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http://dx.doi.org/10.5352/JLS.2005.15.2.242

The Effects of Hijikia fusiforme on Serum Lipid Levels in Ovariectomized Rats  

Kim Jeang-Yub (Dept. of Food Science and Nutrition, Silla University)
Kim Mihyang (Dept. of Food Science and Nutrition, Silla University)
Publication Information
Journal of Life Science / v.15, no.2, 2005 , pp. 242-247 More about this Journal
Abstract
The aim of this study was evaluated the effect of biological activity of Hijikia fusiforme (HF). To investigate the effects of biological activity of HF ethanol extracts, Sprague-Dawley female rats were randomly assigned to the following groups: sham-operated rats (Sham), ovariectomized control rats (OVX-control), ovariectomized rats supplemented ethanol extracts of HF at 50 mg/kg bw/day (OVX-HF50), ovariectomized rats supplemented ethanol extracts of HF at 200 mg/kg bw/day (OVX-HF200). HF ethanol extracts were orally supplemented at the level of 1 mL per day. The body weight gain, food intake and food efficiency ratio were not significantly different between groups. Although total-cholesterol and triglyceride were increased in the ovariectomized control, supplementation with the HF extracts decreased the levels. And HDL-cholesterol levels were significantly increased after supplementation with the HF extracts $(p<0.05)$. According to these results, we could known the effects biological activity of Hijikia fusiforme. Consequently, we expect the effects of Hijikia fusiforme extract on cardiovascular diseases aging coming from postmenopausal.
Keywords
Hijikia fusiforme; ovariectomized rat; serum lipids;
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