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http://dx.doi.org/10.4191/kcers.2011.48.6.577

Electron Spin Resonance (ESR) and Microwave Absorption Studies of Superparamagnetic Iron Oxide Nanoparticles (SPIONs) for Hyperthermia Applications  

Choi, Yong-Ho (Department of Materials Science and Engineering, Jungwon University)
Yi, Terry (Department of Sports Medicine, Jungwon University)
Kim, Do-Kyung (Department of Biomedical Science, Jungwon University)
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Abstract
Stabilized biocompatible superparamagnetic iron oxide nanoparticles (SPIONs) were prepared by controlled coprecipitation method for hyperthermia application. ESR measurements determined that all of the interactions in the individual SPIONs (1 nm and 11 nm) were antiferromagnetic in nature because the ions contributed to the magnetization with a range of magnetic moments. In-situ monitoring of the temperature increment was performed, showing that the microwave absorption rate of the SPIONs was dispersed in an appropriate host media (polar or non-polar solvents) during microwave irradiation. Microwave absorption energy rates and heat loss of SPIONs in solvent were calculated by non-linear data fitting with an energy balance equation. The microwave absorption rates of SPIONs dispersed in solvent linearly increases when the concentration of SPIONs increases, implying that the microwave absorption rate can be tunable by changing the concentration of SPIONs.
Keywords
Magnetite; Superparamagnetic; Iron oxide; Nanoparticles; Microwave absorption; ESR; SPIONs;
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1 J. Lasri, P. D. Ramesh, and L. Schachter, "Energy Conversion During Microwave Sintering of a Multiphase Ceramic Surrounded by a Susceptor," J. Am. Ceram. Soc., 83 [6] 1465-68 (2000).   DOI
2 A. Holzwarth, J. F. Lou, T. A. Hatton, and P. E. Laibinis, "Enhanced Microwave Heating of Nonpolar Solvents by Dispersed Magnetic Nanoparticles," Ind. Eng. Chem. Res., 37 [7] 2701-706 (1998).   DOI
3 C. Surig and K. A. Hempel, "Interaction Effects in Particulate Recording Media Studied by Ferromagnetic Resonance," J. Appl. Phys., 80 [6] 3426-29 (1996).   DOI
4 W. W. Tseng and S. P. L. Leong, "Long-term Survivors After Immunotherapy for Metastatic Melanoma," Immunol. Lett., 139 [1-2] 117-18 (2011).   DOI
5 D. P. Santos, M. A. Ruiz, V. Gallardo, M. V. B. Zanoni, and J. L. Arias, "Multifunctional Antitumor Magnetite/chitosan-lglutamic Acid (core/shell) Nanocomposites," J. Nanopart. Res., 13 [9] 4311-23 (2011).   DOI
6 C. S. S. R. Kumar and F. Mohammad, "Magnetic nanomaterials for Hyperthermia-based Therapy and Controlled Drug Delivery," Adv. Drug Deliv. Rev., 63 [9] 789-808 (2011).   DOI   ScienceOn
7 S. Laurent, S. Dutz, U. O. Hafeli, and M. Mahmoudi, "Magnetic Fluid Hyperthermia: Focus on Superparamagnetic Iron Oxide Nanoparticles," Adv. Colloid. Interface Sci., 166 [1-2] 8-23 (2011).   DOI
8 I. Pyykko, J. Zou, W. K. Zhang, and Y. Zhang, "Nanoparticlebased Delivery for the Treatment of Inner Ear Disorders," Curr. Opin. Otolaryngol. Head Neck Surg., 19 [5] 388-96 (2011).   DOI
9 S. M. Zhou, Y. Q. Guo, J. Y. Zhao, L. F. He, C. L. Wang, and L. Shi, "Particle Size Effects on Charge and Spin Correlations in $Nd_{0.5}Ca_{0.5}MnO_{3}$ Nanoparticles," J. Phys. Chem. C, 115 [23] 11500-506 (2011).   DOI   ScienceOn
10 L. Libioulle, A. Bietsch, H. Schmid, B. Michel, and E. Delamarche, "Contact-inking Stamps for Microcontact Printing of Alkanethiols on Gold," Langmuir, 15 [2] 300-4 (1999).   DOI
11 C. G. Granqvist and R. A. Buhrman, "Ultrafine Metal Particles," J. Appl. Phys., 47 [5] 2200-219 (1976).   DOI
12 D. K. Kim, Y. Zhang, W. Voit, K. V. Rao, and M. Muhammed, "Synthesis and Characterization of Surfactant-coated Superparamagnetic Monodispersed Iron Oxide Nanoparticles," J. Magn. Magn. Mater., 225 [1-2] 30-36 (2001).   DOI   ScienceOn
13 S. B. Oseroff, S. W. Cheong, B. Aktas, M. F. Hundley, Z. Fisk, and L. W. Rupp, "Spin-Peierls State Versus Neel State in Doped $CuGeO_{3}$," Phys. Rev. Lett., 74 [8] 1450-53 (1995).   DOI
14 Y. M. Wang, X. Cao, G. H. Liu, R. Y. Hong, Y. M. Chen, X. F. Chen, H. Z. Li, B. Xu, and D. G. Wei, "Synthesis of $Fe_{3}O_{4}$ Magnetic Fluid used for Magnetic Resonance Imaging and Hyperthermia," J. Magn. Magn. Mater., 323 [23] 2953-59 (2011).   DOI
15 E. P. Hui, V. W. Y. Lui, C. S. C. Wong, B. B. Y. Ma, C. P. Y. Lau, C. S. F. Cheung, K. Ho, S. H. Cheng, M. H. L. Ng, and A. T. C. Chan, "Preclinical Evaluation of Sunitinib as Single Agent or in Combination with Chemotherapy in Nasopharyngeal Carcinoma," Invest. New Drugs, 29 [6] 1123-31 (2011).   DOI
16 D. Z. Chen, K. Engel, and C. Wang, "A New Algorithm for a Field Splitting Problem in Intensity-Modulated Radiation Therapy," Algorithmica, 61 [3] 656-73 (2011).   DOI
17 S. Yagyu, T. Iehara, T. Gotoh, M. Miyachi, Y. Katsumi, K. Kikuchi, K. Tsuchiya, S. Osone, H. Kuroda, T. Sugimoto, T. Sawada, and H. Hosoi, "Preoperative Analysis of 11q Loss Using Circulating Tumor-released DNA in Serum: A Novel Diagnostic Tool for Therapy Stratification of Neuroblastoma," Cancer Lett., 309 [2] 185-89 (2011).   DOI