• 대한핵의학회지
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• 제30권3호
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• pp.338-343
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• 1996

삼상골스캔을 이용한 골 섭취도의 평가는 비교적 간단한 방법으로 이것으로 평가한 만성 신부전환자 14명의 골 섭취도는 정상인 보다 유의하게 증가되어 있었다. 또한 골 모세포의 활동성의 지표로 알려진 osteocalcin과 골 대사 호르몬인 부갑상선 호르몬의 혈중농도도 정상대조군에 비하여 만성 신부전 환자에서 월등하게 높았다. 하지만 이렇게 산출한 골 섭취도와 osteocalcin, 부갑상선 호르몬 사이에는 직접적인 연관성은 미약하였다. 따라서 삼상골스캔을 이용한 골 섭취도의 정량화가 보다 객관적인 평가 방법이라고 인정받기 위하여서는 좀 더 많은 연구가 필요하다고 본다.

• 대한방사선기술학회지:방사선기술과학
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• 제17권1호
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• pp.77-86
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• 1994

The bone scan reflects the metabolic reaction of bone to a disease process, whether neoplastic, traumatic or inflammatory. In normal bone tissue, the labeled diphosphate complexes accumulate in the perivascular fluid next to the marrow cavity at the interface between uncalcified and calcified bone matrix. HMDP has the most rapid plasma clearance among the commonly used diphosphonate followed by MDP and then HEDP. I have studied about bone scan time by use of $^{99m}Tc-MDP$, and got 336 images from 112 patients. The result obtained as follow; 1. Accumulation rate of $^{99m}Tc-MDP$ is higher than other age groups in below 30-year old group. 2. Accumulation rate, in 10year old group, is 75.85% on 120min. but other groups are most high on 180 min. 3. The density differants between bone and soft tissue increased with time. 4. Image contrast is good in younger group than old.

• Imaging Science in Dentistry
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• 제49권1호
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• pp.53-58
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• 2019

Purpose: To present characteristic findings of Tc-99m hydroxymethylene diphosphonate (HMDP) scintigraphy, computed tomography (CT), and magnetic resonance (MR) imaging for osteonecrosis in the mandible, especially osteoradionecrosis(ORN) and medication-related osteonecrosis of the jaw(MRONJ). Materials and Methods: Thirteen patients with MRONJ and 7 patients with ORN in the mandible underwent Tc-99m HMDP scintigraphy, CT, and MR imaging (T1-weighted images[T1WI], T2-weighted images[T2WI], short inversion time inversion recovery images[STIR]), diffusion-weighted images[DWI], and apparent diffusion coefficient [ADC] mapping). The associations of scintigraphy, CT, and MR imaging findings with MRONJ and ORN were analyzed using the chi-square test with the Pearson exact test. Results: Thirteen patients with MRONJ and 7 patients with ORN in the mandible showed low signal intensity on T1WI and ADC mapping, high signal intensity on STIR and DWI, and increased uptake on scintigraphy. Periosteal bone proliferation on CT was observed in 69.2% of patients with MRONJ(9 of 13) versus 14.3% of patients with ORN(1 of 7)(P=0.019). Conclusion: This study presented characteristic imaging findings of MRONJ and ORN on scintigraphy, CT, and MR imaging. Our results suggest that CT can be effective for detecting MRONJ and ORN.