• Title/Summary/Keyword: $T_EX$

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Anti-inflammatory Effect of Isaria sinclairii Glycosaminoglycan in an Adjuvant-treated Arthritis Rat Model

  • Ahn, Mi Young;Jee, Sang Duck;Hwang, Jae Sam;Yun, Eun Young;Ahn, Kwang Seok;Kim, Yeong Shik
    • Toxicological Research
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    • v.29 no.3
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    • pp.195-201
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    • 2013
  • The anti-inflammatory effects of glycosaminoglycan (GAG) derived from Isaria sinclairii (IS) and of IS extracts were investigated in a complete Freund's adjuvant (CFA)-treated chronic arthritis rat model. Groups of rats were treated orally with 30 mg/kg one of the following: [1] saline control, extracts of [2] water-IS, [3] methanol-IS, [4] butanol-IS, [5] ethyl acetate-IS, or [6] Indomethacin(R) as the positive control for a period of two weeks. The anti-paw edema effects of the individual extracts were in the following order: water-IS ex. > methanol ex. > butanol ex. > ethyl acetate ex. The water/methanol extract from I. sinclairii remarkably inhibited UV-mediated upregulation of NF-${\kappa}B$ activity in transfected HaCaT cells. GAG as a water-soluble alcohol precipitated fraction also produced a noticeable anti-edema effect. This GAG also inhibited the pro-inflammatory cytokine levels of prostaglandin $E_2$-stimulated lipopolysaccharide in LAW 264.7 cells, cytokine TNF-${\alpha}$ production in splenocytes, and atherogenesis cytokine levels of vascular endothelial growth factor (VEGF) production in HUVEC cells in a dose-dependent manner. In the histological analysis, the LV dorsal root ganglion, including the articular cartilage, and linked to the paw-treated IS GAG, was repaired against CFA-induced cartilage destruction. Combined treatment with Indomethacin(R) (5 mg/kg) and IS GAG (10 mg/kg) also more effectively inhibited CFA-induced paw edema at 3 hr, 24 hr, and 48 hr to levels comparable to the anti-inflammatory drug, indomethacin. Thus, the IS GAG described here holds great promise as an anti-inflammatory drug in the future.

IN VITRO MICRO-SHEAR BOND STRENGTH OF FIVE COMPOSITE RESINS TO DENTIN WITH FIVE DIFFERENT DENTIN ADHESIVES (미세-전단 결합 강도 시험을 이용한 상아질 접착제와 수복용 복합 레진의 호환성에 관한 연구)

  • Chung, Jin-Ho;Roh, Byoung-Duck
    • Restorative Dentistry and Endodontics
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    • v.29 no.4
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    • pp.353-364
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    • 2004
  • The purpose of this study was to compare and to evaluate the combination use of 5 kinds of dentin adhesive systems and 5 kinds of composite resins using micro-shear bond test. Five adhesive systems (Prime & Bond NT (PBN). Onecoat bond (OC), Excite (EX), Syntac (SY), Clearfil SE bond (CS)) and five composite resins (Spectrum (SP), Synergy Compact (SC), Tetric Ceram (TC), Clearfil AP-X (CA), Z100 (Z1)) were used for this study ($5{\;}{\times}{\;}5{\;}={\;}25group$, n =14/group). The slices of horizontally sectioned human tooth were bonded with each bonding system and each composite resin, and tested by a micro-shear bond strength test. These results were analyzed statistically. The mean micro-shear bond strength of dentin adhesive systems were in order of CS (22.642 MPa), SY (18.368 MPa), EX (14.599 MPa). OC (13.702 MPa). PBN (12.762 MPa). The mean bond strength of self-etching primer system group (CS, SY) in dentin was higher than that of self-priming adhesive system groups (PBN, EX, OC) significantly (P<0.05). The mean bond strength of composite resins was in order of SP (19.008 MPa), CA (17.532 MPa). SC (15.787 MPa), TC (15.068 MPa). Z1 (14.678 MPa). Micro-shear bond strength of SP was stronger than those of other composite resins significantly (P < 0.05). And those of TC and Z1 were weaker than other composite resins significantly (P < 0.05). No difference was found in micro-shear bond strength of composite resin in self-etching primer adhesive system groups (CS, SY) statistically. However, there was significant difference of micro-shear bond strength of composite resin groups in self-priming adhesive systems group (PBN, EX, OC). The combination of composite resin and dentin adhesive system recommended by manufacturer did not represent positive correlation. It didn't seem to be a significant factor.

Tuning of Dual-input PSS and Its Application to 612 MVA Thermal Plant: Part 2-Field Testing and Performance Verification (다중입력 PSS 튜닝 방법과 612 MVA 화력기 적용: Part 2-현장 튜닝시험 및 성능검증)

  • Kim, Dong-Joon;Moon, Young-Hwan;Kim, Sung-Min;Kim, Jin-Yi;Hwang, Bong-Hwan;Cho, Jong-Man
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.58 no.4
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    • pp.665-670
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    • 2009
  • The second paper, Part 2, describes the field testing of IEEE type PSS2A EX2000 excitation in the Dangjin 612 MVA T/P #4. The final PSS gain, $K_s$, was determined by inputting 2%-step signals into AVR at a loading of 500MW and increasing $K_s$, from 0 to 15 in increments of 3. After the field testing, the measured data was also analyzed by Discrete Fourier Transformation(DFT) analysis, and the model parameters of generation system were verified by replicating the measured data with the transient stability program.

Tuning of Dual-input PSS and Its Application to 612 MVA Thermal Plant: Part 1-Tuning Methology of IEEE Type PSS2A Model (다중입력 PSS 튜닝 방법과 612 MVA 화력기 적용: Part 1-IEEE PSS2A 튜닝 방법)

  • Kim, Dong-Joon;Moon, Young-Hwan;Kim, Sung-Min;Kim, Jin-Yi;Hwang, Bong-Hwan;Cho, Jong-Man
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.58 no.4
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    • pp.655-664
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    • 2009
  • This paper, Part 1, describes the effective dual-input PSS parameter design procedure for the IEEE Type PSS2A against the Dangjin 612 MVA thermal plant's EX2000 excitation system. The suggested tuning technique used the model-based PSS tuning method and consisted of three steps: 1) generation system modeling; 2) determination of PSS2A model parameters using linear, time-domain transient and 3-phase simultaneous analyses, and 3) field testing and verification, which are described in Part 2. The effective PSS2A model parameters of EX2000 system in the Dangjin T/P #4 were designed according to the suggested procedure, and verified by using three analyses.

A new distribution record of Trichosanthes cucumeroides (Ser.) Maxim. ex Franch. & Sav. (Cucurbitaceae) in Korea

  • KIM, Kyeonghee;KIM, Jung-Hyun;CHO, Yang-Hoon;KIM, Seok-Soon;KIM, Jin-Seok
    • Korean Journal of Plant Taxonomy
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    • v.50 no.3
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    • pp.356-360
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    • 2020
  • A new distribution of Trichosanthes cucumeroides (Ser.) Maxim. ex Franch. & Sav. is discovered in Korea. This species was collected from forest margins on Ando Island, Ando-ri, Nam-myeon, Yeosu-si, in Jeollanam-do. T. cucumeroides is clearly distinguished from other species of the genus by having three- or five-lobed leaf blades, linear-lanceolate and minute bracts with entire margins, and oblong to triangular-ovoid seeds. Here, we provide precise description, a taxonomic key to the Korean Trichosanthes species, illustrations, and photographs of its habitat. The Korean name for the species is established as 'Bul-geun-ha-neul-ta-ri' considering the reddish color of its fruit.

An Exploratory Study on the Causal-effect Relationship between Valuation and Performance in Ventures (벤처기술평가와 경영성과의 인과관계에 관한 탐색연구)

  • Yang, Dong-Woo
    • 한국벤처창업학회:학술대회논문집
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    • 2006.11a
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    • pp.61-85
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    • 2006
  • The Purpose of this study is to prove empirically the relationship between ventures' technology valuation and performance, while considering the uniqueness of Korean firms. We use technology valuation index, marketability valuation index, business valuation index as ex-ante independent variables, use firm's performance(sales, asset, operating income ratio, net income ratio etc) as ex-post dependent variables. Parametric analysis such as Paired T-test, ANOVA are applied in this paper. The results of Empirical analysis is summarized as follows. Firstly, operating income ratio and net income ratio are different in portfolios classified by technology valuation index. Secondly, the growth rate of operating income is different in portfolios classified by technology valuation index. Finally, this study has shown that technology valuation index has possibility which it use the predictive variables of ventures' performances.

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Studies on the Morphology and the Chemotaxonomy of Citrus Plants Native to Je Ju Island and on its Application (II) -On the Chemical Components of Citrus platymamma Hort. ex Tanaka- (제주도 재래감귤의 식물학적 특성과 이용에 관한 연구 (II) -병귤(甁橘)의 성분연구-)

  • Kim, Chang-Min;Huh, In-Ok;Han, Dae-Suk
    • Korean Journal of Pharmacognosy
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    • v.10 no.2
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    • pp.85-87
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    • 1979
  • 제주도(濟州道) 재래감귤인 병귤(甁橘) Citrus platymamma $H_{ORT}$. ex $T_{ANAKA}$의 엽(葉), 과피(果皮), 수피(樹皮)의 클로로포롬 가용부(可容部)에서 무색침장정(無色針狀晶), $C_{10}H_{10}O_{4}$, mp $139{\sim}140^{\circ}c$을 단리(單利)하고 이화학적(理化學的) 성상(性狀)및 UV, IR, NMR, Mass spectra를 이용하여 그 화학구조(化學構造)를 구명(究明)한바 1,4-benzenedicar-boxylic acid dimethyl ester이었다. 또 과피(果皮)의 수용부(水溶部)에서 단리(單利)한 2개의 flavonoid 배당체(配糖體)는 그 이화학적(理化學的)인 성상(性狀) 및 IR-spectrum으로 보아 naringin hesperidin이었다.

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An Empirical Study on the Relationship between Technology Valuation and Performance in Ventures (벤처의 기술평가와 경영성과의 관계에 관한 연구)

  • Yang, Dong-Woo
    • Knowledge Management Research
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    • v.4 no.1
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    • pp.21-33
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    • 2003
  • The Purpose of this study is to prove empirically the relationship between technology valuation and performance in Ventures, while considering the uniqueness of Korean firms. We use technology score, marketability score, business attractiveness score as ex-ante independent variables, use firm's performance(sales, asset, operating income ratio, net income ratio etc) as ex-post dependent variables. Parametric analysis such as Paired T-test, ANOVA are applied in this paper. The results of Empirical analysis is summarized as follows. Firstly, operating income ratio and net income ratio are different in portfolios classified by technology score. Secondly, the growth rate of operating income is different in portfolios classified by technology score. Finally, this study has shown that technology score has possibility which it use the predictive variables of firm performances.

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The Implementation of sensor network and CMS server in R.Box (R.Box에서의 센서 네트워크와 CMS 서버 구현)

  • Kim, JinGyeong;Ra, SangYong;Choi, JaeHong;Lee, JunDong
    • Proceedings of the Korean Society of Computer Information Conference
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    • 2018.01a
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    • pp.77-78
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    • 2018
  • 인터넷과 사물의 결합이 급속도로 진행되며 IoT(Internet of Things, 사물인터넷)의 활성화 역시 앞당겨지고 있다. 최근 IoT 기술 및 서비스와 관련하여 가정, 공장 등의 다양한 장소와 공기청정기, 체온계 등의 제품에도 IoT 기술이 접목된 서비스가 제공되고 있다. 본 논문에서는 일반목적의 IoT 허브인 R.Box의 센서 네트워크와 R.Box와 센서를 통제, 제어하며 데이터 저장과 간단한 통계를 확인할 수 있는 CMS(Content Management System) 기능을 하는 서버 구현에 대해 설명한다. R.Box는 라즈베리 파이를 이용해 제작되었으며 사용자는 서버에 접속해 R.Box와 센서의 정보, 측정된 값을 확인하고 수정, 삭제, 검색 등의 기능을 사용할 수 있다.

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Data Build-up for the Construction of Korean Specific Greenhouse Gas Emission Inventory in Livestock Categories

  • Won, S.G.;Cho, W.S.;Lee, J.E.;Park, K.H.;Ra, C.S.
    • Asian-Australasian Journal of Animal Sciences
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    • v.27 no.3
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    • pp.439-446
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    • 2014
  • Many studies on methane ($CH_4$) and nitrous oxide ($N_2O$) emissions from livestock industries have revealed that livestock production directly contributes to greenhouse gas (GHG) emissions through enteric fermentation and manure management, which causes negative impacts on animal environment sustainability. In the present study, three essential values for GHG emission were measured; i.e., i) maximum $CH_4$ producing capacity at mesophilic temperature ($37^{\circ}C$) from anaerobically stored manure in livestock category ($B_{0,KM}$, Korean livestock manure for $B_0$), ii) $EF_{3(s)}$ value representing an emission factor for direct $N_2O$ emissions from manure management system S in the country, kg $N_2O-N$ kg $N^{-1}$, at mesophilic ($37^{\circ}C$) and thermophilic ($55^{\circ}C$) temperatures, and iii) $N_{ex(T)}$ emissions showing annual N excretion for livestock category T, kg N $animal^{-1}$ $yr^{-1}$, from different livestock manure. Static incubation with and without aeration was performed to obtain the $N_2O$ and $CH_4$ emissions from each sample, respectively. Chemical compositions of pre- and post- incubated manure were analyzed. Contents of total solids (% TS) and volatile solid (% VS), and the ratio of carbon to nitrogen (C/N) decrease significantly in all the samples by C-containing biogas generation, whereas moisture content (%) and pH increased after incubation. A big difference of total nitrogen content was not observed in pre- and post-incubation during $CH_4$ and $N_2O$ emissions. $CH_4$ emissions (g $CH_4$ kg VS-1) from all the three manures (sows, layers and Korean cattle) were different and high C/N ratio resulted in high $CH_4$ emission. Similarly, $N_2O$ emission was found to be affected by % VS, pH, and temperature. The $B_{0,KM}$ values for sows, layers, and Korean cattle obtained at $37^{\circ}C$ are 0.0579, 0.0006, and 0.0828 $m^3$ $CH_4$ kg $VS^{-1}$, respectively, which are much less than the default values in IPCC guideline (GL) except the value from Korean cattle. For sows and Korean cattle, $N_{ex(T)}$ values of 7.67 and 28.19 kg N $yr^{-1}$, respectively, are 2.5 fold less than those values in IPCC GL as well. However, $N_{ex(T)}$ value of layers 0.63 kg N $yr^{-1}$ is very similar to the default value of 0.6 kg N $yr^{-1}$ in IPCC GLs for National greenhouse gas inventories for countries such as South Korea/Asia. The $EF_{3(s)}$ value obtained at $37^{\circ}C$ and $55^{\circ}C$ were found to be far less than the default value.