• 제목/요약/키워드: $I^{131}$ scanning

검색결과 16건 처리시간 0.021초

갑상선 재발암의 진단과 치료에 대한 고찰 (Diagnosis and Treatment of the Recurrent Thyroid Cancer)

  • 권오경;박성길;오성수
    • 대한두경부종양학회지
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    • 제16권1호
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    • pp.58-63
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    • 2000
  • Objectives: To demonstrate effective diagnostic method and proper management of recurrent thyroid cancer through to compare treatment and surveillance of $I^{131}$ scanning detected recurrence and clinically detected recurrence. Material and Methods: We retrospectively analyzed clinical information about 46 patients who has recurrent thyroid cancer of 298 patients who have been primarily operated due to thyroid cancer in PMC at the over 10 years between 1986 and 1995. We examine incidence of recurrence due to pathologic types, site of recurrence, disease free interval, detection method of recurrence, and also treatment and progression of recurrence. A patients in which the clinical examination was entirely negative and the $I^{131}$ scan demonstrated either a new area of $I^{131}$ uptake or an increased area of concentration, compared to the previous scan, was designated as a recurrence detected by $I^{131}$ scan only. Recurrences that were obviously by physical examination or chest x-ray, etc were considered clinically detected recurrence, regardless of the the results of the thyroid scan. Results: Mean of disease tree interval(DFI) is 36months. When mean DFI of $I^{131}$ scan detected recurrence is 28months, whereas mean DFI of clinically detected recurrence is 47months. In statiscal analysis, p-value is 0.043 as significantly. In progression of recurrent patient, NED is 28case, AWD is Sease, DOD is 13case. Among the 13case, scan detected recurrence is lease of 20 patients(5%), whereas clinically detected recurrence is l2case of 26 patient(46%). In statiscal analysis, p-value is 0.003 as significantly. Conclusion: Early detection of the recurrent thyroid cancer by $I^{131}$ scanning leads to good progress compare with detection by clinical examination. NED: No Evidence of Disease AWD : Alive With Disease DOD : Dead Of Disease DOC: Dead of Other Cause

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$^{99m}Tc$ Pertechnetate를 사용(使用)한 뇌(腦)스캐닝 (Technetium 99m Pertechnetate Brain Scanning)

  • 이상민;박진영;이안기;정주일;홍창기;이종헌;고창순
    • 대한핵의학회지
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    • 제2권1호
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    • pp.59-66
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    • 1968
  • Technetium 99m pertechnetate brain scanning were performed in 3 cases of head injury (2 chronic subdural hematomas and 1 acute epidural hematoma), 2 cases of brain abscess and I case of intracerebral hematoma associated with arteriovenous anomaly. In all the cases brain scintigrams showed "hot areas." Literatures on radioisotope scanning of intracranial lesions were briefly reviewed. With the improvement of radioisotope scanner and development of new radiopharmaceuticals brain scanning became a safe and useful screening test for diagnosis of intracranial lesions. Brain scanning can be easily performed even to a moribund patient without any discomfort and risk to the patient which are associated with cerebral angiography or pneumoencephalography. Brain scanning has been useful in diagnosis of brain tumor, brain abscess, subdural hematoma, and cerebral vascular diseases. In 80 to 90% of brain tumors positive scintigrams can be expected. Early studies were done with $^{203}Hg$-Neohydrin or $^{131}I$-serum albumin. With these agents, however, patients receive rather much radiation to the whole body and kidneys. In 1965 Harper introduced $^{99m}Tc$ to reduce radiation dose to the patient and improve statistical variation in isotope scanning.

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분화 갑상선 암의 추적 관찰에서 진단적 I-123 전신 스캔의 최적 영상 시점: 동일 환자에서 6시간과 24시간 영상의 비교 (Optimal Imaging Time for Diagnostic I-123 Whole Body Scan in the Follow-up of Patients with Differentiated Thyroid Cancer: Comparison between 6- and 24-Hour Images of the Same Subjects)

  • 이홍제;이상우;송봉일;장성민;서지형;유정수;안병철;이재태
    • Nuclear Medicine and Molecular Imaging
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    • 제43권2호
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    • pp.129-136
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    • 2009
  • 목적: I-123 진단 스캔은 분화 갑상선암 환자의 추적 관찰에 주요한 역할을 하고 있다. 이 연구는 분화 감상선암 환자의 재발과 전이를 발견하는데 있어서 5시간과 24시간 I-123진단 스캔을 비교하여 최적 영상 시점을 찾고자 하였다. 대상 및 방법: 분화 갑상선 암으로 진단되어 갑상선 절제술과 고용량 방사성옥소 치료를 받은 후 추적 관찰 중에 185 MBq(5 mCi)의 I-123으로 6시간과 24시간 진단적 전신 스캔을 시행한 498명의 환자들(남:녀=55:443, 연령: $47.6{\pm}12.9$ 세)을 대상으로 하였다. 같은 시기에 모든 환자들에서 혈액 검사와 경부 초음파를 시행하였다. 추가적인 방사성옥소 치료를 시행한 40명의 환자에서는 치료 후 I-131 스캔을 얻었으며 I-123 진단 스캔과 비교하였다. 결과: 총 498명의 환자들 중 440명(88.4%)에서 6시간과 24시간 영상이 일치하는 결과를 보였으며, 58명(11.6%)에서는 두 영상의 결과가 일치하지 않았다. 불일치를 보이는 58명 중 6시간 영상에서만 이상 섭취를 보이는 31명의 환자들은 모두 위양성 소견을 보였으며, 24시간 영상에서만 이상 섭취를 보이는 12명의 환자들에서는 4명의 잔류 갑상선 조직과 3명의 경부 림프절 전이가 확인되었고, 24시간 영상에서 더 뚜렷한 소견을 보이는 15명 중에서는 2명의 잔류 갑상선 조직과 1명의 경부 림프절 전이가 확인되었다. 추가적인 방사성옥소 치료가 시행된 40명 중 13명에서 두 영상이 불일치를 보였는데, 6시간 영상에서만 이상 섭취가 관찰되는 경우는 모두 위양성 소견을 보였고 24시간 영상은 치료 후 I-131 스캔과 일치하는 결과를 보였다. 결론: 갑상선 환자의 전이 및 재발의 추적 관찰에 있어서 I-123 24시간 영상이 6시간 영상에 비해 진단의 정확도가 더 우수하고 위양성을 줄일 수 있었다.

Prepyrolysis Structural Relaxation of Coal Studied by Differential Scanning Calorimetry and Solvent Swelling

  • Yun, Yongseung;Suuberg, E.M.
    • 한국에너지공학회:학술대회논문집
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    • 한국태양에너지학회, 한국에너지공학회 1993년도 춘계 공동학술발표회 초록집
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    • pp.126-131
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    • 1993
  • Differential Scanning Calorimetry (DSC) and solvent swelling technique have been applied for identifying physical transition temperatures in the macromolecular structure of coals. The transition processes seem to be associated with physical relaxation of the coal structure and are irreversible processes. In Pittsburgh No. 8 high volatile bituminous (hvb) coat one physical transition was noted at 250-30$0^{\circ}C$ (at 8$^{\circ}C$/min) without any significant accompanying weight loss. Coals of higher rank than high volatile bituminous, i.e., Upper Freeport medium volatile bituminous (mvb) and Pocahontas No.3 low volatile bituminous (lvb) coals, exhibit structural relaxation just before the major thermal decomposition process and a sharp increase in solvent swellability accompanies this relaxation. In the case of both the Pittsburgh No.8 and the Upper Freeport coat structural relaxations at around 36$0^{\circ}C$ seem to coincide with release of "guest molecules".les".uot;.

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가족 발생적인 갑상선이상의 방사성면역 측정법에 의한 TSH 평가 (An Evaluation by TSH Radioimmunoassay on Familial Thyroid Disorders)

  • 김지열
    • 대한핵의학회지
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    • 제23권1호
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    • pp.1-6
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    • 1989
  • The occurrence of thyroid disorders is connected with iodine deficiency, defective synthesis or releasing of thyroid hormone and endemicity. Genetic factors are known as a single gene defects, interaction of multiple genes with environmental factors, as well as chromosomal aberrations. Diofnosis thyroid disorders is enforced by I-131 uptake test, thyroid scanning with I-131 or Tc-99 m and serum radioimmunoassays of T3, T4, free T4 and TSH. They were largely classified as hypothyroidism, hyperthyroidism, simple goiter and normal. The pedigree of 58 families was drawn by propositus, and then the correlation between thyroid disorders and TSH levels was analyzed. The results are as follows: 1) The offsprings and their mothers of 15 families were hypothyroidism, THS level was 5 folds for offsprings and 4 folds for mothers in comparison with control group. 2) 13 families were hyperthyyroidism in siblings but their mothers were normal in thyroid function, TSH level of the siblings was lower than control group. 3) Though the offsprings and their mothers of 10 families were similar to TSH level of control group, they are all simple goiter, familial thyroid disorders, in other thyroid function test. The familial thyroid disorders suggested that these transmitted from mothers to offsprings with X-linked dominant or autosomal dominant inheritance.

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과수원용 차량의 자율주행을 위한 적외선 측거 장치개발 (Development of Infrared Telemeter for Autonomous Orchard Vehicle)

  • 장익주;김태한;이상민
    • Journal of Biosystems Engineering
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    • 제25권2호
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    • pp.131-140
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    • 2000
  • Spraying operation is one of the most essential in an orchard management and it is also hazardous to human body. for automatic and unmanned spraying , an autonomous travelling vehicle is demanded. In this study, a telemeter was developed using infrared beam which could detect trunks and obstacles measure distance and direction from the vehicle travelling in the orchard. The telemeter system was composed of two infrared LED transmitters and receivers, a beam scanning device for continuous object detection , two rotary encoders for angle detector, and a beam level controller for uneven soil surface. The detected distance and direction signal s were sent to personal computer which made for the system display the angular and distance measurements through I/O board. According to a field test in an apple farm, the system detected up to 10m distance under 12 V of transmitted beam intensity, however, it was recommended that the proper beam transmit intensity be 7 v at the 10 m distance, because of the negative effect to human body at 12 V. The error rate of this system was 0.92 % when the actual distance was compared to measured one. The system was feasible at the small error rate. The developed telemeter system was an important part for autonomous travelling vehicle provided the real time object recognition . A direction control system could be constructed suing the system. It is expected that the system could greatly contribute to the development of autonomous farm vehicle.

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