• 제목/요약/키워드: $(P.S)^*$ condition

검색결과 2,788건 처리시간 0.032초

Effects of opioid and non-opioid antagonists, pH and enzymes on Corchorus olitorius antinociception in mice

  • Zakaria Zainul Amiruddin;Neelendran M;Pubalan S;Sulaiman MR;Fatimah CA
    • Advances in Traditional Medicine
    • /
    • 제6권3호
    • /
    • pp.186-195
    • /
    • 2006
  • The present study was carried out to determine the involvement of opioid and non-opioid receptor and the effect of pH and enzymes on the recently reported antinociceptive activity of aqueous extract of Corchorus olitorius (AECO) leaves using the abdominal constriction test. The extract was prepared by soaking the dried powdered leaves of Corchorus (C.) olitorius in distilled water overnight, and the supernatant obtained was considered as a stock solution with 100% concentration/ strength. The extract, administered subcutaneously in the concentrations/ strength of 10, 50 and 100%, was found to show a significant concentration-independent antinociception. The 50% concentration AECO were further used to study on the above mentioned parameters. The extract exhibited: significant (P < 0.05) decreased in activity when pre-treated (s.c.) against 10 mg/kg naloxonazine, bicuculine (10 mg/kg), phenoxybenzamine (10 mg/kg), 10 mg/kg pindolol, and 5 mg/kg mecamylamme, but not 10 mg/kg naltrindole, 10 mg/kg atropine, respectively; significant (P < 0.05) decreased in activity after pre-treatment against 10% a-amylase, but not 1 % protease or 10% lipase and; significant (P < 0.05) decreased in activity after exposure to alkaline condition (pH between 9 and 13) while maintaining the activity at acidic condition, respectively. The C. olitorius leaves antinociception, which involved, at least in part, activation of $\mu-opioid,\;\alpha-and\;\beta-adrenergic$, and nicotinic receptors, was found to decrease under alkaline condition and in the presence of $\alpha-amylase$.

렌즈 무반사막 구조에 의한 반사색광의 특성 연구 (The Reflection Color Light with the Structure of an Antireflection Lenses)

  • 김용근
    • 한국안광학회지
    • /
    • 제1권1호
    • /
    • pp.93-102
    • /
    • 1996
  • 렌즈의 광학계의 분광투과률을 높이기 위한 방법으로 무반사막의 다층화에 의한 광대역화와 낮은 반사률이 중요하다. 그러나 잔류반사광이 발생하여 반사색광이 미약하게 나타난다. 이런 반사색광은 두께, 굴절율, 층수, 입사광의 파장, 기판물질 등의 구조에 의한 반사광의 파장 영역을 제어할 수 있다. l층, 2층 구조에서 ${\lambda}s/{\lambda}$=1.0인 조건하에서 무반사시키면, 다른 영역에서 나온 반사광들이 색혼합된 반사색광을 얻을 수 있고, 3층 구조에서 ${\lambda}0/{\lambda}$$PI{\ll}1$, $P2{\gg}1$ 에서 무반사시키면 P1< ${\lambda}0/{\lambda}$

  • PDF

119 구급대원의 직무만족도와 이직의도와의 관계 (The Relationship Between The Job Satisfaction and The Turnover Intention of 119 Emergency Medical Technicians)

  • 배기숙
    • 한국응급구조학회지
    • /
    • 제14권1호
    • /
    • pp.65-80
    • /
    • 2010
  • Objective : The objective of this study was to survey the job satisfaction and turnover intention of 119 emergency medical technicians who are fire fighters and, at the same time, provide emergency patients with first aid, to examine the correlation between their job satisfaction and turnover intention, and to provide basic materials for the human resource management of 119 emergency medical technicians. Method : The survey was conducted with 152 119 emergency medical technicians working at fire stations in an area of Gyeonggi-do during the period from July 15 to September 14, 2009. Job satisfaction was measured with a tool developed by Kim Sun-sim and Kwon Hye-ran (2002) based on the Index of Work Satisfaction, and turnover intention with the tool developed by Becker (2002) and translated and used by Cho Yeong-sook (2002). The questionnaire was composed of 11 questions on general characteristics, 35 on job satisfaction, and 4 on turnover intention, so a total of 50 questions. The reliability of the questionnaire was Cronbach's ${\alpha}=0.922$ for job satisfaction and Cronbach's ${\alpha}=0.854$ for turnover intention. Using SPSS 14.0, we obtained frequencies, percentages, means, and standard deviations, and performed independent two-sample t-test, one-way ANOVA, and Pearson correlation analysis, and Cronbach's ${\alpha}$. Results : 1) The mean score of the 119 emergency medical technicians' job satisfaction was 2.71, and that of their turnover intention was 2.64. By area of job satisfaction, the mean score was 3.44 for the area of job itself, 2.92 for the interaction area, 2.67 for the organizational demand area, 2.64 for the autonomy area, 2.14 for the wage area, and 1.91 for the working condition area, showing that emergency medical technicians were generally satisfied with their job itself but not with their working condition. 2) As to difference according to the 119 emergency medical technicians' general characteristics, statistically significant difference was observed in job satisfaction according to license type (F = 4.729, p < .010), and in turnover intention according to position (F = 3.768, p < .025). 3) The 119 emergency medical technicians' job satisfaction and turnover intention was in a negative correlation with each other (r = -.44, p < .000) in general, and by the sub-areas of job satisfaction, the correlation with turnover intention was high in order of the autonomy area (r = -.42, p = .000), interaction area (r = -.42, p = .000), job itself (r = -.35, p < .000), organizational demand area (r = -.30, p = .000), wage area (r = -.23, p = .000), and working condition area (r = -.21, p = .008). Conclusion : The 119 emergency medical technicians' job satisfaction showed a negative correlation with their turnover intention. This suggests that turnover intention can be reduced by improving job satisfaction. Furthermore, 119 emergency medical technicians' job satisfaction was high with the job itself, showing their high pride in their job, but was low with working condition and wage. Thus, it is necessary to enhance their job satisfaction by improving the 24-hour work system through supplementing manpower, compensating for overtime works, adjusting work hours per week, etc. These results are expected to be useful in making human resource management plans to lower turnover intention by enhancing 119 emergency medical technicians' job satisfaction.

  • PDF

서울지역 일부 보건소 공무원의 지각된 건강상태와 건강행동과의 관련성 -Pender의 건강증진모델을 이용하여- (A Study on Factors Affecting Public Health Center Workforce for Health Behavior based on Pender's Health Promotion Model)

  • 이은정;이명선
    • 한국학교ㆍ지역보건교육학회지
    • /
    • 제15권1호
    • /
    • pp.121-140
    • /
    • 2014
  • Objectives: Recently, the rate of death by chronic disease, is increasing steadily. To prevent this, the public health center will have taken a leading role in the local community medical business through an establish to the national health promotion act and an amendment to the law of public health center in Korea. Results: Accordingly this research, using the Pender's health promotion model which is related with subject health behavior who government employees serve at the public health center have taken important position in the local community health promotion, have comprehended the actual condition of health behavior. For increasing the health behavior practice of subject to comprehend the factor which have effect on health behavior practice, which can be a correct role model in the local community health promotion. A survey was performed on 406 government employees who serve at five public health centers in Seoul. The period of survey was from 25th October, 2010 to 15th November, 2010. The results of this study were summarized as below. 1. Work-related stress, perceptible beneficial obstacle, and self-efficacy were composed by 5 points measure. The results show those work-related stress were $3.06{\pm}0.469$, 74perceptible beneficial obstacle were $3.74{\pm}0.471$, and self-efficacy were $3.49{\pm}0.469$. 2. As for the health behavior by general characteristic, the results have specific differences on age, education level, state of marriage, rank of the position, field of the occupation and employment forms in statics analysis. 3. As for the past health behavior by health behavior characteristic, work-related stress have specific differences on the past frequency of drinking (p<.05) in statics analysis, perceptible beneficial obstacle have specific differences on the past frequency of having breakfast(p<.05), having snacks(p<.05) and doing exercise(p<.05) in statics analysis. Self-efficacy have specific difference on the past frequency drinking(p<.01) in statics analysis. 4. According to the correlation between the factors related with health behavior and health behavior, the health behavior have specific differences on perceptible health condition(p<.01), the past health behavior and perceptible beneficial obstacle(p<.05). Work-related stress and self-efficacy don't have specific relation in health behavior practice. 5. The factors, which effect on health behavior practice have specific differences on the past health behavior, employment forms and field of the occupations. The ability of explanation occupied 54.8% what explained of the health behavior practice by general characteristic, perceptible health condition, employment forms and perceptible beneficial obstacle. Conclusions: According to the correlation between the factors related with health behavior, the health behavior have specific differences on perceptible health condition(p<.01), the past health behavior and perceptible beneficial obstacle(p<.05). The factors, which effect on health behavior practice have specific differences on the past health behavior, employment forms and field of the occupations.

  • PDF

Collins 내동기의 최적 설계조건 (Optimum Design Condition of the Collins Cryocooler)

  • 이상원;김수연;정평석
    • 설비공학논문집
    • /
    • 제4권3호
    • /
    • pp.183-190
    • /
    • 1992
  • The Collins cryocooler is numerically analysed with the optimization technique, and the optimum operating and design conditions are searched. This paper shows that liquefied helium quantity has an external maximum w.r.t. the total mass flow rate, the mass flow rates through expander and the capacities of heat exchangers. The liquefied helium quantity increases as the compressor exit pressure of the cryocooler does. The maximum quantity of liquefied helium and the maximum coefficient of performance have been found to exist in extremum, depending on the ratios of each heat exchanger capicities to the total one. At the optimum condition, the capacity of heat exchanger in high temperature region is larger than that in low temperature region.

  • PDF

부재료 첨가량을 달리한 오이 김치의 저장 기간에 따른 품질 변화 (Quality Changes of Cucumber Kimchi Prepared with Different Minor Ingredients during Fermentation)

  • 백재은;정현아;배현주
    • 한국식품영양학회지
    • /
    • 제19권4호
    • /
    • pp.473-481
    • /
    • 2006
  • This study was carried out to investigate the properties of cucumber kimchi prepared with different minor ingredients(potato, puchu). Acidity, pH, color value, hardness, and lactic acid bacteria were measured under the condition of $10^{\circ}C$ for 25 days. Five conditions of making cucumber kimchi included: cucumber kimchi with puchu 300g(treatment 1, control), cucumber kimchi with potato 90g, puchu 210 g(treatment 2, 5-1), cucumber kimchi with potato 150g, puchu 150 g(treatment 3, S-2), cucumber kimchi with potato 210g, puchu 90 g(treatment 4, S-3), cucumber kimchi with potato 270g, puchu 30g(treatment 5, S-4). Hardness of cucumber kimchi appeared higher values as the potatoe's volume increased(S-1, S-2, S-3, S-4), during all fermentation days. The results showed very significant values in pH(p<0.001), acidity(p<0.001), 'L' of lightness(p<0.05), hardness(p<0.001), lactic acid bacteria(p<0.001) according to fermentation. And the results showed very significant values in 'a' of redness(p<0.01), hardness(p<0.001) according to cucumber kimchi samples. These results showed that fermentation patterns of cucumber kimchi were influenced by the different minor ingredients used.

한센노인의 체간운동이 슬관절 굽힘·폄 동작의 최대수축 시 근피로도에 미치는 영향 (Effects of Muscle Fatigue through Maximum Contraction during Flexion and Extension of Knee Before and After Isometric Trunk Exercise on Elderly Hansen's Disease)

  • 정순미
    • 한국운동역학회지
    • /
    • 제21권1호
    • /
    • pp.115-121
    • /
    • 2011
  • This study was to investigate the change of muscle fatigue through maximum contraction during flexion and extension of knee joint before and after the isometric trunk exercise was implemented on elderly Hansen's disease. 18 subjects exercised for 60 minutes twice a week for 12 weeks. The subjects were divided into normal sensory group, group with sensory loss in left sole, group with sensory loss in right sole, and group with sensory loss in both soles, according to the sensory condition on their soles. We obtained following results. Muscle fatigue in normal sensory group, there were significant differences in left right hamstring, left rectus femoris(p<.05), in group with sensory loss in left sole, there were significant differences in left right hamstring(p<.05), in group with sensory loss in right sole, there were significant differences in left right hamstring, right rectus femoris and group with sensory loss in both sole, there were significant differences in right hamstring(p<.05). The differences of muscle fatigue according to the sensory condition on their soles, there were significant differences in left hamstring between normal sensory group and group with sensory loss in both sole(p<.05).

쌀가루를 첨가한 양배추 크림수프의 제조조건 최적화 (Optimization of Mixing Condition of Cabbage Cream Soup)

  • 박소연;표서진;주나미
    • 한국식생활문화학회지
    • /
    • 제25권1호
    • /
    • pp.54-60
    • /
    • 2010
  • The principal objective of this study was to determine the optimal mixing condition of two different amounts of cabbage and rice flour for the preparation of a cabbage cream soup. The experimental design was based on the central composite design methodology of response surface, which included 10 experimental points, including two replicates for the cabbage and rice flour. Physiochemical and sensory properties were measured, and these values were applied to the mathematical models. A canonical form and perturbation plot showed the influence of each ingredient on the mixed final product. Water content and pH values increased with increasing quantities of rice flour. Neither cabbage or rice flour affected the L and a values, but the b value increased with greater quantity of both ingredients. Viscosity increased with increasing added cabbage. Sensory evaluation results were significant in the predicted model for flavor (p<0.05), concentration (p<0.01) and overall quality (p<0.01). As a result, the optimum formulations by numerical and graphical methods were calculated as 111.79 g cabbage and 8.99 g rice flour.

Electroporation에 의한 근권 미생물 Pseudomonas fluorescens의 형질전환 (Transformation of Rhizobacteria Pseudomonas fluorescens by Electroporation)

  • 김종현;이영환
    • Applied Biological Chemistry
    • /
    • 제38권5호
    • /
    • pp.371-375
    • /
    • 1995
  • 식물 병원성 사상균 F. oxysporum과 R. solani에 대하여 우수한 길항력을 갖는 Pseudomonas (P.) fluorescens를 작물 근권으로 부터 분리하여 생리, 생화학적 특성을 조사하였다. 이들 분리 근권길항 미생물중 한 균주인 Ps70과 plasmid pSV2-neo를 이용하여 electroporation에 의한 길항 미생물 P. fluorescens의 transformation 가능성과 최적 조건을 조사하였다. 그 결과 10% glycerol을 P. fluorescens buffer로 사용하여 2.5kV의 voltage, $200{\Omega}$의 resistance에서 최적의 electrotransformation 효과를 보였다. 또한, 이균주에 크기가 서로 다른 plasmid를 electroporation하여 transformation 효과를 비교한 결과 voltage, electroporation buffer의 조성, 그리고 resistance (time constant)가 transformation의 효과를 증진하는데 주요한 역할을 하는것으로 나타났으며, 또 다른 P. fluorescens 균주에 같은 실험을 반복한 결과 유사한 electrotransformation 효과를 보였다.

  • PDF