• Title/Summary/Keyword: $Henoch-Sch{\ddot{o}}nlein$ purpura

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Acute Epstein-Barr Virus Hepatitis in a 32 Month Old Female Manifesting as Henoch-Sch$\ddot{o}$nlein Purpura

  • Kim, Hee Jin;Jung, Su Jin;Lee, Jun Ho
    • Childhood Kidney Diseases
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    • v.19 no.1
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    • pp.39-42
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    • 2015
  • Henoch-Sch$\ddot{o}$nlein purpura can result from exposure to an antigen after infection with several types of organisms. However, Henoch-Sch$\ddot{o}$nlein purpura caused by a primary Epstein-Barr virus infection has been rarely reported. Here, we report the case of a 32-month-old female patient who presented with Henoch-Sch$\ddot{o}$nlein purpura. Based on abnormal liver function test results and positive results for Epstein-Barr virus infection markers, a diagnosis of Epstein-Barr virus hepatitis manifesting as Henoch-Sch$\ddot{o}$nlein purpura was made. Treatment with methyl-prednisolone and hydration improved the symptoms, and a switch to oral steroids was effective in completely alleviating the purpura. No recurrence was noted and no liver function abnormalities were detected during the follow up period.

Henoch-Sch$\ddot{o}$nlein Purpura in Pediatric Surgery (소아외과에서의 Henoch-Sch$\ddot{o}$nlein 자반증)

  • Kim, Dae-Yeon;Kim, Seong-Chul;Kim, In-Koo
    • Advances in pediatric surgery
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    • v.6 no.1
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    • pp.45-49
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    • 2000
  • Henoch-Sch$\ddot{o}$nlein purpura is a systemic vasculitis of unknown etiology that is probably related to an autoimmune phenomenon. Henoch-Sch$\ddot{o}$nlein purpura is characterized by a purpuric rash, arthralgia, nephritis, and gastrointestinal manifestations. We reviewed 169 children hospitalized with a diagnosis of Henoch-Sch$\ddot{o}$nlein purpura between 1989 and 1998. One-hundred thirty-nine (82.2 %) had gastrointestinal findings including abdominal pain, nausea, vomiting and gastrointestinal bleeding. Surgical consultations were obtained for ten children, and laparotomy was performed in five. Three children suspected of having appendicitis underwent appendectomy. None had appendicitis. One child thought to have been intestinal strangulation was found to have hemorrhagic edema of the proximal jejunum and of the distal ileum. Another child underwent resection for an hemorrhagic infarct of the distal ileum. A high index of suspicion of this disease entity in the differential diagnosis of abdominal pain in children can avoid unnecessary laparotomy in most cases. However, life-threatening gastrointestinal complications may occur in low percentage of cases. Prompt recognition and adequate radiologic evaluation of the abdominal manifestation of this entity is necessary for early surgical intervention.

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A Case of Microscopic Polyangiitis Initially Suspected with Henoch-Sch$\ddot{o}$nlein Purpura Nephritis (Henoch-Sch$\ddot{o}$nlein 자반병 신염으로 의심했던 현미경적 다발혈관염 1례)

  • Im, Jong Geun;Moon, Kyung Chul;Koo, Ja Wook
    • Childhood Kidney Diseases
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    • v.16 no.2
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    • pp.132-137
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    • 2012
  • Microscopic polyangiitis (MPA) is systemic small vessel vasculitis that is very rare in childhood. MPA is characterized by pauci-immune necrotizing small vessel vasculitis without clinical or pathological evidence of necrotizing granulomatous inflammation. Approximately 90% of patients have glomerulonephritis that is accompanied by a variety of other organ involvement. A 10-year-old girl visited our clinic with clinical manifestations suggestive Henoch-Sch$\ddot{o}$nlein purpura nephritis such as purpuric skin rash, abdominal pain, arthralgia on both knees, massive proteinuria and microscopic hematuria. So initially we suspected Henoch-Sch$\ddot{o}$nlein purpura nephritis. However, later her perinuclear-antineutrophil cytoplasmic antibodies(p-ANCA) test was positive, and her renal biopsy was consistent with microscopic polyangiitis. We began steroid therapy, combined with cyclophosphamide, ACE inhibitor. Currently she is a 12-year old, and until now she has been regularly examined in the outpatient. We report a case of microscopic polyangiitis initially suspected with Henoch-Sch$\ddot{o}$nlein purpura nephritis.

A Case of Henoch-Schönlein Purpura Associated with Mycoplasma Pneumoniae Pneumonia (Mycoplasma pneumoniae 폐렴에 동반된 Henoch-Schönlein purpura 1례)

  • Kim, Jong Jin;Cha, Jae Kook;Lee, Kon Hee;Yoon, Hye Sun
    • Pediatric Infection and Vaccine
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    • v.4 no.2
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    • pp.271-275
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    • 1997
  • We experienced a case of Henoch-Sch$\ddot{o}$nlein purpura associated with Mycoplasma pneumoniae pneumonia in a 28 month old male who suffered from cough, abdominal pain and both leg swelling and pain. Physical examination showed varying sized purpura, characteristic of Henoch-Sch$\ddot{o}$nlein purpura, below both knee. Laboratory test revealed Mycoplasma pneumoniae antibody titer >1:2,560 and cold agglutinins titer 1:64. Chest X-ray showed peribronchial blurring in both lung fields. The patient was treated with midecamycin and prednisolone for 7 days and responded to the treatment well. The authors report a case of Henoch-Sch$\ddot{o}$nlein purpura with Mycoplasma pneumoniae pneumonia with brief review of related literatures.

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A Case of Protein Losing Enteropathy Associated with Henoch-Schönlein Purpura (Henoch-Schönlein 자반증에서 발생된 단백소실장증 1례)

  • Kim, Kee Dae;Oh, Chang Whan;Lee, Eun Young;Kim, Jae Young
    • Clinical and Experimental Pediatrics
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    • v.48 no.2
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    • pp.224-227
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    • 2005
  • Henoch-$Sch{\ddot{o}}nlein$ purpura(HSP) is an IgA mediated immune complex vasculitic disease characterized by non-thrombocytic purpura, arthritis, gastrointestinal manifestations, and glomerulonephritis. HSP related glomerulonephritis induces hypoproteinemia and edema in some cases. Protein-losing enteropathy is another rare but known manifestation of HSP leading to hypoproteinemia and edema. We report a 6-year-old girl with HSP who showed edema caused by intestinal protein loss, evidenced by elevated fecal alpha 1 antitrypsin clearance.

A Case of Wegener's Granulomatosis with Delayed Diagnosis due to Clinical Features of Henoch-Schönlein Purpura (Henoch-Schölein 자반증 임상양상으로 나타나 진단이 늦어졌던 웨게너 육아종증 1예)

  • Song, Se Bin;Choi, Hye Sook;Kim, Yee Hyung;Choi, Cheon Woong;Park, Myung Jae;Yoo, Jee-Hong;Kang, Hong Mo;Kim, Yoon Hwa;Park, Joo Cheol
    • Tuberculosis and Respiratory Diseases
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    • v.63 no.6
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    • pp.531-536
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    • 2007
  • Wegener's granulomatosis is a systemic vasculitis of the medium and small arteries, as well as of the venules, arterioles, and occasionally large arteries, and primarily involves the upper and lower respiratory tracts and the kidneys. Renal symptoms of Wegener's granulomatosis are indistinguishable from those of vasculitis such as Henoch-$Sch\ddot{o}nlein$ purpura and microscopic polyangiitis. This case, though initially diagnosed as Henoch-$Sch\ddot{o}nlein$ purpura, was confirmed as Wegener's granulomatosis from a lung biopsy fifteen years after the initial diagnosis. We report this case with a review of the literature.

Two Cases Suggesting the Relationship of IgA Nephropathy and Henoch-$Sch{\ddot{o}}nlein$ Purpura (IgA Nephropathy와 Henoch-$Sch{\ddot{o}}nlein$ Purpura가 동일 병인임을 시사하는 2례)

  • Jeong Dong-Ho;Song Chang-Ju;Kim Deok-Su;Ha Tae-Sun
    • Childhood Kidney Diseases
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    • v.5 no.1
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    • pp.59-63
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    • 2001
  • There are a considerable number of reports suggesting a common pathogenesis of IgA nephritis(IgANn) Henoch-$Sch{\ddot{o}}nlein$ Purpura(HSP). In previous reports, a patient develops IgAN after kidney transplantation for HSP nephritis, one of Identical twin boys, developed IgAN and the other HSP, and a boy with IgAN later developed HSP. We report two cases, one with IgAN who later developed HSP and the other with HSP who later developed IgAN, suggesting that IgAN and HSP have a common pathogenesis. (J. Korean Soc Pediatr Nephrol 5 : 59- 63, 2001)

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Acute Epididymitis in Two Children with Henoch-Sch$\ddot{o}$nlein Purpura (Henoch-Sch$\ddot{o}$nlein 자반증에서 동반된 급성 부고환염)

  • Lee, Kyoung-Ah;Park, Se-Jin;Shin, Jae-Il
    • Childhood Kidney Diseases
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    • v.15 no.2
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    • pp.184-190
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    • 2011
  • Scrotal involvement has been reported from 2% to 38% of males with Henoch-Sch$\ddot{o}$nlein purpura (HSP). It may present before the rash occurs or even long time after it has disappeared. Scrotal involvement of HSP usually results in pain, tenderness, swelling or discoloration of scrotum. Scrotal pain sometimes mimics testicular torsion to various degrees, which can be followed by unnecessary operation. In our 2 cases, one was a 5-year and 11-month-old boy who came to our emergency department due to scrotal pain before the diagnosis of HSP, and the other was a 5-year and 1-month-old boy who came to the outpatient clinic due to scrotal pain after the resolution of HSP about 1 month before the visit. We performed Doppler ultrasonography (USG) to evaluate the acute scrotal pain in the two boys. On Doppler USG, epididymis showed increased blood flow, and testis showed normal blood flow. These findings enabled the diagnosis of acute epididymitis and excluded testicular torsion. Epididymitis was improved by conservative management including shortterm steroid therapy within 5 days. It is important to perform adequate evaluation with tools such as Doppler USG in the early course of acute scrotum of HSP, to avoid unnecessary scrotal exploration.

Poststreptococcal Glomerulonephritis Mimicking Henoch-$Sch{\ddot{o}}nlein$ Purpura (신생검에서 급성 사구체신염 양상을 보인 Henoch-$Sch{\ddot{o}}nlein$ 자반증 2례)

  • Lee Sang Heun;Namgoong Mee Kyung;Cha Byung Ho;Kim Jong Soo
    • Childhood Kidney Diseases
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    • v.2 no.2
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    • pp.192-195
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    • 1998
  • [ $\beta$ ]-streptococci have been reported as an etiology of Henoch-$Sch{\ddot{o}}nlein$ purpura(HSP), but the role of $\beta$-streptococci in HSP is not yet confirmed. Our report of two HSP patients is as follows : Although the two patients' clinical symptoms resembled those symptoms of HSP, whereas serum $C_3$ decreased in one case, ASO titer increased in both cases and a histological examination of renal biopsy specimens revealed the fetures commonly described in poststreptococcal glomerulonephritis.

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Two Cases of Henoch-$Sch{\ddot{o}}nlein$ Purpura in one Family at Similar Period (남매에서 비슷한 시기에 발생한 Henoch-$Sch{\ddot{o}}nlein$ 자반증 2례)

  • Kim, So-Young;Lim, In-Seok;Yoo, Byoung-Hoon
    • Childhood Kidney Diseases
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    • v.4 no.2
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    • pp.161-165
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    • 2000
  • Henoch-$Sch{\ddot{o}}nlein$ purpura(HSP) frequently follows upper respiratory infection, and one of the causes of this discase is inferred to $\beta$-hemolytic streptococcal infection, but the relationship is still unclear. familial tendency of this disease is unclear, too. Also genetic relationship of this disease has been in a controversy yet. We experienced two cases of HSP in brother and sister at similar period, and report this case with review of related literatures.

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