• Microbiology and Biotechnology Letters
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• v.37 no.3
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• pp.273-279
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• 2009

Hyungbangjihwang-Tang (HT), an Oriental herbal formula, has been known to play a role which helps to recover vigor of human in the Orient. In this study, antifungal substance (HTI) was purified from the ethyl-acetate extracts of HT by using $SiO_2$ column chromatography and HPLC, and the antifungal effects of HTI and its mode of action were investigated. By using a broth micro-dilution assay, the activity of HTI was evaluated against fungi. HTI showed antifungal activities without hemolytic effect against human erythrocytes. To confirm antifungal activity of HTI, we examined the accumulation of intracellular trehalose as stress response on toxic agents and effect on dimorphic transition in Candida albicans. The results demonstrated that HTI induced the accumulation of intracellular trehalose and exerted its antifungal effect by disrupting the mycelial forms. To understand its antifungal mode of action, cell cycle analysis was performed with C. albicans, and the results showed HTI arrested the cell cycle at the S phase in yeast. The present study indicates that HTI has considerable antifungal activity, deserving further investigation for clinical applications.

• Journal of Korean Library and Information Science Society
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• v.31 no.2
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• pp.253-278
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• 2000

Th~ss tud is to recommend a suggestion to adapt and expand the class 200 Religon for Korean libraries using DDC. The grst art of it investigates the development and general problem of the options in 200 and leads to the conclusion t k t it is somewhat undesirable to use the options in the libraries of the nations m y religions are predominant, as in Korea. The second part of it recommends a su gestion. The major characteristic of it is that it not onl follows the basic systems and order of the DDC but a k suggests the plan that emphasizes the Budhsm andother religions of brea, Ouna, and Japan, for Korean libraries. It contracts the Christianity of 22@280 in oripl DDC lnto only one division 220, and rearran es the divisions 230-270 for the BudNusm and other religions oi the world so that various religons can be inc\ulcorneruded in the divisions. And it also su ests an alternative for the libraries that want to ernphaslzc the Buddhism and other religions of East-Asian anp~orean o r i p .

• Korean journal of applied entomology
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• v.19 no.1 s.42
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• pp.51-55
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• 1980

The study has been carried to confirm pathogenesity among the isolates which obtained from leaf blight type symptoms and Kresek type symptoms, and also to observe varietal resistance among 29 varieties and/or lines through the introduction of two different pathotypes, of Xanthomonas oryzae, by the use of root clipping and pin prick methods. There was no significant differences among the isolates when their growth in plant tissue were compared. There was certain tendency, however, that the isolates from Kreseked plants showed longer lesion than those from blight type lesions. Both isolates from blight type and Kresek type induced the same degree of Kresek syptoms when they were introduced into plants by root cutting in the suspension prior to transplant. Varietal resistance to 'Kresek' appeared to be the same with those on leaf blight type though Wase Aikoku group varieties showed Kresek symptoms which is not the case with leaf blight type. IR 20 in Kogyoku group varieties showed highly resistant reaction to Kresek type. Root clipping method induced the more of Kresek than those by pin pricking method.

• 한국생물공학회:학술대회논문집
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• 2005.10a
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• pp.651-654
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• 2005

Analysis of extra- and intra- cellular metabolites is very important to study cell metabolish. Intracellular amino acids in yeast are of great interest as precursors of desired products in biomass production of the feed industries and the production of glutamate. In this study, the fermentations of P. pastoris X-33 and KM71H were carried out in shake flasks. After centrifugation, the harvested cells were mechanically disrupted by using glass bead. The supernatants were used to analyze intracellular amino acid by HPLC system. For HPLC analysis, Resolve C18 column was used with Fluorescence detector. The OPA(o-phthalaldehyde) derivation reaction was employed for analysing amino acids at 30 $^{\circ}C$, 1 ml/min and gradient mode. The concentration of intracellular protein was measured by spectrophotometer.

• Journal of the Korea Fashion and Costume Design Association
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• v.7 no.1
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• pp.85-99
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• 2005

This study is to know the blue jean image according to type and its constituting element. and also to analyze image according to the sex of wearers and recognizers, the existence and nonexistence of blue jean affect the wearer's body type. Thirty-six photo stimulus material attached to men and women wearers selected as people of skinny types, average types and fat types, were seen to 1,354 men and women university students and had them measure blue jean image and element of twenty one items. 1, The blue jean image was different according to design type. The broad blue jean was active but it looked fat. The bleached blue jean matched with any clothing. The legs looked long. Painting blue jean seemed o be new, colorful, splendid, The torn blue jean appeared to match with any clothing. And lap seam blue jean was active but the waist seemed as thick image. 2, In the wearer's body type, the jeans image strengthen the wearer's body image. The legs looked long. The fat type appeared high in the item like this; they looked fat. The waist looked thick. It was courageous and casual. It appeared that the fat element appeared as blue jean image of fat type. 3, In the relation of wearer's sex and blue jean image, when the wearers were men, the image was passable. It matched with anyone. It was splendid and refined. The legs appeared long. When the wearers were women, the blue jean image was economic. It had no relation with a fashion. It was active, comfortable, free, casual and fat. The waist looked thick. In image element, activity and fat element appeared as a main element of the blue jean image.

• Korean journal of applied entomology
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• v.23 no.4 s.61
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• pp.242-246
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• 1984

Results obtained from the experiment conducted to find out e relationships between tuber decay, and water potential and bruising in or on the tubers, are summerized as follows ; 1) When potato tubers were bruised or injected with bacterial inoculum, the tubers with high water potential rotted more easily than the tubers with low potential. A big difference in the development of decay between high and low water potential tubers was found. 2) In tubers injected with different levels of inoculum. high water potential tubers were more susceptible to soft rot than low water potential tubers. 3) $ED_{50}$ of inoculum concentration was 8.5(log) at high water potential tubers and 9.8(log) at low water potential. A small difference between low and high water potential was detected. The results of this experiment show that potatoes should be handled carefully and must be dried after harvest to reduce decay development in shipment and storage.

• Journal of The Korean Astronomical Society
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• v.41 no.5
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• pp.121-137
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• 2008

We present optical and near-infrared imaging and long-slit spectroscopy for the blue compact dwarf galaxy (BCD) Mrk 49 in the Virgo Cluster. The surface brightness distribution analysis shows that Mrk 49 consists of an off-centered blue bright compact core of r = 10" and a red faint outer exponential envelope. The $H_{\alpha}$ image and color difference suggest that these two components have different stellar populations: a high surface brightness population of massive young stars and an underlying low surface brightness population of older stars. The redder near-infrared colors of the inner most region suggest that the near-infrared flux of Mrk 49 originates from evolved massive stars associated with the current star-forming activity. The total apparent magnitude is $B_T\;=\;14.32$ mag and the mean effective surface brightness is ${\mu}_{eff}(B)\;=\;21.56$ mag $arcsec^{-2}$. Long-slit spectroscopy shows that Mrk 49 rotates apparently as a solid body within r = 10" in a plane at position angle 55 degrees with an amplitude of about $20\;km\;sec^{-1}$. The measured radial velocity of Mrk 49 was derived as $1,535\;km\;sec^{-1}$; and the total mass of stars and gases is in the range of 3 to $6\;{\times}\;10^9\;M_{\odot}$. The mass-to-light ratios for the central region of Mrk 49 in I and B band are estimated 1.0 and 0.5, respectively. The upper limit of the dark matter to visible matter ratio seems to be < 5. The oxygen abundance is $12\;+\;\log(O/H)\;=\;8.21\;{\pm}\; 0.1$ which is about one quarter of the solar value while the relative helium abundance appears to be similar to that of the sun.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.9
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• pp.5311-5316
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• 2013

A functional polymorphism in the NQO1 gene, featuring a 609C>T substitution,leading to proline to serine amino-acid and enzyme activity changes, has been implicated in cancer risk. However, individually published investigations showed inconclusive results, especially for leukemia. In this study, we therefore performed a meta-analysis of 21 publications with a total of 3,634 cases and 4,827controls, mainly for leukemia. We summarized the data on the association between the NQO1 609C>T polymorphism and risk of leukemia and performed subgroup analyses by ethnicity and leukemia type. We found that the variant TT homozygous genotype o was associated with a modestly increased risk of leukemia (TT versus CT/CC: OR=1.23, 95%CI=1.00-1.51, heterogeneity=0.76; $I^2$=0%). Following further stratified analyses, increased risk was only observed in subgroups of Caucasians. This meta-analysis suggests that the NQO1 609T allele is a high-penetrance risk factor for leukemia in Caucasians. The effect on leukemia may be modified by ethnicity and leukemia type, and the small sample sizes of the subgroup analyses suggest that further larger studies are needed.

• Journal of ILASS-Korea
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• v.20 no.1
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• pp.28-34
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• 2015

Recently, some researchers have been carried out risk assessment of vehicles exhaust on human health. Especially, some of VOCs which is non-controlled, was classified to hazardous pollutant, such as 1,3-Butadiene and BTEX(Benzene, Toluene, Ethylbenzene and Xylene). Therefore, the profile on non-controlled pollutant may be needed in the future, because it would be critical data or information to control them. Additionally, with increasing amount of motorcycle, the source profiling is essential for estimating emission factor and amount on motorcycle exhaust. For these, in this study, imported motorcycles (8 vehicles) were selected as a test model while considering the increasing ratio on sales volume between 2013 and 2014; it was also compared with domestic motorcycles on those. The experiment was conducted by driving mode, UDC and ECE+EUDC that made from EURO III. In addition, it was performed at cold start driving mode without effect by displacement, for evaluating only correlation of BTEX with HC. In order to apply the ratio (m,p-Xylene/o-Xylene) as a marker, the ratio was compared with those of tunnel, road side and residential area. As a result, it showed best correlation ($R^2=0.98$) among those. In the future, it has to be considered as a marker for effect evaluation to atmospheric environment by exhaust emission.

• Journal of Oriental Neuropsychiatry
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• v.24 no.4
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• pp.363-372
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• 2013

Objectives: The purpose of this study is to investigate the usefulness of psychological measurements in depression symptoms as compared with non-depressions and hwabyung. Methods: A total of 21 patients, who were diagnosed with depression and hwabyung, were evaluated by using the SCL-90-R, BDI, STAI, STAXI, ISI, HRSD, 20-Item Alexithymia Scale, BSDS and NEO-PI. Thereafter, they were statistically analyzed. Results: 1) In the results of SCL-90-R, the PST score group of hwa-byung group without depression was significantly higher when compared to the score from the depression group without hwa-byung. 2) In the results of NEO-PI, the NEO-PI-O score of hwa-byung group without depression was significantly higher when compared to the score from the depression group without hwa-byung. 3) In the results of 20-Item Alexithymia Scale, the total score and score of difficulty for identifying feelings scale from the depression group was significantly higher when compared to the score of non depression group. Conclusions: The results found are expected to serve as a useful resource for future studies when developing the instruments of oriental medical evaluations for hwa-byung.