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http://dx.doi.org/10.7314/APJCP.2012.13.2.737

Microwave Ablation Treatment of Liver Cancer with a 2,450-MHz Cooled-shaft Antenna: Pilot Study on Safety and Efficacy  

Jiao, De-Chao (Department of interventional Radiology, The First Affiliated Hospital of Zhengzhou University)
Zhou, Qi (Department of Hepatobiliary Surgery, The First Affiliated Hospital of SunYat-sen University)
Han, Xin-Wei (Department of interventional Radiology, The First Affiliated Hospital of Zhengzhou University)
Wang, Ya-Feng (Department of Hepatobiliary Surgery, The First Affiliated Hospital of SunYat-sen University)
Wu, Gang (Department of interventional Radiology, The First Affiliated Hospital of Zhengzhou University)
Ren, Jian-Zhuang (Department of interventional Radiology, The First Affiliated Hospital of Zhengzhou University)
Wang, Yan-Li (Department of interventional Radiology, The First Affiliated Hospital of Zhengzhou University)
Ding, Peng-Xu (Department of interventional Radiology, The First Affiliated Hospital of Zhengzhou University)
Ma, Ji (Department of interventional Radiology, The First Affiliated Hospital of Zhengzhou University)
Fu, Ming-Ti (Department of interventional Radiology, The First Affiliated Hospital of Zhengzhou University)
Publication Information
Asian Pacific Journal of Cancer Prevention / v.13, no.2, 2012 , pp. 737-742 More about this Journal
Abstract
To evaluate efficacy of microwave ablation in a primary clinical study, sixty patients (44 men, 16 women; mean age 53 years) with 96, 1-8 cm (mean $3.20{\pm}0.17$ cm) liver cancers were treated with 2,450-MHz internally cooled-shaft antenna. Complete ablation (CA) and local tumor progression (LTP) rates as well as complications were determined. CA rates in small (< 3.0 cm), intermediate (3.1-5.0 cm) and large (5.1-8.0 cm) liver cancers were 96.4% (54/56), 92.3% (24/26) and 78.6% (11/14), respectively. During a mean follow-up period of $17.17{\pm}6.52$ months, LTP occurred in five (5.21%) treated cases. There was no significant difference in the CA and LTP rates between the HCC and liver metastasis patient subgroups (P<0.05). Microwave ablation provides a reliable, efficient, and safe technique to perform hepatic tumor ablation.
Keywords
Liver cancer; microwave ablation; clinical study; China;
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