• 한국산업보건학회지
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• 제7권1호
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• pp.49-59
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• 1997

This study was performed to analyze the purity of technical grade ${\alpha}$-naphthylamine, to establish optimal analytical condition of ${\alpha}$-naphthylamine in urine and to determine the urine sample of workers exposed to ${\alpha}$-naphthylamine. The purity of technical grade ${\alpha}$-naphthylamine were $96.5{\pm}2.38%$, $94.1{\pm}0.97%$, $97.0{\pm}0.02%$ by gas chromatography-mass selective detector. To analyze ${\alpha}$-naphthylamine in urine, high performance liquid chromatography-electrochemical detector and gas chromatography-electron capture detector operating conditions have been optimized by preliminary expriment. In high performance liquid chromatography-electrochemical detector, the mobile phase was consisted of acetonitrile(35%) and water(65%), and the flow rate was maintained at 1.0ml per minute. Optimal detective condition was 9.0V(10nA/V) of electrochemical detector. The recovery of sep-pak treatment method was highly estimated as pretreatment of ${\alpha}$-naphthylamine in urine. The free amine was isolated by gas chromatography-electron capture detector after basic hydrosis, sep-pak treatment, toluene elution and HFBA(heptafluoro-butyric anhydride) derivatization of urine. The recovery of ${\alpha}$-naphthylamine in urine was $98.73{\pm}3.29%$ by gas chromatography-electron capture detector. The sensitivity was more higher than that of high performance liquid chromatography-electrochemical detector. Urinary ${\alpha}$-naphthylamine was detected in only one worker among nine workers. The level of ${\alpha}$-naphthylamine in urine was 6.42 ng/ml.

• Toxicological Research
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• 제3권1호
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• pp.27-32
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• 1987

Ethyl acetate extracts of 6 commercial amaranths produced in 1985 and 1986 were analyzed with a gas chromatograph. The ${\alpha}$-naphthylamine ranging from 142 ppb to 4216 ppb was detected, but the ${\beta}$ naphthylamine was not detected. The mutagenicity of the ethyl acetate extract was tested using Salmonella typhimurium TA100 in the presence of the S-9 fraction. Significant mutagenic activity was seen in samples containing high levels of ${\alpha}$-naphthylamine. It is suggested that the potential hazard of amaranth to the general public should be reconsidered from the point that the impurities contained in amaranth preparations are the main sources of mutagenicity or carcinogenicity.

• 대한화학회지
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• 제5권1호
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• pp.60-65
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• 1961

Nowadays, it is a well-known fact that the epoxy resins play an important role in the industrial field of plastics because of their excellent properties. Although studies on the polymers of epichlorohydrin with phenols, up-to-date, were various, there were only a few wokrs on the polymers of epichlorohydrin with amines. Therefore the experiments are carried out about the polymerization of epichlorohydrin with ${\alpha}-, {\beta}$-naphtylamine, o-, m-, p-toluidine, and o-, m-, p-nitroaniline. Examining the polymerization processes and the differences in the properties of the polymers, we obtained the following conclusions. 1) ${\alpha}$-naphthylamine, ${\beta}$-naphthylamine, o-toluidine, m-toluidine and p-toluidine react with epichlorohydrin to form polymers but o-, m-, and p-nitroaniline do not make polymers with epichlorohydrin. 2) As polymerization times after adding sodium hydroxide and refluxing again 3hrs. are suitable for ${\alpha}$-naphthylamine-epichlorohydrin, 3.5hrs. for${\beta}$-naphthylamine-epichlorohydrin, and 4hrs, for m-toluidine-epichlorohydrin. 3) Method for determining molecular weight of these polymers by the titration of end group is applicable to the polymers having D.P. less than about 200 for ${\alpha}$-, ${\beta}$-naphthylamine-epichlorohydrin and those having D.P. less than 18 for m-toluidine-epichlorohydrin. 4) Gererally, these polymers get special colors so that these need proper pigmentation to use as molding compounds.

• 한국작물학회:학술대회논문집
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• 한국작물학회 1988년도 정기총회 및 학술연구발표회
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• pp.14-15
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• 1988

• 한국작물학회:학술대회논문집
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• 한국작물학회 1988년도 정기총회 및 학술연구발표회
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• pp.16-17
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• 1988

• 멤브레인
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• 제7권3호
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• pp.131-135
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• 1997

신규 고분자형 계면활성제($\alpha$-allyl-$\omega$-methoxy polyoxyethylene and maleic anhydride block copolymer)를 사용하는 고분자형 마이셀 촉진 한외여과법을 제안하였다. 제거용질로서는 염료의 중간체이며 발암성 물질인 1-나프틸 아민을 사용하였다. 고분자형 마이셀의 촉진효과는 중공사형 폴리아크리로니트릴 막(분획 분자량 6,000, 표면적 0.017$m^2$)을 사용하여 조사하였다. 플럭스의 선형의존성은 0.6kg/${cm}^2$까지 유지되었고, 점차 압력증가에 따라 플럭스 증가율은 감소하였다. 고분자형 마이셀을 첨가하지 않은 상태에서의 제거율은 2mM의 용질에 대하여 0.19, 2 wt.%의 고분자를 첨가한 상태에서의 제거율은 0.96이었다 고분자형 마이셀 내부로의 가용화가 분리효율을 5배 촉진시킨 것을 확인하였다.

• 한국산림과학회지
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• 제84권3호
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• pp.361-368
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• 1995

표고버섯 원목(原木) 재배(栽培)에 있어서 골목화 기간을 단축하여 해균(害菌)의 침입을 막고 생산량 증대를 위한 방법으로 생리활성화물질(生理活性化物質)이 표고버섯 골목화에 미치는 영향을 실험분석하였다. 생리활성화물질은 파(Allium fistulosm), 보리(Hordeum vulagare var. hexastichon), 표고버섯(Lentinus edodes), 당근(Daucus carota var. sativa), 유자(Citrus junos)를 사용하였는데 그 중 파(Allium fistulosm)의 추출액이 제일 유효하였으며, 생리활성화물질(生理活性化物質)에 효과가 높은 수종(樹種)은 굴참나무(Quercus variabilis)로 나타났다.

• 한국재료학회지
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• 제15권7호
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• pp.448-452
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• 2005

This study was based on organic electroluminescence display. Especially, TPD and $\alpha-NPD$ for the hole transport materials were synthesized by Ullmann reaction. This reaction was conducted between 3­methylphenylamine, 1-naphthylamine and 4,4'-diiodobiphenyl in toluene containing CuCl catalyst and KOH base. The structural property of reaction products were analyzed by FT-IR, $^1H-NMR$ spectroscopy, and thermal stability, reactivity and PL property were analyzed by melting point, yield and emission spectrum, respectively. The photoluminescence spectra of a pure TPD and $\alpha-NPD$ were observed at approximately 416nm and 438nm respectively. In this study, it was known that the melting point, yield, PL properties of TPD and $\alpha-NPD$ were changed by substituent group of amines.

• 한국수산과학회지
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• 제8권4호
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• pp.213-216
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• 1975

항산화제 및 약제처리가 옥돔 건제품의 품질에 미치는 영향을 실험한 결과 Tenox-II가 가장 산패방지 효과가 좋았고, 다음이 BHA, sustane, NDGA였으며, EDTA, 솔빈산 칼리움, CTC, $\alpha-naphylamine$은 효과가 없었다. 옥돔은 $0.1\%$ Tenox-II용액에 침지처리하여 건조한 다음 PVC 필름에 포장하여 저장하면 4개월간 품질을 안정하게 유지할 수 있었다.

• 약학회지
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• 제18권1호
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• pp.59-73
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• 1974

Fifteen derivatives of phthalide were synthesized from m-hemipinic, hydrastic and 4,5-benzophthalic anhydride with acetic, phenylacetic, p-methoxyphenylacetic, p-nitrophenylacetic, ${\alpha}$-nephthylacetic and succinic acid by the Gabriel condensation. In the same way, 13 derivatives of phthalimidine and 4 derivatives of ${\alpha,\beta}$ -benzisothiazoline-1, 1-dioxide were synthesized from diphenylmaleimide, phthalimide, saccharine and 4,5-benzo-phthalimide with previous 6 acids. 3-Substituted derivatives of m-hemipinic anhydride, hydrastic anhydride and 4,5-benzophthalic anhydride were treated with formamide and seven 3-substituted imidines could be synthesized. In case of 4,5-benzophtha lide, two isomers,4,5-benzophthalidene-3-acetic acid and 4,5-benzophthalidene-1-acetic acid, can be obtained theoretically, but only one product we got, and the chemical structure of it was identified by the following way. It was hydrolyzed and then decarboxylated, and this decomposed product was identical with 1-acetyl-2-naphthoic acid which was synthesized from .betha.-naphthylamine. This indicates that by the Gabriel condensatioin 4,5-benzophthalide only produces 4,5-benzophthlidene-3-acetic acid, that is ${\alpha}$-carbonyl substitute.