• Title/Summary/Keyword: $K^+$ currents

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Effect of Multiple Lightning Impulse Currents on Zinc Oxide Arrester Blocks (산화아연 피뢰기 소자의 다중 뇌 임펄스 특성)

  • Lee, Bok-Hee;Kang, Sung-Man;Pak, Keon-Young;Choi, Hwee-Sung
    • Proceedings of the KIEE Conference
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    • 2003.10a
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    • pp.22-24
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    • 2003
  • In this work, in order to investigate the effect of multiple lightning impulse currents on zinc oxide arrester blocks. We have been designed and fabricated a multi-impulse generator which can produce quintuple voltages with $1.2/50{\mu}s$ to 100kV and quintuple currents with $8/20{\mu}s$ to 12kA and we have evaluated the characteristics of zinc oxide arrester block using several electrical and physical methods after the multi-impulse test. It was found that the multi-impulse failures of ZnO arrester blocks were mainly caused by surface flashover and the multi-impulse currents test would be more suitable than single impulse current test in evaluation of the characteristics of zinc oxide arrester blocks corresponding to actual situations.

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Three-dimensional numerical modeling of sediment-induced density currents in a sedimentation basin (3차원 수치모의를 통한 침사지에서의 부유사 밀도류 해석)

  • An, Sang Do;Kim, Gi-Ho;Park, Won Cheol
    • Journal of Korean Society of Water and Wastewater
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    • v.27 no.3
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    • pp.383-394
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    • 2013
  • A sedimentation basin is used to remove suspended sediments which can cause abrasive and erosive wear on hydraulic turbines of hydropower plants. This sediment erosion not only decreases efficiency of the turbine but also increases maintenance costs. In this study, the three-dimensional numerical simulations were carried out on the overseas hydropower project. The simulations of flow and suspended sediment concentration were obtained using FLOW-3D computational fluid dynamics code. The simulations provide removal efficiency of a sedimentation basin based on particle sizes. The influence of baffles on the flow field and the removal efficiency of suspended sediments in the sedimentation basin has been investigated. This paper also provides the numerical simulations for sediment-induced density currents that may occur in the sedimentation basin. The simulation results indicate that the formation of density currents decreases the removal efficiency. When a baffle is installed in the sedimentation basin, the baffle provides intensive settling zones resulting in increasing the sediments settling. Thus the enhanced removal efficiency can be achieved by installing the baffle inside the sedimentation basin.

Stationary Outward and Transient $Ca^{2+}-Dependent$ Currents in Hamster Oocytes

  • Kim, Yang-Mi;Han, Jae-Hee;Kim, Jong-Su;Hong, Seong-Geun
    • The Korean Journal of Physiology and Pharmacology
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    • v.4 no.5
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    • pp.403-408
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    • 2000
  • The outward currents elicited in hamster eggs by depolarizing pulses were studied. The currents appeared to comprise at least two components, a transient outward component $(I_{to})$ and a steady-state outward component $(I_{\infty}).\;I_{to}$ was transiently followed by the cessation of inward $Ca^{2+}$ current $(I_{Ca}),$ and its current-voltage (I-V) relation was a mirror image of that of $(I_{Ca}).$ Either blockade of $(I_{Ca})$ by $Co^{2+}$ or replacement of $Ca^{2+}$ with $Sr^{2+}$ abolished $I_{to}$ without change in $I_{\infty}.$ Intracellular EGTA (10 mM) inhibited $I_{to}$ but not $I_{\infty}.$ suggesting strongly that generation of $I_{to}$ requires intracellular $Ca^{2+}.$ Apamin (1 nM) abolished selectively $I_{to},$ indicatingthat $I_{to}$ is $Ca^{2+}-dependent\;K^+$ current. On the other hand, $I_{\infty}$ was $Ca^{2+}-independent.$ Both $I_{to}$ and $I_{\infty}$ were completely inhibited by internal $Cs^+$ and external TEA. The estimated reversal potential of $I_{to}$ was close to the theoretical $E_K.$ Taken together, both outward currents were carried by $K^+$ channels. From these results, $I_{to}$ is likely to be a current responsible for the hyperpolarizing responses seen in hamster eggs at fertilization.

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4-Aminopyridine Inhibits the Large-conductance $Ca^{2+}-activated$ $K^+$ Channel $(BK_{Ca})$ Currents in Rabbit Pulmonary Arterial Smooth Muscle Cells

  • Bae, Young-Min;Kim, Ae-Ran;Kim, Bo-Kyung;Cho, Sung-Il;Kim, Jung-Hwan;Earm, Yung-E
    • The Korean Journal of Physiology and Pharmacology
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    • v.7 no.1
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    • pp.25-28
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    • 2003
  • Ion channel inhibitors are widely used for pharmacological discrimination between the different channel types as well as for determination of their functional role. In the present study, we tested the hypothesis that 4-aminopyridine (4-AP) could affect the large conductance $Ca^{2+}$-activated $K^+$ channel ($BK_{Ca}$) currents using perforated-patch or cell-attached configuration of patch-clamp technique in the rabbit pulmonary arterial smooth muscle. Application of 4-AP reversibly inhibited the spontaneous transient outward currents (STOCs). The reversal potential and the sensitivity to charybdotoxin indicated that the STOCs were due to the activation of $BK_{Ca}$. The $BK_{Ca}$ currents were recorded in single channel resolution under the cell-attached mode of patch-clamp technique for minimal perturbation of intracellular environment. Application of 4-AP also inhibited the single $BK_{Ca}$ currents reversibly and dose-dependently. The membrane potential of rabbit pulmonary arterial smooth muscle cells showed spontaneous transient hyperpolarizations (STHPs), presumably due to the STOC activities, which was also inhibited by 4-AP. These results suggest that 4-AP can inhibit $BK_{Ca}$ currentsin the intact rabbit vascular smooth muscle. The use of 4-AP as a selective voltage-dependent $K^+$ (KV) channel blocker in vascular smooth muscle, therefore, must be reevaluated.

Ginseng Saponins Enhance Maxi $Ca^{2+}-activated\;K^+$ Currents of the Rabbit Coronary Artery Smooth Muscle Cells

  • Chunl Induk;Kim Nak-Doo
    • Journal of Ginseng Research
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    • v.23 no.4
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    • pp.230-234
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    • 1999
  • Potassium channels play an important role in regulating vascular smooth muscle tone. Four types of $K^+$ channels areknown to be expressed in vascular smooth muscle cells, and maxi $Ca^{2+}-activated\;K^+$ channel $(BK_{Ca})$ is a dominant type of $K^+$ channels in these cells. Because total ginseng saponins and ginsenoside $Rg_3$ cause vasodilation with unclear mechanisms, we hypothesized that total ginseng saponins and ginsenoside $Rg_3$ induce vasodilation via activation of maxi $Ca^{2+}-activated\;K+$ channels. Whole-cell BKe. currents were voltage-dependent with half maximum activation at -14 mV, and the currents were sensitive to nanomolar ChTX and millimolar TEA. External application of total ginseng saponins increased the anlplitude of the whole-cell BKe. current in a concentration-dependent manner. Single-channel analysis indicates that total ginseng saponins caused the channel opening for a longer period of time. Ginsenoside $Rg_3$ increased the amplitude of whole-cell $K_{Ca}$ currents without affecting voltage dependence of the currents and increased single-channel open time. Hence, the results suggest that ginseng saponin-induced vasodilation may be due to activation of $K_{Ca}$.

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Field Observations of Wave-Induced Currents at Bonggil Beach (동해 봉길해안에서 해빈류의 현지 관측)

  • LEE YOUNG KWEON;YANG HAE YANG;PARK IL HEUM;LEE JONG SUP;KIM JONG KYU
    • Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
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    • 2004.05a
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    • pp.145-150
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    • 2004
  • Using the DGPS of high precision take in a bouy, the wave-induced currents were observed by Lagrange method at Bonggile beach of the East Sea. At June, the northward wave-induced currents were dominated by the SSW waves. And the southward flaws were appeared at September and November. When 0.2-0.4m wave heights attacked the beach, the mean speed of the wave-induced currents was 0.15-0.3m/s at June and September, when the 1.0-1.6m wave heights incidented at November, that was about 0.3-0.6m/s. On the other hand, the observed results were compared with the simulated results which were solved by the 2-D model, WICU-DIVAST. It was showed the reasonable agreements.

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Analysis of Magnetization Currents

  • Miteva, Neda;Slonim, Michael
    • Journal of Electrical Engineering and Technology
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    • v.11 no.6
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    • pp.1610-1613
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    • 2016
  • An analytical method for harmonic estimation of magnetization currents has been developed. The method is based on the results of the waveforms qualitative analysis. The calculation and the experimental results are compared. A good matching is observed.

Characteristics of Tidal Current and Tidal Residual Current in the Archipelago Around Aphae Island in the Southwestern Waters of Korea (한국 서남해 압해도 주변 다도해역의 조류 및 조석잔차류 분포)

  • Choo, Hyo-Sang;Kim, Dong-Sun
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.24 no.2
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    • pp.179-187
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    • 2018
  • In order to understand the flow of currents around Aphae Island and the surrounding Archipelago, the numerical model experiments on tidal currents and tide-induced residual currents were carried out. Dominant semidiurnal tidal currents have a reversing form and flow along the narrow channels of the archipelago. During periods of flood, currents flow from the west of Hwawon Peninsula to the archipelago to the northwest together with the currents flowing from the channels at Palgeum Island to Amtae Island and Amtae Island to Jeung Island. Ebb currents flow from the northwest archipelago to the channel of Amtae Island and Jeung Island as well as Amtae Island to Palgeum Island, further flowing south between Palgeum Island and Hwawon Peninsula. Flood currents are separated from east and west at the southern coast of Aphae Island, but flow south from both the west and east of Aphae Island to the channel found between Palgeum Island and Hwawon Peninsula at ebb. Flow speed is high between Amtae Island and Aphae Island where the flows meet and join. Lee wakes or topographical eddies are formed around the islands due to the high speed of the currents flowing along the narrow channel in the archipelago, manifesting as a tide-induced residual current. A weak cyclonic wake and anti-cyclonic eddy both exist at the west and northwestern coast of Aphae Island individually. The speed of the tide-induced residual current become slow on account of the wide littoral zone at exists around Aphae Island.

Characterization of Voltage-Gated Potassium Currents in Dorsal Root Ganglion Neurons of Neonatal Rats (신생흰쥐 척수후근신경절 세포에서 전압의존성 $K^+$ 전류의 동정)

  • Kim, Ji-Mok;Jung, Sung-Jun;Kim, Sang-Jeong;Kim, Jun
    • The Korean Journal of Physiology and Pharmacology
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    • v.1 no.6
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    • pp.613-624
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    • 1997
  • Dorsal root ganglion (DRG) is composed of neuronal cell bodies of primary afferents with diverse functions. Various types of ion channels present on DRG neurons may reflect those functions. In the present study, voltage-gated potassium currents in DRG neurons of neonatal rats were characterized by whole-cell voltage clamp method. Two types of delayed rectifier and three types of transient potassium currents were identified according to their electrophysiological properties. The delayed rectifier currents were named $I_{Ke}$ (early inactivating) and $I_{K1}$ (late inactivating). Steady state inactivation of $I_{Ke}$ began from -100 mV lasting until -20 mV. $I_{K1}$ could be distinguished from $I_{Ke}$ by its inactivation voltage range, from -70 mV to +10 mV. Three transient currents were named $I_{Af}$ (fast inactivation), $I_{Ai}$ (intermediate inactivation kinetics), and $I_{As}$ (slow inactivation). $I_{Af}$ showed fast inactivation with time constant of $10.6{\pm}2.0$ msec, $I_{Ai}$ of $36.9{\pm}13.9$ msec, and $I_{As}$ of $60.6{\pm}2.9$ msec at +30 mV, respectively. They also had distinct steady state inactivation range of each. Each cell expressed diverse combination of potassium currents. The cells most frequently observed were those which expressed both $I_{K1}$ and $I_{Af}$, and they had large diameters. The cells expressing $I_{Ke}$ and expressing $I_{Ke}$, $I_{Ai}$, and $I_{As}$ usually had small diameters. Judging from cell diameter, capsaicin sensitivity or action potential duration, candidates for nociceptor were the cells expressing $I_{Ke}$, expressing $I_{Ke}$ and $I_{Ai}$, and expressing $I_{Ke}$ and $I_{As}$. The types and distribution of potassium currents in neonatal rat DRG were similar to those of adult rat DRG (Gold et al, 1996b).

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Numerical Simulations of Cellular Secondary Currents in Open-Channel Flows using Non-linear k-ε Model (비선형 k-ε 모형을 이용한 개수로 흐름에서의 격자형 이차흐름 구조 수치모의)

  • Kang, Hyeongsik;Choi, Sung-Uk;Park, Moonhyeong
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.28 no.6B
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    • pp.643-651
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    • 2008
  • In the present paper, turbulent open-channel flows over longitudinal bedforms are numerically simulated. The Reynolds- averaged Navier-Stokes equations in curvilinear coordinates are solved with the non-linear $k-{\varepsilon}$ model by Speziale( 1987). First, the developed model is applied to rectangular open channel flows for purposes of model validation and parameter sensitivity studies. It is found that the parameters $C_D$ and $C_E$ are important to the intensity of secondary currents and the level of turbulent anisotropy, respectively. It is found that the non-linear $k-{\varepsilon}$ model can hardly reproduce the turbulence anisotropy near the free surface. However, the overall pattern of the secondary currents by the present model is seen to coincide with measured data. Then, numerical simulations of turbulent flows over longitudinal bedforms are performed, and the simulated results are compared with the experimental data in the literature. The simulated secondary currents clearly show upflows and downflows over the ridges and troughs, respectively. The numerical results of secondary currents, streamwise mean velocity, and turbulence structures compare favorably with the measured data. However, it is observed that the secondary currents towards the troughs were significantly weak compared with the measured data.