• Steel and Composite Structures
• /
• 제39권3호
• /
• pp.319-335
• /
• 2021

This study proposes a new and highly-accurate artificial intelligence model, namely ANN-IP, which combines an interior-point (IP) algorithm and artificial neural network (ANN), to improve the axial compression capacity prediction of elliptical concrete-filled steel tubular (CFST) columns. For this purpose, 145 tests of elliptical CFST columns extracted from the literature are used to develop the ANN-IP model. In this regard, axial compression capacity is considered as a function of the column length, the major axis diameter, the minor axis diameter, the thickness of the steel tube, the yield strength of the steel tube, and the compressive strength of concrete. The performance of the ANN-IP model is compared with the ANN-LM model, which uses the robust Levenberg-Marquardt (LM) algorithm to train the ANN model. The comparative results show that the ANN-IP model obtains more magnificent precision (R² = 0.983, RMSE = 59.963 kN, a20 - index = 0.979) than the ANN-LM model (R² = 0.938, RMSE = 116.634 kN, a20 - index = 0.890). Finally, a new Graphical User Interface (GUI) tool is developed to use the ANN-IP model for the practical design. In conclusion, this study reveals that the proposed ANN-IP model can properly predict the axial compression capacity of elliptical CFST columns and eliminate the need for conducting costly experiments to some extent.

• 한국수정란이식학회지
• /
• 제18권3호
• /
• pp.215-225
• /
• 2003

본 시험은 한우에서 연령에 따라 혈청성분들의 변화를 알아보기 위하여 한우 866두(거세 638, 비거세 228)에 대하여 혈청 농도를 분석하여 채혈시 일령을 독립 변량으로 하고 혈청 성분들을 종속변수로 하는 다항 회귀방정식으로 추정한 결과는 다음과 같다. 거세우나 비거세우 모두 같은 차수의 회귀방정식이 접합한 혈청 성분은 IGF- I (3차식) calium(1차식) 및 IP(1차식)이었고 거세우에서는 1차식이 적합하고 비거세우에서는 3차식이 적합한 혈청 성분은 testosterone와 creatinine었다. 반면에 HDLC는 거세우에서는 3차식이 적합하나 비거세우에서는 1차식이 적합한 것으로 나타났다. 그리고 거세우에서는 2차식이 적합한데 비거세우에서는 3차식이 적합한 혈청성분은 triglyceride 농도와 globulin농도 그리고 A/G비율 등이었고, 거세우에서는 3차식이 적합하고 비거세우에서는 2차식이 적합한 혈청성분은 BUN이었으며, 거세우에서는 2차식이 적합한데 비거세우에서는 1차식이 적합한 혈청성분은 TP와 albumin이었다. 한편 cortisol은 거세우나 비거세우에서 모두 3차식까지의 회귀방정식으로는 연령에 따른 변화를 설명하기가 적합하지 않았으며 glucose는 비거세우에서는 3차식 변화를 보이고 있으나 거세우에서는 3차식까지의 회귀방정식만으로는 연령에 따른 변화를 설명하기가 어려웠다. 가장 적합한 것으로 판단되는 혈청성분들의 회귀모형 중에서 비교적 R-SQUARE 값이 높은 것(R-SQUARE value>0.1)들은 거세우에서 ICF-I, albumin, creatinine, IP, HDLC 등이었으며, 비거세우에서 testosterone, IGF-I, TP, albumin, glucose, creatinine, IP, HDLC 등으로 나타났다. 따라서 IGF-I, albumin, creatinine, IP, HDLC 등은 거세우나 비거세우 모두에서 연령에 따라 비교적 큰 변화를 보이는 혈청 성분이라고 생각된다.

• 전력전자학회:학술대회논문집
• /
• 전력전자학회 2008년도 하계학술대회 논문집
• /
• pp.637-639
• /
• 2008

본 논문은 밀폐형 구조를 갖는 3.3kW급 태양광용 전력변환기 개발에 관한 내용을 설명한다. 3.3kW급 전력변환기는 무게, 부피, 효율적인 측면에서 장점을 갖는 무변압기형으로 동작범위가 넓고 실외형(IP65)으로 제작되어 설치 장소에 제약을 받지 않는다. 또한, 주변온도 $-20{\sim}50^{\circ}C$에서 동작이 가능하도록 설계 되었다.

• 대한의생명과학회지
• /
• 제13권4호
• /
• pp.333-339
• /
• 2007

Recently, much attention has been paid to human retinoblastoma since it provide a good model system for studying mechanisms underlying cell growth, differentiation, proliferation, and apoptosis, and for developing cancer therapy. However, until now it is unclear whether purinergic receptors are involved in the calcium mobilization in the retinoblastoma cells. In this regard, we measured possible purinergic signaling in WERI-Rb-1 cells using $Ca^{2+}$ imaging technique and RT-PCR method. ATP-induced $[Ca^{2+}]_i$ transients was maintained to about $90.7{\pm}1.0%$ of the control (n=48) even in the absence of extracellular calcium. The ATP-induced intracellular calcium response was only attained to $10.4{\pm}1.8%$ (n=55) of peak amplitude of the control after preincubation of 1 ${\mu}MU-73122$, a PLC inhibitor, but it was not affected by 1 ${\mu}MU-73343$, a inactive form of U-73122. And also ATP-induced $[Ca^{2+}]_i$ rise was almost attenuated by 20 ${\mu}M$ 2-APB, a putative $IP_3$ receptor inhibitor. Two subtypes of $IP_3$ receptor $(IP_{3-1}R,\;IP_{3-2}R)$ were identified by a RT-PCR method. These findings suggest that purinergic stimuli can cause calcium mobilization via $PLC-IP_3$ pathway after the activation of P2Y receptors in the retinoblastoma cells, which may play important roles in cell proliferation, differentiation, growth, and cell death.

• 한국우주과학회:학술대회논문집(한국우주과학회보)
• /
• 한국우주과학회 2010년도 한국우주과학회보 제19권1호
• /
• pp.39.1-39.1
• /
• 2010

We have investigated interplanetary (IP) structures of 82 intense geomagnetic storms (Dst $\leq$ -100 nT) that occurred from 1998 to 2006. According to their interplanetary origins, we classified them as four groups: 20 sMC events (IP shock and MC), 19 SH events (sheath field), 12 SH+MC events (Sheath field and MC), and 8 nonMC events (non-MC type ICME). For each group, we examined the relationships between Dst index and solar/IP parameters, namely, direction parameter (DP), CME speed ($V_{CME}$), solar wind speed ($V_{SW}$), minimum of IMF $B_z$ component($Bz_{min}$), and maximum of $E_y$ component ($Ey_{max}$).We found that the relationships strongly depend on their IP source. Our main results can be summarized as follows: 1) The correlation between Dst and DP is the best for the SH+MC events (r = -0.61). 2) The relationship between Dst and $V_{CME}$ gives the best correlation for the sMC events (r = -0.56). 3) There is the best correlation between Dst and $V_{SW}$ for the sMC events (r = -0.61), while there is a very weak correlation (r=-0.17) for the SH events. 4) The relationship between Dst and $Bz_{min}$ gives the best correlation (r = -0.87) for the SH+MC events. 5) The correlation between Dst and $Ey_{max}$ is the best for the SH+MC events (r = -0.87). Summing up, the sMC and SH+MC events give us good correlations, but the SH events, weak correlations. From this study, we suggest that this tendency should be caused by the characteristics of IMF southward components, e.g., smooth field rotations for the MC events and highly IMF fluctuations for the SH events.

• 생물환경조절학회지
• /
• 제29권3호
• /
• pp.245-251
• /
• 2020

본 시험은 저면관수 방식의 파프리카 육묘 시 암면큐브에 대한 다양한 급액시점 (IP 30%, 40% 50%, 60% 및 70%)에 따른 파프리카 묘의 소질을 조사하였다. 급액시점에 따른 파프리카 묘의 생육량은 급액시점과 정의상관을 나타내었다. 특히 IP 30~40% 처리구와 IP 50~70% 처리구들 간 뚜렷한 차이를 나타내었다. 엽면적은 50% 이상의 처리구에서 40%이하의 처리구에 비해 50~100%정도 더 넓었고, 건물중도 30%~60% 정도 더 무거웠다. IP 50% 이상 처리구에서 건물 중의 유의한 차이는 없었다. 급액시점(X)은 파프리카 묘의 엽면적(Y₁)과 Y₁=48.311x+133.7(R² = 0.9116^⁎⁎), 건물중(Y₂)과는 Y₂=0.1584x+0.8616(R² = 0.8853^⁎)의 선형회귀관계를 나타내었다. 따라서 본 연구 조건에서 파프리카 육묘 시 처리 간 엽면적과 건물생산량을 고려하였을 때 수분함량 100%인 암면큐브 무게의 50%에 급액하는 것이 적합하고 경제적일 것으로 생각된다.

• Experimental and Molecular Medicine
• /
• 제50권11호
• /
• pp.10.1-10.11
• /
• 2018

Although early studies suggested that bladder cancer (BCa) is more prevalent in men than in women, muscle-invasive rates are higher in women than in men, suggesting that sex hormones might play important roles in different stages of BCa progression. In this work, we found that estrogen receptor beta ($ER{\beta}$) could increase BCa cell proliferation and invasion via alteration of miR-92a-mediated DAB2IP (DOC-2/DAB2 interacting protein) signals and that blocking miR-92a expression with an inhibitor could partially reverse $ER{\beta}$-enhanced BCa cell growth and invasion. Further mechanism dissection found that $ER{\beta}$ could increase miR-92a expression at the transcriptional level via binding to the estrogen-response-element (ERE) on the 5' promoter region of its host gene C13orf25. The $ER{\beta}$ up-regulated miR-92a could decrease DAB2IP tumor suppressor expression via binding to the miR-92a binding site located on the DAB2IP 3' UTR. Preclinical studies using an in vivo mouse model also confirmed that targeting this newly identified $ER{\beta}$/miR-92a/DAB2IP signal pathway with small molecules could suppress BCa progression. Together, these results might aid in the development of new therapies via targeting of this $ER{\beta}$-mediated signal pathway to better suppress BCa progression.

• Asian-Australasian Journal of Animal Sciences
• /
• 제13권8호
• /
• pp.1068-1075
• /
• 2000

A study involving nutrient balances and radioisotope labeling techniques was undertaken to study energy and protein metabolism, and glucose kinetics of female crossbred Etawah goats, using 12 weaned (BW $14.0{\pm}2.0kg$), 12 late pregnant (BW $27.8{\pm}1.8kg$) and 12 first lactation does (BW $25.0{\pm}5.0kg$). Each class of animal was randomly allotted into 3 dietary treatment groups R1, R2 and R3, that received 100%, 85%, and 70% of ad libitum feed. The rations offered were pellets containing 21.8% CP and 19.3 MJ GE/kg, except for the lactating does who received pellets (17.2% CP and 18.9 MJ GE/kg) and fresh Penisetum purpureum grass. Energy and nitrogen balance studies were conducted during a two-week trial. Daily heat production (HP, estimated by the carbon dioxide entry rate technique), glucose pool and flux were measured. Equations were found for metabolizable energy (ME) and protein intake (IP) requirements for growing goats: ME (MJ/d)=1.87+0.55 RE-0.001 ADG+0.044 RP $(R^2=0.89)$ and IP (g/d)=48.47+2.99 RE+0.029 ADG+0.79 RP $(R^2=0.90)$; for pregnant does: ME (MJ/d)=5.92+0.96 RE-0.002 ADG+0.003 RP $(R^2=0.99)$ and IP (g/d)=58.34+5.41 RE+0.625 ADG-0.30 RP $(R^2=0.98)$; and for lactating does: ME (MJ/d)=4.23+0.713 RE+0.003 ADG+0.006 RP+0.002 MY $(R^2=0.86)$; IP (g/d)=84.05-5.36 RE+0.055 ADG-0.16 RP+0.068 MY $(R^2=0.45)$, where RE is retained energy (MJ/d), ADG is average daily gain in weight (g/d), RP is retained protein (g/d) and MY is milk yield (ml/d). ME and IP requirements for maintenance for growing goats were 0.46 MJ/d.kg $BW^{0.75}$ and 7.43 g/d.kg $BW^{0.75}$, respectively. Values for the pregnant and lactating does were in the same order, 0.55 MJ/d.kg $BW^{0.75}$ and 11.7 g/d.kg $BW^{0.75}$, and 0.50 MJ/d.kg $BW^{0.75}$ and 10.8 g/d.kg $BW^{0.75}$, respectively. Milk protein ranged from 3.06 to 3.5% and milk fat averaged 5.2%. Glucose metabolism in Etawah crossbred female goat is active, but glucose flux is low compared to temperate ruminant breeds which may implicate its role to support production.

• 대한디지털의료영상학회논문지
• /
• 제10권2호
• /
• pp.23-31
• /
• 2008

Computed radiography(CR) has been widely used in the field of diagnostic radiography since digital X-ray image was introduced. The imaging performance of CR system was studied by analyzing the digital image data of the CR images which are the outcomes of the whole imaging system composed of image plate(IP), laser digitizer, analoge-digital convertor, and a given image processing unit. In this study, we used a conventional CR system made by Agfa. From the flat field image of 150$\times$150 image pixels, signal-to-noise ratio(SNR) was calculated. SNR of the CR image increases in proportion to logarithm value of the X-ray exposure irradiated on the IP. SNR is less than about 6 at the exposure below 0.2mR and is more than 10 at the exposure above 0.54mR. In our study, most of images obtained by the smaller exposures less than 2.0mR can not be readable. In general, the minimum value of the SNR ranges from 3 to 5. We obtained modulation transfer function(MTF) by analyzing the bar pattern image which was made under conditions as follows: X-ray tube potential was 55kVp, the IP exposure was 0.54 mR, and the distance between X-ray source to IP was 2m, where bar pattern was located on the IP. MTF is 23% at 2.5lp/mm spatial frequency. Provided that the MTF of noise equivalent modulation is 10%, the CR system has the limiting spatial resolution of 3.2lp/mm. If the image sharpness is evaluated by the spatial frequency where MTF is 50%. the corresponding spatial frequency is 0.5$\sim$0.75lp/mm. MTFA(Modulation Transfer Function Area) is 1.0lp/mm. Compared with the Fuji CR whose MTFA is 1.1lp/mm, Agfa CR in this study shows almost same MTFA performance.

• 전자공학회지
• /
• 제33권8호
• /
• pp.63-73
• /
• 2006

본 고는 IMS 기반 NGN 기술동향에 대해 기술하고 IMS기반 NGN의 기본 구조 및 현재 진행상황을 정리한다. 3GPP IMS는 SIP 시그널링을 기반으로 IP 멀티미디어 서비스를 제공하기 위해 Release 5(R5)에서 제안되었으며 현재 Relase 7(R7)을 진행 중에 있다. 이와 함께 ITU-T, ETSI 등에서도 VoIP 기술을 기반으로 차세대네트워크의 구조에 대한 다양한 연구를 수행하고 있으며 공통적으로 3GPP의 IMS 기반을 활용한 독자적인 망 구조를 설계하고 있다. 본 고에서는 3GPP IMS의 기반 구조 및 R6, R7등의 진행상황, 국제 NGN 표준화 진행상황, ITU-T에서의 IMS기반 NGN, TISPAN에서의 IMS기반 구조를 설명한다.