Are PIK3CA Mutation and Amplification Associated with Clinicopathological Characteristics of Gastric Cancer? |
Lee, Hyunsu
(Department of Anatomy, Keimyung University College of Medicine)
Hwang, Il-Seon (Department of Pathology,Keimyung University College of Medicine) Choi, In-Jang (Department of Anatomy, Keimyung University College of Medicine) Kang, Yu-Na (Department of Pathology,Keimyung University College of Medicine) Park, Keon-Uk (Division of Hematology/Oncology, Department of Internal Medicine, Keimyung University College of Medicine) Lee, Jae-Ho (Department of Anatomy, Keimyung University College of Medicine) |
1 | Bertelsen BI, Steine SJ, Sandvei R, Molven A, Laerum OD (2006). Molecular analysis of the PI3K-AKT pathway in uterine cervical neoplasia: frequent PIK3CA amplification and AKT phosphorylation. Int J Cancer, 118, 1877-83. DOI |
2 | Byun DS, Cho K, Ryu BK, et al (2003). Frequent monoallelic deletion of PTEN and its reciprocal associatioin with PIK3CA amplification in gastric carcinoma. Int J Cancer, 104, 318-27. DOI ScienceOn |
3 | Campbell IG, Russell SE, Choong DY, et al (2004). Mutation of the PIK3CA gene in ovarian and breast cancer. Cancer Res, 64, 7678-81. DOI |
4 | Cancer Genome Atlas Research N (2014). Comprehensive molecular characterization of gastric adenocarcinoma. Nature, 513, 202-9. DOI |
5 | Correa P (1992). Human gastric carcinogenesis: a multistep and multifactorial process-first American cancer society award lecture on cancer epidemiology and prevention. Cancer Res, 52, 6735-40. |
6 | Correa P, Shiao YH (1994). Phenotypic and genotypic events in gastric carcinogenesis. Cancer Res, 54, 1941-3. |
7 | Garcia-Rostan G, Costa AM, Pereira-Castro I, et al (2005). Mutation of the PIK3CA gene in anaplastic thyroid cancer. Cancer Res, 65, 10199-207. DOI |
8 | Gray JW, Collins C (2000). Genome changes and gene expression in human solid tumors. Carcinogenesis, 21, 443-52. DOI |
9 | Kandula M, Chennaboina KK, Ammi Raju Y, Raju S (2013). Phosphatidylinositol 3-kinase (PI3KCA) oncogene mutation analysis and gene expression profiling in primary breast cancer patients. Asian Pac J Cancer Prev, 14, 5067-72. DOI |
10 | Kato S, Iida S, Higuchi T, et al (2007). PIK3CA mutation is predictive of poor survival in patients with colorectal cancer. Int J Cancer, 121, 1771-8. DOI |
11 | Lee JW, Soung YH, Kim SY, et al (2005). PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas. Oncogene, 24, 1477-80. DOI |
12 | Leung WK, Kim JJ, Kim JG, Graham DY, Sepulveda AR (2000). Microsatellite instability in gastric intestinal metaplasia in patients with and without gastric cancer. Am J Pathol, 156, 537-43. DOI |
13 | Lin Y, Jiang X, Shen Y, et al (2009). Frequent mutations and amplifications of the PIK3CA gene in pituitary tumors. Endocr Relat Cancer, 16, 301-10. |
14 | Ma YY, Wei SJ, Lin YC, et al (2000). PIK3CA as an oncogene in cervical cancer. Oncogene, 19, 2739-44. DOI |
15 | Samuels Y, Wang Z, Bardelli A, et al (2004). High frequency of mutations of the PIK3CA gene in human cancers. Science, 304, 554. DOI ScienceOn |
16 | Michl P, Downward J (2005). Mechanisms of disease: PI3K/ AKT signaling in gastrointestinal cancers. Z Gastroenterol, 43, 1133-9. DOI |
17 | Ottini L, Falchetti M, Lupi R, et al (2006). Patterns of genomic instability in gastric cancer: clinical implications and perspectives. Ann Oncol, 17, 97-102. DOI |
18 | Qu JL, Qu XJ, Zhao MF, et al (2009). Gastric cancer exosomes promote tumour cell proliferation through PI3K/Akt and MAPK/ERK activation. Dig Liver Dis, 41, 875-80. DOI |
19 | Shayesteh L, Lu Y, Kuo WL, et al (1999). PIK3CA is implicated as an oncogene in ovarian cancer. Nat Genet, 21, 99-102. DOI |
20 | Shi J, Yao D, Liu W, et al (2012). Highly frequent PIK3CA amplification is associated with poor prognosis in gastric cancer. BMC Cancer, 12, 50. DOI |
21 | Velho S, Oliveira C, Ferreira A, et al (2005). The prevalence of PIK3CA mutations in gastric and colon cancer. Eur J Cancer, 41, 1649-54. DOI ScienceOn |
22 | Wu G, Xing M, Mambo E, et al (2005). Somatic mutation and gain of copy number of PIK3CA in human breast cancer. Breast Cancer Res, 7, 609-16. DOI |
23 | Yamamoto H, Shigematsu H, Nomura M, et al (2008). PIK3CA mutations and copy number gains in human lung cancers. Cancer Res, 68, 6913-21. DOI |
24 | Yamamoto S, Tsuda H, Takano M, et al (2011). PIK3CA mutation is an early event in the development of endometriosisassociated ovarian clear cell adenocarcinoma. J Pathol, 225, 189-94. DOI |
25 | Zhang D, Wang Z, Luo Y, et al (2011). Analysis of DNA copy number aberrations by multiple ligation-dependent probe amplification on 50 intestinal type gastric cancers. J Surg Oncol, 103, 124-32. DOI |
26 | Yu HG, Ai YW, Yu LL, et al (2008). Phosphoinositide 3-kinase/Akt pathway plays an important role in chemoresistance of gastric cancer cells against etoposide and doxorubicin induced cell death. Int J Cancer, 122, 433-43. DOI ScienceOn |