• Title/Summary/Keyword: $14-3-3{\theta}$

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The Crystal Structure of Metoclopramide

  • Shin, Whan-chul;Chang, Tai-Sik;Koo, Chung-Hoe
    • Bulletin of the Korean Chemical Society
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    • v.4 no.3
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    • pp.123-127
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    • 1983
  • The crystal structure of metoclopramide, $C_14H_22ClN_3O_2$, has been determined by X-ray diffraction techniques using diffractometer data obtained by the ${\omega}-2{\theta}$ scan technique with Mo $K\alpha$ radiation from a crystal with space group symmetry $P{\overline{1}}$ and unit cell parameters a = 7.500(1), b = 8.707(2), c = 13.292(2) ${\AA}$; ${\alpha}$ = 101.70(2), ${\beta}$ = 81.20(2), and ${\gamma}$ = $114.90(l)^{\circ}$. The sructure was solved by direct methods and refined by full-matrix least-squares to a final R = 0.055 for the 1524 observed reflections. The bent overall-conformation of the molecule seems to be determined mainly by the bifurcated intramolecular hydrogen bond from the amide nitrogen atom to the methoxy oxygen and the amine nitrogen atoms. The crystal packing consists of the hydrogen bonds, ${\pi}-{\pi}$ interaction and hydrophobic interaction.

EEG 16 channel variations between the non-stimulation and the moxibustion stimulated subjects for CV4, CV8, and CV12 acupuncture points (중완, 신궐 및 관원 경혈의 뜸 자극과 무 자극 대상군의 16채널 뇌파 변화에 관한 연구)

  • Yoon, Dong-Eop;Song, Hong-Bok
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.14 no.12
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    • pp.2755-2760
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    • 2010
  • The moxibustion therapy of orient medical is well known. Moxibustion method is used to burning moxibustion. The variation factors of the moxibustion stimulation for body can be applied to the electronic moxibustion method. This study is to analyze and examine the electroencephalogram(EEG) variations for moxibustion stimulation. In experiment, we divided six healthy male subjects into two same sized groups : with and without stimuli. The given stimuli are the moxibustion for CV4(Kwan-Won), CV8(Shin-Guel), and CV12(Jung-wan) acupuncture points. We have analyzed the power spectrum for ${\alpha}$, ${\beta}$, ${\delta}$, ${\Theta}$ waves and the average EEG variation level and each channels variation level of EEG. The result was that the moxibustion stimulation decreased the EEG levels of parietal lobe(ch 2, 3, 6, 7) according to the somatosensory system. And the apparent different points are that mild-heat($42{\sim}44^{\circ}C$) stimulation generating ${\alpha}$-wave is increased and ${\beta}$-wave is decreased, also slight-hot($45{\sim}48^{\circ}C$) stimulation made ${\alpha}$-wave decrease and ${\beta}$-wave increase for occipital lobe(ch 4,8) on the simulation group.

MULTIPLE SOLUTIONS IN NATURAL CONVECTION BETWEEN TWO HORIZONTAL PLATES WITH SMALL MAGNITUDE NON-UNIFORM TEMPERATURE IN THE UPPER PLATE (위 평판이 작은 불균일 온도를 갖는 두 수평 평판 사이의 자연 대류에서의 다중해)

  • Yoo, Joo-Sik
    • Journal of computational fluids engineering
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    • v.21 no.3
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    • pp.64-70
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    • 2016
  • Multiple solutions in natural convection of water with Pr=7 between two horizontal plates with small magnitude non-uniform temperature distribution in the upper plate is numerically investigated. The dimensionless temperature of upper plate is ${\theta}={\epsilon}sinkx$. Two upright cells are formed over one wave length in the conduction-dominated regime of small Rayleigh number. However, multicellular convection occurs above a critical Rayleigh number for small wave number. When k = 1.5, dual solutions are found and a transition of $6{\rightarrow}4$ eddy flow occurs with decrease of Rayleigh number. When k = 0.75, two, three, four and five multiple solutions are observed. Transitions of $14{\rightarrow}12$, $12{\rightarrow}10$, $10{\rightarrow}8$ and $6{\rightarrow}8$ eddy flow occur with decrease of Rayleigh number.

A Study over Catalytic Behavior Octane Enhancer, TAME Synthesis with Ion Exchange Resin Catalysts (이온교환수지 촉매를 이용한 옥탄가 향상제인 TAME 합성반응의 연구)

  • Park, Jin-Hwa
    • Applied Chemistry for Engineering
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    • v.7 no.5
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    • pp.832-842
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    • 1996
  • TAME synthesis was studied in a fixed bed reactor with 3 different types of exchanged resins i.e, Amberlyst-15, Amberlyst-15(wet) and Amberlyst XN-1010. Amberlyst-15 has highest activity, presumably due to the higher reaction participation of the inner active sites of gel shape microparticular resin structure. The optimum reaction conditions for TAME synthesis were found as follows ; reaction temperature of $135^{\circ}C$, molar ratio(MeOH/I.A.A) of 1.0~4.0 and W/F of 2.0~4.0 gr.-cat. hr/gr.-mole. The cross-linking bond of styrene divinyl benzene was observed at $2{\theta}=20$ in XRD pattern. The DSC analysis showed that the thermal stability was in order of Amberlyst-15>Amberlyst-15(wet)>Amberlyst XN-1010. The apparent activation energies of TAME synthesis reaction with Amberlyst-15, Amberlyst-15(wet) and Amberlyst XN-1010 were 12.36, 12.46 and 14.72 kcal/mole, respectively.

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An Investigation of Dispersion Behavior of Y2O3 Ceramic Particles in Hypo, Eutectic and Hyper Binary Al-Cu Cast Alloys (아공정, 공정, 과공정 조성의 Al-Cu 주조합금에서의 Y2O3 분말의 분산 거동에 대한 연구)

  • Park, J.J.;Kim, G.H.;Hong, S.M.;Lee, S.H.;Lee, M.K.;Rhee, C.K.
    • Journal of Powder Materials
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    • v.14 no.2 s.61
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    • pp.123-126
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    • 2007
  • In this work, the dispersion behavior of $Y_2O_3$ particles in binary aluminum (Al)-copper (Cu) cast alloy was investigated with respect to Cu contents of 20 (hypoeutertic), 33 (eutectic) and 40 (hypereutectic) wt.%. In cases of hypo and hypereutectic compositions, SEM images revealed that the primary Al and ${\theta}$ phases were grown up at the beginning, respectively, and thereafter the eutectic phase was solidified. In addition, it was found that some of $Y_2O_3$ particles can be dispersed into the primary Al phase, but none of them are is observed inside the primary 6 phase. This different dispersion behavior of $Y_2O_3$ particles is probably due to the difference in the val- ues of specific gravity between $Y_2O_3$ particles and primary phases. At eutectic composition, $Y_2O_3$ particles were well dispersed in the matrix since there is few primary phases acting as an impediment site for particle dispersion during solidification. Based on the experimental results, it is concluded that $Y_2O_3$ particles are mostly dispersed into the eutectic phase in binary Al-Cu alloy system.

Expression of Alpha-Amylase Gene from Bacillus licheniformis in Lactobacillus brevis 2.14

  • Lee, Kang-Wook;Park, Ji-Yeong;Kim, Gyoung-Min;Kwon, Gun-Hee;Park, Jae-Yong;Lee, Mee-Ryung;Chun, Ji-Yeon;Kim, Jeong-Hwan
    • Preventive Nutrition and Food Science
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    • v.13 no.3
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    • pp.190-195
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    • 2008
  • The $\alpha$-amylase gene, amyL, from Bacillus licheniformis was expressed in Lactobacillus brevis 2.14 and Escherichia coli $DH5{\alpha}$ using two different shuttle vectors, pCW4 and pSJE. E. coli transformants (TFs) harboring either $pCW4T{\alpha}$ or $pSJET{\alpha}$ produced active $\alpha$-amylase but L. brevis TFs did not, as determined by enzyme assays and zymography. But amyL transcripts were synthesized in L. brevis TFs. In terms of plasmid stability, pSJE, a theta-type replicon, was more stable than pCW4, an RCR (rolling circle replication) plasmid, in L. brevis without antibiotic selection.

Changes of the Prefrontal EEG(Electroencephalogram) Activities according to the Repetition of Audio-Visual Learning (시청각 학습의 반복 수행에 따른 전두부의 뇌파 활성도 변화)

  • Kim, Yong-Jin;Chang, Nam-Kee
    • Journal of The Korean Association For Science Education
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    • v.21 no.3
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    • pp.516-528
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    • 2001
  • In the educational study, the measure of EEG(brain waves) can be useful method to study the functioning state of brain during learning behaviour. This study investigated the changes of neuronal response according to four times repetition of audio-visual learning. EEG data at the prefrontal$(Fp_{1},Fp_{2})$ were obtained from twenty subjects at the 8th grade, and analysed quantitatively using FFT(fast Fourier transform) program. The results were as follows: 1) In the first audio-visual learning, the activities of $\beta_{2}(20-30Hz)$ and $\beta_{1}(14-19Hz)$ waves increased highly, but the activities of $\theta(4-7Hz)$ and $\alpha$ (8-13Hz) waves decreased compared with the base lines. 2). According to the repetitive audio-visual learning, the activities of $\beta_{2}$ and $\beta_{1}$ waves decreased gradually after the 1st repetitive learning. And, the activity of $\beta_{2}$ wave had the higher change than that of $\beta_{1}$ wave. 3). The activity of $\alpha$ wave decreased smoothly according to the repetitive audio-visual learning, and the activity of $\theta$ wave decreased radically after twice repetitive learning. 4). $\beta$ and $\theta$ waves together showed high activities in the 2nd audio-visual learning(once repetition), and the learning achievement increased highly after the 2nd learning. 5). The right prefrontal$(Fp_{2})$ showed higher activation than the left$(Fp_{1})$ in the first audio-visual learning. However, there were not significant differences between the right and the left prefrontal EEG activities in the repetitive audio-visual learning. Based on these findings, we can conclude that the habituation of neuronal response shows up in the repetitive audio-visual learning and brain hemisphericity can be changed by learning experiences. In addition, it is suggested once repetition of audio-visual learning be effective on the improvement of the learning achievement and on the activation of the brain function.

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Structure of Cholesteryl Pentyl Carbonate (Cholesteryl Pentyl Carbonate의 결정 및 분자구조)

  • Seo, Hye Ran;Park, Yeong Ja;B. M. Craven
    • Journal of the Korean Chemical Society
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    • v.34 no.1
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    • pp.29-36
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    • 1990
  • Cholesteryl pentyl carbonate $(C_{33}H_{56}O_3)$ is monoclinic, space group P21, with a = 12.484(3), b = 9.043(3), c = 14.053(3)$\AA$, ${\beta} = 94.12(2)^{\circ}$ and z = 2. The intensity data were measured for the 2969 reflections within sin $\theta/\lambda = 0.52 {\AA}^{-1}$, using an automatic four--circle diffractometer and graphite monochromated Mo-K$\alpha$ radiation. The atomic coordinates from cholesteryl octanoate were used in an initial trial structure and the structure was refined by full-matrix least squares methods. The final R-factor was 0.12 for 1164 observed reflections. The pentyl group has shortened bond lengths due to the high thermal vibrations in this region. Adjacent molecules are related by $2_1$ screw axis so that they are arranged in an antiparallel array, corresponding to the Monolayer Type II packing mode. There are close packings of cholesteryl groups within the monolayers. This packing type is similar to those of cholesteryl hexanoate, octanoate, hexyl carbonate and oleate.

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Studies on the Rice Yield Decreased by Ground Water Irrigation and Its Preventive Methods (지하수 관개에 의한 수도의 멸준양상과 그 방지책에 관한 연구)

  • 한욱동
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.16 no.1
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    • pp.3225-3262
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    • 1974
  • The purposes of this thesis are to clarify experimentally the variation of ground water temperature in tube wells during the irrigation period of paddy rice, and the effect of ground water irrigation on the growth, grain yield and yield components of the rice plant, and, furthermore, when and why the plant is most liable to be damaged by ground water, and also to find out the effective ground water irrigation methods. The results obtained in this experiment are as follows; 1. The temperature of ground water in tube wells varies according to the location, year, and the depth of the well. The average temperatures of ground water in a tubewells, 6.3m, 8.0m deep are $14.5^{\circ}C$ and $13.1^{\circ}C$, respercively, during the irrigation period of paddy rice (From the middle of June to the end of September). In the former the temperature rises continuously from $12.3^{\circ}C$ to 16.4$^{\circ}C$ and in the latter from $12.4^{\circ}C$ to $13.8^{\circ}C$ during the same period. These temperatures are approximately the same value as the estimated temperatures. The temperature difference between the ground water and the surface water is approximately $11^{\circ}C$. 2. The results obtained from the analysis of the water quality of the "Seoho" reservoir and that of water from the tube well show that the pH values of the ground water and the surface water are 6.35 and 6.00, respectively, and inorganic components such as N, PO4, Na, Cl, SiO2 and Ca are contained more in the ground water than in the surface water while K, SO4, Fe and Mg are contained less in the ground water. 3. The response of growth, yield and yield components of paddy rice to ground water irrigation are as follows; (l) Using ground water irrigation during the watered rice nursery period(seeding date: 30 April, 1970), the chracteristics of a young rice plant, such as plant height, number of leaves, and number of tillers are inferior to those of young rice plants irrigated with surface water during the same period. (2) In cases where ground water and surface water are supplied separately by the gravity flow method, it is found that ground water irrigation to the rice plant delays the stage at which there is a maximum increase in the number of tillers by 6 days. (3) At the tillering stage of rice plant just after transplanting, the effect of ground water irrigation on the increase in the number of tillers is better, compared with the method of supplying surface water throughout the whole irrigation period. Conversely, the number of tillers is decreased by ground water irrigation at the reproductive stage. Plant height is extremely restrained by ground water irrigation. (4) Heading date is clearly delayed by the ground water irrigation when it is practised during the growth stages or at the reproductive stage only. (5) The heading date of rice plants is slightly delayed by irrigation with the gravity flow method as compared with the standing water method. (6) The response of yield and of yield components of rice to ground water irrigation are as follows: \circled1 When ground water irrigation is practised during the growth stages and the reproductive stage, the culm length of the rice plant is reduced by 11 percent and 8 percent, respectively, when compared with the surface water irrigation used throughout all the growth stages. \circled2 Panicle length is found to be the longest on the test plot in which ground water irrigation is practised at the tillering stage. A similar tendency as that seen in the culm length is observed on other test plots. \circled3 The number of panicles is found to be the least on the plot in which ground water irrigation is practised by the gravity flow method throughout all the growth stages of the rice plant. No significant difference is found between the other plots. \circled4 The number of spikelets per panicle at the various stages of rice growth at which_ surface or ground water is supplied by gravity flow method are as follows; surface water at all growth stages‥‥‥‥‥ 98.5. Ground water at all growth stages‥‥‥‥‥‥62.2 Ground water at the tillering stage‥‥‥‥‥ 82.6. Ground water at the reproductive stage ‥‥‥‥‥ 74.1. \circled5 Ripening percentage is about 70 percent on the test plot in which ground water irrigation is practised during all the growth stages and at the tillering stage only. However, when ground water irrigation is practised, at the reproductive stage, the ripening percentage is reduced to 50 percent. This means that 20 percent reduction in the ripening percentage by using ground water irrigation at the reproductive stage. \circled6 The weight of 1,000 kernels is found to show a similar tendency as in the case of ripening percentage i. e. the ground water irrigation during all the growth stages and at the reproductive stage results in a decreased weight of the 1,000 kernels. \circled7 The yield of brown rice from the various treatments are as follows; Gravity flow; Surface water at all growth stages‥‥‥‥‥‥514kg/10a. Ground water at all growth stages‥‥‥‥‥‥428kg/10a. Ground water at the reproductive stage‥‥‥‥‥‥430kg/10a. Standing water; Surface water at all growh stages‥‥‥‥‥‥556kg/10a. Ground water at all growth stages‥‥‥‥‥‥441kg/10a. Ground water at the reproductive stage‥‥‥‥‥‥450kg/10a. The above figures show that ground water irrigation by the gravity flow and by the standing water method during all the growth stages resulted in an 18 percent and a 21 percent decrease in the yield of brown rice, respectively, when compared with surface water irrigation. Also ground water irrigation by gravity flow and by standing water resulted in respective decreases in yield of 16 percent and 19 percent, compared with the surface irrigation method. 4. Results obtained from the experiments on the improvement of ground water irrigation efficiency to paddy rice are as follows; (1) When the standing water irrigation with surface water is practised, the daily average water temperature in a paddy field is 25.2$^{\circ}C$, but, when the gravity flow method is practised with the same irrigation water, the daily average water temperature is 24.5$^{\circ}C$. This means that the former is 0.7$^{\circ}C$ higher than the latter. On the other hand, when ground water is used, the daily water temperatures in a paddy field are respectively 21.$0^{\circ}C$ and 19.3$^{\circ}C$ by practising standing water and the gravity flow method. It can be seen that the former is approximately 1.$0^{\circ}C$ higher than the latter. (2) When the non-water-logged cultivation is practised, the yield of brown rice is 516.3kg/10a, while the yield of brown rice from ground water irrigation plot throughout the whole irrigation period and surface water irrigation plot are 446.3kg/10a and 556.4kg/10a, respectivelely. This means that there is no significant difference in yields between surface water irrigation practice and non-water-logged cultivation, and also means that non-water-logged cultivation results in a 12.6 percent increase in yield compared with the yield from the ground water irrigation plot. (3) The black and white coloring on the inside surface of the water warming ponds has no substantial effect on the temperature of the water. The average daily water temperatures of the various water warming ponds, having different depths, are expressed as Y=aX+b, while the daily average water temperatures at various depths in a water warming pond are expressed as Y=a(b)x (where Y: the daily average water temperature, a,b: constants depending on the type of water warming pond, X; water depth). As the depth of water warning pond is increased, the diurnal difference of the highest and the lowest water temperature is decreased, and also, the time at which the highest water temperature occurs, is delayed. (4) The degree of warming by using a polyethylene tube, 100m in length and 10cm in diameter, is 4~9$^{\circ}C$. Heat exchange rate of a polyethylene tube is 1.5 times higher than that or a water warming channel. The following equation expresses the water warming mechanism of a polyethylene tube where distance from the tube inlet, time in day and several climatic factors are given: {{{{ theta omega (dwt)= { a}_{0 } (1-e- { x} over { PHI v })+ { 2} atop { SUM from { { n}=1} { { a}_{n } } over { SQRT { 1+ {( n omega PHI) }^{2 } } } } LEFT { sin(n omega t+ { b}_{n }+ { tan}^{-1 }n omega PHI )-e- { x} over { PHI v }sin(n omega LEFT ( t- { x} over {v } RIGHT ) + { b}_{n }+ { tan}^{-1 }n omega PHI ) RIGHT } +e- { x} over { PHI v } theta i}}}}{{{{ { theta }_{$\infty$ }(t)= { { alpha theta }_{a }+ { theta }_{ w'} +(S- { B}_{s } ) { U}_{w } } over { beta } , PHI = { { cpDU}_{ omega } } over {4 beta } }}}} where $\theta$$\omega$; discharged water temperature($^{\circ}C$) $\theta$a; air temperature ($^{\circ}C$) $\theta$$\omega$';ponded water temperature($^{\circ}C$) s ; net solar radiation(ly/min) t ; time(tadian) x; tube length(cm) D; diameter(cm) ao,an,bn;constants determined from $\theta$$\omega$(t) varitation. cp; heat capacity of water(cal/$^{\circ}C$ ㎥) U,Ua; overall heat transfer coefficient(cal/$^{\circ}C$ $\textrm{cm}^2$ min-1) $\omega$;1 velocity of water in a polyethylene tube(cm/min) Bs ; heat exchange rate between water and soil(ly/min)

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A Study on The Improving Effects of the Bearing Capacity of Very Soft Ground by Restricting Conditions of Reinforcement (보강재의 구속조건에 따른 초연약지반의 지지력개선효과에 관한 연구)

  • Ham, Tae-Gew;Cho, Sam-Deok;Yang, Kee-Sok;Yoo, Seung-Kyong
    • Journal of the Korean Geosynthetics Society
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    • v.7 no.3
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    • pp.41-49
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    • 2008
  • This study was carried out the model experiment in laboratory to evaluate the bearing capacity improvement of soft ground as altered constraint condition of reinforcements according to geotextile, georid, steel bar. As a results, the value of BCR was increased linearly as improvement of the stiffness of reinforcements, and the factor governed the increasement of BCR was the increasement of frictions between reinforcement and clay as far as the constrain conditions increased until T=85.6kg. Moreover, An angle of inclination, ${\theta}$, between reinforcement and horizontal surface was distributed from $38^{\circ}$ to $50^{\circ}$ for Geotextile, from $45^{\circ}$ to $50^{\circ}$ for Geogrid and from $14^{\circ}$ to $16^{\circ}$ for steel bar. A radius of heaving, r, of clay ground by vertical weight at side was distributed from 0.6m to 0.7m for Geotextile, from 0.5m to 0.8m for Geogrid, and from 2.4m to 3.0m for steel bar. In case of steel bar, r was 4 times that of Geotextile.

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