• Title/Summary/Keyword: $D^*S$

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The Relationship Between Delamination Element and Delamination Growth (층간분리 요소와 층간분리 성장의 관계)

  • 송삼홍;김철웅;홍정화;김태수;황진우
    • Proceedings of the Korean Society For Composite Materials Conference
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    • 2003.04a
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    • pp.113-116
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    • 2003
  • The investigation of delamination growth behavior in hybrid composite material such as FRMLs should be considered delamination growth rate, dA_D/da$ using the delamination shape factor, $f_S$ instead of traditional fracture mechanics parameters. The main objective of this study is to evaluate the relationship between delamination element (i. e. delamination width, b, delamination contour, c, delamination shape factor, $f_S$ and delamination growth rate, dA_D/da$) and delamination growth in FRMLs under cyclic bending moment. The delamination shape formed along the fatigue crack between aluminum layer and glass fiber/epoxy layer are measured by scanning method. The details of study are as follow : ⅰ) Relationship between crack length, a and delamination width, b. ⅱ) Variation of delamination growth rate, dA_D/da$ was attendant on delamination shape factors, $f_{S1}$, $f_{S2}$, $f_{S3}$. The test result indicated the delamination growth behavior depends in delamination element such as delamination width, b, delamination shape factors, $f_{S1}$, $f_{S2}$, $f_{S3}$.

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Comparison and evaluation between 3D-bolus and step-bolus, the assistive radiotherapy devices for the patients who had undergone modified radical mastectomy surgery (변형 근치적 유방절제술 시행 환자의 방사선 치료 시 3D-bolus와 step-bolus의 비교 평가)

  • Jang, Wonseok;Park, Kwangwoo;Shin, Dongbong;Kim, Jongdae;Kim, Seijoon;Ha, Jinsook;Jeon, Mijin;Cho, Yoonjin;Jung, Inho
    • The Journal of Korean Society for Radiation Therapy
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    • v.28 no.1
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    • pp.7-16
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    • 2016
  • Purpose : This study aimed to compare and evaluate between the efficiency of two respective devices, 3D-bolus and step-bolus when the devices were used for the treatment of patients whose chest walls were required to undergo the electron beam therapy after the surgical procedure of modified radical mastectomy, MRM. Materials and Methods : The treatment plan of reverse hockey stick method, using the photon beam and electron beam, had been set for six breast cancer patients and these 6 breast cancer patients were selected to be the subjects for this study. The prescribed dose of electron beam for anterior chest wall was set to be 180 cGy per treatment and both the 3D-bolus, produced using 3D printer(CubeX, 3D systems, USA) and the self-made conventional step-bolus were used respectively. The surface dose under 3D-bolus and step-bolus was measured at 5 measurement spots of iso-center, lateral, medial, superior and inferior point, using GAFCHROMIC EBT3 film (International specialty products, USA) and the measured value of dose at 5 spots was compared and analyzed. Also the respective treatment plan was devised, considering the adoption of 3D-bolus and stepbolus and the separate treatment results were compared to each other. Results : The average surface dose was 179.17 cGy when the device of 3D-bolus was adopted and 172.02 cGy when step-bolus was adopted. The average error rate against the prescribed dose of 180 cGy was -(minus) 0.47% when the device of 3D-bolus was adopted and it was -(minus) 4.43% when step-bolus was adopted. It was turned out that the maximum error rate at the point of iso-center was 2.69%, in case of 3D-bolus adoption and it was 5,54% in case of step-bolus adoption. The maximum discrepancy in terms of treatment accuracy was revealed to be about 6% when step-bolus was adopted and to be about 3% when 3D-bolus was adopted. The difference in average target dose on chest wall between 3D-bolus treatment plan and step-bolus treatment plan was shown to be insignificant as the difference was only 0.3%. However, to mention the average prescribed dose for the part of lung and heart, that of 3D-bolus was decreased by 11% for lung and by 8% for heart, compared to that of step-bolus. Conclusion : It was confirmed through this research that the dose uniformity could be improved better through the device of 3D-bolus than through the device of step-bolus, as the device of 3D-bolus, produced in consideration of the contact condition of skin surface of chest wall, could be attached to patients' skin more nicely and the thickness of chest wall can be guaranteed more accurately by the device of 3D-bolus. It is considered that 3D-bolus device can be highly appreciated clinically because 3D-bolus reduces the dose on the adjacent organs and make the normal tissues protected, while that gives no reduction of dose on chest wall.

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Design and Fabrication of Active Type Patch Antenna for S-DMB (위성 DMB용 능동형 패치 안테나의 설계 및 제작)

  • Yun, Li-Ho;Kim, Byung-Mun
    • 전자공학회논문지 IE
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    • v.45 no.4
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    • pp.54-59
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    • 2008
  • In this paper, circularly polarized patch antenna with 2-stage LNA for the reception of S-DMB is presented. It used teflon didelectric substrate of ${\in}_r$=2.2 and the size is $40{\times}40{\times}15\;[mm]$. Experimental results of fabricated antenna show that bandwidths of input return loss and axial ratio are about 22 [MHz] and 25 [MHz]. Input return loss, output return loss, gain, and noise figure of the fabricated 2-stage LNA are $S_{11}$=-14 [dB], $S_{22}$=-18 [dB], $S_{21}$=26.8 [dB], and NF=1.14 [dB] respectively. The fabricated active type antenna has total gain of 30.4 [dB] at 2.642 [GHz].

Effects of the X Chromosome on the Formation of Sex Comb and Genital Aech in the Hybrids between Drosophila simulans and D. Mauritiana (Drosophila simulans와 D. mauritiana 사이 종간잡종의 성즐과 생식궁 형성에 미치는 X 염색체의 효과)

  • 최영현;유미애;이원호
    • Korean journal of applied entomology
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    • v.35 no.3
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    • pp.216-220
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    • 1996
  • Drosophila simulans and D. mauritiana are sibling species, the former cosmopolitan and the latter restricted to the oceanic island of Mauritius. Sex comb-tooth number of male flies of D. simulans were about 9.83, while those of D. mauritiana were 12.90. Genital arch of D. simulans is large semicircular shaped expasion, while that of D. mauritiana is a narrow fingerlike expansion. We used classical genetic analysis to measure effects of genes on the X chromosome responsible for numeral and morphological differences in sex comb-tooth and genital arch between these species, respectively. For these purposes, mutant strain of D. simulans and wild type strain of D. mauritiana were hybridized and males of the FI and the backcrossed progenies were compared with two characters above mentioned. The sex comb-tooth number of F, males were about 11.79, and the genitalia of F, male were intermediate in shape between those of D. simulans and D. mauritiana. Genetic analysis of sex comb-tooth number and genital arches differing between D. simulans and D. mauritiana showed that very little diffemce was due to effect of the X chromosome.

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Relationship between R&D Investment and Firm Value by Characteristics of CEO: Focused on Venture Business (경영자 특성에 따른 R&D 투자와 기업가치 관련성: 벤처기업을 중심으로)

  • Kim, Yi-Jin;Kim, Jeong-Eun;Jeon, Seong-Il
    • Korean small business review
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    • v.41 no.1
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    • pp.75-96
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    • 2019
  • This study used age, education, major, working period as CEO's characteristics and examine relationship between these characteristics and R&D Investment. Furthermore this study examined how CEO should react in terms of R&D investment, which is effected by CEO's characteristic in the market. The empirical results are following. (1) When CEO's age are young, they spend much money for R&D investment. And R&D investment which is determined by young CEO has a positive effect on relation of firm value. (2) A higher educational background has a positive effect on R&D investment and will create higher firm value. (3) When CEO's major is competitive in the same industry, it has a positive relationship with R&D investment and its firm value is bigger than though. (4) When CEO working period is long, they showed active to R&D investment. On the other hand, the firm value decreased. This study focused on analyzing the relationship between characteristics of CEO and R&D Investment, furthermore, how R&D investment which effected by CEO's characteristic is contributing in creating the firm value. This results indicate that CEO's characteristics reflect R&D investment and value of venture business. Therefore, CEO's characteristics should be considered financial information and firm value in the market.

Effect of Nutrient Solution Strength on Growth of Phalaenopsis in an Ebb and Flow System (Ebb and Flow 시스템을 이용한 호접란 수경재배시 생장에 미치는 배양액 농도의 영향)

  • An, Dong-Choon;Park, Seon-Hye;Been, Chul-Gu;Jeong, Byoung-Ryong
    • Journal of Bio-Environment Control
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    • v.16 no.3
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    • pp.199-204
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    • 2007
  • This experiment was conducted to investigate the effect of nutrient solution strength on the growth of miniature multiflora P. amabilis and P. Taisuco Red Jewel at two growth stages during four months cultivation in an ebb and flow system. Early stage plants gained the biggest leaf length and width when nutrient solution strength was EC 0.5 or $1.0dS{\cdot}m^{-1}$ in P. amabilis, and EC $1.5dS{\cdot}m^{-1}$ in P. Taisuco Red Jewel. Root length and weight were the greatest when nutrient solution strength was EC $0.5dS{\cdot}m^{-1}$ in both cultivars and this trend was also found in middle stage plants. Fresh and dry weights of leaves increased as nutrient solution strength was elevated and were the greatest when nutrient solution strength was EC $1.5dS{\cdot}m^{-1}$ in P. amabilis. On the contrary elevation of nutrient solution strength decreased fresh weight of roots, being the greatest when nutrient solution strength was EC $0.5dS{\cdot}m^{-1}$. This trend was also found in P. Taisuco Red Jewel and P. amabilis at middle growth stage. The T/R ratio and chlorophyll content increased with nutrient solution strength and were the greatest regardless of cultivar and growth stage when nutrient strength was EC $1.5dS{\cdot}m^{-1}$.

RNA polymerase I subunit D activated by Yin Yang 1 transcription promote cell proliferation and angiogenesis of colorectal cancer cells

  • Jianfeng Shan;Yuanxiao Liang;Zhili Yang;Wenshan Chen;Yun Chen;Ke Sun
    • The Korean Journal of Physiology and Pharmacology
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    • v.28 no.3
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    • pp.265-273
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    • 2024
  • This study aims to explore possible effect of RNA polymerase I subunit D (POLR1D) on proliferation and angiogenesis ability of colorectal cancer (CRC) cells and mechanism herein. The correlation of POLR1D and Yin Yang 1 (YY1) expressions with prognosis of CRC patients in TCGA database was analyzed. Quantitative realtime polymerase chain reaction (qRT-PCR) and Western blot were applied to detect expression levels of POLR1D and YY1 in CRC cell lines and CRC tissues. SW480 and HT-29 cells were transfected with si-POLR1D or pcDNA3.1-POLR1D to achieve POLR1D suppression or overexpression before cell migration, angiogenesis of human umbilical vein endothelial cells were assessed. Western blot was used to detect expressions of p38 MAPK signal pathway related proteins and interaction of YY1 with POLR1D was confirmed by dual luciferase reporter gene assay and chromatin immunoprecipitation (ChIP). TCGA data showed that both POLR1D and YY1 expressions were up-regulated in CRC patients. High expression of POLR1D was associated with poor prognosis of CRC patients. The results showed that POLR1D and YY1 were highly expressed in CRC cell lines. Inhibition or overexpression of POLR1D can respectively suppress or enhance proliferation and angiogenesis of CRC cells. YY1 inhibition can suppress CRC progression and deactivate p38 MAPK signal pathway, which can be counteracted by POLR1D overexpression. JASPAR predicted YY1 can bind with POLR1D promoter, which was confirmed by dual luciferase reporter gene assay and ChIP. YY1 transcription can up-regulate POLR1D expression to activate p38 MAPK signal pathway, thus promoting proliferation and angiogenesis ability of CRC cells.