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http://dx.doi.org/10.7314/APJCP.2014.15.10.4193

Clinical Characteristics of Gynecologic Cancer Patients who Respond to Salvage Treatment with Lingzhi  

Suprasert, Prapaporn (Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University)
Apichartpiyakul, Chatchawann (Department of Microbiology, Faculty of Medicine, Chiang Mai University)
Sakonwasun, Choompone (Department of Microbiology, Faculty of Medicine, Chiang Mai University)
Nitisuwanraksa, Pimonphan (Research Administration Section, Faculty of Medicine, Chiang Mai University)
Phuackchantuck, Rochana (Research Administration Section, Faculty of Medicine, Chiang Mai University)
Publication Information
Asian Pacific Journal of Cancer Prevention / v.15, no.10, 2014 , pp. 4193-4196 More about this Journal
Abstract
Lingzhi or Ganoderma lucidum is a popular medicinal mushroom used as a health promotion herb in China and other Asian countries for thousands of years. There have many previous studies about the anti-cancer effects of lingzhi especially in vitro. The present study reports the clinical data of 5 gynecologic cancer patients who achieved stability in the disease after ingestion of lingzhi in the form of fruit body water extract and spores in a salvage setting. This report has been written to enhance the data describing the effect of lingzhi in cancer patients.
Keywords
Ganoderma lucidum; gynecologic cancer; salvage treatment;
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1 Zhao, Ye G, Fu G, et al (2011). Ganoderma lucidum exerts antitumor effects on ovarian cancer cells and enhances their sensitivity to cisplatin. Int J Oncol, 38, 1319-27.
2 Gao YH, Dai XH, Chen GL,et al (2003). A randomized, placebo-controlled, multicenter study of Ganoderma lucidum (W.Curt.: Fr.) Lloyd (Aphyllophoromycetideae) polysaccharides $(Ganopoly^{(R)})$ in patients with advanced lung cancer. Int J Med Mushr, 5, 369-81
3 Gao YH, Zhou SF, Jiang WQ,et al (2003). Effects of $Ganopoly^{(R)}$ (a Ganoderma lucidum polysaccharide extract) on the immune functions in advanced-stage cancer patients. Immunol Invest, 32, 201-15.   DOI   ScienceOn
4 Jin X, Ruiz Beguerie J, Sze DM, Chan GF (2012). Ganoderma lucidum (Reishi mushroom) for cancer treatment. Cochrane Database Syst Rev, 6, CD007731.
5 Li P, Deng YP, Wei XX, Xu JH (2013). Triterpenoids from Ganoderma lucidum and their cytotoxic activities. Nat Prod Res, 27, 17-22.   DOI
6 Martinez-Montemayor MM, Acevedo RR, Otero-Franqui E, Cubano LA, Dharmawardhane SF (2011). Ganoderma lucidum (Reishi) inhibits cancer cell growth and expression of key molecules in inflammatory breast cancer. Nutr Cancer, 63, 1085-94.   DOI
7 Wu G, Qian Z, Guo J, et al (2012). Ganoderma lucidum extract induces G1 cell cycle arrest, and apoptosis in human breast cancer cells. Am J Chin Med, 63, 631-42.
8 Wanmuang H, Leopairut J, Kositchaiwat C, Wananukul W, Bunyaratvej S (2007). Fatal fulminant hepatitis associated with Ganoderma lucidum (Lingzhi) mushroom powder. J Med Assoc Thai, 90, 179-81.
9 Wanachiwanawin D, Piankijagum A, Chaiprasert A, et al (2006). Ganoderma lucidum: a cause of pseudoparasitosis. Southeast Asian J Trop Med Public Health, 37, 1099-102.
10 Cancer Therapy Evaluation Program, Common Terminology Criteria for Adverse Events, Version 3.0 (2006), Available from: http://ctep.cancer.gov
11 Eisenhauer EA, Therasse P, Bogaerts J, et al (2009). New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). Eur J Cancer, 45, 228-47.   DOI   ScienceOn
12 Joseph S, Sabulal B, George V, Antony KR, Janardhanan KK (2011). Antitumor and anti-inflammatory activities of polysaccharides isolated from Ganoderma lucidum. Acta Pharm, 61, 335-42.