• Journal of Pharmaceutical Investigation
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• v.18 no.3
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• pp.139-144
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• 1988

Piperacillin phthalidyl ester was synthesized by reacting piperacillin with triethylamine and bromophthalide in acetone and its chemical structure was determined by UV, IR, and PMR. The partition coefficient of the ester was increased and the ester was more lipophilic and less water soluble than piperacillin. The ester did not show the antimicrobial activity against Bacillus subtilis ATCC 6633 in vitro, but when hydrolyzed, the parent drug of ester, piperacillin, revealed antimicrobial activity in vivo. After a single oral dose of both piperacillin and the ester to rabbits, the serum piperacillin concentration was measured by bioassay. The ester exhibited improved pharmatokinetic characteristics: $T_{max}\;of\;2hr,\;C_{max}\;of\;4.26{\mu}g{\cdot}ml^{-1},K_{el}\;of\;0.057hr^{-1},\;and\;total\;AUC\;of\;85.42{\mu}g{\cdot}hr{\cdot}ml^{-1}$. Piperacillin on the other hand, did not exhibit any gastro-intestinal absorption.

• Bulletin of the Korean Chemical Society
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• v.23 no.3
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• pp.447-453
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• 2002

In this paper we have presented the results of thermodynamic, structural, and dynamic properties of model systems for liquid benzene, toluene and p-xylene in an isobaric-isothermal (NpT) ensemble at 283.15, 303.15, 323.15, and 343.15 K using molecular dynamics (MD) simulation. This work is initiated to compensate for our previous canonical (NVT) ensemble MD simulations [Bull. Kor. Chem. Soc. 2001, 23, 441] for the same systems in which the calculated pressures were too low. The calculated pressures in the NpT ensemble MD simulations are close to 1 atm and the volume of each system increases with increasing temperature. The first and second peaks in the center of mass g(r) diminish gradually and the minima increase as usual for the three liquids as the temperature increases. The three peaks of the site-site gC-C(r) at 283.15 K support the perpendicular structure of nearest neighbors in liquid benzene. Two self-diffusion coefficients of liquid benzene via the Einstein equation and via the Green-Kubo relation are in excellent agreement with the experimental measures. The self-diffusion coefficients of liquid toluene and p-xylene are in accord with the trend that the self-diffusion coefficient decreases with increasing number of methyl group. The friction constants calculated from the force auto-correlation (FAC) function with the assumption that the fast random force correlation ends at time which the FAC has the first negative value give a correct qualitative trends: decrease with increase of temperature and increase with the number of methyl group. The friction constants calculated from the FAC's are always less than those obtained from the friction-diffusion relation which reflects that the random FAC decays slower than the total FAC as described by Kubo [Rep. Prog. Phys. 1966, 29, 255].

• Journal of Korean Society of Forest Science
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• v.84 no.2
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• pp.166-177
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• 1995

This study was carried out to discuss how soils in the area planned for a forest road construction can be mechanically tested and practically applied. For this, 16 soil test samples from 8 plots(2 samples per plot) were used. The major tests are focused on unit weight before and after cut, water content, liquid and plastic limits, sieve and hydrometer analysis etc. The total unit weight(${\rho}_t$) before and after cut are $1.69g/cm^3$ and $1.19g/cm^3$, respectively. Their water contents are 21.0% and 20.5%. The coefficient of uniformity U and coefficient of curvature C obtained from sieve and hydrometer analysis are 125 and 0.42, which mean generally not well graded. On the soil classification by USCS, SM(silty sand or silt-sand mixed soil)is a Key soil, but it seems to be not good for fill material. From the standard proctor test are resulted $1.40{\pm}0.065g/cm^3$ for the unit weight(${\rho}$) in the nature and $1.88{\pm}0.049g/cm^3$ for the optimum proctor unit weight(${\rho}pr$) each. With this to say, it is necessary more powerful compaction work at earth filling, with which this soil reachs enough the ${\rho}pr$, and more earth.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.53 no.1
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• pp.60-66
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• 2017

This study researched the population of ecological characteristics of the goldeyes rockfish Sebasetes thompsoni sampled by gill net in the Ulleungdo area from February 2013 to February 2014 in order to assess the current stock status and provide scientific advice for management implementation. The instantaneous coefficient of total mortality (Z) was 0.78/year and the survival rate (S) was 0.459. The instantaneous coefficient of natural mortality (M) was 0.461/year. Based on the estimates of Z and M, the instantaneous coefficient of fishing mortality (F) was 0.318/year. The age at first capture ($t_c$) was 4.41/years. Current Yield-per-recruit (YPR) was 30.83 g, and fishing mortality at maximum YPR ($F_{max}$) and fishing mortality corresponding to 10% of the maximum slope in YPR curve ($F_{0.1}$) were 3.257/year and 0.673/year, respectively. $F_{35%}$ and $F_{40%}$, indicating fishing mortalities at 35% and 40% of maximum Spawning biomass-per-recruit (SBPR), were 0.619/year and 0.509/year, respectively. Based on the biological reference points, fishing mortality at overfished threshold yield ($F_{OTY}$) was calculated as 0.509/year. Current $SBPR/SBPR_{MSY}$ was 1.313 above 1.0, which means 'not overfishe,' while current $F/F_{OTY}$ was 0.629 below 1.0, which indicates 'not overfishing.' In conclusion, the current status of goldeyes rockfish was located in green zone (i.e., not overfished and not overfishing) according to the revised Kobe plot.

• Journal of Microbiology
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• v.40 no.2
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• pp.119-124
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• 2002

Experiments for the characterization of inactivation were performed in a series of batch processes with the total coliform used as a general indicator organism based on the chlorine residuals as a disinfectant. The water samples were taken from the outlet of a settling basin in a conventional surface water treat- ment system that is provided with the raw water drawn from the mid-stream of the Han River, The inactivation of total coliform was experimentally analysed for the dose of disinfectants contact time, filtration and mixing intensity. The curves obtained from a series of batch processes were shaped with a general tailing-off and biphasic mode of inactivation, i.e. a sharp loss of bacterial viability within 15 min followed by an extended phase. In order to observe the effect of carry-over suspended solids on chlorine consumption and disinfection efficiency, the water samples were filtered, prior to inoculation with coliforms, with membranes of both 2.5$\mu$m and 11.0 $\mu$m pore size, and with a sand tilter of 1.0 mm in effective size and of 1.4 in uniformity coefficient. As far as the disinfection efficiency is concerned, there were no significant differences. The parameters estimated by the models of Chick-Wat-son, Hom and Selleck from our experimental data obtained within 120 min are: log(N/N$\_$0/)=-0.16CT with n=1, leg(N/N$\_$0/)=-0.71C$\^$0.87/ with n 1 for the Chick-Watson model, log (N/N$\_$0/)=-1.87C$\^$0.47/ T$\^$0.36/ for the Hom model, log (MHo)=-2.13log (1+CT/0.11) for the Selleck model. It is notable that among the models reviewed with regard to the experimental data obtained, the Selleck model appeared to most closely resemble the total coliform survival curve.

• Proceedings of the IEEK Conference
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• 2006.06a
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• pp.227-228
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• 2006

In this paper, we introduce the design and fabrication of 60 GHz low noise amplifier MMIC for IEEE802.15.3c WPAN system. The 60 GHz LNA was designed using ETRI's $0.12{\mu}m$ PHEMT process. The PHEMT shows a peak transconductance ($G_{m,peak}$) of 500 mS/mm, a threshold voltage of -1.2 V, and a drain saturation current of 49 mA for 2 fingers and $100{\mu}m$ total gate width (2f100) at $V_{ds}$=2 V. The RF characteristics of the PHEMT show a cutoff frequency, $f_T$, of 97 GHz, and a maximum oscillation frequency, $f_{max}$, of 166 GHz. The performances of the fabricated 60 GHz LNA MMIC are operating frequency of $60.5{\sim}62.0\;GHz$, small signal gain ($S_{21}$) of $17.4{\sim}18.1\;dB$, gain flatness of 0.7 dB, an input reflection coefficient ($S_{11}$) of $-14{\sim}-3\;dB$, output reflection coefficient ($S_{22}$) of $-11{\sim}-5\;dB$ and noise figure (NF) of 4.5 dB at 60.75 GHz. The chip size of the amplifier MMIC was $3.8{\times}1.4\;mm^2$.

• The Journal of Korean Society for School & Community Health Education
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• v.15 no.3
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• pp.105-125
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• 2014

Background: The purpose of this study was to evaluate reliability and validity of a 27-item Korean Version of the Impact of Weight on Quality of Life in adolescents ($IWQOL-Kids^{(C)}$: Korean Version). Methods: This instrument was administered to 872 adolescents (mean z-BMI: 2.61, mean $age{\pm}SD$: $13.9{\pm}1.2$, male: 51.9%). Reliability was tested by internal consistency method and item analysis, validity test was performed by index of content validity, exploratory factor analysis, confirmatory factor analysis and concurrent validity. Sensitivity was tested by ANOVA and t-test. Analyses were performed using SPSS and Amos 18.0. Results: By an exploratory factor analysis, 4 factors were extracted; 'Body esteem' consisted of 9 items with 35.9% of variance (social life: 6 items, 10.23%, physical comfort: 6 items, 8.21%, family relations: 6 items, 7.0%). Four factors explained 61.34% of total variance. Internal consistency coefficients ranged from .766 to .929 for scales on 27 items and equal to .920 for total score for both the 26-item and 27-item tools. A confirmatory factor analysis was conducted for the convergent validity and discriminant validity. The standardized factor loadings to test the convergent validity showed more than .5(C.R<1.965) on all paths after deletion of item PC1 (avoid stairs). The average variances extracted were more than .50 and the construct reliabilities were more than .70. The average variances extracted were stronger than the squares of correlation coefficient of inter-latent variables. Conclusions: These results support that the $IWQOL-Kids^{(C)}$: Korean Version with a 26-item is a reliable and valid tool in Korean obese adolescents.

• Journal of Korean Society of Rural Planning
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• v.22 no.4
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• pp.147-157
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• 2016

On the purpose to analyze the survival rate of startup companies since their establishment, the companies' survival rate was investigated by surviving period. The average and coefficient of variation(C.V.) of the startup companies' survival rate were examined with the comparison of urban and rural areas, and primary, secondary, and tertiary industries. In this study, the variation of total numbers of new-established companies, from 1998 to 2012, were analyzed with micro-data of the Statistics Korea, 'The Census on Establishments'. The results show that the survival rate of primary industry companies largely fluctuate and don't be stabled during the whole surviving periods, whereas secondary and tertiary industry companies show stabilized survival rate after fifth year from their establishment. Especially, the startup companies of primary industry located at urban areas show the largest fluctuation and the most vulnerable stability of survival rate. It is concluded that the surviving period of primary industry companies don't guarantee their survival, while survival rate of secondary and tertiary industry company became stable after five years from their establishment.

• The Journal of the Korea Contents Association
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• v.14 no.11
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• pp.308-317
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• 2014

The purpose of this study was to investigate factors affecting suicidal ideation in psychiatric inpatients. A total of 186 psychiatric inpatients participated in the study. Data were analyzed by frequencies, t-test, ANOVA, Pearson correlation coefficient, and hierarchical multiple regression with SPSS WIN 18.0. Suicidal ideation showed significant differences according to marital status, diagnosis, and previous suicide attempt history. There were significant correlations among depression, self-esteem, spirituality and suicidal ideation. Depression and spirituality were identified as predictors affecting suicidal ideation. The regression model explained 52.4% of suicidal ideation. As a result, intervention program for decreasing depression and improving spirituality is essential to decrease suicidal ideation in psychiatric inpatients.

• Journal of the Korean Society of Industry Convergence
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• v.11 no.1
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• pp.11-18
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• 2008

After execute quantitative analysis that choose station and compose floodgate quality of water net and use floodgate data and quality of water data analysis target Sign of the cock as 1 dimension access for Non-point pollution source pollution and estimate of Gaeuncheon's at Kyongsangbukdo report to the Throne in this research, presented parameter conclusion notation model (AGNPS) in real condition of our agricultural area through comparison with spot value and result is as following in reply. With result observation and analysis result of the AGNPS model the comparison which it will pay from the hazard which it analyzes 2005, the rainfall thought which is used in the analysis to select 8 heavy rain thoughts 2005 July - is data until of September. Actual amount of rainfall 6.0~195.0 mm one time the antecedent precipitation showed API5 case 0.0~507.0mm and were observed peak flows (Qpeak) each from the P-1 $0.026m^3/sec{\sim}9.265m^3/sec$, from the P-2 $0.010m^3/sec-2.747m^3/sec$ and from the P-3c $0.064m^3/sec-13.482m^3/sec$ to show. Also amendment AMC condition it will be cool and it uses and the AGNPS model conference the result which it occurs, analysis and regression analysis of actual flow for as 0.992 very the possibility of getting the result which is good there was a decisive coefficient which is cool. But the gun is (T-P) with the total nitrogen (T-N) decisive coefficient each as 0.794 and 0.849 the presumption which is reliability generally will pay and with the fact that it will be the possibility of getting it is judged.