• 대한전기학회논문지:전기물성ㆍ응용부문C
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• 제48권1호
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• pp.12-17
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• 1999

$MgIn_2Se_4 and MgIn_2Se_4 : Ni^{2+}$ single crystals were grown in the rhombohedral structure by the chemical transport reaction (C.T.R.) method using iodine as a transport agent. The optical absorption measured near the fundamental band edge showed that the optical energy band structure of these compounds had a direct band gap. The fundamental absorption band edge of these single crystals shift to a shorter wavelength region by decreasing temperature and the temperature dependence of the optical energy gaps in these compounds satisfy Varshni equation. The impurity optical absorption peaks due to nickel are observed in $MgIn_2Se_4 and MgIn_2Se_4 : Ni^{2+}$ single crystal. These impurity optical absorption peaks can be attributed to the electronic transitions between the split energy levels of $Ni_{2+}$ ions located at $T_d$ symmetry site of $MgIn_2Se_4$ host lattice. In the hotoluminescence spectrum of the single crystal at 10 K, a blue emission with a peak at 687nm and a green emission with a peak at 815nm for the $MgIn_2Se_4$ single crystal were observed.

• 대한예방한의학회지
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• 제6권2호
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• pp.66-85
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• 2002

Traditional herbal medicine is used extensively among the Korean populations, and other Asian countries employ similar therapies as well In recent years, extensive focus was laid on adulteration of the herbal medicine with heavy metals. This may be mainly due to a soil contamination by an environmental pollution. The objective of this study is to identify the contents of various heavy metals in the blood from OhJeokSan-Decoction (OD) treated-rats. For this study, 13 kinds of metals including essential and heavy metals, i.e. Al, As, Cd, Co, Cr, Cu, Fe, Hg, Mn, Ni, Pb, Se and Zn were analyzed by a slight modification of EPA methods and the following results are obtained. ; 1. There is no significant difference between the OD-treated groups and control group in liver, kidney, bone, brain, weight, food intake. 2. The amount of each metal analyzed in the liver are as follows; Al ; $0.235{\sim}4.215mg／kg$, As ; $0.103{\sim}0.461mg／kg$, Cd ; $0.005{\sim}0.010mg／kg$, Co ; $0.017{\sim}0.046mg／kg$, Cr ; $0.137{\sim}0.403mg／kg$, Cu ; $1.736{\sim}4.827mg／kg$, Fe ; $54.472{\sim}381.447mg／kg$, Hg ; not detected, Mn ; $1.159{\sim}2.803mg／kg$, Ni ; $0.007{\sim}0.095mg／kg$, Pb ; not detected, Se ; $0.682{\sim}1.887mg／kg$, Zn ; $10.213{\sim}26.119mg／kg$, by groups, respectively. In control and other experimental group, several metal (Co, Cu, Mn, Zn, As, Cr) has a significant difference, but in experimental I and other experimental II, III, IV, V groups, there are no significant difference. 3. The amount of each metal analyzed in the kidney are as follows; Al ; $1.712{\sim}31.230mg／kg$, As ; $0.062{\sim}0.439mg／kg$, Cd ; $0.010{\sim}0.062mg／kg$, Co ; $0.000{\sim}0.101mg／kg$, Cr ; $0.125{\sim}0.636mg／kg$, Cu ; $3.385{\sim}12.502mg／kg$, Fe ; $41.148{\sim}99.709mg／kg$, Hg ; $0.000{\sim}0.270mg／kg$, Mn ; $0.433{\sim}2.301mg／kg$, Ni ; $0.000{\sim}0.221mg／kg$, Pb ; $0.000{\sim}0.584mg／kg$, Se ; $0.540{\sim}1.600mg／kg$, Zn ; $8.775{\sim}17.060mg／kg$, by groups, respectively. The concentration of Cu, Se, Cr, and Hg are variated significantly in control and other experimental group, and Cu, Se, Cd, Cr are variated significantly in experimental I and other experimental II, III, IV, V groups. 4. The amount of each metal analyzed in the bone(tibia and fibula) are as follows; Al ; $9.557{\sim}119.464mg／kg$, As ; $0.139{\sim}12.250mg／kg$, Cd ; $0.000{\sim}0.295mg／kg$, Co ; $0.022{\sim}0.243mg／kg$, Cr ; $0.239{\sim}1.999mg／kg$, Cu ; $0.000{\sim}2.291mg／kg$, Fe ; $240.249{\sim}841.956mg／kg$, Hg ; $0.000{\sim}0.983mg／kg$, Mn ; $0.214{\sim}7.353mg／kg$, Ni ; $5.473{\sim}11.453mg／kg$, Pb ; $0.000{\sim}8.502mg／kg$, Se ; $0.000{\sim}3.005mg／kg$, Zn ; $61.158{\sim}195.038mg／kg$, by groups, respectively. The concentration of Se, Cd are variated significantly in control and other experimental groups, and Se is variated significantly in experimental I and other experimental II, III, IV, V groups. 5. Exceptionally several metal concentration is increased or decreased. but there is no significant harmful difference of metal concentration in the liver, kidney and bone, from the OD-treated-rats compared to those of the control group even if higher dosage($1{\sim}8$ times dosage of person) of OD was administered. Thus, it is expected that the herbal decoction in the traditional herbal medicine would not lay any burden on the body and the heavy metal toxins would not affect our physiological system. However, other kinds of herbal treatment, such as i.v. and i.p. should be considered in terms of metal toxicity in the body since the level of certain metal.

• 대한한의학회지
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• 제23권1호
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• pp.67-82
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• 2002

Objectives: In recent years, extensive focus has been laid on adulteration of herbal medicine with heavy metals. This may be mainly due to soil contamination by environmental pollution. The objective of this study is to identify the contents of various heavy metals in the blood from Ohjeok-san (Wuji-san) Decoction (OD) treated-rats. Methods: For this study, 13 kinds of metals including essential and heavy metals, i.e. A1, As, Cd, Co, Cr, Cu, Fe, Hg, Mn, Ni, Pb, Se and Zn were analyzed by a slight modification of EP A methods and the following results are obtained. Results: 1. There was no significant difference between the OD-treated groups and control group in liver, kidney, bone, brain and weight, especially no significant difference at the 5th and 10th days in weight and the amount of food intake. 2. The amount of each metal analyzed in the blood were as follows; A1: 2.3~3.07 mg/l, As: 2.90~3.66 mg/l, Cd: 0~0.001 mg/l, Co: 0~0.01 mg/l, Cr: 0.40~043 mg/l, Cu: 0.93~1.88 mg/l, Fe: 414.35~464.46 mg/l, Hg: 0.01 mg/l, Mn: 0.10~0.17 mg/l, Ni: 0.01 mg/l, Pb: 0.03~012 mg/l, Se: 0.73 mg/l, Zn: 3.41~4.13 mg/l by groups, respectively. In control and experimental group, Experimental I and other experimental II, III, IV, and V groups, there were no significant differences. 3. The amount of non-toxic metals (A1, Co, Cu, Fe, Mn, Se, Zn) were $64.1{\pm}7.71{\;}mg/l$ in the control group and 60.70~67.58 mg/l in the experimental groups I, II, III, IV and V. The amount of Toxic metals (As, Cd, Cr, Ag, Pb) were $0.68{\pm}0.21{\;}mg/l$ in the control group and 0.57 ~ 0.66mg/l in the experimental groups. The total amount of metals were 32.35 mg/l in the control group and 30.48~34.12 mg/l in the test groups I, II, III, IV and V, respectively. Conclusions: There was no significant difference of metal concentration in the blood from the OD-treated-rats compared to those of the control group even if higher dosage (1~8 times the dosage for a person) of OD was administered. This may be mainly due to a decoction treatment which contains only supernatants filtered from the herb-mass after boiling. This indicates the legal limitation for metal concentration in herbal medicine must be applied according to different treatment methods of herbal medicine.

• 한국산업보건학회지
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• 제6권2호
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• pp.249-264
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• 1996

This study was conducted for the purpose of obtaining the fundamental data on improvement of working environment and contributing to health improvement of workers who dealed with metal by assessing the metal concentration in air of industries located in Chang-Won Industrial Complex. Authors measured the concentration of metals(Al, Cd, Cr, Cu, Mn, Ni, Pb, Sn and Zn) is the air to 25 working processes of 73 industries by flame atomic absorption spectrometry from February to December 1994. Personal air sampler was used for air sampling with mixed cellulose-ester membrane filter. The results were as follows : 1. The geometric means(range) of metal concentration; 1) Al: $0.1505mg/m^3$ ($0.0147-18.6100mg/m^3$) 2) Cd: $0.0077mg/m^3$ ($0.0003-7.0710mg/m^3$) 3) Cr: $0.0163mg/m^3$ ($0.0013-1.1510mg/m^3$) 4) Cu: $0.0097mg/m^3$ ($0.0009-0.4950mg/m^3$) 5) Mn: $0.0412mg/m^3$ ($0.0006-4.7877mg/m^3$) 6) Ni: $0.0088mg/m^3$ ($0.0001-1.0170mg/m^3$) 7) Pb: $0.0152mg/m^3$ ($0.0015-0.4499mg/m^3$) 8) Sn: $0.0486mg/m^3$ ($0.0037-0.1500mg/m^3$) 9) Zn: $0.1911mg/m^3$ ($0.0122-8.2920mg/m^3$) 2. The geometric mean of lead exceeded TWA in assembling process of other general purpose machinery not elsewhere classified products manufacturing industries.

• Journal of Microbiology and Biotechnology
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• 제7권3호
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• pp.167-173
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• 1997

Everted membrane vesicles of Helicobacter pylori were prepared and the membrane-resided ATPases were characterized. For comparison, Escherichia coli membrane ATPases and hog gastric mucosal H,K-ATPase were employed. ATPase assay revealed that the composite enzyme pool was relatively low in specific activities, below 1/10 times than that found in E. coli. According to their inhibitory specificities, most of the ATPase pool appeared to belong to the P-type ATPase, sensitive to vanadate but not to azide. The enzyme pool was extraordinarily resistant against treatment by N,N'-dicyclohexylcarbodiimide (DCCD). Certain monovalent cations, e.g., $K^+$ or $NH_4^{+}$ stimulated the whole enzyme pool only in the presence of $Mg^{2+}$. On the contrary, $Ni^{2+}$ and $Zn^{2+}$ increased enzyme activity rather effectively without the aid of $Mg^{2+}$. Under a defined condition employed, H. pylori cells could retain the membrane ATPase pool to the extent of $17{\%}$ at pH 3.2. Moreover, its activity was most stable in acidic conditions (pH 5.4-6.4). However, cytoplasmic or peripheral ATPase pools were hardly detected under acidity (below pH 4.6).

• 자원환경지질
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• 제36권4호
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• pp.295-304
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• 2003

옥천대의 흑색셰일 및 점판암이 존재하는 덕평-추부 지역의 암석-토양-작물계에서의 As의 부화정도, 분산양상, 환경지구화학적 관점에서 판단되는 잠재적 위해도의 평가를 위하여 암석, 토양 및 농작물시료를 채취하여 INAA, ICP-AES, ICP-MS를 이용하여 As을 포함한 잠재적 특성원소의 화학분석을 수행하였다. 암석분석의 결과 덕평 및 추부지역의 흑색셰일에서 As의 평균 함량은 각각 23 mg/kg, 57 mg/kg 로 전 세계 계일 및 흑색셰일의 평균값보다 부화된 값을 나타하였다. 이외에도 Ba, Cr, Mn, Mo, Ni, Se, U 및 V가 매우 부화된 양상을 보였다. 흑색셰일로부터 유래된 토양중의 As는 덕평지역의 밭토양은 28 mg/kg, 추부지역의 밭토양과 논토양은 33 mg/kg와 23 mg/kg로 농작물에 독성을 줄 수 있는 토양중의 잠재적 독성원소들의 최대 허용한계치(tolerable level) 보다도 부화된 값을 나타냈다. 토양시료들에 대한 As의 함량과 Mo, Se, U, Cu, Sb, Tl 간에는 비교적 좋은 양의 상관관계를 보였다 흑색 셰일 기반암 지역의 토양에서 재배된 농작물 시료에 대한 화학분석 결과, 벼의 줄기와 잎에 As의 축적이 매우 커서 덕평과 추부지역에서 각각 1.14 mg/kg와 1.35 mg/kg의 함량을 보인다. 토양내의 원소 함량과 작물 내로의 흡수정도인 생물학적 흡수계수(BAC, biological absorption coefficient)의 산출결과, As는 벼줄기와 잎>옥수수 잎>고추>콩잎=깻잎>옥수수 줄기>옥수수 열매의 순으로 감소하였으며, As가 열매와 같은 cereal products보다 잎과 식물에 토양으로부터 더 많은 양이 농축된다는 것을 추론학 수 있다.

• 환경위생공학
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• 제19권1호
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• pp.8-16
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• 2004

Ground water samples were collected from residential, green" industrial, landfill and mining area and analyzed for 23 inorganics from March to October in 2002. The results are as follows; 1. The detection frequencies of inorganic materials such as As, Ba, B, Mo, Ca, Mg, Al, Cu, Fe, Mn, Zn, Na, K were 7.2∼77.1% which showed that these inorganics were detected in many ground waters. 2. The detection frequencies of 7 inorganics(Cd, Cr, Ph, Se, Sb, Be, Tl) were commonly low at ranging from 0.42 to 2.5%. These inorganics were contained in ground water partially. 3. Three inorganics such as Hg, Ni, Ag were not detected in any ground-water samples. 4. Compared to the other areas, ground water samples from landfill area contained greater concentration in many inorgainics and then showed higher levels in industral, residential, mining and green area in order. 5. Compared to noted concentrations of bottled water, inorganic minerals including Ca, Mg, Na, K related to taste were fluent in target samples. The results showed that the average concentrations of Mg, Na, K were 4.0 mg/l, 14.7 mg/l, 1.5 mg/l respectively. 6. The concentrations of inorganics such as Sb, Ba, Mo, Be, Tl, K in some ground water samples exceeded the water quality standards of WHO, the US and UK. Especially, Ba, Mo, K also showed relatively high detection frequencies so these inorganics need to be considered as analytes in Korea Drinking Water Regulation in further study.

• 한국산업보건학회지
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• 제8권2호
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• pp.209-223
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• 1998

The aim of this study was to evaluate welders' exposure to hexavalent chromium (Cr(VI)) and nickel (Ni) during welding operations in a Korean shipyard. The airborne Cr(VI) and Ni concentrations were measured during metal inert gas (MIG) welding on mild and stainless steel, and manual metal arc (MMA) welding on mild steel. The geometric mean (GM) of Cr(VI) concentrations inside the welding helmet during MIG welding on mild steel were $0.0018mg/m^3$ inside a ship section, and $0.0015-0.0026mg/m^3$ at the welding shops. All of the personal breathing zone air samples were below the American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value ($TLV^{(R)}$) of $0.01mg/m^3$. Conversely, eighty-eight percent(21 of 24) of the personal breathing zone air samples exceeded the National Institute for Occupational Safety and Health (NIOSH) recommended exposure limit of $0.001mg/m^3$. Ni was not detected on 20 of 23 air samples collected during MIG welding on mild steel. The three Ni samples above the limit of detection ranged from 0.015 to $0.044mg/m^3$. The GM of Cr(VI) concentrations during MMA welding on mild steel were $0.0013mg/m^3$, but Ni was not detected in the air samples during this operation. It is assumed that the airborne Cr(VI) and Ni during mild steel welding were derived from the base metals which contained about 0.03% Cr and 0.03% Ni. The GM of airborne total Cr, Cr(VI) and Ni concentrations during MIG welding on stainless steel were 4.02, 0.13 and $0.86mg/m^3$, respectively, and the levels of Cr(VI) and Ni were above the ACGIH-$TLV^{(R)}$. Cr(VI) comprised about 35.5% of the total chromium(Cr) from MIG welding on mild steel, and about 8.4% of total Cr from MIG welding on stainless steel. The ratios of Cr(VI) to total Cr were significantly different among welding shops. It was concluded that welders were exposed to high levels of Cr(VI) and Ni during welding on stainless steel, and were exposed to low levels of Cr(VI) even during welding on mild steel.

• 한국환경보건학회지
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• 제27권4호
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• pp.63-71
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• 2001

PM 2.5/ samples were measured at two sites, Hadan(suburban site) and Anrak (roadside site) in Busan area. PM 2.5/ sampling was performed for 24-hour intervals by the FH9.5 particulate sampler. Aerosol samples were collected on PTFE filter. A total of 60 particulate samples were collected, dad samples were measured for Particulate mass concentration, metallic elements (Cr, Mn, Ni. Cu. Se, Fe, Pb, and Zn) and waer-soluble elements (C $l^{[-10]}$ , N $O_{3}$$^{[-10]}$ ,S $O_{4}$$^{2-}$, N $H_{4}$$^{+}$, $Ca_{2}$$^{+}$, $Mg_{2}$$^{+}$ and $^{+}$.Mass concentration in Hadan ranged 24.23~57.12 $\mu\textrm{g}$/㎥ and 60.22~72.12 $\mu\textrm{g}$/㎥m Yellow Sand Events. Major cations in Hadan and Anrak site is N $H_{4}$$^{+}$and N $a^{+}$ respectively. SO42$^{[-10]}$ was the abundant specie in the PM 2.5 fraction for Hadan site an dAnrak site. Hadan site showed igher concentration in S $O_{4}$$^{2.1}$ and N $H_{4}$ $^{+}$ In Anrak site the concentration of S $O_{4}$/sip 2-/and N $a^{+}$ was higher than other ions Prominent metallic elements were Fe and Pb in two sites. Principal component analysis showed that main source of PM 2.5 aerosol particles was non-metal related source which was resulted in relating elements as Cr, Ni, and Pb at Hadan site, Anrak site also has resulted PM2.5 aerosol paricles source, which was related its element like Zn, and Ni,. The SAS package analysis also showed that long-range transport effect at Hadan area due to Yellow Sand Event by the prevailing weaterlies.ling weaterlies.

• 한국초지조사료학회지
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• 제27권1호
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• pp.29-36
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• 2007

본 연구는 제주지역 목장 토양 및 조사료 자원의 미량광물질 함량을 평가하기 위해 수행되었다. 제주지역 98 목장에서 187 토양시료(농암갈색 76, 흑색 111) 및 말 농가에서 활용되고 있는 이탈리안라이그라스 건초, 혼합목초 건초, 수입 알팔파 건초 각 60시료를 채취해서 분석했다. 토양시료는 화학특성(pH, 유효인산, 치환성 양이온 함량)과 미량광물질(Cu, Fe, Cd, Zn, Mo, Se, Mn, Cr, Co, Ni) 총 함량 및 가용성 함량이 분석되었고, 조사료 시료는 미량광물질 총 함량이 분석되었다. 토양의 pH는 전체적으로 산성을 띄고 있었다(pH 5.1). 목장 토양 유효인산은 20.5 mg/kg, 치환성 Ca, Mg, K, Na은 각각 2.6, 0.9, 0.5, 0.2 cmol+/kg으로 낮게 나타나고 있다. 목장 토양 미량광물질 중 총 함량이나 가용성 함량 모두에서 검출되지 않은 원소는 없었다. 토양 미량광물질 총 함량에 비해 가용성 함량은 매우 낮은 수준을 나타냈다. 토양 미량광물질 중 Fe 총 함량이 가장 높고, Mn, Ni, Zn 총 함량도 다소 높게 나타났다. 부분적으로 토양 무기물 간 상관이 높았다. 조사료 자원에서 Cr은 검출되지 않았다. 기타 미량광물질 함량은 수입 알팔파 건초와 제주지역에서 생산된 건초 모두 일반적인 범위를 보여주었다. 그러나 제주지역에서 생산된 건초가 수입 알팔파 건초보다 Mn 함량(105 vs 23 mg/kg)은 높고 Mo 함량(2.7 vs 4.9 mg/kg)은 낮은 수준을 보였다. 본 연구결과 제주지역 목장 토양은 대부분 산성을 나타내고 양분 함량도 낮게 나타나고 있다. 제주지역 목장 토양 및 조사료에서 특정 미량광물질이 결핍되어 있는 것으로 보이지 않는다. 따라서 가축에게 미량광물질 첨가제의 보충급여는 사양형태나 사료 미량광물질의 함량 및 이용도 등을 고려하여 결정해야 할 것으로 사료된다.