만 양성이었다. 첫 $IFN-{\gamma}$ 검사와 TST에서 모두 음성인 학생 24명에서 2개월에 시행한 TST 모두 음성이었다. 2개월(23명) 및 4개월(25명)에 시행한 QFT 검사는 모두 음성이었다. 2개월에 SPOT 검사를 시행한 23명 중 1명(4.3%)에서 약양성 결과를 보였다. 결 론 : 두 가지 체외 $IFN-{\gamma}$ 검사의 결과에 일부 차이가 있었으나 2개월 및 4개월 이전에 시행된 TST가 체외 $IFN-{\gamma}$ 검사결과에 영향을 미치지 않음을 알 수 있었다.