• 제목/요약/키워드: ${\tau}_m$

검색결과 359건 처리시간 0.019초

Effects of Epidermal Growth Factor on the Apoptosis and Implantation Related Genes in Bovine Embryos Developing in vitro

  • Park, Sae-Young;Tae, Jin-Cheol;Kim, Eun-Young;Park, Se-Pill;Lim, Jin-Ho;Kim, Nam-Hyung
    • 한국발생생물학회:학술대회논문집
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    • 한국발생생물학회 2003년도 제3회 국제심포지움 및 학술대회
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    • pp.114-114
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    • 2003
  • Epidermal growth factor (EGF) induces well-documented mitogenic and differentiating effects on murine and bovine preimplantation embryos. However, the effects of EGF on apoptosis and implantation-related gene expression in bovine embryos developing in vitro have not been evaluated. The objective of this study was to determine the effects of exogenous EGF in the presence and absence of BSA on the preimplantation development of bovine embryos. In addition, we measured cell number, apoptosis, and expression of apoptosis and implantation-related genes of the blastocysts that developed in these culture conditions. In vitro produced bovine embryos were randomly cultured in the same medium containing 0 or 10 ng/ml EGF in the presence and absence of 0.8% BSA. More 2-cell embryos developed into blastocysts at day 7 when BSA was present than when BSA was absent. The addition of 10 ng/$m\ell$ EGF into the medium did not significantly increase the developmental rate and the cell numbers per blastocyst. However, addition of EGF in the presence of 0.8% BSA significantly reduced the degree of apoptosis in the blastocysts (P<0.01). To investigate whether EGF modulates mRNA expression of apoptosis-related genes, mRNA was prepared from single blastocysts and each preparation was subjected to RT-PCR for Bcl-2 and Bax transcripts. EGF did not alter the relative abundance of Bax gene expression in the presence of BSA, but increase Bcl-2 (P<0.01) The relative abundance of Interferon tau expression was increased by EGF treatment in the presence of BSA. These results suggest that EGF and BSA synergistically enhance Bcl-2 and interferone tau gene expression, which may result in a net increase in viability in bovine embryos.

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Synthesis, Structure and Magnetic Properties of Mn12 Single Molecule Magnet Containing 4-(Methylthio)benzoate as Peripheral Ligands

  • Lim, Jin-Mook;Do, Young-Kyu;Kim, Jin-Kwon
    • Bulletin of the Korean Chemical Society
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    • 제26권7호
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    • pp.1065-1070
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    • 2005
  • $[Mn_{12}O_{12}(O_2CPh-4-SMe)_{16}(H_2O)_4]{\cdot}7CH_2Cl_2$ (1), a new single-molecule magnet complex has been successfully synthesized by substitution of acetate ligand of Mn12ac with 4-(methylthio)benzoic acid. Complex 1 crystallizes into triclinic P$\overline{1}$ with a = 18.321(3) $\AA$, b = 19.011(3) $\AA$, c = 27.230(4) $\AA$, $\alpha$ = 86.973(3)$^{\circ}$, $\beta$ = 76.919(3)$^{\circ}$, $\gamma$ = 87.613(3)$^{\circ}$, and Z = 2. In complex 1, one Mn(III) ion has an abnormal Jahn-Teller elongation axis oriented at an oxide ion. Complex 1 has two out-of-phase ac susceptibility peaks in the 2-4 K and 4-7 K regions. Effective anisotropy energy barrier and pre-exponential factor are $U_{eff}$ = 45.95 K, 1/$\tau$0 = 8.6 ${\times}\;10^9s^{-1}\;for\;{\chi}_M$'' peaks in the lower temperature region and $U_{eff}$ = 59.45 K, 1/$\tau_0$ = 2.2 ${\times}\;10^8\;s^{-1}$ for $\chi_M$'' peaks in the higher temperature region. The parameters of S = 10, g = 1.87, D = -0.40 $cm^{-1}$, and E = 0.00034 $cm^{-1}$ were obtained from the M/N${\mu}_B$ vs. H/T plot of complex 1.

저온소결 (Zn0.8Mg0.2)TiO3 세라믹의 마이크로파 유전특성에 관한 연구 (A Study on Microwave Dielectric Properties of Low-Temperature Sintered (Zn0.8Mg0.2)TiO3 Ceramics)

  • 방재철;심우성
    • 한국전기전자재료학회논문지
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    • 제16권7호
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    • pp.604-610
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    • 2003
  • The effects of sintering additives such as B $i_2$ $O_3$ and $V_2$ $O_{5}$ on the microwave dielectric and sintering properties of (Z $n_1$$_{-xM}$ $g_{x}$)Ti $O_3$ system were investigated. Highly dense samples were obtained for (Z $n_{0.8}$M $g_{0.2}$)Ti $O_3$ at the sintering temperature range of 870~90$0^{\circ}C$ with B $i_2$ $O_3$ and $V_2$ $O_{5}$ additions of 〈1 wt.%, respectively. The microwave dielectric properties of (Z $n_{0.8}$M $g_{0.2}$)Ti $O_3$ with 0.45 wt.%B $i_2$ $O_3$ and 0.55 wt.% $V_2$ $O_{5}$ sintered at 90$0^{\circ}C$ were as follows : Q$\times$ $f_{o}$ = 50,800 GHz, $\varepsilon$$_{r}$ = 22, and $\tau$$_{f}$ = -53 ppm/$^{\circ}C$. In order to improve temperature coefficient of resonant frequency, Ti $O_2$ was added to the above system. The optimum amount of Ti $O_2$ was 15 moi.% when sintered at 87$0^{\circ}C$, at which we could obtain following results: Q$\times$ $f_{o}$ = 32,800 GHz, $\varepsilon$$_{r}$ = 26, and$\tau$$_{f}$ = 0 ppm/$^{\circ}C$.EX>.EX>.EX>.EX>.EX>.EX>.EX>.

TANGENTIAL REPRESENTATIONS AT ISOLATED FIXED POINTS OF ODD-DIMENSIONAL G-MANIFOLDS

  • Komiya, Katsuhiro
    • 대한수학회보
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    • 제45권1호
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    • pp.33-37
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    • 2008
  • Let G be a compact abelian Lie group, and M an odd-dimensional closed smooth G-manifold. If the fixed point set $M^G\neq\emptyset$ and dim $M^G=0$, then G has a subgroup H with $G/H{\cong}\mathbb{Z}_2$, the cyclic group of order 2. The tangential representation $\tau_x$(M) of G at $x{\in}M^G$ is also regarded as a representation of H by restricted action. We show that the number of fixed points is even, and that the tangential representations at fixed points are pairwise isomorphic as representations of H.

지상관측장비를 이용하여 관측한 봄철 황사의 연직분포와 광학적 특성 분석 (Analysis of Vertical Profiles and Optical Characteristics of the Asian Dust Using Ground-based Measurements)

  • 이병일;윤순창;김윤재
    • 대기
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    • 제18권4호
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    • pp.287-297
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    • 2008
  • The vertical profiles and optical properties of Asian dust are investigated using ground-based measurements from 1998 to 2002. Vertical profiles of aerosol extinction coefficient are evaluated using MPL (Micro Pulse Lidar) data. Optical parameters such as aerosol optical thickness ($\tau$), ${\AA}ngstr\ddot{o}m$ exponent ($\alpha$), single scattering albedo ($\omega$), refractive index, and volume size distribution are analyzed with sun/sky radiometer data for the same period. We can separate aerosol vertical profiles into three categories. First category named as 'Asian dust case', which aerosol extinction coefficient is larger than $0.15km^{-1}$ and dust layer exists from surface up to 3-4km. Second category named as 'Elevated aerosol case', which aerosol layer exists between 2 and 6km with 1-2.5km thickness, and extinction coefficient is smaller than $0.15km^{-1}$. Third category named as 'Clear sky case', which aerosol extinction coefficient appears smaller than $0.15km^{-1}$. and shows that diurnal variation of background aerosol in urban area. While optical parameters for first category indicate that $\tau$ and $\alpha$ are $0.63{\pm}0.14$, $0.48{\pm}0.19$, respectively. Also, aerosol volume concentration is increased for range of 1 and $4{\mu}m$, in coarse mode. Optical parameters for second category can be separated into two different types. Optical properties of first type are very close to Asian dust cases. Also, dust reports of source region and backward trajectory analyses assure that these type is much related with Asian dust event. However, optical properties of the other type are similar to those of urban aerosol. For clear sky case, $\tau$ is relatively smaller and $\alpha$ is larger compare with other cases. Each case shows distinct characteristics in aerosol optical parameters.

비정질 $Fe_{83}B_9Nb_7Cu_1$의 M$\ (Distributions of Hyperfine Parameters in Amorphous $Fe_{83}B_9Nb_7Cu_1$ Alloys)

  • 윤성현;김성백;김철성
    • 한국자기학회지
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    • 제9권6호
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    • pp.271-277
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    • 1999
  • M ssbauer 분광법을 이용하여 비정질합금 Fe83B9Nb7Cu1의 자기적 성질을 연구하였다. 개선된 Vincze의 방법을 적용하여 각 온도에서 초미세자기장, 이성질체 이동치, 그리고 quadrupole line broadening의 분포함수들을 얻었고 큐리온도는 393K, Hhf(0)는 231kOe로 산출되었다. 환산된 평균 초미세 자기장(reduced average hyperfine field)의 온도 변화는 S=1 자기화 곡선에 비해 급히 감소하는 양상을 보였고 이를 설명하기 위해 Handrich의 분자장 이론에서 교환 상호 작용의 척도인 에 =0.75-0.64(T/Tc)+0.47(T/Tc)2의 온도 의존성을 도입하였다. 평균 초미세 자기장(Hhf(T))은 저온에서 스핀파 여기에 의한 공식 Hhf(T)=Hhf(0)[1-0.44(T/Tc)3/2-0.28(T/Tc)5/2- ]으로 분석하였고, 큐리온도 부근에서는 1.00[1-T/Tc]0.39의 관계를 갖는 것으로 나타났다. 초미세 자기장 분포곡선의 선폭은 13K에서 102kOe (3.29 mm/s)였으며, 오도가 증가함에 따라 감소했다. 큐리온도 이상에서 평균 quadrupole splitting값은 0.43 mm/s였으며 quadrupole 이동치 분포에 의한 선폭 증가는 13K에서 0.1 mm/s, 320K에서는 0.072 mm/s 정도로 초미세 자기장 분포나 quadrupole line broadening에 의한 선폭 증가보다 작았다. 이성질체 이동치의 온도 변화에 Debye 모형을 적용하여 Debye 온도를 D=424K로 산출하였다.

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소 형질전환 복제란의 유전자 이상발현 규명 (Differential Gene Expression in the Bovine Transgenic Nuclear Trasnsfer Embryos)

  • 조종기;송봉석;용환율;이두수;구덕본;이경광;신상태
    • 한국임상수의학회지
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    • 제24권3호
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    • pp.295-299
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    • 2007
  • 체세포 핵이식을 통한 형질전환 소를 생산 시 초기 수정란 발육 시 발생하는 주요 유전자의 이상 발현을 규명을 목적으로 본 연구를 수행하였다. 형질전환 복제수정란의 낮은 발육능의 원인을 규명하기 위해 하기 위하여 단위 발생란, 체외수정란 및 형질전환 복제수정란에서 초기 배 발육에 중요한 유전자인 IFN-t, Oct4 및 Fgf4유전자의 발현량을 비교 분석하였다. RNA는 각각 10개 수정란에서 추출한 후 reverse-transcription하여 first cDNA를 합성하고 이를 가지고 실시간 중합효수 연쇄반응을 실시하였다. IFN-t유전자의 발현은 형질전환 복제란에서 유의적으로 높게 나왔다 (P<0.05).그러나 Oct4 및 Fgf4 유전자의 경우 형질전환 복제란에서 체외수정란에 비해 유의적으로 낮게 나옴을 확인하였다. 이상의 결과로, 형질전환 복제수정란의 낮은 발육능이 원인이 발육에 중요한 유전자의 이상 발현에 기인된다고 사료된다.

Predicting Scour at Bridge Piers

  • Briaud, Jean-Louis
    • 한국지반공학회:학술대회논문집
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    • 한국지반공학회 1999년도 봄 학술발표회 논문집
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    • pp.3-46
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    • 1999
  • A new method called SRICOS is proposed to predict the scour depth z versus time t around a cylindrical bridge pier of diameter D founded in clay. The steps involved are ; 1. taking samples at the bridge pier site, 2. testing them in an Erosion Function Apparatus called the EFA to obtain the scour rate z versus the hydraulic shear stress applied $\tau$, 3. predicting the maximum shear stress r max which will be induced around the pier by the water flowing at ν Ο before the scour hole starts to develop, 4. using the measured z versus r curve to obtain the initial scour rate zi corresponding to r max , 5. predicting the maximum depth of scour zmax for the pier, 6. using zi and zmarx to develop the hyperbolic function describing the scour depth z versus time t curve, and 7. reading the z vs. t curve at a time corresponding to the duration of the flood to find the scour depth which will develop around the pier. A new apparatus is developed to measure the z vs t curve of step 2, a series of advanced numerical simulations are performed to develop an equation for the $\tau$ max value of step 3, and a series of flume tests are performed to develop an equation for the zmax value of step 5. The method is evaluated by comparing predictions and measurements in 42 flume experiments.

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스크램제트 연료로써 JP-7 의 점화 특성 (Ignition Characteristics of JP-7 as a Scramjet Fuel)

  • 최정열
    • 한국추진공학회:학술대회논문집
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    • 한국추진공학회 2005년도 제24회 춘계학술대회논문집
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    • pp.377-380
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    • 2005
  • 산소 및 공기와 반응시 크랙된 JP-7 연료의 점화 특성에 관한 연구를 넓은 범위의 압력(1-20atm)과 온도(1200-2000K), 당량비(0.5-1.5)에 대해서 수행하였다. Chemkin-II Package와 최소 자승법을 이용하여 $\tau=Aexp(E/RT)[F]^{a}[O_2]^{b}$형태로 점화 지연시간을 계산하고 각 변수 사이의 상호관계를 검증하였다. 크랙된 JP-7 연료에서 $C_3$ 탄화수소 계열 성분의 영향을 두 가지 다른 크랙된 JP-7연료의 조성에 대하여 점화지연 시간을 비교하였으며, 액체 JP-7 연료의 점화 지연 시간과도 비교하여 보았다.

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인산 에스테르 셀룰로오스 ER 유체의 전기유변학적 특성에 대한 계면활성제의 영향 (The Effect of Surfactant on the Electrorheological Properties of Phosphoric Ester Cellulose ER Fluids)

  • 안병길;최웅수;권오관
    • Tribology and Lubricants
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    • 제15권3호
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    • pp.240-247
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    • 1999
  • The electrorheological (ER) behavior of suspensions in silicone oil of phosphoric ester cellulose particles (average particle size : 18$\pm$1${\mu}{\textrm}{m}$) coated with octadecylamine ( $C_{18}$ $H_{37}$ N $H_2$) as surfactant was investigated at room temperature. For development of anhydrous ER suspension using at real application, it should be researched how can reduce deposition of ER particles in ER suspension. Anhydrous ER suspensions mixing with phosphoric ester cellulose particles coated with octadecylamine were measured. As increasing the coating concentration of octadecylamine, not only analysis of electrical properties such as dielectric constant, current density and electrical conductivity but also rheological properties of ER suspensions were studied. From the experimental results, coating concentration of surfactant had large influence to ER properties of anhydrous ER suspension. Current density, conductivity and electrorheological effect ($\tau$/$\tau$$_{0}$) of ER suspension were linearly reduced with increasing the coating concentration of octadecylamine. But ER suspensions dispersed the phosphoric ester cellulose particles coated with octadecylamine showed reducing deposition of ER particles and could be redispersed easily.