• 대한핵의학회:학술대회논문집
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• 1997.05a
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• pp.183-183
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• 1997

• 대한핵의학회:학술대회논문집
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• 2001.11a
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• pp.33.3-33.3
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• 2001

• The Korean Journal of Nuclear Medicine
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• v.31 no.4
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• pp.459-463
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• 1997

핵의학적 유방영상법은 오랜동안 시범되어 왔지만 임상에서 큰 역할을 못했고, 근래에 핵의약품과 핵의학기기 사용방법의 발전으로 scintimammogram(SM)이 다시 각광을 받게 되었다. 유방암 진단에 대한 핵의학영상법의 특이도와 예민도가 방사선 유방촬영법보다 높다고 보고되었으나 1cm보다 작은 유방암은 SM에 용이하게 발견되지 않는다. 본 보고에서는 1cm보다 작은 유방암이 발견된 두 증례를 발표한다. 한증례는 $^{99m}Tc$ MDP를 수술전 골영상을 위해서 사용하였고, 두 번째 증례는 비촉지 유방종괴를 $^{99m}Tc$ MIBI로 유방촬영 하였다.

• The Korean Journal of Nuclear Medicine Technology
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• v.13 no.3
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• pp.92-101
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• 2009

Purpose: Scintimammography is one of the screening tests for the early diagnosis of breast cancer. It has been widely accepted as very useful in assessing masses that have not been detected in breast scanning. This method is highly sensitive and specific with respect to the diagnosis of primary and relapsing breast cancer. It has some difficulties, however, in detecting tumors sized 1 cm and below due to the radioactivity around the breast and the geometrical structure of the equipment. The recent introduction of high-resolution Breast-specific Gamma Imaging (BSGI) has made it possible to more accurately discriminate between malignant and benign tumors than with any other test method. Thus, the possibility of an unnecessary biopsy being performed has decreased. The purpose of this study was to examine the diagnostic capacity of mammography, breast sonography, and scintimammography, which are used for the early diagnosis of known breast cancer, and of BSGI, and to evaluate the skillfulness of radiologists. Materials and Methods: The 53 volunteers participants who had no clinical manifestation of breast cancer underwent the BSGI in February 2009. In the BSGI procedure, scanning images were obtained from the craniocaudal projection (CC) and the mediolateral Oblique projection (MLO), as well as from the additional $80{\times}80$-matrix-sized views at various angles in the Present Time method, 10 minutes after the 25 mCi $^{99m}Tc$-MIBI was injected. Results: The results of the BSGI showed that two participants had masses in their breast tissue. As the results of the diagnosis of four participants were not clear, they were retested and the results of the second test were negative. The results of the clinical screening test for breast cancer showed that the sensitivity of BSGI, scintimammography, mammography, and breast sonography was 86.5%, 77.8%, 85~90%, and 66.7%, respectively, and that their specificity was 92.4%, 84.2%, 20~42%, and 68%, respectively. Conclusion: The autodiagnosis and breast cancer screening test are needed for the early diagnosis of breast cancer. It was not easy, however, to accurately determine the presence of a mass in the breast using the existing breast cancer screening test. The patients with unclear test findings were made to undergo a histologic biopsy for a more accurate diagnosis. It is expected that the BSGI can provide useful information for the early diagnosis of breast cancer and of primary breast cancer, and will reduce the performance of unnecessary biopsies because of its higher sensitivity and specificity than existing breast cancer screening tests.