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http://dx.doi.org/10.3746/jkfn.2002.31.5.796

Effects of Eucommia ulmoides olivon Ethanol Extract on Lipid Metabolism and Antioxidant Enzyme Activities of Rats Fed High Fat Diet  

남상명 (정인대학 호텔조리과)
강일준 (한림대학교 식품영양학과)
정차권 (한림대학교 식품영양학과)
정명은 (한림대학교 식품영양학과)
함승시 (강원대학교 식품생명공학부)
오덕환 (강원대학교 식품생명공학부)
Publication Information
Journal of the Korean Society of Food Science and Nutrition / v.31, no.5, 2002 , pp. 796-801 More about this Journal
Abstract
To investigate the effects of Ewomia ulmoides olivon extract on the serum and hepatic lipid status and anti-oxidant enzyme activities, male Sprague Dawley (SD) rats were given high fat diets and Eucomia ulmoides olivon ethanol extracts for 6 weeks. Rats were divided into (our groups consisting the control (C), Eucomia ulmoides oliuon extract fed group (CE), high fat diet group (CL) and the extract and high fat fed group (CLE). Eucomia ulmoides oliuon ethanol extract lowered total cholesterol, but increased HDL-cholesterol and HDL-cholesterol/total cholesterol of the serum compared to the control. On the other hand, the ratio of HDL-cholesterol/total cho-lcsterol (HTR) was increased by 55% (p<0.05). High fat diet significantly increased serum cholesterol contents, but decreased HDL-cholesterol level and HTR (p<0.05). Atherogenic index (AI) of CL group was increased by almost four times of the control (p<0.05). Triglycerides (TG) and phospholipids were also increased by high fat diet. Eucomia ulmoides oliuon ethanol extract decreased the levels of TG (p<0.05) and phospholipids (p<0.05). Although liver antioxidant engyme activities including glutathione sulfur transferase (GST), superoxide dismutase (SOD) and catalase were decreased by high fat diet, those were stimulated by the administration of Eucommia ulmoides olivon ethanol extract.
Keywords
Eucommia ulmoides olivon; cholesterol; triglyceride; SOD; GST; catalase;
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