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Ebstein 기형에 인공판윤을 이용한 금속형 St. Jude Medical 인공판막 대치술 (Ebstein`s anomaly ; St. Jude Medical valve replacement using partial artificial annulus formation - A Case Report -)

  • 이종국;조재민
    • Journal of Chest Surgery
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    • 제25권8호
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    • pp.826-831
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    • 1992
  • Ebstein`s anomaly is characterized by a downward displacement of a malformed tricuspid valve, The ideal surgical management of Ebstein`s anomaly is not yet established. Recently we experience one case of Ebstein`s anomaly, which was treated sussessfully by partial artificial annulus formation, and tricuspid valve replacement with St. Jude Medical valve. We have achieved excellent results with mechanical valve replacement and partial artificial annulus formation using wessex pericardial patch. On follow up for 4 years, the patient is well and in functional class I.

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Building safe communities: A dynamic simulation study

  • Cho, Sung-Sook;Gillespie David F.;Robards Karen Joseph
    • 한국시스템다이내믹스연구
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    • 제7권1호
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    • pp.213-228
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    • 2006
  • This paper reports the results of a study designed to understand and facilitate disaster mitigation for communities located in low frequency/high magnitude earthquake zones. The study is based on a small town located near the New Madrid Fault Zone and is therefore at significant earthquake risk. A system dynamics model describes the variables and policies governing the distribution of building safety over time. Data from this town is used to establish a 25-year baseline. Simulations are run to demonstrate the consequences of different building policies.

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복합 살모넬라 타이피무리움 고스트 백신의 마우스 구강 투여에 의한 면역 응답 (Immune Responses of BALB/c Mice Administrated via Oral Route to a Combined Salmonella Typhimurium Ghost Vaccine)

  • 김판길;하연조;이수만;김삼웅;갈상완
    • 생명과학회지
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    • 제25권11호
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    • pp.1197-1203
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    • 2015
  • 살모넬라 타이피무리움 JOL389와 χ3339는 마우스에 강한 독력을 가진 균주들이며, χ8554는 χ3339로부터 유도되었다. 고스트 카세트를 운반하는 플라스미드 pMMP184가 제조된 후에, BALB/c 마우스의 구강 경로를 경유하여 투여되었다. 총 IgG의 함량 변화는 χ8554 고스트 세포의 부스팅으로 발현 함량이 낮게 나타났지만, 3차 접종의 2주 경과 후, 6주차에서 증가되는 양상을 보였다. 그러나, 혼합 백신 그룹인 JOL389/χ8554 그룹에서는 총 IgG의 함량이 일차 접종 후 2주차부터 상승되는 경향을 보였고, 추가접종이 진행되므로써 많은 상승 폭을 나타내었다. 총 IgG의 함량은 백신 접종 후 10주차에서 χ8554그룹에 비교하여 JOL389/χ8554은 8배 이상 높은 것으로 관찰되었다. IgG1, IgG2a, 분비IgA의 함량은 백신화 후 4주차에서 상승되었다. 독력 살모넬라 타이피무리움 χ3339로 도전실험결과, χ8554 [pMMP184]과 χ8554 [pMMP184]/JOL389은 대조구에 비교하여 50% 이상의 보호효과가 관찰되었다. 이들 결과는 χ8554 [pMMP184]/JOL389은 χ8554 [pMMP184]보다 더 높은 면역 응답을 유도하는 것이 가능한 것으로 추정된다.

한국 송지천에서 저서성대형무척추동물의 종조성과 이를 이용한 수질 평가 (Species Composition of Benthic Macroinvertebrates and Water Evaluation Using Their Species in the Songji River in Korea)

  • 이병룡;허만규
    • 생명과학회지
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    • 제29권5호
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    • pp.580-587
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    • 2019
  • 저서성대형무척추동물은 수질 평가를 위해 다년간 이용되었다. 본 연구는 한국 송지천에서 저서성대형무척추동물을 이용하여 이 하천의 수질을 평가하고자 수행되었다. 동정된 동물은 3문 5강 12목 18과 20종 447개체였다. 집모기류(Culicini sp.)가 가장 우점종이었고(203개체), 두번째 우점종은 집파리(Musca do­mestica)였다. 다양한 생태학적 척도로 수질의 상태를 평가하였다. 전체 생태 점수(total ecological score of benthic macroinvertebrate community, TESB)은 17(St. D)에서 41(St. A)으로 평균은 29였다. St. A에서 부수성 지수와 저서성 대형무척추동물생태 점수(ESB)는 II 등급으로 빈부수성, 수질은 약간 만족이며 보호가 요청되는 수질에 해당되었다. 저서성동물지수(benthic macroinvertebrate index, BMI)은 25.207(St. C)에서 39.348(St. A)까지 이며 평균은 31.810였다. St. C와 St. D의 하천 상태 평가는 강부수성이며 민감종이 결여되어 있었다. 다양도를 나타내는 Shannon-Weaver index (H')는 1.288(St. D)에서 2.250(St. A)였다. H'에 근거한 부수성 정도는 St. A에서는 ${\beta}$-중부수성이었으며 나머지 지점은 ${\alpha}$-중부수성이었다. 지리적 밀도는 1.229(St. A)에서 2.071(St. D)으로 평균은 1.582였다. 송지천에서 사용한 무척추동물을 이용한 여러 수질의 척도는 한국 내 다른 하천에서도 적용할 수 있을 것이다.

구내방사선사진상의 이공에 관한 연구 (A RADIOGRAPHIC STUDY OF MENTAL FORAMEN IN INTRAORAL RADIOGRAPHS)

  • 손정익;최갑식
    • 치과방사선
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    • 제25권2호
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    • pp.501-511
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    • 1995
  • The purpose of this study was to evaluate the position and shape of mental foramen in periapical radiographs. For this study, periapical radiographs of premolar areas were obtained from the 200 adults. Accordingly, the positional and shape changes of mental foramen were evaluated. The authors obtained radiographs according to changes in radiation beam direction in periapical radiographs of premolar areas, and then evaluated the positional and shape changes of mental foramen. The following results were obtained: 1. Shapes of mental foramen were observed elliptical(34.3%), round or oval(28.0%), unidentified(25.5%) and diffuse(12.2%) type in descending order of frequency. 2. Horizontal positions of mental foramen were most frequently observed at the 2nd premolar area(55.3%), the area between the 1st premolar and 2nd premolar(39.6%), the area between the 2nd premolar and 1st molar(3.4%), the 1st premolar area(1.0%), the area between the canine and 1st premolar(0.7%) in descending order of frequency. 3. Vertical positions of mental foramen were most frequently observed at the inferior to apex(67.1%), and at apex(24.8%), overlap with apex(6.4%), superior to apex(1.7%) in descending order of frequency. 4. Shapes of mental foramen were more obviously observed at the upward 10° positioned periapical radiographs. And according to the changes of horizontal and vertical position, they were observed similar to normally positioned periapical radiographs.

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Drug Utilization Review 시행 전후 3차 의료기관에서의 노인주의약품 외래처방 현황 분석 (The Evaluation of Drug Utilization Review on Potentially Inappropriate Medications for Elderly Patients in a Tertiary Hospital)

  • 조여향;김광준
    • 한국임상약학회지
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    • 제29권1호
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    • pp.25-32
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    • 2019
  • Objective: South Korea made a list of potentially inappropriate medications (PIMs) for elderly patients in 2015 and has prompted medical professionals to prescribe proper medication by using the drug utilization review (DUR) system. It has been three years since the system was introduced, but related studies have rarely been conducted. This study aimed to evaluate the effect of the DUR system on the prescription of PIMs for elderly patients. Methods: The data on the prescription of PIMs for elderly patients (${\geq}65$ years) who received medical treatment between March 1st and May 31st in 2015 (before introduction of the DUR system) and who received medical treatment between March 1st and May 31st in 2018 (after introduction of the DUR system) were retrospectively collected from electronic medical records. Results: The prescriptions of PIMs decreased from 3,716 (7.7%) to 3,857 (6.9%) (p < 0.001). The prescription of escitalopram and paroxetine, among selective serotonin reuptake inhibitors, increased significantly, and that of short-acting benzodiazepines also increased significantly from 454 (0.93%) to 624 (1.2%). Conclusion: Prescription of PIMs for elderly patients significantly decreased (p < 0.001) after the DUR system was introduced. Further expanded studies of PIMs need to be conducted for the safety of elderly patients.

병원 전 12-Lead ECG 측정을 통해 진단된 이형성 협심증 1례 (Variant angina diagnosed on pre-hospital 12-lead electrocardiogram: A case report)

  • 김지원;기은영
    • 한국응급구조학회지
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    • 제25권1호
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    • pp.243-249
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    • 2021
  • A decrease in coronary blood flow leads to an imbalance between the supply of oxygen to the myocardium and its demand, and reversible or irreversible damage to the myocardium could occur depending on the severity of the resultant ischemia and the duration of the imbalance. This imbalance results in a cascade of ischemic reactions in the following order: metabolic abnormalities, diastolic dysfunction, systolic dysfunction, and electrocardiogram changes. Variant angina is caused by the closure of the coronary artery due to reversible coronary artery spasm, resulting in myocardial ischemia and subsequent chest pain as a clinical symptom. Variant angina may be observed as ST segment elevation in electrocardiogram measured when present in chest pain. However, 12-lead electrocardiogram performed after the patient's chest pain resolves does not help in the diagnosis. Since the duration of chest pain appears to be <15 minutes, it is important to perform the 12-lead electrocardiogram when clinical symptoms are present. If nitroglycerin is administered without performing 12-lead electrocardiogram by 119 pre-hospital paramedics, the chest pain would be resolved, making it impossible to identify changes in the ST segment. Before administration of nitroglycerin, changes in the ST segment must be recorded by performing 12-lead electrocardiogram.

단원형배열안테나와 공간분할테이블을 이용한 방향탐지 및 추적 (Direction Finding and Tracking using Single-Ring Circular Array Antenna and Space Division Table)

  • 박현규;우대웅;김재식;박진성
    • 한국군사과학기술학회지
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    • 제25권2호
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    • pp.117-124
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    • 2022
  • Single-ring circular array antennas can be applied to direction finding systems in order to use nose-section in other purposes, and the interferometry is a proper direction finding method to those systems. We usually make the interferometer baseline long enough to achieve good angular accuracy. However, an interferometer with baseline longer than a half-wavelength has the ambiguity problem. In this paper, we present a novel method for solving the ambiguity problem in interferometry systems. This technique is based on the amplitude comparison method and the space division table, and it can place a target within the angular region in which the ambiguity problem does not occur by roughly estimating direction-of-arrival. The Monte Carlo simulation results show that proposed method can effectively remove the ambiguity problem in the system.