• Title/Summary/Keyword: $LR_3$

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A Clinical Report of Systemic Lupus Erythematosus (전신성 홍반성 낭창(SLE) 환자 1례 증례보고)

  • Jeon, Yeong-Seon;Lee, Eun-Kyu;Kim, Soo-Hyeon;Choi, Yoo-Jin;Park, Kyeong-Mi;Yang, Seung-Jeong;Cho, Seong-Hee
    • The Journal of Korean Obstetrics and Gynecology
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    • v.31 no.4
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    • pp.179-187
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    • 2018
  • Objectives: The purpose of this study is to report the effect of Korean medicine treatments on a systemic lupus erythematosus (SLE). Methods: We treated 1 case of systemic lupus erythematosus patient with Korean herbal medicine, acupuncture, moxibustion and pharmaco-acupuncture. Patient is a 44-year-old woman, who suffered from general body weakness, arthralgia and foamy urine. She was treated with Samilshinki-hwan-gami and Oryeong-san-gami. Patient is taken acupuncture at GV20, CV12, LI4, LR3, ST36, BL23, BL25 and moxibustion at CV4. We injected pharmaco-acupuncture at BL23, BL25. Results: After treatments the patient recovered from foamy urine, reduced general body weakness, arthralgia. Conclusions: This study suggests that Korean medicine treatments have significant effect on reducing symptoms of systemic lupus erythematosus.

Trends of Korean Medicine Treatment for the Acute Stage of Herpes Zoster : A Review for the case reports (대상포진의 급성기 치료에 대한 국내 연구 현황 : 증례 보고 분석)

  • Kang, Min-Seo;Kim, Min-Hee;Choi, In-Hwa
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.33 no.1
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    • pp.56-74
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    • 2020
  • Objectives : The purpose of this study is to analyze the trend of Korean medical treatments on acute stage of herpes zoster. Methods : Domestic databases(OASIS, KTKP, RISS, NDSL, KISS) were used to search case study papers related to the acute herpes zoster. Total 33 studies were selected and analyzed. Results : According to clinical type, Ramsay Hunt syndrome was the most frequent type, followed by herpes zoster genralisatus, facial herpes zoster. Manual acupuncture was the most frequently used treatment modalities, followed by Korean herbal medicine. LI4(合谷), LR3(太衝), ST36(足三里), GB20(風池) were the major acupoints used for the treatment of acute herpes zoster. Yongdamsagan-tang(龍膽瀉肝湯) was the most frequently used prescription followed by Ligigeopoong-san(理氣祛風散). As principal herb, Gentianae Scabrae Radix et Rhizoma(龍膽) and Bupleuri Radix(柴胡) were the most frequently used herbs followed by Alismatis Rhizoma(澤瀉). Conclusions : Though several limits remains, this is the first study to analyze the trends of Korean medicine treatment for the acute stage of herpes zoster, it may helpful for the clinical practitioner.

Study on Optimal Welding Condition for Shipbuilding Steel Materials (조선강재의 최적 용접조건에 관한 연구)

  • Kim, Ok-Hwan
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.10 no.6
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    • pp.128-133
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    • 2011
  • In this study, the steel material for shipbuilding(LR-A class) was used, and FCAW was taken advantage of 3G attitude and they are welded by different welding ways. As a result of analyzing wave with welding monitoring system, the stable values are obtained which are the first floor(electronic current 164~182 A, voltage 24 V), the second floor(electronic current 174~190 A, voltage 22~25 V), the third floor(electronic current 158~188 A, voltage 22~25 V), and fourth floor(electronic current 172~184 A, voltage 22~25 V), at this time, the stable wave standard deviation and changing coefficient could be obtained. When the welding testing through nondestructive inspection was analyzed know defect of welding, there was no defect of welding in A, D, E, but some porosities in B, and slag conclusion near the surface in C, because the length of arc was not accurate, and the electronic current and voltage was not stable. After observing the change of heat affect zone through micro testing, each organization of floor formed as Grain Refinement, so welding part was fine, the distance of heat affect zone is getting wider up to change the values of the electronic current and voltage. As a result of degree of hardness testing, the hardness orders were the heat affect zone(HAZ), Welding Zone(WZ), and Base Metal(BM). When the distribution of degree of hardness is observed. B is the highest degree of hardness The reason why heat effect zone is higher than welding zone and base metal, welding zone is boiled over melting point($1539^{\circ}C$) and it starts to melt after the result of analysis through metal microscope, so we can know that delicate tissue is created at the welding zone. Therefore, in order to get the optimal conditions of the welding, the proper current of the welding and voltage is needed. Furthermore the precise work of welding is required.

SLA Homozygous Korean Native Pigs and Their Inbreeding Status Deduced from the Microsatellite Marker Analysis

  • Jung, Woo-Young;Lim, Hyun-Tae;Lim, Jae-Sam;Kim, Sung-Bok;Jeon, Jin-Tae;Lee, Jun-Heon
    • Journal of Animal Science and Technology
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    • v.52 no.6
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    • pp.451-457
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    • 2010
  • The porcine MHC (Major Histocompatibility Complex), encoding the SLA (Swine Leukocyte Antigen) genes, is one of the most significant regions associated with immune rejection in relation to transplantation. In this study, three SLA class I (SLA-1, SLA-3, SLA-2) loci and three SLA class II (DRB1, DQB1, DQA) loci were investigated in the previously unidentified Korean native pig (KNP) population that was closely inbred in the Livestock Technology Research Station in Cheongyang, Korea. Total thirteen KNPs from four generations were genotyped for the SLA alleles and haplotypes were investigated using PCR-SSP (Sequence-Specific Primer) method. The results showed that all of these KNPs had Lr-56.30/56.30 homozygous haplotype, indicating high level of inbreeding in the SLA genes. The inbreeding status of these animals was also investigated using microsatellite (MS) markers. From the 50 MS markers investigated, 17 MS markers were fixed in all generations and the fixed alleles are increased as 26 loci for the fourth generation. Two MS markers, S0069 and SW173, were heterozygous for all the animals tested. Observed and expected heterozygosities were calculated and the average inbreeding coefficients for each generation were also calculated. In the fourth generation, the average inbreeding coefficients was 0.732 and this may increase with further inbreeding process. Analysis of the SLA haplotypes and MS alleles can give important information for breeding the pigs for xenotransplantation studies.

Localization of actin and myosin in Cryptosporidium parvum using immunogold staining (작은와포자충에서 면역황금염색법을 이용한 actin과 myosin의 위치 관찰)

  • 유재란;채종일
    • Parasites, Hosts and Diseases
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    • v.33 no.3
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    • pp.155-164
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    • 1995
  • The location of actin and myosin of the several stages of Cwptosporinium parvum was observed. The tissue antigen of C. pcruum was prepared through immunosuppression of IgG mice with Depomedrol . The thin sectioned specimens, which were incubated with the IgG fraction of the rabbit polyclonal antibodies raised against chicken back muscle actin and bovine uterus myosin, were treated with 10 nm gold-conjugated goat anti-rabbit IgG, Electrodense particles were located mainly on the pellicles of all observed developmental stages of the parasites. The number of actin gold particles in the cytoplasm increased when the parasite was dividing actively as in case of meronts. Especially in macrogametocytes, a lot of actin and myosin particles were synthesized and storaged as amilopectin-like bodies. There were many actin gold particles along the microspikes of cytoplasmic membranes in various developmental stages. The actin and myosin observed in this study may play important roles to control the shape of the parasites and movement of cytoplasmic membranes as cvtoskeletal proteins.

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Characteristics of Airborne Lidar Data and Ground Points Separation in Forested Area (산림지역에서의 항공 Lidar 자료의 특성 및 지면점 분리)

  • Yoon, Jong-Suk;Lee, Kyu-Sung;Shin, Jung-Il;Woo, Choong-Shik
    • Korean Journal of Remote Sensing
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    • v.22 no.6
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    • pp.533-542
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    • 2006
  • Lidar point clouds provide three dimensional information of terrain surface and have a great advantage to generate precise digital elevation model (DEM), particularly over forested area where some laser signals are transmitted to vegetation canopy and reflected from the bare ground. This study initially investigates the characteristics of lidar-derived height information as related to vertical structure of forest stands. Then, we propose a new filtering method to separate ground points from Lidar point clouds, which is a prerequisite process both to generate DEM surface and to extract biophysical information of forest stands. Laser points clouds over the forest stands in central Korea show that the vertical distribution of laser points greatly varies by the stand characteristics. Based on the characteristics, the proposed filtering method processes first and last returns simultaneously without setting any threshold value. The ground points separated by the proposed method are used to generate digital elevation model, furthermore, the result provides the possibilities to extract other biophysical characteristics of forest.

Pragmatic Combinations of Acupuncture Points for Lateral Epicondylalgia are Unreliable in the Physiotherapy Setting

  • Alvim, Danielle T.;Ferreira, Arthur S.
    • Journal of Acupuncture & Meridian Studies
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    • v.11 no.6
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    • pp.367-374
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    • 2018
  • This study describes the reliability of pragmatic combinations of acupuncture points for lateral epicondylalgia (LE) as prescribed by physiotherapists who were experts in acupuncture. Raters (n = 14; 33-59 years) independently prescribed acupuncture points for 30 simulated human patients with LE who were surveyed via a printed questionnaire. The frequency and cooccurrence of acupuncture points prescribed for patients with lateral epicondylitis were assessed. Absolute agreement and Light's kappa (${\kappa}_{Light}$) with 95% confidence interval (CI) were used to quantify the interrater agreement. Raters prescribed 103 unique acupuncture points in different combinations with a median (min-max) of 5 (0-11) acupuncture points. The most prescribed acupuncture point was LI-11 (297 of 420; 71%), and the most common cooccurring acupuncture points were LI-11 and LI-4 (160 of 420; 38%). The absolute agreement for prescribing the acupuncture points ranged from 70% (point GB-20) to 0% (points LI-10, SP-6, LI-11, GB-34, LI-12, and LI-4). Point LR-3 showed the highest interrater reliability for prescribing the acupuncture points [${\kappa}_{Light}=0.112$, 95% CI = (0.055-0.194)], whereas point LI-4 showed the lowest reliability [${\kappa}_{Light}=-0.003$, 95% CI = (-0.024 to 0.024)]. These findings suggest that pragmatic prescriptions of acupuncture points for LE are unreliable among physiotherapists who are experts in acupuncture. Explicit, high-level evidence-based rules for prescribing and teaching combinations of acupuncture points for LE are warranted.

A Review of Korean Medicine Treatment for Postherpetic Neuralgia

  • Kim, Min Ju;Cha, Hyun Ji;Lee, Young Rok;Kim, Beom Seok;Sung, Ki Jung;Choi, Hyeon Kyu;Lee, Ye Ji;Jeon, Ju Hyun;Kim, Young Il
    • Journal of Acupuncture Research
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    • v.38 no.4
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    • pp.245-256
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    • 2021
  • The purpose of this study was to analyze the Korean medicine treatment methods for Postherpetic Neuralgia (PHN) in Korea. There were 5 online databases searched (OASIS, NDSL, RISS, KISS and KMBASE) for studies which were related to PHN. A total of 12 studies were selected. Various treatments such as acupuncture, herbal medicine, and moxibustion were reported treatments for PHN, some of which included Western medicine and Korean medicine treatment. Korean herbal medicine was the most frequently used treatment method, followed by manual acupuncture. Sipjeondaebotanggami was the most frequently used prescription. Poria Sclerotium was the most frequently used principal herb, followed by Angelicae Gigantis Radix, Zingiberis Rhizoma, and Ginseng Radix. GB44, LI4, LR3 were the common acupoints used for the treatment of PHN. CV12 was the most frequently used moxibustion point, and gabapentin was the most frequently used concomitant Western drug. Additional research on Korean medicine treatment of PHN is expected in the future.

Effects and Safety of Electroacupuncture on Cold Hypersensitivity on Hands and Feet by Sasang Constitution: A Multi-center, Randomized Controlled Trial (수족냉증에 대한 전침치료의 사상체질별 효과 및 안전성: 다기관 무작위 대조군 연구)

  • Kwon, Na-Yoen;Yu, Jun-Sang;Kim, Dong-Il;Kim, Hyeong-Jun;Lee, Dong-Nyung
    • Journal of Sasang Constitutional Medicine
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    • v.33 no.2
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    • pp.47-64
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    • 2021
  • Objectives The purpose of this study was to figure out the effect and safety of electro-acupuncture and acupuncture on cold hypersensitivity on hands and feet(CHHF) by Sasang constitution. Methods 72 subjects were recruited from three Korean medical hospitals from October 2019 to October 2020. Subjects were randomly allocated in 1:1:1 ratio to electro-acupuncture group(EA group), acupuncture group(AC group), and control group. The EA and AC group received treatment twice a week for 5 weeks. We tried to confirm the effectiveness of electro-acupuncture and acupuncture treatment by checking changes in Visual analogue score(VAS), body temperature of LU4, PC8, ST32, LR3, and WHOQOL-BREF score. Results The VAS score of CHHF was reduced after treatment, and the effect continued for 4 weeks after the end of treatment in all Sasang constitution, all treatment groups. In all Sasang constitution, the body temperature of the electro-acupuncture group or acupuncture grouop was higher than that of the control group except LU4 in visit 11. And no clinically significant adverse events have been identified. Conclusions Electro-acupuncture and acupuncture treatment are effective on hypersensitivity on hands on feet, and the effect was shown regardless of Sasang constitution.

A Scoping Review of Acupuncture Points for Post-Stroke Sequelae: Focusing on the Electroacupuncture (뇌졸중 증상별 경혈 활용에 대한 주제범위 문헌고찰: 전침을 중심으로)

  • Lee, Hwa Yeon;Kim, Song-Yi;Choi, Su-Hyeon;Song, Ho Sueb
    • Korean Journal of Acupuncture
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    • v.38 no.4
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    • pp.197-208
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    • 2021
  • Objectives : The aim of this study was to conduct a scoping review focusing on acupuncture points information applied in experimental studies using electroacupuncture for stroke. Methods : First, we set the research question of this study to identify which acupuncture points were studied for various symptoms of post-stroke sequelae in clinical and animal experiments. For this purpose, among the records searched through EMBASE, experimental studies including acupuncture points used in electroacupuncture treatment for stroke were selected as inclusion criteria for this study. The acupoints information used in each experiment was extracted from the included studies according to the type of study design and symptoms of stroke sequelae, and quantitative analysis was performed. Results : A total of 973 studies using acupuncture treatment, of which 429 papers including electroacupuncture were analyzed. Most of the animal experiments were conducted on general conditions instead of specific symptoms of stroke, and in clinical studies, electroacupuncture studies were conducted on symptoms such as hemiplegia and spasticity, cognitive and mental problems, dysphagia, shoulder problems, and depression that occur after stroke. Acupuncture points such as GV20, ST36, LI11, and LI4 were mainly used regardless of stroke symptoms. Except for these acupuncture points, GV26, GV14, GV16, and GV24 were frequently used in animal experiments, and TE5, LI15, LI10, and LR3 were widely used in clinical studies. Conclusions : Although this study extracted and analyzed only the frequent acupuncture points in the electroacupuncture study for stroke. However, in the future, it is necessary to be able to secure the evidence for acupuncture treatment elements through comparative studies between different acupuncture points or other elements constituting electroacupuncture.