• Korean Journal of Environment and Ecology
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• v.15 no.2
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• pp.104-117
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• 2001

경상북도 낙동상 상류부에 위치한 하천변 식물군락에 대해 식물사회적 조사를 하였다. 그 결과 아래처럼 10군강에 속하는 30군락단위와 상급단위 미결정의 1군락단위를 식별하였다. 특히, 과거에 인위적 영향을 반영하여 쑥군강에 속하는 군집 군락이 가장 많이 출현하였다. A. 관목식물군락-A-1나도버들군장, 버드나무군단: 버드나무-왕버들군집, 버드나무군집, 시무나무군집, 갯버들군집, 눈갯버들군집, 선버들군집, A-2 찔레꽃 군강: 국수나무군락, 구기자나무군락: A-3 상급단위 미결정의 군락: 누리장나무군락; B, 초본식물군락 B-1 가래군강: 노랑어리연꽃군집, 마름군락, B-2 좀개구리밥군강: 좀 개구리밥-개구리밥군랍, B-3 가막사리군강: 고마리군집, 미꾸라지낚시-여뀌군집, 개기장-여뀌군집, B-4 갈대군강; 창포군집, 갈풀-미나리군집, 달뿌리풀군집, 물억새군집, 갈대군락, B-5 쑥군강:물쑥군집, 쑥군락, 물봉선군락, 왕고들빼기-환삼덩굴군집, 칡-환삼덩굴군집, 수크려군랑, B-6 명아주군강: 물피군락, 바랭이군란, 큰개여뀌군락, B-7 억새군강: 억새군락, B-8 질경이군강: 비노리-질경이군락, 이들 식생단위는 거의가 일본의 것과 공통하고 있어 한국에 고유한 하천변 식생은 매우 드물다는 사실을 나타내었다. 한편 하천에는 고유한 군강의 군집, 군락은 하류에서 상류로 감에 따라 양적으로 증가 하였으마, 귀화식물의 수는 그 반대였다. 또, 각 군락과 환경과의 관계, 하천변 식생의 복원생태 및 자연보호 등에 관해 상세히 논하였다.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.19 no.3 s.31
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• pp.34-54
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• 2006

The effects of four extracts of medicinal herbs, Rubus coreanum, Acorus calamus, Morus alba and Rehmannia glutinosa on hair growth activity and acnes control were investigated. In the course of screening natural extracts for hair growth, we found that the extract of dried root of Rubus coreanum has the hair growth promoting effect. After topical application of these extracts to the back of C57BL/6 mice, the earlier conversion of telogen-to-anagen phase was induced. The growth of dermal papilla cells and mouse vibrissae hair follicle cultured in vitro, however, was not affected by treatment of these extracts. Furthermore these extracts do not possesspotent inhibitory effect on $5{\alpha}-reductase$ I and II activity and anti-bacterial effect on Escherichia coli , Propionibacterium acnes, Pityrosporum ovale, Staphylococcus aureus, Staphylococcus epidemidis, and Candida albicans. RT-PCR analysis showed that these extracts did notinduce mRNA levels of growth factors such as insulin-like growth factor-I, keratinocyte growth factor, hepatocyte growth factor and vascular endothelial growth factor in dermal papilla cells. These results suggest that Rubus coreanum has hair growth promoting effect. However, the effects of these materials on the hair growth promotion are not mediated through inhibition of $5{\alpha}-reductase$ I and II activity, stimulation of hair follicle cells and expression of growth factors in the dermal papilla cells.

• The Journal of Internal Korean Medicine
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• v.29 no.3
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• pp.608-620
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• 2008

Objectives : This study investigated the protective effects of the water extracts of Chongmyung-tang, Polygalae Radix, and Acori Graminei Rhizoma in an in vivo Alzheimer's disease (AD) mouse model. Methods : Memory impairment was induced by an intraventricular injection of $A{\beta}25-35$ peptides and subsequently Chongmyung-tang, Polygalae Radix, or Acori Graminei Rhizoma extract were administered orally for 14days. Results : In the water maze task, Chongmyung-tang, Polygalae Radix, and Acori Graminei Rhizoma extracts improved learning ability during the acquisition period and significantly increased memory scores during the retention period versus $A{\beta}-injected$ controls. Furthermore, the toxicity of $A{\beta}25-35$ on hippocampus was assessed immunohistochemically (Tau, MAP2, TUNEL, Bax) and by in vitro study. Chongmyung-tang, Polygalae Radix, and Acori Graminei Rhizoma demonstrated significant neuroprotective effects against oxidative damage and apoptotic cell death of hippocampal neurons damaged by $A{\beta}25-35$. Conclusions : These results suggested that Chongmyung-tang, Polygalae Radix and Acori Graminei Rhizoma extract improve memory impairment and reduce Alzheimer's dementia via anti-apoptotic effects and by modulating the expressions of Tau and MAP2 protein in the hippocampus.

• Journal of Oriental Neuropsychiatry
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• v.13 no.2
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• pp.173-194
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• 2002

Alzheimer's disease(AD) is a geriatric dementia that is widespread in old age. In the future AD will be the largest problem in public health service. From old times, Much medicines have been used for treatment of dementia, but there is no medicine having obvious effect. AD is one of brain retrogression disease. So We studied on herbal medicine that have a relation of brain retrogression. From old times, In Oriental Medicine, Rhizoma Acori Graminei has been used for disease in relation to brain retrogression. We studied on the effects of anti-Alzheimer in pCT105-induced neuroblastoma cell lines by Rhizoma Acori Graminei extract As the result of this study, In RAG group, the apoptosis in the nervous system is inhibited, the repair against the degerneration of Neuroblastoma cells by CT105 expression is promoted. These results indicate that RAG possess strong inhibitory effect of apoptosis in the nervous system and repair effect against the degeneration of Neuroblastoma cells by CT105 expression.

• Journal of the Korean Institute of Landscape Architecture
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• v.32 no.5
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• pp.63-72
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• 2004

This study was carried out to analyze effects of soil, water level and shading on growth of sweet flag(Acorus calamus var. angustatus). Three types of soil were used, which included sandy, silty loam and paddy loam soil. Three levels of shading were applied in the experiment: no shading, 55％ shading and 75％ shading. The water levels were also adjusted to three levels in the experiment. The results are summarized as follows; 1. The cultivation of sweet flag in sandy soil with low water level resulted in decreased fresh weight compared to that at planting. This result indicates that the water level should be maintained higher than the soil surface for sweet flag growth in sandy soil. 2. 5 out of 72 sweet flags died in paddy loam soil. Water saturation of soil easily reduced paddy loam soil, and root growth of sweet flags in reduced soil condition were restricted, resulting in the dead plants. 3. The growth of sweet flag in paddy loam soil was worse than those in silty loam, indicating that reduced soil conditions in paddy loam is harmful to root growth. In planting sweet flags in paddy loam, improved soil aeration in paddy loam soil is necessary for good growth of sweet flag. 4. The maintaining of high water levels is better than that of low water levels in sweet flag cultivation. During winter, soil near the water surface froze and sweet flags in frozen soil were stressed physiologically. Maintaining high water levels prevents soil from being frozen which is good for the growth of sweet flags. 5. There was not significant difference in the growth of the sweet flag between non-shading and 55％ shading. It thus appears that sweet flags can grow soundly under shading rate lower than 55％.

• The Korea Journal of Herbology
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• v.23 no.4
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• pp.149-157
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• 2008

Objectives: This study was to analyze the content changes of ${\beta}$-asarone and ${\alpha}$-asarone in A. gramineus according to its parts, extraction method, and fermentation. Methods: The change of ${\beta}$-asarone and ${\alpha}$-asarone was analysed with GC/MS, IR, and NMR. Results: In A. gramineus, ${\beta}$-asarone and ${\alpha}$-asarone in rhizome are 7 times and 4 times more than those in leaves respectively. And, in water extract of Acori Graminei Rhizoma, ${\beta}$-asarone was reduced to 77.8%-83.5%, and ${\alpha}$-asarone was reduced to 69.4%-72.2% compared with 50% MeOH extract. The amounts of ${\beta}$-asarone and ${\alpha}$-asarone were decreased apparently by 1 and 3 weeks fermantation with yeast activated solution. Conclusions: There was a change in the content of asarone pursuant to the medicinal part, extraction solvent, and fermentation. This result can be used as the basic data contributing to the stability of A. gramineus according to an appropriate clinical application.

• The Korea Journal of Herbology
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• v.26 no.1
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• pp.13-19
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• 2011

Objective : This study was to compare antioxidant activity and HPLC pattern analysis from 4 species of changpo(ch$\={a}$ngp$\'{u}$). Methods : To compare the antioxidant activity and HPLC pattern analysis from the 4 species of changpo, we performed the in vitro anti-oxidative activity assays and HPLC analysis from 70% ethanol extracts of Acorus gramineus Sol. (=AG), A. tatarinowii Schott (=AT), A. calamus L. (=AC) and Anemone altaica Fisch. ex C.A.Mey (=AA) taken in the herbal medicine market of Korea. Results : AG has the most effective anti-oxidative activity among 4 species of changpo. As the HPLC pattern analysis, AT was detected the unknown peak at retention time 14.9 min whereas AG was not showed any peak at the same retention time. These results suggest that AG could be used rather than AT when it need to be prescribed as anti-oxidative medicine. Conclusions : This result can be used as the basic data contributing to the stability of AG according to an appropriate clinical application.

• Journal of Life Science
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• v.19 no.6
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• pp.756-764
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• 2009

Scutellariae baicalensis GEORGt Acorus gramineus SOLAND and Gastrodia elata BLUME are traditional medicines used in the treatment of incipient stoke. In this study we investigated their effects on various aspects of neuronal differentiation in single or composite forms. Water-extracts of these medicines showed neuroprotective effects on cultured rat cortical neurons in normoxia and hypoxia. To understand the mechanism for neuroprotection we carried out various cell biological assays. They stimulated initial differentiation of neuronal development (transition from stage 1 to 2), and increased the number of spines and the length and number of dendritic processes. These effects were best manifested in the experimental group, which were given a mixture of the three kinds of extracts (p<0.01). To assess improvement of brain functions we carried out Morris water-maze tests for the mice that were fed on these extracts instead of water for 4 weeks. The experimental groups, especially those which were given the mixture of the three kinds of extract, showed significant (p<0.01) enhancement in memory as early as one day after the learning trial. These results indicate that these three kinds of extracts have synergistic effects on neuronal protection and improvement of brain functions.

• Korean Journal of Ecology and Environment
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• v.33 no.3 s.91
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• pp.304-310
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• 2000

Enclosure experiments to reduce the growth of Cyanophyceae were carried out using plants in Kyongan stream. Wet plants put into the enclosure at a rate of 2.5 g wet wt/l and at that time, the average concentration of chlorophyll a was ranged from 30 to $50\;{\mu}g/l$. The dominant species was Microcystis aeruginosa. Ginkgo, big cone pine and pine needles significantly inhibited the growth of Microcystis from the early days to the stages of log-Phase. Waterchestnut was the most inhibitory to the growth of Microcystis. Pine needles inhibited in 85% of the algal growth: ginkgo in 80%; big cone pine in 75%; waterchestnut in 78%; wildrice in 59%; and iris in 30%. At the treatment with 0.25 g dried plants/l, algae was declined at a rate of 90% by waterchestnut: 53% by pine needles. Phenolic compounds were purifled from decomposing big cone pine and waterchestnut.

• Journal of Haehwa Medicine
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• v.15 no.2
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• pp.231-238
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• 2006

In oriental medicine, Polygalae Radix & Acori Graminei Rhizoma are frequently used materials for the cardiac disorder(palpitaion), brain disorder(sleep disorder, forgetfulness, confused mind, dizziness). Bang-Yak-Hap-Pyun(方藥合編) is widely used for clinical herbal prescription book. In Bang-Yak-Hap-Pyun(方藥合編), Polygalae Radix is usually used 1don(錢)(4g) and Acori Graminei Rhizoma is used 1don(錢)(4g). The most important fact is that, in contrast to most people know that Polygalae Radix & Acori Graminei Rhizoma are used most prescription at the same time, the prescription used Polygalae Radix & Acori Graminei Rhizoma at the same time is merely 3. (Bang-Yak-Hap-Pyun percentage of Polygalae Radix & Acori Graminei Rhizoma is 0.64%). The number of prescription Polygalae Radix & Acori Graminei Rhizoma in Bang-Yak-Hap-Pyun is total 16. 10 in sang-tong(上統), 4 in jung-tong(中統), 2 in ha-tong(下統). The ratio of Polygalae Radix in Bang-Yak-Hap-Pyun is 0.41%~14.28%. And the ratio of Acori Graminei Rhizoma is 4%~16.66%. The mostly quoted medical literature what prescription included Polygalae Radix & Acori Graminei Rhizoma in Bang-Yak-Hap-Pyun is Tae-Pypng-Ha-Jae-Guk-Bang.