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http://dx.doi.org/10.5762/KAIS.2017.18.4.183

Effect of Walking Exercise with Blood Flow Restriction on Body Composition, Growth Hormone, and Muscle Damage Markers in Obese Women  

Lee, Jang-Kyu (Dept. of Exercise Prescription & Rehabilitation, Dankook University)
Publication Information
Journal of the Korea Academia-Industrial cooperation Society / v.18, no.4, 2017 , pp. 183-190 More about this Journal
Abstract
Blood flow restriction(BFR) exercise is defined as low and short lengthexercise with pneumatic pressure belts at the top of the limbs. This study was conducted to investigate the effects of walking exercise with BFR on body composition, growth hormone, and muscle damage markers in obese women. Eleven obese women(> BMI 25kg/m2&> body fat 30%) wore pneumatic pressure belts at both femurs and performed walking exercise twice per day, 3days/wk for 4 week (walking 2min; resting 1min). Body weight, BMI and body fat significantly decreased after exercise(p<0.05), while% body fat was slightly decreased after exercise, although this difference was not significant. Growth hormones increased slightly after exercise, although not significantly. Muscle damage markers (CK(p<0.05), LDH(p<0.05) and K+(p<0.01 increased significantly after exercise, but Mb was did not change significantly. These results suggest that 4-weeks ofblood flow restriction exercisecould be used to prevent and treat obesity and related chronic diseases, as well as metabolic syndrome. Moreover, the effects were similar to those observed in response to high intensity resistance programs, despite the short period for which BFR were conducted.
Keywords
blood flow restriction; body composition; creatine kinase; growth hormone; lactate dehydrogenase; myoglobin; potassium;
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1 Takarada, Y., Nakamura, Y., Aruga, S., Onda, T., Miyazaki, S., & Ishii, N, "Rapid increase in plasma growth hormone after low-intensity resistance exercise with vascular occlusion", J Appl Physiol, 88, pp. 61-65, 2000.   DOI
2 Park, S. H., Ryu, H. S., & Kwon, Y. W, "Exercise and Healthy". Pegasus press, Seoul, Korea. (2014).
3 Itoh, H., Ohkuwa, T., Yamazaki, Y., S himoda, T., Wakyama, A., Tamura, S., Yamamoto, T., Sato Y., & Miyamura, M, "Vitamin E supplementation attenuates leakage of enzymes following 6 successive days of running training", International Journal of Sports Medicine, 21, no. 5, pp. 369-374, 2000. DOI: https://doi.org/10.1055/s-2000-3777   DOI
4 Van Hall, G, "Lactate as a fuel for mitochondrial respiration. Acta Physiologica Scandinavica, 168, no. 4, pp. 643-656, 2000. DOI: https://doi.org/10.1046/j.1365-201x.2000.00716.x   DOI
5 Falvo, M. J., & Bloomer, R. J, "Review of exercise -induced muscle injury: Relevance for athletic populations", Research in Sports Medicine, 14, no. 1, pp. 65-82, 2006. DOI: https://doi.org/10.1080/15438620500528380   DOI
6 Godin, G., Desharnais, R., Valois, P., Lepage, L., Jobin, J., & Bradet, R, "Differences in perceived barriers to exercise between high and low intenders: observations among different populations. Am J Health Promotion. 8, pp. 279-284, 1994. DOI: https://doi.org/10.4278/0890-1171-8.4.279   DOI
7 Trost, S. G., Owen, N., Bauman, A. E., Sallis, J. F., & Brown, W, "Correlates of adults' participation in physical activity: review and update", Med Sci Sports Exerc. 34, pp. 1996-2001, 2002. DOI: https://doi.org/10.1097/00005768-200212000-00020   DOI
8 Marcus, B. H., Williams, D. M., Dubbert, P. M., Sallis, J. F., King, A. C., Yancey, A. K., Franklin, B. A., Buchner, D., Daniels, S. R., & Claytor, R. P., American Heart Association Council on Nutrition, Physical Activity, and Metabolism (Subcommittee on Physical Activity).;American Heart Association Council on Cardiovascular Disease in the Young; Interdisciplinary Working Group on Quality of Care and Outcomes Research.. "Physical activity intervention studies: what we know and what we need to know: a scientific statement from the American Heart Association Council on Nutrition, Physical Activity, and Metabolism (Subcommittee on Physical Activity); Council on Cardiovascular Disease in the Young; and the Interdisciplinary Working Group on Quality of Care and Outcomes Research, Circulation, 12;114, no. 24, pp. 2739-52. Review, Erratum in: Circulation, 2010 Jul 6;122, no. 1, pp. e8.2006.   DOI
9 Jackson, A. S., Pollock, M. L., & Waed, A, "Generalized equations for predicting body density of women", Med Sci Sports Exerc, 12, no. 3, pp. 175-181, 1980. DOI: https://doi.org/10.1249/00005768-198023000-00009
10 Siri, W, E, "Body composition from fluid spaces and densities :analysis of methods, In Brozek, J., Henschel, A.(eds, pp. Techniques for Measuring Body. Composition", Washington DC, National Academy of Sciences, 223-244, 1961.
11 Sato, Y., Ishii, N., Nakajima, T., & Abe, T, "KAATSU Training. Theoretical and Practical Perspectives", goudan co, 2007.
12 Booth, F. W., & Thomason, R. B, "Molecular and cellular adaptation of muscle in response to exercise: perspective of various models. Physiological reviews, 71, no. 2, pp. 541-585, 1991.   DOI
13 Takarada, Y., & Ishii, N, "Effects of low-intensity resistance exercise the shortest rest period on muscular function in middle-aged women", J Strength Cond Res, 16, pp. 123-128, 2002. DOI: https://doi.org/10.1519/00124278-200202000-00019
14 Choi, H. M., & Lee, D. J, "Effect of Pressurization Training with Walking on Body Composition, Respiratory Function, and Cardiovascular Response in Middle-Aged Obese Women", Journal of Life Science, 22, no. 4, pp. 545-551, 2012. DOI: https://doi.org/10.5352/JLS.2012.22.4.545   DOI
15 Seo, H. T., Ko, I. T., Kim, H. J., & Nho, H. S, "The effect of pressurization training with 2weeks term physical fitness and skeletal muscle function in elite snowboard athletes", The korea journal of sports science, 3, no. 4, pp. 1211-18, 2014.
16 Hamilton, M T., & Booth, F. W, "Skeletal muscle adaptation to exercise: a century of progress", Journal of applied physiology, 88, no. 1, pp. 327-332, 2000.   DOI
17 Holloszy, J. O., & Booth, F. W., "Biochemical adaptations to endurance exercise in muscle", Annual review of physiology, 38, pp. 273-291, 1976. DOI: https://doi.org/10.1146/annurev.ph.38.030176.001421   DOI
18 Scacchi, M., Pincelli, AI., & Cavagnini, F, "Growth hormone in obesity", Int J Obes Relat Metab Disord. 23, no. 3, pp. 260-71, 1999. DOI: https://doi.org/10.1038/sj.ijo.0800807   DOI
19 Veldhuis, J. D., Iranmanesh, A., Ho, K. K., Waters, M. J., Johnson, M. L., & Lizarralde, G, "Dual defects in pulsatile growth hormone secretion and clearance subserve the hyposomatotropism of obesity in man", J Clin Endocrinol Metab. 72, no. 1, pp. 51-9, 1991. DOI: https://doi.org/10.1210/jcem-72-1-51   DOI
20 Godfrey, R. J., Madgwick, Z., & Whyte, G. P, "The exercise-induced growth hormone response in athletes", Sports Med, 33, no. 8, pp. 599-613, 2003. DOI: https://doi.org/10.2165/00007256-200333080-00005   DOI
21 Ozaki, H., Loenneke, J. P., & Abe, T, "Blood flow-restricted walking in older women: does the acute hormonal response associate with muscle hypertrophy?", Clin Physiol Funct Imaging, Oct 30. [Epub ahead of print], 2015. DOI: https://doi.org/10.1111/cpf.12312
22 Williams, T., Berelowitz, M., Joffe, S. N., Thorner, M. O., Rivier, J., Vale, W., & Frohman, L. A, "Impaired growth hormone responses to growth hormone-releasing factor in obesity. A pituitary defect reversed with weight reduction", N Engl J Med, 29, no. 22, pp. 1403-7, 1984. DOI: https://doi.org/10.1056/NEJM198411293112203
23 Tanaka, K., Inoue, S., Numata, K., Okazaki, H., Nakamura, S., & Takamura, Y, "Very-low calorie diet-induced weight reduction reverses impaired growth hormone secretion response to growth hormone-releasing hormone, arginine, and L-dopa in obesity", Metabolism, 39, no. 9, pp. 892-6, 1990. DOI: https://doi.org/10.1016/0026-0495(90)90296-O   DOI
24 Rasmussen, M. H., Hvidberg, A., Juul, A., Main, K. M., Gotfredsen, A., Skakkebaek, N. E., Hilsted, J., & Skakkebae, N. E, "Massive weight loss restores 24-hour growth hormone release profiles an serum insulin-like growth factor-I levels in obese subjects", J Clin Endocrinol Metab, 80, no. 8, pp. 2446, 1995. DOI: https://doi.org/10.1210/jcem.80.4.7536210
25 Clarkson, P. M., & Hubal, M. J, "Exercise-induced muscle damage in humans", Am J Phys Med Rehabil, 81, no. 11 Suppl, pp. S52-69, 2002. DOI: https://doi.org/10.1097/00002060-200211001-00007   DOI
26 Sayers, S. P., & Clarkson, P. M, "Exercise-induced rhabdomyolysis", Curr Sports Med Rep, 1, no. 2, pp. 59-60, 2002. DOI: https://doi.org/10.1249/00149619-200204000-00001   DOI
27 Marieb, E. N, "Human anatomy and physiology", third edition, pp:856. The benjamin/cumming publishing company. california. USA, 1995.
28 Proske, U., & Morgan, D. L, "Muscle damage from eccentric exercise: mechanism, mechanical signs, adaptation and clinical applications", J Physiol, 537(Pt2, pp. 333-45, 2001. DOI: https://doi.org/10.1111/j.1469-7793.2001.00333.x   DOI
29 Clarkson, P. M., Kearns, A. K., Rouzier, P., Rubin, R., & Thompson, P. D, "Serum creatine kinase levels and renal function measures in exertional muscle damage", Med Sci Sports Exerc, 38, no. 4, pp. 623-7, 2006. DOI: https://doi.org/10.1249/01.mss.0000210192.49210.fc   DOI
30 Nosaka, K., & Clarkson, P. M, "Changes in indicators of inflammation after eccentric exercise of the elbow flexors. Med Sci Sports Exerc, 28, no. 8, pp. 953-61, 1996. DOI: https://doi.org/10.1097/00005768-199608000-00003   DOI
31 Piitulainen, H., Komi, P., Linnamo, V., & Avela, J, "Sarcolemmal excitability as investigated with M-waves after eccentric exercise in humans", J Electromyogr Kinesiol, 18, no. 4, pp. 672-81, 2008. DOI: https://doi.org/10.1016/j.jelekin.2007.01.004   DOI
32 Sejersted, O. M., & Sjogaard, G, "Dynamics and consequences of potassium shifts in skeletal muscle and heart during exercise", Physiol Rev, 80, no. 4, pp. 1411-81, 2000.   DOI
33 Friden, J., Sjostrom, M., & Ekblom, B, "A morphological study of delayed muscle soreness", Experientia. 15;37, no. 5, pp. 506-7, 1981.   DOI
34 Barash, I. A., Peters, D., Friden, J., Lutz, G. J., & Lieber, R. L, "Desmin cytoskeletal modifications after a bout of eccentric exercise in the rat", Am J Physiol Regul Integr Comp Physiol, 283, no. 4, pp. R958-63, 2002. DOI: https://doi.org/10.1152/ajpregu.00185.2002   DOI
35 Beekley, M. D., Sato, Y., & Abe, T, "KAATSU-walk training increases serum bone-specific alkaline phosphatase in youn men", Int J KAATSU training Res, 1, pp. 77-81, 2005.   DOI
36 Warren, G. L., Ingalls, C. P., Lowe, D. A., & Armstrong, R. B, "Excitation-contraction uncoupling: major role in contraction-induced muscle injury", Exerc Sport Sci Rev, 29, no. 2, pp. 82-7, 2001. DOI: https://doi.org/10.1097/00003677-200104000-00008   DOI
37 Lee, J., & Clarkson, P. M, "Plasma creatine kinase activity and glutathione after eccentric exercise. Med Sci Sports Exerc, 35, no. 6, pp. 930-6, 2003. DOI: https://doi.org/10.1249/01.MSS.0000069553.47739.36   DOI
38 Kim, K. S., Park, S. H., Huh, Y., & Park, M. R, "Search for the trend of study and possibility of field application on resistance training with blood flow restriction", The Korean Journal of Sports Science, 20, no. 5, pp. 1047-1065, 2011.
39 American College of Sports Medicine, "Guidelines for Exercise Testing and Prescription, 7th, Baltomore, MI : Lippincott Williams & Wilkins, 2006.
40 Weiss, L. W., Cureton. K. J., & Thompson, F. N, "Comparison of serum testosterone androstenedione responses to weight lifting in men and women", European Journal of Applied Physioligy and Occupational Physiology. 50, no. 3, pp. 413-419, 1983. DOI: https://doi.org/10.1007/BF00423247   DOI
41 Katch, F. I., & Drumm, S. S, "Effects of different modes of strength training on body composition and anthropometry", Clin Sports Med, 5, no. 3, pp. 413-59, 1986.
42 Haykowsky, M. J., Findlay, J. M., & Ignaszewski, A. P, "Aneurysmal sub-ara chnoid hemorrhage associated with weight training:three case reports", Clin J Sport Med, 6, pp. 52-55, 1996. DOI: https://doi.org/10.1097/00042752-199601000-00011   DOI
43 Abe, T., Kearns, C. F., & Sato, Y, "Muscle size and strength are increased following walk training with restricted venous blood flow from the leg muscle, Kaatsu-walk training", J Appl Physiol (1985), 2006 May;100, no. 5, pp. 1460-6, Erratum in: J Appl Physiol. 2008, 104, no. 4, pp. 1255, 2005.   DOI
44 Takano, H., Morita, T., Iida, H., Asada, K., Kato, M., Uno, K., Hirose, K., Matsumoto, A., Takenaka, K., Hirata, Y., Eto, F., Nagai, R., Sato, Y., & Nakajima, T, "Hemodynamic and hormonal responses to a short-term low intensity resistance exercise with the reduction of muscle blood flow", Eur J Appl Physiol, 95, pp. 65-73, 2005. DOI: https://doi.org/10.1007/s00421-005-1389-1   DOI
45 Takarada, Y., Tsuruta, T., & Ishii, N, "Cooperative effects of exercise and occlusive stimuli on muscular function in low-intensity resistance exercise with moderate vascular occlusion", Jap J Physiol, 54, pp. 585-92, 2004. DOI: https://doi.org/10.2170/jjphysiol.54.585   DOI
46 Hamdy, R. C., Anderson, J. S., Whalen, K. E., & Harvill, L. M, "Regional differences in bone density of young men involved in different exercises", Med Sci Sports Exerc. 26, no. 7, pp. 884-8, 1994. DOI: https://doi.org/10.1249/00005768-199407000-00012
47 Donnelly, J. E., Honas, J. J., Smith, B. K., Mayo, M. S., Gibson, C. A., Sullivan, D. K., Lee, J., Herrmann, S. D., Lambourne, K., Washburn, R. A, "Aerobic exercise alone results in clinically significant weight loss for men and women: midwest exercise trial 2", Obesity, 21, no. 3, pp. E219-28, 2013. DOI: https://doi.org/10.1002/oby.20145   DOI
48 Rosenkilde, M., Auerbach, P., Reichkendler, M. H., Ploug, T., Stallknecht, B. M., & Sjodin, A, "Body fat loss and compensatory mechanisms in response to different doses of aerobic exercise--a randomized controlled trial in overweight sedentary males", Am J Physiol Regul Integr Comp Physiol, 15;303, no. 6, pp. R571-9, 2012.   DOI
49 Han, C. S., Lee, G. S., Lee, M. S., & Hwang, H. J, "The Effect of Changing the Order of Exercise Types on Body Composition and Blood Lipid in Obese Women". Korea Academia- Industrial cooperation Society, 10, no. 12, pp. 3888-3894, 2009. DOI: http://doi.org/10.5762/KAIS.2009.10.12.3888   DOI
50 Lee, D. H., Oh, D. H., Zhang, S. A., Lee, J. K, "Effect of Exercise Type and Intensity on Insulin Resistance and Cardiovascular Disease Risk Factors in Obese Middle Aged Women" Korea Academia- Industrial cooperation Society, 17, no. 6, pp. 181-191, 2016. DOI: http://doi.org/10.5762/KAIS.2016.17.6.181