• 대한수의학회지
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• 제60권4호
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• pp.203-207
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• 2020

This study presents neuronal migration pattern of dopamine (DA) neurons generated in separate regions occupying the ventral mesencephalic territory. A single pulse 5-bromodeoxyuridine (BrdU) was administered at embryonic day (E)10-E15. Distribution of tyrosine hydroxylase (TH) positive cells was determined at E13-postnatal day 0 (P0) by immunohistochemistry. BrdU positive cells labeled at E10 were spread out uniformly in the mesencephalon from E13 to E15, migrating through dorsal and ventral routes at E17 and P0. TH expression labeled at E10 was observed at E13 in the ventromedial region and clearly formed in the ventral tegmental area (VTA) at E15. At E17, TH expression in the substantia nigra (SN) was observed in the ventrolateral region, spreading more outward of the mesencephalon at P0. Generation of TH-positive cells labeled at E13 was also observed in VTA and SN of the mesencephalon at E17 and P0. The expression of these cells labeled after E15 was markedly decreased. These results demonstrated that an almost complete primary structure of DA neuron was formed at the early embryonic stage in the ventral mesencephalon, showing the most active neuronal migration was occurred at E13-E17.

• IMMUNE NETWORK
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• 제23권1호
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• pp.5.1-5.28
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• 2023

Th cell lineage determination and functional specialization are tightly linked to the activation of lineage-determining transcription factors (TFs) that bind cis-regulatory elements. These lineage-determining TFs act in concert with multiple layers of transcriptional regulators to alter the epigenetic landscape, including DNA methylation, histone modification and threedimensional chromosome architecture, in order to facilitate the specific Th gene expression programs that allow for phenotypic diversification. Accumulating evidence indicates that Th cell differentiation is not as rigid as classically held; rather, extensive phenotypic plasticity is an inherent feature of T cell lineages. Recent studies have begun to uncover the epigenetic programs that mechanistically govern T cell subset specification and immunological memory. Advances in next generation sequencing technologies have allowed global transcriptomic and epigenomic interrogation of CD4+ Th cells that extends previous findings focusing on individual loci. In this review, we provide an overview of recent genome-wide insights into the transcriptional and epigenetic regulation of CD4+ T cell-mediated adaptive immunity and discuss the implications for disease as well as immunotherapies.

• Bulletin of the Korean Chemical Society
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• 제15권1호
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• pp.25-28
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• 1994

Weakly electron withdrawing bromine substituted poly(2-bromo-1,4-phenylenevinylene) (PBrPV) was synthesized th-rough water-soluble precursor method. The linear and nonlinear optical properties of PBrPV were compared with those of poly(1,4-phenylenevinylene) (PPV). The third-order nonlinear optical susceptibility, X^{(3)}$, was measured by using third-harmonic generation (THG) technique at 1907 nm, fundamental wavelength. The calculated $X^{(3)}$ values of PPV and PBrPV were 3${\times}$ 10$^{-12}$ esu and 2${\times}$10$^{-12}$ esu, respectively.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2011년도 정기총회 및 추계학술대회 논문집
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• pp.2031-2036
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• 2011

To leading subway technology Advanced Urban Transit System is developed by national research and development. Next-generation trains equipped with direct driving permanent magnet traction motor and individually controlled propulsion system. Electromagnetic properties of the Next-Generation Train from four perspectives will be discussed. The first is closely related to human hazards that affect the 60Hz low frequency electromagnetic field. The Second is inductive noise that affect railroad signal system. The third is conductive noise that affect communication line near railroad. The 4th is radiation noise that may affect electronic equipment near the railroad tracks.

• 전력전자학회:학술대회논문집
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• 전력전자학회 2001년도 Proceedings ICPE 01 2001 International Conference on Power Electronics
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• pp.236-241
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• 2001

This paper presents a novel prototype of active voltage-clamping capacitor-assisted edge resonant soft switching PWM inverter operating at a constant frequency variable power (VPCF) regulation scheme, which is suitable for consumer high-power induction-heating cooking appliances. New generation IGBT with a trench gate is particularly improved in order to reduce conduction loss due to its lowered saturation voltage characteristics. The soft switching load resonant and quasi-resonant inverter designed distinctively using the latest IGBTs is evaluated from an experimental point of view.

• 한국군사과학기술학회지
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• 제21권2호
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• pp.204-210
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• 2018

As the 4th industrial revolution and artificial intelligence technology develop, it is expected that there will be a revolutionary changes in the security robot. However, artificial intelligence system requires enormous hardwares for tremendous computing loads, and there are many challenges that need to be addressed more technologically. This paper introduces precise tracking control technique of autonomous system that need to move repetitive paths for security purpose. The input feedforward signal is generated by using the inverse based iterative learning control theory for the 2 input 2 output nonminimum-phase system which was difficult to overcome by the conventional feedback control system. The simulation results of the input signal generation and precision tracking of given path corresponding to the repetition rate of extreme, such as bandwidth of the system, shows the efficacy of suggested techniques and possibility to be used in military security purposes.

• 한국식생활문화학회지
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• 제3권4호
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• pp.351-357
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• 1988

A feature of present fomula of dietary habitus is the result of its traditional succession, as like as the newly established culture is rooted in the inherited traditional culture. So, it is very important to discriminate the kind of korean traditional foods and to discuss the historical background of the foods in use, since they have to develope better dietary conditions in furture by using modern theory of dietetics. But there are few literatures concerning to korean traditional foods clear at a glance. However, some traditional foods including technology of cultivation and processing have been transmitted from generation to generation in some districts. Therefore, author has attempted to investigate the history of traditional foods. The results obtained were as follows. 1. A lots of traditional foods which were gifts to imperial court alloted to districts or civilian foods during Choson dynasty have been transmitted up to date, and the method of cultivation and processing are well preserved. Among them out standing examples are: 1) persimmon and its processed goods. 2) red pepper and malted pepper catchup. 3) ginger and its processed goods. 4) honey, bean sprouts etc. 2. It has been reported that ginger was cultivated in China in 5th century B.C. and in Korea early in 16th century. But historical relationships between them could not be confirmed. However, from SAMKUKSAGI and the report by Lee, Suk Woo(1754-1825) who was governor of Chonla province and remarked ginger as a sacred herb at Wanju county, Bongong town, it is suggested that ginger is a natural growing herb in Korea. 3. Soonchang malted pepper catchup is one of outstanding traditional foods which our ancestor have processed with red pepper. Peru is the place of origin, where they have cultivated pepper from 1st century. It is conceivable that pepper was transmitted from Europe to korea late in 16th century, and the first report on existence of pepper in korea was written in 1613. Therefore, it seems that malted red pepper catchup was processed 30 or 40 years later.

• 서비스연구
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• 제8권1호
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• pp.73-87
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• 2018

세계 각국은 서비스 경제화를 위한 각종 육성 정책을 마련하고 있다. 최근 4차 산업혁명이 가속화되면서 서비스산업의 역할에 관심이 높아지고 있다. 한국의 서비스산업은 고용, 부가가치, 생산성 측면에서 OECD 국가 중 하위권에 속하며 새로운 발전 전략을 모색할 시점이다. 우리 정부는 고용과 경제 활력을 도모하기 위하여 서비스 경제 발전 전략을 수립하고 있다. 하지만 4차 산업혁명 시대에서 서비스산업은 제조업과 융합되어 발전되어야 한다는 점에서 그 중요성이 높다. 본 연구에서는 문헌고찰을 통하여 중앙정부, 지방정부, 그리고 세계 각국이 추진하고 있는 4차 산업혁명과 관련된 주요 서비스산업 정책을 고찰한다. 그리고 4차 산업혁명에 대비한 7대 서비스산업 및 핵심 기술을 빅데이터 분석하고 그 관심도를 도출한다.

• International Journal of Advanced Culture Technology
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• 제8권4호
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• pp.82-88
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• 2020

With the development of medical care in the 21st century and the rapid development of the 4th industry, electronic devices and household goods taking into account the physical and mental aging of the silver generation have been developed, and apps related to health and health are generally developed and operated. The apps currently used by the silver generation are a form that provides information on diseases by focusing on prevention rather than treatment, such as safety management apps for the elderly living alone and methods for preventing diseases. There are not many apps that provide information on foods that have a direct effect and nutrients in that food, and research on apps that can obtain information about individual foods is insufficient. In this paper, we propose an app that analyzes food factors and provides self-medication for health promotion of the silver generation. This app allows the silver generation to conveniently and easily obtain information such as nutrients, calories, and efficacy of food they need. In addition, this app collects/categorizes healthy food information through a textom solution-based crawling agent, and stores highly relevant words in a data resource. In addition, wide deep learning was applied to enable self-medication recommendations for food. When this technique is applied, the most appropriate healthy food is suggested to people with similar eating patterns and tastes in the same age group, and users can receive recommendations on customized healthy foods that they need before eating. This made it possible to obtain convenient healthy food information through a customized interface for the elderly through a smartphone.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2013년도 추계학술대회
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• pp.243-246
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• 2013

최근 우리나라 4세대 이동통신은 누구와도 고속 멀티미디어 통신 서비스가 지원하고 있다. 애플의 아이폰이 출시되면서 스마트폰에 대한 관심이 폭발적으로 증가하고 스마트폰을 활용하는 인터넷 기반 서비스가 활성화되고 있다. 스마트폰 이용자는 경제활동 인구의 대부분이 사용하고 있으며 초기형성단계를 지나 포화상태에 도달한 것으로 전문가들은 내다보고 있다. 이동통신 서비스는 1989년 아날로그 음성통화 서비스를 시작하였다. 그 후 1990년대 중반 문자메시지 전송과 디지털 음성통화 서비스가 가능한 2세대 방식이었고, 그리고 2000년 이후 저속의 데이터 서비스와 저품질의 동영상을 주고받을 수 있는 3세대 이동통신이 발전하게 되었다. 국내 이동통신은 2011년 7월 고속의 데이터 전송 속도를 제공할 수 있는 4세대 이동통신 표준방식인 LTE (long term evolution) 서비스를 상용화 하였고 현재 지속적으로 가입자가 증가하고 있다. 그런데 이러한 통신기술의 변화는 스마트폰 이용자들에게 경제적 부담을 안겨주고 있다. 따라서 본 연구의 목적은 이동통신 산업의 통신기술의 변화에 따른 통신요금 추이를 알아보고자 하였다.